• Title/Summary/Keyword: natural and synthetic binders

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Polysaccharides Obtained from Vegetables: an effective source of alternative excipient

  • Ananta Choudhury;Satyabrat Sarma;Snehashis Sarkar;Madhusmita Kumari;Biplab Kumar Dey
    • Journal of Pharmacopuncture
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    • v.25 no.4
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    • pp.317-325
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    • 2022
  • Polymers are the major constructive material of pharmaceutical formulations that play a prime role in designing effective drug-delivery systems and releasing drugs at their sites of application. Polymers are composed of multiple repeating units of high molecular mass components with attendant properties. Most synthetic polymers are non-biocompatible, expensive, and extremely inclined to deliver adverse impacts. Meanwhile, edible polymers obtained from natural sources have gained remarkable recognition for their promising use in modern medicine. Moreover, polymers derived from natural sources are generally preferred due to certain of their unique features such as abundant availability, biocompatibility, nontoxicity, economical, safe, and effective functions that fit the purpose. Polysaccharides including starch, cellulose, hemicellulose, pectin, and mucilage are identified as a major class of naturally obtained molecules that have a substantial role as functional polymers. This review summarizes the potential role of polysaccharides derived from vegetable sources such as adhesives, anticaking agents, binders, disintegrants, emulsifiers, film-framing agents, and thickeners. This is simply an opportunity to abandon synthetic excipients that hurt our bodies and think back to nature from where we originate.

Flame-retarding effects depending on the number of phosphonate groups attached to phosphorus flame-retarding compounds and coating binder resins (인계 난연화합물 및 코팅 바인더 수지에 부착된 phosphonate group에 따른 난연효과)

  • Park, Hyo-Nam;Kim, Hae-Rim;Choi, Seong-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.6
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    • pp.1678-1686
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    • 2021
  • In this study, we prepared phosphorous flame-retarding coating solutions by mixing triphosphate (3 phosphonate), phytic acid (6 phosphonate), or ammonium polyphosphate (10 phosphonate) with boric acid as a crosslinking agent and acryl resin binder. Prepared phosphorous flame-retarding coating solutions were coated onto non-woven fabrics, respectively, to obtain high flame-retarding effects. These prepared flame-retardant non-woven fabrics were evaluated using smoke density standard test (ASTM E662), limit oxygen index standard test (ISO E622), and vertical burning standard test (UL 94). Their flame-retarding effects were affected by the number of phosphonate groups. Regardless of natural or synthetic binder resins, their effects showed the following order: ammonium polyphosphate > phytic acid > triphosphate. Natural hydrocarbon compounds were also examined to determine the possible retardancy of binder resins. Results showed that natural hydrocarbon binder resins could be used for preparing fire-retardant nonwoven fabrics.