• Korean Journal of Pharmacognosy
• /
• v.33 no.1 s.128
• /
• pp.42-44
• /
• 2002

Three iridoid glycosides were isolated from the whole plant of Melampyrum setaceum var. nakaianum. On the basis of spectroscopic and chemical evidence, their structures were elucidated as mussaenoside, 10-benzoylcatalpol and melampyroside (10-benzoylaucubin).

• Korean Journal of Pharmacognosy
• /
• v.31 no.2
• /
• pp.157-162
• /
• 2000

The herb of Melampyrum roseum var. hirsutum Beauv. was extracted with methanol and the extract was fractionated with n-hexane, chloroform, ethylacetate and n-buthanol. Repeated column chromatography of silica gel, Sephadex LH-20 and Lobar-A lichroprep Si 60 led to the isolation of five compounds from n-hexane layer and ethylacetate layer. These compounds were identified as apigenin, linarin, pectolinarin, wogonin and mussaenoside, respectively, by the physicochemical and spectral properties.

• Korean Journal of Pharmacognosy
• /
• v.13 no.3
• /
• pp.106-111
• /
• 1982

Melampyrum roseum Max. is an annual herb in Scrophulariaceae plants. The materials were collected in Kyeongi-Do in 1980. The BuOH extract was evaporated under reduced pressure. The residue was column chromatographed over silica gel with benzene-MeOH (8 : 1) as an eluent and it gave the amorphus powder. Compound I has a molecular formula $C_{17}H_{26}O_{10}$ and it was identified as mussaenoside by chemical data, UV, IR, NMR spectra and compared with the authentic sample of mussaenoside tetraacetate.