• Journal of Pharmaceutical Investigation
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• v.33 no.2
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• pp.145-149
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• 2003

Manufacturing facilities of the pharmaceuticals must meet certain level of the cleanness required so that foreign substances such as dust, moisture, heat, microorganism, or virus do not contaminate the product. In case of radiopharmaceuticals for medical treatment and diagnosis, not only should the operators and environment be protected from radiation but also need to be isolated from the foreign contaminant. Therefore, manufacturing facilities for radiopharmaceuticals must satisfy the design standards of both hot cell and clean room which are specified by GMP. However, standards of maintaining negative pressure for preventing spread of radioactive contaminant in isolated facilities conflict with the standards of maintaining positive pressure for keeping cleanness. To solve this problem, air pressure of hot cell was designed lower than in the adjacent area to meet standards of the radiation safety. To keep higher cleanness in certain part of the hot cell for filling, minimal relative positive pressure allows. In order to effectively maintain the cleanness that is required for production of Tc-99m generator, which takes 70% of whole demand of radiopharmaceuticals, the rooms placed in each side of production room are used as a buffer area and three lead hot cells are installed in production room. In this research, we established the appropriate engineered design concept for Tc-99m generator manufacturing facility, which satisfies both GMP cleanness standard for preventing particles, bacteria, other contaminants and the regulations of radiation safety for supervising and controlling the amount of radiation exposure and exhausted radioactivity. And the concept of multi-barrier buffer zones is introduced to apply negative air pressure for hot cell with first priority and to continue relative positive air pressure for clean room.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2003.07a
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• pp.421-426
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• 2003

The Immunosensor based on antigen-antibody binding have been developed for detecting several analytes including antigen, small molecules, and cell. This method can be rapid and show very good detection limits. For Implementation of immunosensor, technologies for immobilization of antibody onto solid surface and detection of protein-protein binding must be developed. (an ellipsis)

• Journal of Korean Neurosurgical Society
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• v.50 no.4
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• pp.385-387
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• 2011

Leptomeningeal metastasis is a devastating complication of advanced stage cancer. It is frequently accompanied by hydrocephalus and intracranial hypertension that must be treated by ventriculoperitoneal shunts. However, there are actual risks of peritoneal seeding or accumulation of malignant ascites after the cerebrospinal fluid diversion procedure, though it has not been reported. Here, we present the case of a patient with non-small cell lung cancer with leptomeningeal metastasis in whom malignant ascites developed after a subduroperitoneal shunt.

• Proceedings of the KIEE Conference
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• 1989.07a
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• pp.557-560
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• 1989

For the purpose of increasing supply reliabiity in power line, high reliable voltage and current sensors must be needed. This paper describes the principle and result of the only optical voltage sensor based on BSO pockels cell.

• The Microorganisms and Industry
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• v.19 no.4
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• pp.14-26
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• 1993

Optimizing protein production in recombinant E. coli strains involves manipulation of genetic and environmental factors. In designing a production system, attention must be paid to gene expression efficiency, culture conditions and bioreactor configuration. Although not much emphasis was given to the physiology of host strains in this review, an understanding of the relationship between the physiology of host cell growth and the overproduction of a cloned gene protein is of primary importance to the improvement of the recombinant fermentation processes. Sometimes it is desirable to make use of gene fusion systems, e.g. protein A, polypeptide, gutathione-S-transferase, or pneumococcal murein hydrolase fusion, to facilitate protein purification.

• 한국신재생에너지학회:학술대회논문집
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• 2010.06a
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• pp.90.2-90.2
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• 2010

The crystalline silicon solar cells have been optical losses. but it can be reduced using light trapping by texture structure and anti-reflection coating. The high reflective index of crystalline silicon at solar wavelengths(400nm~1000nm) creates large reflection losses that must be compensated for by applying anti-reflection coating. In this study, the use of porous silicon(PSi) as an active material in a solar cell to take advantage of light trapping and blue-harvesting photoluminescence effect. Porous silicon is form by anodization and can be obtained in an electrolyte with hydrofluoric. We expect our research can results approaching to lower than 10% of several reflectance by porous silicon solar cells.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.939-942
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• 2004

In this study, we report simulation results of single-panel LCOS (liquid crystal on silicon). Reflective LCOS microdisplays are widely used in various projection and near-eye application. For one panel system, liquid crystal response time is an important variable. The panel must switch fast enough to support the display of Field color sequential with high field rates. In order to have fast response and good contrast, a vertical alignment (VA) cell was used in this study. With suitable selection on LC parameters like temperature, viscosity, elastic constant and birefringence, it is possible to get response time of around 2ms from a 2.0 um-thick vertical alignment cell. This result also indicates an ease of production control on 2.0 um cells than 1.0 um cells.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.19 no.40
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• pp.253-261
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• 1996

In optimizing the layout design of a multi-product assembly environment, tile analysis of the material flow is a vital ingredient. In flexible assembly systems, assembly time is usually very short thus the transfer time is relatively more important Therefore operations sequence must be so determined, that have no backtracking operations as possible as, It is important to form cells, so that they have no intercell movement in curring much processing delay, and to arrange machines as possible as densly. This study presents a independent cell formation method considering operation sequences and machine capacity in flexible assembly systems.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.10
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• pp.41-48
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• 2000

Manufacturing devices must be integrated for constructing CIM environment, but integration of heterogeneous system meets several economical and technological difficulties. In this case, MMS(Manufacturing Message Specification) can be an effective method, but it has problems which MMS products are generally very expensive and majority of the existing manufacturing devices do not support MMS. This paper describes the development of a gateway for Non-MMS-Compatible CNC machine tools to serve MMS and the implementation of OSI(Open System Interconnection) upper layer on TCP/IP. The developed system is applied to construct cell controller with heterogeneous devices under CIM environment and to evaluate interoperability and portability.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.26 no.11
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• pp.30-39
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• 2012

The characteristics of I-V and P-V of solar cell nonlinearly changes according to irradiation, temperature and load. Therefore, to use efficiently PV system, operating point must be always operating at maximum power point. Also, PV system is semiconductor, so it generates loss by temperature. But because of conventional MPPT methods are not considering temperature, it has problem which decrease efficiency. This paper proposes temperature measurement based optimal voltage(TMOV) MPPT algorithm using temperature measurement based optimal voltage. It analyzes characteristics of solar cell according to irradiation and temperature and conventional MPPT methods. The TMOV control algorithm proposed in this paper is compared and analyzed conventional MPPT methods. The validity of this paper proves using this result.