• Journal of Hydrogen and New Energy
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• v.17 no.2
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• pp.193-203
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• 2006

A high-speed and initial helium jet flow has been analyzed by a developed four-dimensional digital speckle tomography. Multiple high-speed cameras have been used to capture movements of speckles in multiple angles of view simultaneously because a shape of a nozzle for the jet flow is asymmetric and the initial jet flow is fast and unsteady. The speckle movements between no flow and helium jet flow from the asymmetric nozzle controlled by a solenoid valve have been obtained by a cross-correlation tracking method so that those distances can be transferred to deflection angles of laser rays for density gradients. The four-dimensional density fields for the high-speed helium jet flow have been reconstructed from the deflection angles by a developed real-time tomography method.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.31 no.3
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• pp.199-207
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• 2013

In hydrographic survey, data surveyed with multibeam system includes various errors due to multiple factors. These are corrected by a calibration called patch test, and if existing method is used, the test needs to be conducted for about 8 times for precise system calibration. For more prompt and precise multibeam system calibration, the exact offset of a ship was determined using terrestrial laser scanning and TS surveying, which was used as the initial input for the patch test. In the result, the error of closure was 0.001 m or less for TS surveying and backsight error was 0.005 m or less for scanning. All the surveying data based on the same local coordinate was converted into vessel reference coordinate during which R-square for all rotation angles was 0.99 or higher and standard deviation was 0.008 m or less. Finally, in a patch test using calculated offset of sensors and motion sensor offset, the offset of MBES transducer satisfied manual on hydrography only with 1-time calibration. With these results, it is thought that terrestrial laser scanning and TS surveying can fully be utilized for multibeam system calibration.

• Journal of Yeungnam Medical Science
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• v.29 no.2
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• pp.136-140
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• 2012

A 61-year-old male who complained of right upper quadrant pain was referred to the authors for evaluation after his computed tomography suggested biliary adenocarcinoma. The lesion consisted of multiple cysts with papillary mass and peri-ampullay mass. The patient underwent an operation due to a clinical suspicion of biliary cystadenocarcinoma, but the pathology confirmed biliary papillomatosis (BP) after diagnosing intrahepatic papillary neoplasm with high-grade dysplasia and invasive adenocarcinoma with papillary neoplasm from the distal common bile duct to the duodenum. BP is a disease characterized by multiple papillary masses. Its cause has yet to be discovered. It commonly manifests as bile duct dilation but rarely as a ductal cystic change. Under computed tomography or magnetic resonance imaging, both the BP and the cystic neoplasm can show bile duct dilation and a papillary mass, which makes their differential diagnosis difficult. A confirmative diagnosis can be made through a pathologic examination. BP is classified as a benign disease that can become malignant and may recur, though rarely. Its treatment of choice is surgical resection. Laser ablation or photodynamic therapy can be used for unresectable lesions. In the case featured in this paper, biliary papillomatosis was difficult to differentiate from cystic adenocarcinoma due to diffusely scattered multiple large cystic lesions in the liver, and it was histologically confirmed to have become malignant with cystic duct dilation after the operation. This case is reported herein with a literature review.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5371-5374
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• 2013

Objective: Photodynamic therapy (PDT) is an emerging therapeutic procedure suitable for the treatment of cervical cancer. However, the side effects of PDT are severe, including skin ulceration, so we designed an experiment to examine the effects of multiple low-dose photodynamic therapy of 5, 10, 15, 20-tetrakis(1-methylpyridinium-4-yl) porphyrin (Tmpyp4) on tumour growth by utilizing a model in nude mice implanted with Hela cervical cancer cells. Materials and Methods: Female BALB/c nude mice (aged 5-6 weeks, weighing 18-20 g) were used. Hela cervical cancer cells were injected subcutaneously ($1{\times}10^7cells/200{\mu}L$). Ten days after injection, the mice were divided into three groups (n=6), the A group of controls without any treatment, the B group receiving a single-treatment with Tmpyp4 (10 mg/kg, intratumor injection) and irradiation (blue laser, $108J/cm^2$), and the C group given three-treatments with Tmpyp4 (10 mg/kg, intratumor injection) and irradiation at intervals of two days. After starting treatment, tumours were measured every two days, to assess growth. At 2 weeks after the last treatment of C group, tumour tissue and organs were collected from each mouse to evaluate tumor histology and organ damage. Results: Tumour growth in C group was significantly inhibited compared with A and B groups (P<0.05), without any injury to the skin and internal organs. Conclusion: Our novel findings demonstrated that multiple low-dose photodynamic therapy of Tmpyp4 could inhibit cervical cancer growth significantly with no apparent side effects.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.54 no.1
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• pp.30-34
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• 2005

This study shows the lasing characteristics of InGaAs/InGaAsP multiple-quantum-well waveguide-type depleted optical thyristor (DOT) using the vertical window. The measured switching voltage and current are 3.36 V and 10 ㎂, respectively. The lasing threshold current is 131 mA at 25 ℃. The output peak wavelength is 1570 nm at a bias current of 1.22 Ith and there is not input signal anymore in the output port. The vertical injection depleted optical thyristor - laser diode (VIDOT-LD) using the vertical-injection structure shows very good isolation between input and output signal.

• Journal of the Optical Society of Korea
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• v.17 no.2
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• pp.205-212
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• 2013

Pain is one of the quite common symptoms in clinics and many treatment methods have been applied to relieve pain. Among the treatments, high-intensity light therapy for pain has been introduced, but this therapy has not been fully supported by confirmed efficacy due to the absence of quantitative assessments and treatment feedback data in real time. In this study, the evaluation of light distribution in tissue was performed with current high-intensity light sources quantitatively using light-tissue interaction simulations. The diffuse reflectance in tissue was generated using Monte Carlo simulation that traces photons as they undergo multiple scattering and absorption within each tissue layer (skin, fat, and muscle) and within multi-layered tissue. The results showed that the highest diffuse reflectance and the deepest penetration of tissue were achieved at ${\lambda}$=830 nm when compared with other wavelengths like ${\lambda}$=650 nm, 980 nm and 1064 nm.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1999.11b
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• pp.47-52
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• 1999

The visualization of Moire or laser-scanned data has been explored by many researchers and has been an important issue on computer graphics research. In this paper, we present various techniques that handle tremendous amount of 3D range data which are generated by the ETRI- Moire Scanner. The techniques include constructing an efficient data structure, constructing triangle meshes and decimation and registration of multiple-view range images and textures.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.1780-1781
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• 2011

There have been numerous studies on application of robots to in-pipe inspection system. In this thesis, a mobile robot that can move through elbows and vertical pipes having diameter 100mm is developed. Defect detection technology for locating wall-thinnings, corrosions and foreign materials is developed for high temperature and pressure pipings in thermal power plants, utilizing laser sensors installed on the robot. Actual defect detection performance is evaluated with application of the developed robot system to a mock-up pipings.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.12
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• pp.128-135
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• 2007

Micro-channels for a wave micropump have been fabricated using the Stereolithography and UV Photolithography. The micro-channel with a channel height of $500\;{\mu}m$ was fabricated with stereolithography. UV photolithography was used for producing micro-channels with a channel length less than $100\;{\mu}m$. The fabrication process data including spinning rpm, pre-bake and post-bake time, and develop time for single layer and multiple layer 3D micro-structures using SU-8 photo resist are experimentally found. A film mask printed with a 40,000 dpi laser printer was used for UV lithography and micro-structures in the order of tens of micrometers in dimension were successfully fabricated.

• Biomedical Science Letters
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• v.23 no.4
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• pp.395-401
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• 2017

Various preclinical and clinical trials have been conducted the efficacy of celastrol. In data presented in the current manuscript is the first trial to inhibit Helicobacter pylori with celastrol. In this study, the quantitative change of various H. pylori proteins including CagA and VacA by the anti-bacterial effect of celastrol was determined. The anti-H. pylori effects of celastrol was investigated by performing 2-dimensional electrophoresis and additional supporting experiments. After 2-dimensional electrophoresis analysis, spot intensities were analyzed and then each spot was identified using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF-MS) or peptide sequencing using Finnigan LCQ ion trap mass spectrometer (LC-MS/MS). The results show that celastrol has multiple effects on protein expression in H. pylori.