• Archives of Plastic Surgery
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• 제38권3호
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• pp.251-256
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• 2011

Purpose: A nasolabial cyst is a rare non-odontogenic, soft-tissue, developmental cyst arising anywhere on the face inferior to the nasoalar region. It is thought to arise from either epithelial remnants trapped along the lines of fusion during the development of face or the remnants of the developing nasolacrimal duct. This study examines various features of nasolabial cysts with bony involvement to provide a basis for correct diagnosis and treatment. Methods: Eight cases of nasolabial cyst treated in Soonchunhyang Hospital between March 2002 and July 2010 were examined in terms of their clinical features and radiological and histological findings. Seven patients underwent surgical excision of the cyst via an intraoral, sublabial approach. One underwent incision and drainage. Results: Our eight patients were seven women and one man. The most frequent symptoms and signs were facial deformity and swelling of the nasolabial fold. Computed tomography (CT) showed a well-circumscribed cystic mass lateral to the pyriform aperture. Seven cases had erosive lesions on CT, and the intraoperative findings were consistent with a nasolabial cyst with a bony defect. Typical histopathological findings showed that these cysts were most frequently lined with respiratory epithelium with ciliated columnar cells and cuboid cells. No patient developed complications or recurrences. Conclusion: A nasolabial cyst is often unrecognized or confused with other intranasal masses, including fissural and odontogenic cysts, midface infections, or swelling in the nasolabial area. Therefore, a careful clinical and radiological evaluation should be preformed when considering the differential diagnosis. We present eight patients with nasolabial cysts treated via a gingivobuccal approach with excellent functional and cosmetic results.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제27권3호
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• pp.266-270
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• 2001

구강악안면 영역에 발생한 foreign body impaction은 흔하지 않지만, 일단 발생하면 즉시 제거되어야 하며 술후 후유증을 충분히 방지하기위해 주의깊은 병력청취, 임상 검사, 방사선 사진을 이용한 localization이 꼭 필요하다. 그리고 수술시에는 조심스럽게 조직을 박리하고 전체 손상부위를 철저히 탐진해서 foreign body를 제거해야 한다. 저자등은 침구용 바늘, nasolacrimal ductoplasty용 silicone tube, 산탄 총알등 다양한 구강 악안면영역에서 발견된 이물질을 제거한 경험후 문헌고찰과 함께 보고하는 바이다.

• Journal of Industrial and Engineering Chemistry
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• 제68권
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• pp.229-237
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• 2018

Medical silicone tubes are generally used as implants for the treatment of nasolacrimal duct stenosis. However, side effects such as allergic reactions and bacterial infections have been reported following the silicone tube insertion, which cause surgical failure. These drawbacks can be overcome by modifying the silicone tube surface using a functional coating. Here, we report a biocompatible and superhydrophilic surface coating based on a polysaccharide multilayer nanofilm, which can load and release antibacterial and anti-inflammatory agents. The nanofilm is composed of carboxymethylcellulose (CMC) and chitosan (CHI), and fabricated by layer-by-layer (LbL) assembly. The LbL-assembled CMC/CHI multilayer films exhibited superhydrophilic properties, owing to the rough and porous structure obtained by a crosslinking process. The surface coated with the superhydrophilic CMC/CHI multilayer film initially exhibited antibacterial activity by preventing the adhesion of bacteria, followed by further enhanced antibacterial effects upon releasing the loaded antibacterial agent. In addition, inflammatory cytokine assays demonstrated the ability of the coating to deliver anti-inflammatory agents. The versatile nanocoating endows the surface with anti-adhesion and drug-delivery capabilities, with potential applications in the biomedical field. Therefore, we attempted to coat the nanofilm on the surface of an ophthalmic silicone tube to produce a multifunctional tube suitable for patient-specific treatment.

• Korean Journal of Ophthalmology
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• 제32권6호
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• pp.438-444
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• 2018

Purpose: To compare the success rates of performing only silicone tube intubation versus carrying out both conjunctival resection and silicone tube intubation. Methods: The subjects of this study involved 62 patients (96 eyes) between October 2015 and May 2017 who were diagnosed as having punctal stricture or nasolacrimal duct stenosis. Out of 96 eyes, 47 underwent only silicone tube intubation, and 49 underwent both silicone tube intubation and conjunctival resection. Three parameters were measured at 1, 3, and 6 months after the surgery: the area of the tear meniscus using RTVue-100 anterior segment optical coherence tomography, the height of the tear meniscus using a slit lamp microscope, and the subjective satisfaction of patients as a result of improved sympotms like epiphora. The surgery was considered successful when the patients' experienced the resolution of symptoms and reduction of the area and height of the tear meniscus. Results: The area of the tear meniscus, height of the tear meniscus, and subjective satisfaction of patients was superior in the group that underwent both silicone tube intubation and conjunctival resection compared silicone tube intubation only. Based on these results, the success rate of the surgery was 68.9% in the group that underwent only silicone tube intubation and 78.7% in the group that underwent both silicone tube intubation and conjunctival resection. Conclusions: The resection of relaxed plica semilunares seems to increase the success rate of silicone tube intubation through the reduction of the area and height of the tear meniscus. Therefore, after determining the degree of conjunctivochalasis, if it was found to be severe, a combination with conjunctival resection was expected to increase the success rate of the surgery.

• 고신대학교 의과대학 학술지
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• 제33권3호
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• pp.358-368
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• 2018

Objectives: To identify the relationship between surgical success rate and preoperative nasal mucosal thickness around the lacrimal sac fossa, as measured using computed tomography. Methods: We reviewed 33 eyes from 27 patients who underwent endoscopic dacryocystorhinostomy after diagnosis of primary nasolacrimal duct obstruction and who were followed-up with for at least six months between 2011 and 2014. We measured preoperative nasal mucosal thickness around the bony lacrimal sac fossa using computed tomography and analyzed patient measurements after classifying them into three groups: the successfully operated group, the failed operation group, and the non-operated group. Results: Surgery failed in six of the 33 eyes because of a granuloma at the osteotomy site and synechial formation of the nasal mucosa. The failed-surgery group showed a clinically significantly greater decrease in nasal mucosal thickness at the rearward lacrimal sac fossa compared with the successful-surgery group. However, nasal mucosal thickness of fellow eyes (i.e., non-operated eyes) was not significantly different between the two groups, and the location of the uncinate process did not appear to influence mucosal thickness. In the failed group, posteriorly located mucosal thickness of operated eye fossa was thinner than that of the non-operated eyes, but not significantly so. Conclusions: Our results from this quantitative anatomical study suggest that nasal mucosal thickness is a predictor of endoscopic dacryocystorhinostomy results.

• 대한안과학회지
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• 제59권11호
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• pp.1001-1008
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• 2018

목적: 눈물길미세내시경을 이용한 실리콘관삽입술과 기존의 코내시경만으로 시행한 방법 간의 성공률을 비교하고자 하였다. 대상과 방법: 2014년 1월부터 2017년 6월까지 본원에서 실리콘관삽입술을 시행한 환자들을 대상으로 하였다. 술 전 눈물소관 관류검사와 눈물주머니조영술로 진단하였다. 술 후 3개월 때 실리콘관을 제거하였고 4, 12개월 때 성공률을 내시경 사용에 따라 두 군으로 나눠 분석하였다. 결과: 총 55명, 80안으로 술 전 진단에서 사용군은 부분폐쇄 26안, 완전폐쇄 14안, 미사용군은 부분폐쇄 35안, 완전폐쇄 5안이었다(p=0.018). 술 후 4, 12개월 때 성공률은 사용군에서는 87.5%, 80.0%, 미사용군에서는 72.0%, 62.1%였다(p=0.546, p=0.565). 부분폐쇄에서 사용군과 미사용군의 성공률은 4개월 때 92.3%, 82.9%, 12개월 때 71.4%, 62.9% (p=0.448, p=1.000), 완전폐쇄에서 성공률은 4개월 때 78.6%, 60.0%, 12개월 때 72.7%, 33.3%였다(p=0.570, p=0.505). 눈물길미세내시경의 사용과 폐쇄의 위치 및 정도의 차이가 술 후 4, 12개월 때 성공률에 유의한 영향을 미침을 확인하였다(p=0.001, p=0.022). 결론: 눈물길미세내시경을 이용한 실리콘관삽입술은 기존의 것에 비하여 성공률이 유의하게 높지는 않았으나, 코눈물길의 구조를 실시간으로 확인하여 적절한 진단 및 치료가 동시에 가능하다. 완전폐쇄로 진단되었던 환자들에게도 좋은 성공률을 보여 그 적용 범위를 확대시켜 비침습적인 치료를 시행할 수 있을 것이다.

• 한국임상수의학회지
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• 제32권3호
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• pp.235-238
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• 2015

서울에서 개의 안과질환에 대한 역학적인 특징에 대해 2009년 1월부터 2013년 12월까지우성동물메디칼센터에 안과질환으로 내원한 초진환자들의 자료를 분석하였다. 총 1253두의 안과환자들이 초진 내원하였으며, 평균나이는 7.93년령 (SD, 4.06)이었다. 환자중에 Shih Tzu (29.4%)가 가장 많았으며, Maltese, Yorkshire Terrier, Cocker Spaniel, toy Poodle (P < 0.01)이 뒤를 따랐다. 눈에서 질병이 호발하는 곳은 수정체 관련 질환이 가장 많았으며 (28.3%), 안검질환, 망막질환, 비루관질환, 포도막질환, 유리체질환, 시신경계 질환이 그 뒤를 따랐다(P < 0.01). 수정체, 안검, 망막, 비루관, 포도막, 유리체, 시신경계 질환들은 주로 양측성 질환(P < 0.01)으로 발생하는 경향을 보였다. Shih Tzu에서는 각막질환이 가장 많이 발생하였으며, 수정체, 안검, 망막, 녹내장 질환이 그 뒤를 따랐다. Maltese에서는 수정체, 안검, 망막, 각막질환의 순으로 질병이 발생했다. Yorkshire Terrier, Cocker Spaniel, 그리고 toy Poodle 종은 수정체 질환이 가장 많았다(P < 0.01). 안과질환으로 병원에 내원하는 주된 환자들은 Shih Tzu, Maltese, Yorkshire Terrier등과 같은 소형견들이었고, 대부분 수정체 질환과 같은 품종소인이 있는 질환이 대부분이었다.