• Journal of the Korean Ceramic Society
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• v.50 no.4
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• pp.275-279
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• 2013

The purpose of this study was to prepare calcium phosphate cement [CPC] for use in artificial bone. Nano-crystalline calcium phosphate [CaP] was precipitated at $37^{\circ}C$ using highly active $Ca(OH)_2$ in DI water and an aqueous solution of $H_3PO_4$. From the XRD measurements, the nano-CaP powder was close to apatitic TCP phase and the powders fired at $800^{\circ}C$ showed a critical ${\beta}$-TCP phase. A mixture of one mole $CaCO_3$ and two moles di-calcium phosphate was calcined at $1100^{\circ}C$ to make a reference ${\beta}$-TCP material. The nano-CaP powders were added to the normal ${\beta}$-TCP matrix and fired at $900^{\circ}C$ to make a ${\beta}$-TCP block. The sintered block showed improved mechanical strength, which was caused by the solid state interaction between nano-CaP and normal ${\beta}$-TCP.

• Journal of the Korean Ceramic Society
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• v.53 no.6
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• pp.670-675
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• 2016

Calcium phosphate crystallites were prepared by wet chemical method for use in artificial bone. In order to obtain ${\beta}$-tricalcium phosphate (TCP), nano-crystalline calcium phosphate (CaP) was precipitated at $37^{\circ}C$ and at $pH5.0{\pm}0.1$ under stirring using highly active $Ca(OH)_2$ in DI water and an aqueous solution of $H_3PO_4$. The precipitated nano-crystalline CaP solution was kept at $90^{\circ}C$ for the growth of CaP crystallites. Through the growing process of CaP crystallites, we were able to obtain various sizes of rectangular CaP crystallites according to the crystal growing times. Dry nano-crystalline CaP powders at $37^{\circ}C$ were mixed with dry macro-crystalline CaP crystallites and the shaped mixture sample was fired at $1150^{\circ}C$ to make a ${\beta}-TCP$ block. Several tens of nm powders were uniformly coated on the surface, which was comprised of powders of several tens of ${\mu}m$, using a vibrator. The mixing ratio between the nanometer powders and the micrometer powders greatly affected the mechanical strength of the mixture block; the most appropriate ratio of these two materials was 50 wt% to 50 wt%. The sintered block showed improved mechanical strength, which was caused by the solid state interaction between the nano-crystalline ${\beta}-TCP$ and the macro-crystalline ${\beta}-TCP$.

• Proceedings of the Materials Research Society of Korea Conference
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• 2002.05a
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• pp.161-161
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• 2002

• Proceedings of the Korean Magnestics Society Conference
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• 2003.06a
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• pp.202-203
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• 2003

• Proceedings of the Korean Magnestics Society Conference
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• 2004.06a
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• pp.114-115
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• 2004

• Proceedings of the Materials Research Society of Korea Conference
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• 2005.05a
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• pp.312-312
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• 2005

• Korean Journal of Materials Research
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• v.17 no.9
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• pp.480-483
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• 2007

Hydroxyapatites were prepared by the different $SiO_2$ addition at $1450^{\circ}C$ for 2h. With the increase of $SiO_2$ addition, microstructure, bulk density, porosity, mechanical strength of $hydroxyapatite/{\beta}-TCP$ composite were investigated. When the sintered HAp contained 1 wt% $SiO_2$, the each properties of the HAp were increased. But the excess addition of $SiO_2$ content above 1wt% the each property were decreased. This results were due to the ${\beta}-TCP$ phase. The ${\beta}-TCP$ phase appeared at 3 wt% $SiO_2$ addition and the ${\beta}-TCP$ phase was enhanced by the $SiO_2$ increasing.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2008.10a
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• pp.9-10
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• 2008

Tricrecyl phosphate(TCP)-containing polyurea microcapsules were prepared by interfacial polymerization using aromatic 2,4-toluene diisocyanate(TDI) and Ethylene diamine(EDA) as wall forming materials. The effects of the protective colloids of polyvinylalcohol(PVA) and gelatin were investigated through experimentation.

• Proceedings of the Korea Information Processing Society Conference
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• 2007.05a
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• pp.867-869
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• 2007

TinyOS기반 무선센서노드를 사용한 실시간 계측 데이터 측정 및 제어기술은 유비쿼터스 센서 네트워크 분야에 주로 사용되어 왔으나 다양한 응용이나 신뢰성 있는 무선 네트워크 연구 개발에 한계가 있는 것으로 알려져 있다. 본 논문에서는 ATMega128L을 장착한 최소 8대 이상의 nano-24 센서 노드모듈과 메모리 용량이 매우 제한적인 무선 센서 노드에 적합하다고 평가받고 있는 Nano-Q+를 사용하여 전시물 주변의 환경 정보를 실시간 측정하는 시스템을 구현하였다. 전시물 주변의 센서들은 하나의 PAN Coordinator를 중심으로 Start-Mesh 네트워크를 구성하여 환경 정보를 측정한다. 환경 정보를 전송 하기 위해 측정된 계측 데이터를 센서 네트워크의 PAN Coordinator 노드로부터 환경 모니터링 서버로 효율적으로 전송하기 위한 TCP기반 전송 프로그램을 구현하였다. 실험 결과 센서 노드 수와 관련된 PAN의 크기 및 샘플링 주기에 상관없이 안정적으로 계측 데이터 수신이 이루어짐을 확인 하였다.

• Journal of the Korean Ceramic Society
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• v.45 no.10
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• pp.618-624
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• 2008

Various calcium phosphate bioceramics are distinguished by their excellent biocompatibility and osteoconductivity. Especially, the exceptional biodegradability of $\beta$-TCP makes it a bone graft substitute of choice in many clinical applications. The activation of osteoclasts, differentiated from macrophage precursor cells, trigger a cell-mediated resorption mechanism that renders $\beta$-TCP biodegradable. Based on this evidence, we studied the biodegradation process of granular-type $\beta$-TCP bone graft substitute through in vitro and in vivo studies. Raw 264.7 cells treated with RANKL and M-CSF differentiated into osteoclasts with macrophage-like properties, as observed with TRAP stain. These osteoclasts were cultured with $\beta$-TCP nano powders synthesized by microwave-assisted process. We confirmed the phagocytosis of osteoclasts by observing $\beta$-TCP particles in their phagosomes via electron microscopy. No damage to the osteoclasts during phagocytosis was observed, nor did the $\beta$-TCP powders show any sign of cytotoxicity. We also observed the histological changes in subcutaneous tissues of rats implanted with granule-type $\beta$-TCP synthesized by fibrous monolithic process. The $\beta$-TCP bone graft substitute was well surrounded with fibrous tissue, and 4 months after implantation, 60% of its mass had been biodegraded. Also, histological findings via H&E stain showed a higher level of infiltration of lymphocytes as well as macrophages around the granule-type $\beta$-TCP. From the results, we have concluded that macrophages play an important role in the biodegradation process of $\beta$-TCP bone graft substitutes.