• YAKHAK HOEJI
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• v.37 no.3
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• pp.278-285
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• 1993

The anticlastogenic effect of N-acetylcysteine was tested in vivo in mouse bone-marrow micronucleus assay. The frequencies of micronuclei induced by adriamycin (5 mg/kg i.p.) in bonemarrow cells were decreased by the oral administration of N-acetylcysteine at 12 h before adriamycin injection. The observed suppressing effect was not a reflection of a delay in the formation of micronuclei by the cytotoxic effect of N-acetylcysteine. The anticlastogenic effects of SH compound including N-acetylcysteine, cysteine, cystine, S-carboxy methylcysteine and glutathione were also investigated by the multiple pretreatment. Each SH compound was administered orally every day for 5 days and adriamycin (5 mg/kg i.p.) was injected at 24h after the last dose of test compound. N-acetylcysteine and glutathione showed significantly the suppressive effect at dose of 10 and 25 mg/kg for N-acetylcysteine and at the dose of 25 mg/kg for glutathione. Our study suggests that N-acetylcysteine is capable of protecting the chromosomal damages in the normal cells during cancer chemotherapy by adriamycin, and may act as an anticlastogen against induction of micronuclei by superoxide generating agent such as adriamycin.

• Journal of The Korean Association For Science Education
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• v.25 no.1
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• pp.41-56
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• 2005

Assessing students' knowledge can be a challenging endeavor, as researchers attempt to capture the full complexity and potential development of children's ideas. In this study, the Dynamic Science Assessment (DSA) method (Magnusson, Templin, and Boyle, 1997) was employed to investigate 9-12 year old students' understandings of light, while engaging in multiple tasks with a flashlight with various reflectors and mirrors. The results showed that DSA was effective in providing an opportunity to establish a Zone of Proximal Development, in addition to diagnosing a student's prior understanding. Throughout the interview, a student showed a conceptual model of light as being a solid single entity whose shape can be determined by the shape of the casing of a flashlight. However, as DSA provided phenomena that could not be explained by his unitary model, the student began to re-examine his original conceptual model, and attempted to revise it. This study addressed how Dynamic Science Assessment can help us better understand, not only students' current state of understanding, but also a potential development of understanding in their ZPD. In that sense, this study argues that we should pay more attention to the instructive role of classroom assessment that can promote and support further development of students' deeper understandings.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.1243-1244
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• 2015

Finding solutions for the disabled is a major challenge for our society. In the case of a disability due to a malfunction of the nervous system, the origin may be accidental, genetic, or induced by environmental factors. This type of loss can cause loss or movement disorders (paraplegia, hemiplegia, quadriplegia, epilepsy, Parkinson's disease, multiple sclerosis, etc.) or malfunction of certain sensory functions (blindness, deafness, chronic pain, etc.). Many alternatives, more technology, have been imported to create interfaces between the human body and an artificial prosthesis in order to restore some functions of the human body. A wireless system, battery neurons probe was developed for one hand reading neural signals in the brain, and on the other hand also able to excite the neuron in the brain using a surface acoustic wave one ports (SAW) delay line reflection.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.314.2-314.2
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• 2014

To improve the optical and electrical properties of commercialized GaN-based light-emitting diodes (LEDs), many methods are suggested. In recent years, great efforts have been made to improve the internal quantum efficiency and light extraction efficiency (LEE) and promising approaches are suggested using a patterned sapphire substrate (PSS), V-pit embedded LED structures, and silica nanostructures. In this study, we report on the enhancement of photoluminescence (PL) intensity in GaN-based LED structures by using the combination of SiO2 (silica) nanospheres and polystyrene/SiO2 core-shell nanospheres. The SiO2 nanospheres-coated LED structure shows the slightly increased PL intensity. Moreover the polystyrene/SiO2 core-shell nanospheres-coated structure shows the more increase of PL intensity comparing to that of only SiO2 spheres-coated structure and the conventional structure without coating of nanospheres. The Finite-difference time-domain (FDTD) simulation results show corresponding result with experimentally observed results. The mechanism of enhancement of PL intensity using the coating of polystyrene/SiO2 core-shell nanospheres on LED surface can be explained by the improvement in extraction efficiency by both increasing the probability of light escape by reducing Fresnel reflection and by multiple scattering within the core-shell nanospheres.

• Journal of the Korean Society for Nondestructive Testing
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• v.15 no.1
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• pp.310-317
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• 1995

Crack detection technique by ultrasonics in structures and components made of austenitic stainless steel often loses its reliability due to the material characteristics during inservice inspection of nuclear power plants, especially in the area of detection and sizing in centrifugally cast stainless steel pipings. In order to understand and overcome this problem, computer program for tracing the ultrasonic rays within material has been developed to simulate the process of defect detection within weld. The program simulates through transmission and reflection technique in crack detection of austenitic stainless steel as well as ultrasonic beam propagation through multiple media including stainless steel cladding interface.

• Journal of the Korean Society for Precision Engineering
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• v.27 no.7
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• pp.63-70
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• 2010

We developed a new punching system that generates pinholes expressing texts or images on a plastic plate. The pin-holed plate is used as a new glamorous display board reflecting colorful lights from the light emitting diode (LED) installed on the edge side of the plate. The four degree-of-freedom punching system was designed to make same multiple holes on four plastic plates simultaneously. For this motion, we designed a structure for a simultaneous motion of the system. For even reflection of the lights from texts or images on the board and fast production of the pin-holed boards, fast motion including precise position control is very important. We also built a PC-based integrated control system including a GUI program to help users easily design luminous texts or images on the plastic plate. Also, we conducted a performance test of the system to verify the punching speed and position control of the pin holes on the plate.

• Proceedings of the Korea Water Resources Association Conference
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• 2004.05b
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• pp.557-562
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• 2004

A surface-piercing barrier model is presented for understanding morphological development in the sheltered region and investigating the main factors causing the severe accumulation. Surface-piercing structures like vertical barriers, surface docks and floating breakwaters are recently favored from the point of view of a marine scenario since they do not in general partition the natural sea. The numerical solutions are compared with experimental data on wave profiles and morphological change rates within a rectangular harbor of a constant depth protected by surface-piercing thin breakwaters as a simplified problem. Our numerical study involves several modules: 1) wave dynamics analyzed by a plane-wave approximation, 2) suspended sediment transport combined with sediment erosion-deposition model, and 3) concurrent morphological changes. Scattering waves are solved by using a plane wave method without inclusion of evanescent modes. Evanescent modes are only considered in predicting the reflection ratio against the vertical barrier and energy losses due to vortex shedding from the lower edge of plate are taken into account. A new relationship to relate the near-bed concentration to the depth-mean concentration is presented by analyzing the vertical structure of concentration. The numerical solutions were also compared with experimental data on morphological changes within a rectangular harbor of constant water depth. Through the numerical experiments, the vortex-induced flow appears to be not ignorable in predicting the morphological changes although the immersion depth of a plate is not deep.

• Journal of Korea Game Society
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• v.17 no.6
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• pp.199-208
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• 2017

Since the study by Turkle(1995), the concept of identity play in MMORPGs has been employed primarily to explain the reflection of users' identity in the avatar creation process in online games. This study attempts to conceptualize the identity play of the design process in which the user uses the avatar customizing system to create an avatar in the virtual world. This research verified the model of identity play through players' avatars, a model of the components of identity play constructed. The aims of this study pursued through an analysis of correlations of users' attitudes toward avatars. This study performed structural equation modeling to verify hypotheses about the variables that affect online identity play.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.2
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• pp.206-211
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• 2004

A new techique is proposed for suppressing sidelobes due to the wave reflected from the waveguide end in the traveling-wave slot array. In this approach we use multiple sections of reduced-height waveguide with the final section terminated with a short circuit instead of the conventional matched load. To show the validity of the proposed method, a Ku-band slotted waveguide is fabricated and tested. Measurements confirm the excellent sidelobe suppressing capability of the proposed method.

• Smart Structures and Systems
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• v.1 no.4
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• pp.385-404
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• 2005

The paper presents a model to calculate reinforcement strain using measured crack width in members under applied tension, flexure, and/or shear stress. Crack mapping using a new type of distributed coaxial cable sensors for health monitoring of large-scale civil engineering infrastructure was recently proposed and developed by the authors. This paper shows the results and performance of such sensors mounted on near surface of two flexural beams and a large scale reinforced concrete box girder that was subjected to cyclic combined shear and torsion. The main objectives of this health monitoring study was to correlate the sensor's response to strain in the member, and show that magnitude of the signal's reflection coefficient is related to increases in applied load, repeated cycles, cracking, and reinforcement yielding. The effect of multiple adjacent cracks, and signal loss was also investigated. The results shown in this paper are an important step in using the sensors for crack mapping and determining reinforcement strain for in-situ structures.