• 대한약침학회지
• /
• 제25권4호
• /
• pp.317-325
• /
• 2022

Polymers are the major constructive material of pharmaceutical formulations that play a prime role in designing effective drug-delivery systems and releasing drugs at their sites of application. Polymers are composed of multiple repeating units of high molecular mass components with attendant properties. Most synthetic polymers are non-biocompatible, expensive, and extremely inclined to deliver adverse impacts. Meanwhile, edible polymers obtained from natural sources have gained remarkable recognition for their promising use in modern medicine. Moreover, polymers derived from natural sources are generally preferred due to certain of their unique features such as abundant availability, biocompatibility, nontoxicity, economical, safe, and effective functions that fit the purpose. Polysaccharides including starch, cellulose, hemicellulose, pectin, and mucilage are identified as a major class of naturally obtained molecules that have a substantial role as functional polymers. This review summarizes the potential role of polysaccharides derived from vegetable sources such as adhesives, anticaking agents, binders, disintegrants, emulsifiers, film-framing agents, and thickeners. This is simply an opportunity to abandon synthetic excipients that hurt our bodies and think back to nature from where we originate.

• 한국응용과학기술학회지
• /
• 제38권6호
• /
• pp.1678-1686
• /
• 2021

본 연구에서는 가교제인 붕산과 아크릴 수지 바인더에 삼인산(3 인산), 피트산(6 인산) 또는 폴리인산암모늄(10 인산)을 혼합하여 인계 난연 코팅액을 제조하였다. 제조된 인계 난연 코팅액을 부직포에 각각 코팅하여 높은 난연 효과를 얻었다. 이렇게 제조된 난연성 부직포를 연기밀도기준시험(ASTM E662), 산소한계지수기준시험(ISO E622), 수직연소기준시험(UL 94)을 이용하여 평가하였다. 그들의 난연 효과는 phosphate 그룹의 수에 의해 영향을 받았으며, 천연 또는 합성 바인더 수지에 관계없이 그 효과는 ammonium polyphosphate > phytic acid > triphosphate의 순서로 나타났다. 천연 탄화수소 화합물도 바인더 수지의 난연성을 결정하기 위해 조사되었다. 그 결과 천연 탄화수소 바인더 수지가 난연성 부직포 제조에 사용될 수 있음을 보여주었다.