• Korean Journal of Human Ecology
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• v.17 no.2
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• pp.315-333
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• 2008

This study aims at analyzing the characteristics of muscular men's somatotype to develop their clothing pattern. The body sizes of 168 men categorized as the muscular type according to the Somatotype Classification by Sheldon and Heath-Carter, were compared with the 5th Korean body size measurement (KBSM) conducted by SizeKorea in 2003, to analyze the characteristics of muscular men's somatotype. The results are as follows: 1. Compared to the 5th KBSM, the subject's body size is higher in the Chest, Upper Arm, Calf, Hip, and Thigh Circumference, and Thigh Thickness, and Waist Back and Biacromion Length, but lower in the Waist Circumference. 2. The subject group shows the characteristics of a wedge-shaped somatotype which has a broad chest and a slim waist, and of having a back more developed, longer and more curved, compared to the non-muscular men. 3. The study shows the subject group has the characteristics of both the wedged somatotype with wide chest and slim waist, and the X somatotype with projected hips and thighs.

• Physical Therapy Korea
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• v.22 no.3
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• pp.98-105
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• 2015

Muscular dystrophy is a hereditary musculoskeletal disorder caused by a mutation in the dystrophin gene. Duchenne muscular dystrophy (DMD) is one of the most common, and progresses relatively faster than other muscular dystrophies. It is characterized by progressive myofiber degeneration, muscle weakness and ultimately ambulatory loss. Since it is an X-linked recessive inheritance, DMD is mostly expressed in males and rarely expressed or less severe in females. The most effective measurement tool for DMD is magnetic resonance imaging (MRI), which allows non-invasive examination of longitudinal measurement. It can detect progressive decline of skeletal muscle size by measuring a maximal cross-sectional area of skeletal muscle. Additionally, other techniques in MRI, like $T_2$-weighted imaging, assess muscle damage, including inflammation, by detecting changes in $T_2$ relaxation time. Current MRI techniques even allow quantification of metabolic differences between affected and non-affected muscles in DMD. There is no current cure, but physical therapist can improve their quality of life by maintaining muscle strength and function, especially if treatment (and other forms of medical intervention) begins in the early stages of the disease.

• Journal of Korean Physical Therapy Science
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• v.2 no.4
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• pp.779-783
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• 1995

The number of the subjects of this study were all sixteen including 8 male and 8 female. They were chronic low back pain patients and treated at hospital out patient. The patients took lumbar extension strength training. The results of examination and analysis isometric lumbar extension muscular strength before and after the training are as follows; 1. TFT increased after lumbar extension muscular strength exercise than before the exercise. Inspire of difference of each angle. The reciprocal action didn't happen between training and angle. 2. NMT increased after lumbar extension muscular strength exercise than the before the exercise and the difference of each angle didn't happen. The reciprocal action also didn't happen between the training and angle. 3. Comparing presented standard point with individual point, 13persons' muscle strength of first step increased, on the other and 3 person's muscle strength a little increased in a same category. 4. The grade of low back pain decreased for all subjects. Concluding this study, lumbar extension muscular strength exercise through isokinetic device decreases the grade of low back pain and increase lumbar extension muscular strength. It is that equal exercise effect happen in full range of motion, for the exercise effect doesn't show the difference of each angle.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.522-525
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• 2005

The purpose of this study was to analyze the pattern of muscle usage during swing motion with a soft golf club in comparison with that with a normal golf club. The subjects were normal healthy young adults. The subjects performed swing motion using normal and soft golf clubs in turn. Then, we compared and analyzed the muscular activities for the two cases. The muscular activities of the subject was measured using MP100(BIOPAC Systems, Inc.). For the analysis of muscular activities, we measured EMG(Electromyography) of the subjects during swing motion. The muscles analyzed were deltoid, latissimus dorsi, external oblique, and rectus abdominis of the upper limbs and rectus femoris, biceps femoris, gastrocnemius, and soleus of the lower limbs. The result of the experiment showed that the pattern of muscle usage with soft golf club was similar to that with a normal golf club but the muscular activities with the soft golf was smaller than that with the normal golf club.

• Physical Therapy Rehabilitation Science
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• v.11 no.4
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• pp.598-603
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• 2022

Objective: About one-third of college students are exposed to stress to the point that their academic performance is negatively affected. To provide useful information for managing the mental health of young people by analyzing the perceived stress level, depression level, and life satisfaction according to the amount of physical activity and the level of muscular strength in male college students. Design: A cross-sectional study. Methods: Among 304 students who participated in the health exercise class at Sahmyook University in Seoul, the amount of physical activity and the level of muscular strength were divided into 3 quartiles, respectively, and the perceived stress level, depression level, and life satisfaction were analyzed through one-way ANOVA. The physical activity level and muscle strength level of the subjects were ranked, divided into 3 groups, and the difference in variables according to the group was verified. Results: There was no difference in perceived stress level, depression level, and life satisfaction according to the amount of physical activity, but statistically significant differences were shown in perceived stress scale(p=0.008) and life satisfaction(p=0.030) according to muscular strength. Conclusions: Policies to increase physical activity are important to improve and manage the mental health of young people, but it is judged to be more meaningful to provide an environment that can improve muscular strength.

• Korean Journal of Exercise Nutrition
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• v.13 no.3
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• pp.193-201
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• 2009

The purpose of this study was to examine the effects of combined exercise and creatine consumption to muscular function and pain in 24 middle-aged men in back pain patients. The patients were categorized into three groups; 8 patients underwent combined exercise alone, 8 patients underwent creatine consumption as well as combined exercise and the control group was 8 patients without these options. The follow-up period was 10 weeks doing aerobic exercise, resistance exercise or creatine consumption. The group that underwent creatine intake as well as combined exercise simultaneously showed significant increase on the 0°, 12°, 24°, 36°, 48°, 60° and 72° of back muscular power in the muscular function changes compared to control group, furthermore, it showed statistically significant improvement on the 24°, 36°, 48° and 60° in the combined exercise group compared to control group. However, between the group that underwent creatine consumption as well as combined exercise and the group that underwent combined exercise, the back muscular power was high in the all angles, but it was not statistically significant. The group that performed both creatine consumption and combined exercise showed pain relief relatively, comparing with either combined exercise or control group and the pain was also alleviated in the combined exercise group.

• Nutrition Research and Practice
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• v.12 no.2
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• pp.129-134
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• 2018

BACKGROUND/OBJECTIVES: Although several recent studies have reported the anti-cancer effects of extracts or components of Citrus unshiu peel, which has been used for various purposes in traditional medicine, the molecular mechanisms for their effects remain unclear. In the present study, the anti-cancer activity of a water-soluble extract of C. unshiu peel (WECU) in MDA-MB-231 human breast carcinoma cells at the level of apoptosis induction was investigated. MATERIALS/METHODS: Cytotoxicity was evaluated using the MTT assay. Apoptosis was detected using DAPI staining and flow cytometry analyses. Mitochondrial membrane potential, reactive oxygen species (ROS) assay, caspase activity and Western blotting were used to confirm the basis of apoptosis. RESULTS: The results indicated that WECU-induced apoptosis was related to the activation of caspase-8, and -9, representative initiator caspases of extrinsic and intrinsic apoptosis pathways, respectively, and caspase-3 accompanied by proteolytic degradation of poly(ADP-ribose) polymerase and down-regulation of the inhibitors of apoptosis protein family members. WECU also increased the pro-apoptotic BAX to anti-apoptotic BCL-2 ratio, loss of mitochondrial membrane potential and cytochrome c release from mitochondria to cytoplasm. Furthermore, WECU provoked the generation of ROS, but the reduction of cell viability and induction of apoptosis by WECU were prevented when ROS production was blocked by antioxidant N-acetyl cysteine. CONCLUSIONS: These results suggest that WECU suppressed proliferation of MDA-MB-231 cells by activating extrinsic and intrinsic apoptosis pathways in a ROS-dependent manner.

• Annals of Clinical Neurophysiology
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• v.6 no.2
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• pp.65-74
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• 2004

Limb-girdle muscular dystrophy (LGMD) is a heterogeneous group of inherited muscle disorders caused by the mutations of different genes encoding muscle proteins. In the past, when the molecular diagnostic techniques were not available, the subtypes of muscular dystrophies were classified by the pattern of muscle weakness and the mode of inheritance, and LGMD had been considered as a 'waste basket' of muscular dystrophy because many unrelated heterogeneous cases with 'limb-girdle' weakness were put into the category of LGMD. With the advent of molecular genetics at the end of the last century, it has been known that there are many subtypes of LGMD caused by the mutation of different genes, and now, LGMD is classified according to the results of the linkage analysis and the genes or proteins affected. Only small proportion (probably less than 10%) of LGMD is dominantly inherited, and autosomal dominant LGMD (AD-LGMD) consists of six subtypes (LGMD1A to 1F) so far. In autosomal recessive LGMD (AR-LGMD), more than 10 subtypes (LGMD2A to 2J) have been linked and most of the causative genes have been identified. Among AR-LGMDs, LGMD2A (calpain 3 deficiency), 2B (dysferlin deficiency), and sarcoglycanopathy (LGMD2C-2F) are major subtypes. The defective proteins in LGMDs are components of nuclear envelope, cytosol, sarcomere, or sarcolemma, and seem to play a different role in the pathogenesis of muscular dystrophy. It is notable that many causative genes of LGMDs are also responsible for other categories of muscular dystrophy or diseases affecting other tissue. However, by which mechanism they produce such a broad phenotypic variability is still unknown. The identification of mutation in the relevant gene is confirmative for the diagnosis, and is essential for genetic counseling and antenatal diagnosis of LGMD. Because many different genes are responsible for LGMD, differentiation of subtypes using immunohistochemistry and western blotting is the essential step toward the detection of mutation. For the effective research and medical care of the patients with muscular dystrophy in Korea, a research center with a medical facility supported by the government seems to be needed.

• Journal of Korean Clinical Health Science
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• v.3 no.2
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• pp.311-319
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• 2015

Purpose. This study of purpose was to compare and analyze the relationship among the isokinetic trunk muscular functions, flexibility and low back pain of elite weight lifter with regard of sex. Methods. we measured the level of low back pain, isokinetic muscular functions according to gender, then analyzed the relationship between isokinetic functions and the level of low back pain, between flexibility and the level of pain, between Athletic Career and the level. Results. In this study, the gender, the VAS point was $2.6{\pm}2.3$ and the VRS point was $2.3{\pm}1.3$ in males. The other side, in females the VAS points was $3.6{\pm}1.7$ and the VRS was $3.2{\pm}1.1$. There was significant negative correlation(r=-0.826) between the VAS point and the maximal flexion muscular strength per kilogram of $30^{\circ}/sec$ isokinetic exercise in female. also there was negative correlation between the muscular flexion strength per kilogram and the VRS point in female, but there was no significant relationship in male. Conclusions. In current study, these results suggested that the higher muscular flexion strength per kilogram is, the lower the level of low back pain is in female athletes. this is caused by the imbalance between Abdominal Muscles and Back Extensor in weight lifter. Therefore, there is the need to apply the program to improve the balance of trunk.

• Clinical and Experimental Pediatrics
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• v.61 no.2
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• pp.59-63
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• 2018

Purpose: Cardiomyopathy is becoming the leading cause of death in patients with Duchenne muscular dystrophy because mechanically assisted lung ventilation and assisted coughing have helped resolve respiratory complications. To clarify cardiopulmonary function, we compared cardiac function between the home ventilator-assisted and non-ventilator-assisted groups. Methods: We retrospectively reviewed patients with Duchenne muscular dystrophy from January 2010 to March 2016 at Gangnam Severance Hospital. Demographic characteristics, pulmonary function, and echocardiography data were investigated. Results: Fifty-four patients with Duchenne muscular dystrophy were divided into 2 groups: home ventilator-assisted and non-ventilator-assisted. The patients in the home ventilator group were older ($16.25{\pm}1.85years$) than those in the nonventilator group ($14.73{\pm}1.36years$) (P=0.001). Height, weight, and body surface area did not differ significantly between groups. The home ventilator group had a lower seated functional vital capacity ($1,038{\pm}620.41mL$) than the nonventilator group ($1,455{\pm}603.2mL$). Mean left ventricular ejection fraction and fractional shortening were greater in the home ventilator group, but the data did not show any statistical difference. The early ventricular filling velocity/late ventricular filling velocity ratio ($1.7{\pm}0.44$) was lower in the home ventilator group than in the nonventilator group ($2.02{\pm}0.62$. The mitral valve annular systolic velocity was higher in the home ventilator group (estimated ${\beta}$, 1.06; standard error, 0.48). Patients with Duchenne muscular dystrophy on a ventilator may have better systolic and diastolic cardiac functions. Conclusion: Noninvasive ventilator assistance can help preserve cardiac function. Therefore, early utilization of noninvasive ventilation or oxygen may positively influence cardiac function in patients with Duchenne muscular dystrophy.