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The Heterochromatin Protein 1 (HP1) Family: Put Away a Bias toward HP1

  • Kwon, So Hee;Workman, Jerry L.
    • Molecules and Cells
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    • v.26 no.3
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    • pp.217-227
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    • 2008
  • Heterochromatin protein 1 (HP1) was first described in Drosophila melanogaster as a heterochromatin associated protein with dose-dependent effect on gene silencing. The HP1 family is evolutionarily highly conserved and there are multiple members within the same species. The multi-functionality of HP1 reflects its ability to interact with diverse nuclear proteins, ranging from histones and transcriptional co-repressors to cohesion and DNA replication factors. As its name suggests, HP1 is well-known as a silencing protein found at pericentromeres and telomeres. In contrast to previous views that heterochromatin is transcriptionally inactive; noncoding RNAs transcribed from heterochromatic DNA repeats regulates the assembly and function of heterochromatin ranging from fission yeast to animals. Moreover, more recent progress has shed light on the paradoxical properties of HP1 in the nucleus and has revealed, unexpectedly, its existence in the euchromatin. Therefore, HP1 proteins might participate in both transcription repression in heterochromatin and euchromatin.

Application of knowledge system through Ontology Technology in Next Generation Web (차세대 웹에서 온톨로지 기술을 통한 지식체계 적용)

  • Kim Min-Cheol
    • Journal of Korea Technology Innovation Society
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    • v.8 no.2
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    • pp.605-622
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    • 2005
  • Because, next generation web, semantic web consists of documents with semantic information, it enables computer interpret the contents of the documents, so that the information retrieval, interpretation and integration can be automated. The web documents with the semantic information may be made in ontology. In this paper, collaborative approach among the ontology design techniques is more excellent than the other techniques because it design the ontology through continuous evaluations and modification in terms of multiple views. So, we propose the process of designing and implementing the ontology for specific domain, which is Yeomigi tour place. Delphi technique, that is a kind of collaborative approach, is used when the ontology is designed.

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Local Area Management System Using WebCAM (WebCAM을 이용한 지역관리 시스템)

  • Ha, Geun-Hee;Kim, Do-Nyun;Cho, Dong-Sub
    • Proceedings of the KIEE Conference
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    • 1998.07g
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    • pp.2212-2214
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    • 1998
  • As there comes out better and better solutions for delivering multimedia data on the internet, the number of WebCAM sites which transmits pictures of any spot to the user's system is getting increased. WebCAM service over the internet can be compared with the CATV in that it is beyond the spatial constraints. In this project, we construct a WebCAM site which performs not only the fundamental WebCAM functions of capturing images and of transmitting them periodically but also various kinds of modules carrying out tasks such as image processing, remote control of the camera, processing multiple user requests, making panorama views and so on using Java which is the most popular language for the internet or CGI. The past images are stored in a database implemented for the WebCAM system, so the system can be extended to get over the constraints in time also.

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Pareto Optimal Design of the Vehicle Body (차체의 팔렛토 최적 설계)

  • Kim, Byoung-Gon;Chung, Tae-Jin;Lee, Jeong-Ick
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.17 no.4
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    • pp.67-74
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    • 2008
  • The important dynamic specifications in the aluminum automobile body design are the vibrations and crashworthiness in the views of ride comforts and safety. Thus, considerable effort has been invested into improving the performance of mechanical structures comprised of the interactive multiple sub-structures. Most mechanical structures are complex and are essentially multi-criteria optimization problems with objective functions retained as constraints. Each weight factor can be defined according to the effects and priorities among objective functions, and a feasible Pareto-optimal solution exists for the criteria-defined constraints. In this paper, a multi-criteria design based on the Pareto-optimal sensitivity is applied to the vibration qualities and crushing characteristics of front structure in the automobile body design. The vibration qualities include the idle, wheel unbalance and road shake. The crushing characteristic of front structure is the axial maximum peak load.

A Tangible Floating Display System for Interaction

  • Kim, Youngmin;Kang, Hoonjong;Ahn, Yangkeun;Choi, Kwang-Soon;Park, Byoungha;Hong, Sunghee;Jung, Kwang-Mo
    • Journal of the Optical Society of Korea
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    • v.18 no.1
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    • pp.32-36
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    • 2014
  • A tangible floating display that can provide different perspective views without special glasses being introduced. The proposed system can display perspective floating images in the space in front of the system with the help of concave mirrors. In order to avoid wearing special equipment to interact and deliver the sense of touch, the proposed system adopted an ultrasound focusing technology. For providing an immersive experience to the viewers, the proposed system consists of a tangible floating display system and a multiple-view imaging system for generating three lenticular displays in front of the users.

Congestion Control and Differentiated Services based Pricing (요금부과를 기반으로 구별되는 서비스와 혼잡관리)

  • 지선수
    • Journal of Korea Society of Industrial Information Systems
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    • v.8 no.4
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    • pp.17-25
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    • 2003
  • In the current bandwidth mechanism, ISPs provide guaranteed internet bandwidth within itself domains. Also transmission of data through the network can cause congestion. An inevitable consequence is partly responsible for the difficulties to ISPs and customers. In economic views, multiple demands for a scarce resource are mediated through a bandwidth market. Using the auction-based admission algorithm In price congestion, I propose a different pricing scheme for statistically guaranteed QoS.

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The Third Wave: Chinese Students' Values in Effective Mathematics Teaching in Two Secondary Schools

  • Zhang, Qiao-Ping
    • Research in Mathematical Education
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    • v.18 no.3
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    • pp.209-221
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    • 2014
  • In the last few decades there has been much interest in how mathematics can be effectively taught and learnt. The Third Wave is a unique ongoing international collaborative mathematics education research project, which aims to explore the relevant values of effective school mathematics teaching from both the teacher and student perspectives. As part of this project, this study investigates the related findings from students on the Chinese mainland. Multiple data were collected through classroom observations, focus group interviews, and written, open-ended questions. Twenty-four students from junior and senior secondary schools were invited to write down their views on an effective lesson, a good mathematics teacher, and how to do well in mathematics learning. Results showed that among the eight values determined in the study, the values of involvement, explanation, and examples were embraced by students across all grades. Students preferred teacher-led mathematics teaching. Junior secondary students placed more value on teachers' personalities, whereas senior students placed more value on teachers' teaching manners.

Performing Data Integration: Handed-code Approach vs. Tool-based Approach

  • Koo, Heung-Seo
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.7
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    • pp.39-44
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    • 2019
  • Data integration technology is one of the key elements in building data warehouses or big data, and is used to combine data from multiple sources and provide an integrated view to users. Traditionally, the performance of data integration uses a handed-code approach or a tool-based approach that utilizes data integration tools such as ETL. There is a debate about which methods are efficient. This study is conducted to give practitioners preparing for a data integration project an insight into how to perform data integration. This paper examines the views of experts on the controversy over the adoption of ETL tools that have been on the agenda of the data integration area for over a decade.

Landscape Design of Gyeong-In Ara Waterway (경인 아라뱃길 친수경관 기본설계)

  • An, Byung-Chul;Shin, Hyun-Don
    • Journal of the Korean Institute of Landscape Architecture
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    • v.38 no.2
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    • pp.119-129
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    • 2010
  • This study concerns the design strategy for the waterside of Gyeong-In Ara Waterway, Korea’s first constructed canal. This design focused on the creation of a new paradigm for waterway landscapes the major factors of which were geographical advantage, value of landscape and efficient approach. As the major space plan for the waterfront formed through the Gyeong-In Ara waterway from the Yellow Sea to the Han River, eight good views of the waterfront zone were designed by utilizing the waterway as a scenery viewpoint and, by constructing two traffic lanes for the scenic parkway connecting Incheon and the Gimpo terminal, both a linear greenway as well as various waterfront facilities were also designed. A boardwalk and bike path connecting the major theme parks were planned, and a waterfront pocket park was then organized based on the bike path. In this study, the result of the new waterfront result from the Gyeong-In Ara waterway was planned to have an identity as a new waterside culture space in order to achieve multiple functions including environmental, cultural, leisure, and tourism as well as management programs based on a variety of applied culture content and story-telling.

Partitioning and Constraints Generation for the Timing Consistency in the Hierarchical Design Method (계층적 설계 환경에서 일관된 타이밍 분석을 위한 분할 및 제한 조건 생성 기술 개발)

  • Han, Sang-Yong
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.1
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    • pp.215-223
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    • 2000
  • The advancements in technology which have lead to higher and higher levels of integration have required advancements in the methods used in designing VLSI chip. A key to enable a complicated chip design is the use of hierarchy in the design process. Hierarchy organizes the function of a large number of transistors ito a particular, easy-to-manage function. For these reasons, hierarchy has been used in the design process of digital functions for many years. However, there exists differences in a design analysis phase, especially in timing analysis, due to multiple views for the same design. In timing analysis of the hierarchical design, every path is analyzed within partitioned modules independently and the global timing analysis is applied to the whole design considering each module as a single timing component. Therefore, timing results of the hierarchical design could not be same as those of non-hierarchical flat design. In this paper, we formulate the timing problem in the hierarchical design and analyze the possible source of timing differences. We define a new terminology of "consistent result" between different views for the same design. We also propose a new partitioning algorithm to obtain the consistent results. This algorithm helps to enhance the design cycle time.

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