• Title/Summary/Keyword: nano-filtering process

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Anti-adipogenic Effects of Dongchimi Nano Juice in Mouse 3T3-L1 Adipocytes

  • Kong, Chang-Suk;Lee, Sun-Hyun;Seo, Jung-Ok;Park, Kun-Young;Rhee, Sook-Hee
    • Preventive Nutrition and Food Science
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    • v.11 no.4
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    • pp.285-288
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    • 2006
  • The anti-adipogenic effect of dongchimi nano juice prepared using a nano-filtering process was investigated by measuring leptin and glycerol levels and the expression of a peroxisome proliferator-activated $receptor-\gamma\;(PPAR\gamma)$ gene as indicators of lipid accumulation or lipolysis. Red pepper powder, seeds of red pepper, garlic, and ginger were added in the preparation of dongchimi. Dongchimi was fermented to reach the optimal fermentation period, followed by nano-filtration in the range of $0.0005\sim0.1\;{\mu}m$. The lactic acid bacteria of dongchimi nano juice were removed completely by a nano-filtering process. Treatment of dongchimi nano juice induced glycerol release in the 3T3-L1 adipocytes and decreased the mRNA expression level of $PPAR\gamma$. These results suggested that dongchimi nano juice may enhance lipolysis and modulate adipogenesis in 3T3-L1 cells.

Precise Estimations on Vorticities using a Hybrid PTV-PIV Algorithm (하이브리드 PTV-PIV알고리듬에 의한 고정밀 와도 추정)

  • Doh, Deog-Hee;Cho, Gyong-Rae;Lee, Jae-Min
    • Journal of the Korean Society of Visualization
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    • v.8 no.4
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    • pp.26-30
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    • 2010
  • A PTV algorithm was constructed using a linear transformation, in which the merits of the conventional PIV and PTV were adopted. In PIV calculations, the obtained velocity vectors are affected by the filtering effects by its calculation principle. PTV techniques are widely used for their excellences of measuring small scaled flows, such as nano and bio flows. However, PTVs produce vector errors due to interpolation process. To overcome these problems, a hybrid PTV algorithm was constructed by combining PTVs' and PIVs' benefits using a linear transformation. The Taylor-Green vortex flows were generated for the tests of vorticity calculations. The conventional gray-level cross-correlation PIV technique and 2-Frame PTV technique were tested for the same flows for comparisons with those obtained by the constructed hybrid algorithm. The excellence of the constructed hybrid algorithm was validated through an actual experiment on the cylinder wake.

Structural Analysis & Phase Transition of Amorphous Silica Nanoparticles Using Energy-Filtering TEM (EF-TEM을 이용한 비정질 실리카 나노입자의 구조 및 상전이 연구)

  • Park, Jong-Il;Kim, Jin-Gyu;Song, Ji-Ho;Kim, Youn-Joong
    • Applied Microscopy
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    • v.34 no.1
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    • pp.23-29
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    • 2004
  • In this study, we introduce the structural analysis of amorphous silica nanoparticles by EF-TEM electron diffraction and in-situ heating experiments. Three diffused rings were observed on the electron diffraction patterns of initial silica nanoparticles, while crystalline spot patterns were gradually appeared during the insitu heating process at $900^{\circ}C$. These patterns indicate the basic unit of $SiO_4$ tetrahedra consisting amorphous silica and gradual crystallization into the ideal layer structure of tridymite by heating. Under high vacuum condition in TEM, SiO nanoparticles were redeposited on the carbon grid after evaporation of SiO gas from $SiO_2$ above $850^{\circ}C$ and the remaining $SiO_2$ were crystallized into orthorhombic tridymite, consistent with ex-situ heating results in furnace at $900^{\circ}C$.

Drug Delivery System Using Electrospun Nanofiber Mats (전기방사된 나노파이버 매트를 이용한 약물전달시스템에 관한 연구)

  • Yoon, Hyeon;Park, Yoon-Kyung;Kim, Geun-Hyung
    • Polymer(Korea)
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    • v.33 no.3
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    • pp.219-223
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    • 2009
  • The nanofibers fabricated by using an electrohydrodynamic process has been used as various applications, such as nano-device, filtering system, protective clothes, wound dressing, and drug delivery system (DDS). Of these applications, the DDS should be needed to minimize side effects of drugs, maximize the properties of medicine, and efficiently deliver the required amount of drugs to the diseased area. In this paper, by using the electro spinning process, which is one of electrohydrodynamic processes, two different types, polycarprolactone and poly(ethylene oxide)/Rhodamine B, of electrospun mats were fabricated layer by layer and the release behavior of Rhodamine B was characterized with time. In addition, to show the feasibility of DDS of this type, we tested release behavior of a peptide of the nanofiber system, a PCL/(Peptide+PEO)/PCL nanofiber mat. The released peptide did not loss biological activities. From these results, we believe that the layered nanofiber mat as a DDS has enough function of a new drug delivery system.

The Study of Nano-vesicle Coated Powder (나노베시클 표면처리 분체의 개발연구)

  • Son, Hong-Ha;Kwak, Taek-Jong;Kim, Kyung-Seob;Lee, Sang-Min;Lee, Cheon-Koo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.32 no.1 s.55
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    • pp.45-51
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    • 2006
  • In the field of makeup cosmetics, especially, powder-based foundations such as two-way cake, pact and face powder, the quality of which is known to be strongly influenced by the properties of powder, surface treatment technology is widely used as a method to improve the various characteristics of powder texture, wear properties, dispersion ability and so on. The two-way cake or pressed-powder foundation is one of the familiar makeup products in Asian market for deep covering and finishing purpose. In spite of the relent progress in surface modification method such as composition of powders with different characteristics and application of a diversity of coating ingredient (metal soap, amino acid, silicone and fluorine), this product possess a technical difficulty to enhance both of the adhesion power and spreadability on the skin in addition to potential claim of consumer about heavy or thick feeling. This article is covering the preparation and coating method of nano-vesicle that mimic the double-layered lipid lamellar structure existing between the corneocytes of the stratum corneum in the skin for the purpose of improving both of two important physical characteristic of two-way cake, spreadability and adhering force to skin, and obtining better affinity to skin. Nano-vesicle was prepared using the high-pressure emulsifying process of lecithin, pseudo ceramide, butylene glycol and tocopheryl acetate. This nano-sized emulsion was added to powder-dispersed aqueous phase together with bivalent metal salt solution and then the filtering and drying procedure was followed to yield the nano-vesicle coated powder. The amount of nano-vesicle coated on the powder was able to regulated by the concentration of metal salt and this novel powder showed the lower friction coefficient, more uniform condition of application and higher adhesive powder comparing with the alkyl silane treated powder from the test result of spreadability and wear properties using friction meter and air jet method. Two-wav cake containing newly developed coated powder with nano-vesicle showed the similar advantages in the frictional and adhesive characteristics.