• Biomedical Science Letters
• /
• v.7 no.2
• /
• pp.59-64
• /
• 2001

Nebulin is an unusually large actin-binding protein specific to the skeletal muscle of vertebrates. The correlation of nebulin size with thin filament length have led to the suggestion that nebulin acts as a molecular ruler for the length of thin filaments. An SH3 domain occupies the C terminus of nebulin, in the sarcomeric Z-disk and is preceded by a 120-residue stretch containing multiple putative phosphorylation sites. SH3 domain mediates protein-protein interaction involved in the subcellular localization of proteins, cytoskeletal organization and signal transduction. However the binding partner and physiological role of nebulin SH3 domains remains unknown. Using the yeast two-hybrid system, we identified supervillin, an actin-binding protein, as a nebulin SH3 domain-interacting protein. The SH3 domain of nebulin binds to the sequence encoding amino acids 977 to 1335 of supervillin. But the sequence encoding amino acids 977 to 1335 displays weaker binding than the sequence encoding amino acids 977 to 1788.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.40 no.5
• /
• pp.775-787
• /
• 2016

This study examined the wearing conditions of compression wear for weight training. Compression wear has recently received significant attention from the public and athletes as high-level functional sportswear. The survey was conducted on 373 men in their 20s for general information on purchase behavior, preferred brand, function, and preferred design. The majority of participants (n=181) were aware of the function of compression wear. The most selected reason for wearing compression wear was for its convenience during sports activities. Respondents had the greatest preference for designs with a round neckline, regular leggings type, upper arm-length sleeve, and thigh-length bottom. Respondents also wanted a stronger compression in the core muscle part (abdomen, back, and waist).

• Journal of Korean Biological Nursing Science
• /
• v.15 no.4
• /
• pp.193-201
• /
• 2013

Purpose: The purpose of the study was to evaluate the effect of the immediate postoperative nutritional status and calorie adequacy on clinical outcomes in liver transplant recipients. Methods: A total number of 99 patients who received liver transplants were recruited from a tertiary university hospital. Demography, subjective global assessment, clinical outcomes and calorie adequacy were evaluated through personal interviews, electronic medical records and dietary records. Anthropometric measures, body mass index and percent of ideal body weight were also obtained. Results: At admission to the Surgical Intensive Care Unit (SICU), the triceps skinfold thickness and mid-arm muscle circumference were significantly lower in the malnourished group than in the well-nourished group (p<.05, respectively). In the clinical outcomes, transfusion of red blood cells, mechanically ventilated hours, length of stay in the Intensive Care Unit (ICU), length of stay in the hospital, and prothrombin time were significantly higher in the malnourished group than in the well-nourished group (p<.05, respectively). The mechanically ventilated hour was significantly higher in the group with less than 50% of their required energy intake (p<.05). Conclusion: Therefore, it is important to assess the nutritional status of immediate postoperative patients. Furthermore, studies on nutritional interventions are urgently needed to provide adequate nutritional care for patients in ICUs.

• Journal of the Ergonomics Society of Korea
• /
• v.5 no.1
• /
• pp.3-9
• /
• 1986

This research is aimed at examining age-related changes of postural sway when people stand upright, examining external effects which can be exerted upon the postural sway (experiment 1), and also analyzing specific changing characters of posture-control by sudden impacts (experiment 2). The total number of subjects was 115, who are in twenties through seventies and 75 of them were participated in experiment 2. In experimen 1, the subjects were examined for 25 seconds respectively while standing upright with both feet and with eyes opened, standing upright with both feet and with eyes closed, and standing upright with a single foot and with eyes opened. In experiment 2, only while standing upright with both feet and with eyes opened they were examined for 5 seconds. Main findings were as follows: 1. In the single-foot standing position, the growing older exerted more important effects upon the fluctuation length and area of the center of gravity than in the both-foot standing position. 2. The standard deviation was increasing with age in the fluctuation length and the fluctuation area of the center of gravity. 3. There were no significant differences in daily variation, temperature change, and muscle burdening. 4. The recuperation from the postural sway by external impacts was so slow with age. 5. There were little differences in decrease frequencies among the subjects but younger persons.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
• /
• v.14 no.1
• /
• pp.10-15
• /
• 2003

Background and Objectives : Ankyloglossia, commonly known as tongue-tie, is the result of a short, fibrous lingual frenulum or highly attached geioglossus muscle. This condition may cause sucking and swallowing problems, articulation disorders, interference with the tongue's cleansing action, increased the potential for caries, and inability to lick the lips, play a wind instrument, and 'french kiss' Treatment is surgical procedure. In the most cases, horizontal sectioning and mucosal suture(the conventional procedure) is preferred, but in some cases, the Z-plastic procedure is effective. This study is aimed to compare the result of the two procedures. Materials and Methods : Twenty tongue-tie patients underwent operation. Ten patients were treated with the Z-plastic procedure and ten patients were treated with the conventional method randomly. We checked preoperative mobile tongue length, postoperative mobile tongue length, operation time and postoperative wound states. Results : Among the 20 cases of tongue-tie, 2 cases are excepted due to pre-operative state, thus we compared 18 cases of tongue-tie patients. There is no statistically significant difference between the two procedures except in operation time. The Z-plastic procedure apparently needs a little more operating time. Conclusion : Patients treated with the Z-plastic procedures appeared to have better outcomes, but the data shows no statistical significance except in operating time. Consequently, the Z-plastic procedure is indicated in a limited amount of cases.

• Journal of fish pathology
• /
• v.26 no.3
• /
• pp.295-301
• /
• 2013

Ferritin is an evolutionarily conserved protein that plays an important role in iron storage and detoxification. In this study, the gene encoding a ferritin H subunit homologue (RbFH) was cloned from rock bream (Oplegnathus fasciatus) and analyzed at the expression. The full-length ferritin H cDNA was 1162 bp long and contained an open reading frame (ORF) of 531 bp that encoded 177 amino acid residues with a predicted molecular mass of 20.8 kDa. The 5' UTR was 297 bp in length, and the 3' UTR 298 bp, and preceded by a 5'-untranslated region that contains a putative Iron Regulatory Element (IRE). The deduced amino acid sequence of RbFH shares extensive sequence identities with the H ferritins of a number of fish species and contains the ferroxidase center that is preserved in ferritin H subunits. Examination of tissue specific expression indicated that RbFH expression was most abundant in PBLs, RBC, liver and muscle.

• Journal of Veterinary Clinics
• /
• v.36 no.6
• /
• pp.301-305
• /
• 2019

Wii^® balance board (WBB, Nintendo, Japan) is a device that can measure and record the center of pressure path length (CPPL) and 95% confidence ellipse area (Area 95) in relation to body sway. For evaluating measure of improvement after reconstruction of medial patellar luxation (MPL) in small sized dogs, A total of 6 dogs with limping and lameness gait attributed to Grade II, III or IV MPL were evaluated. Dogs were measured for difference of extension and flexion range of motion in the stifle (dROM), muscle mass, lameness, willingness to bear weight on the affected limb while standing, and willingness to lift the contralateral limb scores, CPPL and Area 95 of WBB on pre-surgery, post-surgery 4, 8 weeks. CPPL was significantly different on pre-surgery compared with post-surgery 8 weeks (p < 0.05). Except for CPPL, measured variables were significantly different on pre-surgery compared with post-surgery 4 and post-surgery 8 weeks (p < 0.01).

• The Journal of the Society of Stroke on Korean Medicine
• /
• v.14 no.1
• /
• pp.8-14
• /
• 2013

■ Objectives The goal of this study is to find the correlation between the motor function and gait pattern of stroke patients. ■ Methods We measured Manual muscle test(MMT), Motricity index(MI) and Spatiotemporal gait parameters of admitted hemiplegic patients with stroke. The gait parameters were measured using a Treadmill gait system. ■ Results There is a significant correlation between motor function and spatiotemporal parameters such as step length, stride length, step time, stride time, total double support or cadence, in stroke patients. ■ Conclusion The better motor function of stroke was, the more gait improved.

• Animal Bioscience
• /
• v.36 no.9
• /
• pp.1393-1402
• /
• 2023

Objective: In this study effects of three types of beddings on broiler leg health and bone biomechanics were evaluated. Methods: A total of 504 male chicks (Ross 308) were randomly placed on three beddings (4 replicates/group; 42 birds/pen), zeolite-added litter (ZL), plastic-grid flooring (PF), and wood shavings (WS). On day 42, chickens were weighed, slaughtered, and samples (bone, muscle, and drumstick) were collected. Bones were subjected to leg health tests, morphometric measurements, biomechanical testing, and ash analysis. Results: Broilers in PF and WS groups showed higher live weight than the ZL group (p<0.001), and the incidence of tibial dyschondroplasia (TD) and varus valgus deformity due to distal bending was significantly higher in PF (p<0.001). Multinomial logistic regression showed that bedding has a significant (p = 0.038) contribution toward the development of TD. Tibial strength (p = 0.040), drumstick width (p = 0.001), and total femur and epiphyseal ash contents (p = 0.044, 0.016) were higher in the ZL group. Chicken live weight was correlated with tibial length and weight (r = 0.762, 0.725). Conclusion: Flooring and the type of bedding material directly affect broiler bone length, strength and leg health. Plastic bedding improves the slaughter weight of chickens on the expense of leg deformities, and zeolite litter improves leg health and bone strength.

• Physical Therapy Rehabilitation Science
• /
• v.12 no.2
• /
• pp.155-160
• /
• 2023

Objective: The purpose of this study is to confirm a comparison of bag weight and applied location change on plantar pressure and gait parameters (stride time, stride length, cadence) of the 20s students. Design: One group cross-sectional design Methods: The subjects were measured in each condition. Each condition was no carrying a bag, carrying a 3kg bag, and a 6kg bag on the right shoulder, and walked on the gait analyzer. After the location of the bag was changed, measured when a 3kg backpack and a 6kg backpack was each carried on the back while walking. Results: There was a statistically significant difference in plantar pressure according to bag weight when carried on the right shoulder (p<0.05). As a result of the post-hoc analysis, carrying a 6kg bag was a significant difference between no carrying a bag and carrying a 3kg bag (p<0.05). There was no statistically significant difference in changes in stride time, stride length, and cadence. There was no statistically significant difference in plantar pressure and gait parameters according to backpack weight. Conclusions: As a result of this study, it is thought that it will be possible to present a method for the application of the correct bag on location and weight in 20s students, and to prevent and reduce muscle musculoskeletal system diseases caused by incorrect bag wearing.