• 제목/요약/키워드: n-Paraffin

검색결과 139건 처리시간 0.026초

Biocompatibility and bioactive potential of the NeoMTA Plus endodontic bioceramic-based sealer

  • Roberto Alameda Hoshino;Mateus Machado Delfino;Guilherme Ferreira da Silva;Juliane Maria Guerreiro-Tanomaru;Mario Tanomaru-Filho;Estela Sasso-Cerri;Paulo Sergio Cerri
    • Restorative Dentistry and Endodontics
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    • 제46권1호
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    • pp.4.1-4.16
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    • 2021
  • Objectives: This study evaluated the biocompatibility and bioactive potential of NeoMTA Plus mixed as a root canal sealer in comparison with MTA Fillapex. Materials and Methods: Polyethylene tubes filled with NeoMTA Plus (n = 20), MTA Fillapex (n = 20), or nothing (control group, CG; n = 20) were inserted into the connective tissue in the dorsal subcutaneous layer of rats. After 7, 15, 30 and 60 days, the specimens were processed for paraffin embedding. The capsule thickness, collagen content, and number of inflammatory cells (ICs) and interleukin-6 (IL-6) immunolabeled cells were measured. von Kossa-positive structures were evaluated and unstained sections were analyzed under polarized light. Two-way analysis of variance was performed, followed by the post hoc Tukey test (p ≤ 0.05). Results: At 7 days, the capsules around NeoMTA Plus and MTA Fillapex had more ICs and IL-6-immunostained cells than the CG. However, at 60 days, there was no significant difference in the IC number between NeoMTA Plus and the CG (p = 0.1137) or the MTA Fillapex group (p = 0.4062), although a greater number of IL-6-immunostained cells was observed in the MTA Fillapex group (p = 0.0353). From 7 to 60 days, the capsule thickness of the NeoMTA Plus and MTA Fillapex specimens significantly decreased, concomitantly with an increase in the collagen content. The capsules around root canal sealers showed positivity to the von Kossa stain and birefringent structures. Conclusions: The NeoMTA Plus root canal sealer is biocompatible and exhibits bioactive potential.

Anti-tumor Initiating Potential of Andrographolide in 7,12-dimethylbenz[a]anthracene Induced Hamster Buccal Pouch Carcinogenesis

  • Manoharan, S.;Singh, Arjun Kumar;Suresh, K.;Vasudevan, K.;Subhasini, R.;Baskaran, N.
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권11호
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    • pp.5701-5708
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    • 2012
  • The aim of the study was to investigate the chemopreventive potential of andrographolide in 7,12-dimethylbenz(a) anthracene (DMBA)-induced hamster buccal pouch carcinogenesis. Oral tumors developed in the buccal pouch of golden Syrian hamsters at a 100% incidence on painting with 0.5% DMBA in liquid paraffin three times a week for 14 weeks. Marked abnormalities in the status of detoxification enzymes, lipid perxodiation and antioxidants were noticed in hamsters treated with DMBA alone. Oral administration of andrographolide at a dose of 50 mg/kg bw to hamsters treated with DMBA not only completely prevented the tumor formation but also restored the status of the above mentioned biomarkers. The present study thus demonstrates the chemopreventive potential of andrographolide in DMBA-induced hamster buccal pouch carcinogenesis, which is probably due to its antioxidant potential as well as modulating effect on xenobiotic metabolising enzymes during DMBA-induced oral carcinogenesis.

In Situ Hybridization에 의한 돼지 유행성설사증 (Porcine Epidemic Diarrhea)의 진단 (Rapid and Easy Detection of Porcine Epidemic Diarrhea Virus (PEDV) by in situ Hybridization)

  • 박남용;조호성;김태주;박영석
    • 대한수의학회지
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    • 제43권3호
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    • pp.477-483
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    • 2003
  • Molecular diagnostic techniques have been used to identify porcine epidemic diarrhea virus (PEDV), a causative agent of acute enteritis in swine, but they were difficult to be petformed and time-consuming. To detect PEDV in a rapid and easy way, we developed biotinylated cDNA probe for N gene encoding the nucleoproteins of PEDV. Formalin-fixed and paraffin-embedded tissues from 24 naturally infected pigs were used for the experiment. The ISH produced a positive reaction in all cases. When intestinal tissues were hybridized with PEDV probe, strong signals were seen in the villus enterocytes of the jejunum and ileum. Hybridization signals were also found in the duodenum from one pig and in colon from dnother. In conclusion, ISH with a biotinylated cDNA probe was provided to be a useful diagnostic method for detecting PEDV effectively in routinely processed tissue sections.

상변화 물질을 사용한 축열조에서의 열전달 - 수직원관에서의 내향용융 실험 - (Heat Transfer in Heat Storage System with P.C.M. - Inward Melting in a Vertical Tube)

  • 손화승;황태인;이채문;최국광;임장순
    • 태양에너지
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    • 제9권1호
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    • pp.53-61
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    • 1989
  • In the present investigation, experiments on the melting of a phase change material were performed to research heat transfer phenomena generated by means of conduction and natural convection in the vertical tube at inward melting. The phase change material used in the experiments is 99 percent pure n-Docosane paraffin which is measured melting temperature of $42.5^{\circ}C$, latent heat of 37.5 cal/g, heat conductivity of $0.1505W/m^{\circ}C$. Experiments were performed both in the no-subcooling which is initiating it at melting temperature of phase change material, and in the subcooling which means to initiate it under melting temperature of phase change material, in order to compare and investigate the horizontal temperature history, vertical temperature history, ratio of melting and melted mass, figure of the melting front in the vertical tube. In the experimental results, heat transfer from tube wall to phase change material were due to conduction at early stage and due to natural convection with the passage of time, and then occurred melting downward from surface by volumetric expansion. Natural convection affects temperature distribution in the tube, ratio of melting and melted mass, figure of the melting front and then progress rapidly in case of nosubcooling compared to subcooling.

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통증(痛症)의 한방치료(韓方治療)에 관(關)한 소고(小考) (A Study on the treatment of pain in oriental medicine)

  • 류경주
    • 한국한의학연구원논문집
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    • 제2권1호
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    • pp.454-484
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    • 1996
  • There are many factors to evoke pain, for example cold, heat, seven emotion, digestion, fatigue, venemous worms, deficiency of blood etc., and its pathogenesis is complicated. Treatments for pain in oriental medicine are as follows. 1. Pharmacotherapy is a method to treat pain by different effects of herbal medicine, for example, regulating vital energy, activating blood circulation, eliminating phlegm, and dispelling the cold evil etc. 2. Acupuncture and moxibustion therapy is a kind of external application, it has a distinct effect in relieving pain. Recently its operation method has been more developed, so new acupuncture therapies are used in clinics. There are electroacupuncture, auricular acupuncture and injection of drugs at an acupuncture points etc. 3. Oriental physiotherapy is a treatment method to stimulate acupuncture points and meridians. (1) Hot pack, Paraffin bath, Microwave, Ultrasound, Short wave, Infra-red etc. are used to treat cold syndrome by dispersing cold by warming the channels. (2) E.S.T., I.C.T., T.E.N.S., S.S.P., cupping treatment etc. are used to treat disorders of vital energy. (3) Health ion, Carbon, T.D.P., etc are used to treat conic and deficiency syndrome.

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혼합 용매계 저독성 농축형 유분산제의 제조와 광유에 대한 분산효율 특성 (Preparation and Properties of Mixed Solvent Type Low Toxic Concentrated Oil Dispersant on Oil)

  • 염규설;강두환;김원기
    • 한국응용과학기술학회지
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    • 제14권3호
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    • pp.29-38
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    • 1997
  • Low toxic concentrated oil dispersant using n-Paraffin and Di(ethylene glycol)mono butylether mixed solvent was prepared, and tested by oil dispersant performance test method, and oil dispersant efficiency was measured using vertical shaking method to 3 kinds of Crude oil, Bunker oil and W/O emulsions with different physical properties by appling the prepared dispersant. Although toxicity test was performed with Flat fish and Rock fish by appling the mixed oils emulsified using prepared oil dispersant, couldn't find the toxicity to them. Concentrated oil dispersant prepared has a good dispersion efficiency of 97.2% after 0.5min settling time and 28.3% after 10min settling time to Bunker B oil with 10% water solution. Especially, the concentrated oil dispersant showing the low toxicity to Oryzias Latipes(24hr, TLm) was 54,000 ppm and to Brine Shrimp Artemia(24hr, TLm) was 51,000ppm, and also, it was completely biodegradated to 99.1% after $7{\sim}8$days.

수직냉각관내에서 상변화물질의 응고에 관한 실험적 연구 (An Experimental Study on Freezing of Phase Change Material in a Cooled Vertical Tube)

  • 이재목;이채문;임장순
    • 대한설비공학회지:설비저널
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    • 제13권4호
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    • pp.223-229
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    • 1984
  • Experiments were performed for freezing of an initially superheated or nonsuperheated liquid phase in a cooled vertical tube. The liquid was placed in a copper tube whose surface maintained a uniform temperature during the data run and the freezing occurred in a copper tube. The phase change medium was n-odtadecane, a paraffin which freezes at about $61^{\circ}C$. Measurements were made which yielded information about the time dependence of the freezing front, of the amount of frozen mass, and of the various energy components extracted from the tube. The time-wise decay of the initial liquid superheat was also measured. Initial superheat of the liquid tends to moderately diminish the rozen mass and associated latent energy extraction at small times but has lit tie effect on these quantities at large tiems. Natural convection in the liquid Plays a modest role only at small times and disappears when the superheat decay to zero. Although the latent energy constitutes the largest contributor to the total extracted energy, the sensible energy components can make a significant contribution, especially at large tube wall subcoolings, large initial liquid superheating and short freezing time.

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Measurement of the applicability of various experimental materials in a medically relevant reactor neutron source part two: Study of H3BO3 and B-DTPA under neutron irradiation

  • Ezddin Hutli;Peter Zagyvai
    • Nuclear Engineering and Technology
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    • 제55권7호
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    • pp.2419-2431
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    • 2023
  • Experiments related to Boron Neutron Capture Therapy (BNCT) accomplished at the Institute of Nuclear Techniques (INT), Budapest University of Technology and Economics (TUB) are presented. Relevant investigations are required before designing BNCT for vivo applications. Samples of relevant boron compounds (H3BO3, BDTPA) usually employed in BNCT were investigated with neutron beam. Channel #5 in the research reactor (100 kW) of INT-TUB provides the neutron beam. Boron samples are mounted on a carrier for neutron irradiation. The particle attenuation of several carrier materials was investigated, and the one with the lowest attenuation was selected. The effects of boron compound type, mass, and compound phase state were also investigated. To detect the emitted charged particles, a traditional ZnS(Ag) detector was employed. The neutron beam's interaction with the detector-detecting layer is investigated. Graphite (as a moderator) was employed to change the neutron beam's characteristics. The fast neutron beam was also thermalized by placing a portable fast neutron source in a paraffin container and irradiating the H3BO3. The obtained results suggest that the direct measurement approach appears to be insufficiently sensitive for determining the radiation dose committed by the Alpha particles from the 10B (n,α) reaction. As a result, a new approach must be used.

실리카라이트 폼에 담지된 MFI 제올라이트 촉매의 제조와 n-옥탄 분해반응에서 이들의 촉매 성질 (Preparation of MFI Zeolite Catalyst Supported on Silicalite Foam and Its Catalytic Property in the Cracking of n-Octane)

  • 정재식;최동배;송경근;하광;송요순;서곤
    • Korean Chemical Engineering Research
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    • 제43권4호
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    • pp.452-457
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    • 2005
  • 실리카라이트 폼에 $0.2{\mu}m$ 정도의 가는 MFI 제올라이트 입자를 담지하여 만든 폼(foam) 촉매에서 n-옥탄의 분해반응을 조사하였으며, 생성물 분포에 Delplot 기법을 적용하여 반응기구를 고찰하였다. 담지된 MFI 제올라이트의 Si/Al 몰비는 25로 추정되며, 담지량은 실리카라이트 폼의 25 wt%이었다. 겉보기 밀도는 $0.11g{\cdot}cm^{-3}$로 낮아 촉매 충전량을 0.02 g에서부터 0.5 g까지 바꿀 수 있어서 압력손실 없이 반응물과 생성물의 체류시간을 폭 넓게 조절하였다. 촉매 충전량이 많아지면 n-옥탄의 전환율과 올레핀 수율이 높아졌다. 촉매를 조금 사용하였을 때 생성물 분포는 단순하여 양성자 분해기구로 설명할 수 있었다. 촉매 사용량이 많아지면 분해 생성물의 추가 반응이 진행되어 반응성이 낮은 올레핀과 파라핀의 함량이 많아지며 생성물 분포가 복잡해졌다.

치과대학 대학생 타액의 치아 우식활성도 평가(I) (A Study on Dental Caries Activity Assessment from Saliva of Students of Dentistry College (I))

  • 손승화;김동애;박영민
    • 치위생과학회지
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    • 제13권2호
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    • pp.182-190
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    • 2013
  • 이 연구는 2012년 11월 12일부터 11월 30일까지 D대학교에 재학 중인 치과대학 대학생 100명을 대상으로 타액을 채취하여 타액으로부터의 Streptococcus mutans 분포 정도를 측정한 후 치아 우식활성도를 분석하는 실험연구이다. 타액을 채취하기 전 간단한 자기기입식 설문지를 작성하였고, paraffin을 1분간 저작하여 타액을 컵에 모은 후 screening strip 전면에 타액이 충분하게 묻도록 하여 측정하였다. 연구 대상자의 일반적 특성을 파악하기 위해 빈도와 백분율을 산출하였고, 연구대상자의 흡연과 음주 유무 혹은 기간에 따라 치아 우식활성도의 연관성을 알아보기 위하여 빈도와 백분율, $x^2$ 검증을 통하여 파악한 결과는 다음과 같았다. 1. 연구대상자들의 50% 이상에서 치아 우식활성도 평가의 음성단계를 나타내고 있었다. 2. 흡연은 S. mutans의 분포에 영향을 미치고 있으며, 흡연 기간이 길어질수록 S. mutans가 많아짐에 따라 치아 우식활성도가 높아졌다. 3. 음주는 S. mutans의 분포에 크게 영향을 미치고 있으며, 음주 기간이 길어질수록 S. mutans가 많아짐에 따라 치아 우식활성도가 높아졌다. 4. 연구대상자의 흡연 및 음주유무, 성별에 따른 우식활성도의 평균 차이는 맨휘트니 유 검정을 사용하여 분석한 결과, 우식의 단계와 흡연 및 음주유무, 성별에 따라 치아우식에는 근사유의확률 양측의 값이 각각 0.476, 0.974, 0.772이었으며, 모두 통계학적인 유의성은 없었다. 결론적으로 빈도와 백분율을 흡연과 음주는 초기 우식 유발 세균인 S. mutans의 분포에 영향을 미치고 있는 것으로 나타났으나, 통계학적으로는 유의미한 차이는 없었다. 향후 관련된 여러 요인들을 모두 관리, 통제하거나 추가적으로 선별 투입한 실험연구를 통하여 구강건강을 위한 다양하고 더 많은 사례연구가 요청되고 있다.