• Title/Summary/Keyword: multiple infections

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A Case of Flavobacterium indologenes Meningitis in Neonate (신생아의 Flavobacterium indologenes 뇌막염 1례)

  • Lee, Yeon-Ju;Kim, Jong-Hyun;Koh, Dae-Kyun;Kang, Jin-Han;Kim, Soo-Young;Yoon, Soo-Han
    • Pediatric Infection and Vaccine
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    • v.5 no.2
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    • pp.296-301
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    • 1998
  • Flavobacterium species are nonfastidious, oxidase-positive gram-negative rods that do not ferment glucose. These organism are widely distributed in nature and in hospital environments. In past, one of flavobacteria, Flavobacterium indologenes, was treated with non-pathogenic organism. Recently, several investigators have demonstrated the infection of this organism in human. Nowadays, the growth of F. indologenes in specimen should be considered a potential pathogen in infectious patients including neonate, especially in the setting of malignancy and with use of invasive procedures. The resistance of this organism to multiple antibiotics and the high incidence of polymicrobial bacteremia make it difficult to determine optimal therapeutic options. We experienced a case of neonatal bacterial meningitis causing by F. indologenes. So we report this case to evoke more concerns about the infections of this organism in human.

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Development of DNA Chip System for Differential Diagnosis of Porcine Enteric Pathogens

  • Kim, Tae-ju;Cho, Ho-seong;Kim, Yong-hwan;A.W.M. Effendy;Park, Nam-yong
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2003.10a
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    • pp.32-32
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    • 2003
  • Intestinal infections are common in growing pigs and can be caused by multiple pathogens, environmental and management factors [1]. Among the most important viruses in swine enteritis are porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis virus (TGEV), porcine enteric calicivirus (PECV), porcine group A rotavirus (PRV gp A) and bacteria are Escherichia coli and Salmonella spp. and protozoa is Isospora suis [1]. The DNA chip system can serve as a powerful tool that can be utilized for simultaneous detection of specific pathogenic bacteria strains and viruses [2,3]. The combination of PCR and DNA chip technology will provide a novel method for the detection of porcine enteric pathogens thus revolutionize the diagnosis and management of the disease. The aim of this study is to develop DNA chip system for the rapid and reliable detection of five major porcine enteric pathogens based on oligonucleotide DNA chip hybridization. (omitted)

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The intestinal parasite infection status of inhabitants in the Roxas city, the Philippines

  • Kim, Bong-Jin;Ock, Mee-Sun;Chung, Dong-Il;Yong, Tai-Soon;Lee, Kyu-Jae
    • Parasites, Hosts and Diseases
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    • v.41 no.2
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    • pp.113-115
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    • 2003
  • We carried out a small-scale survey to investigate the status of intestinal protozoa and helminthes infection of inhabitants in Roxas city, Mindoro, the Philippines. Total 301 stool samples were subjected to the formalin-ether concentration method for the detection of helminth ova and protozoan cysts. The overall positive rate was 64.5%, and that of male and female were 56.6% and 72.5%, respectively. The highest infected helminth was Ascaris lumbricoudes (51.2%), followed by Trichuris trichiura (27.6%), hookworm (8.0%) and Enterobius vermicularis (0.3%). The protozoa infection status revealed that Entamoeba coli was the most frequent (15.0%). lodoamoeba buetschlii and E. histolytica were found but few. The multiple infection more than two parasites was 29.6%, and double infection with A. lumbricoides and T. trichiura was most common. The intestinal helminth infections were highly prevalent in this area, according to this result, and we concluded that anthelminthic drugs should be given to inhabiiants, especially to children of 1 to 15 years-old.

Evolution of Genetic Polymorphisms of Plasmodium falciparum Merozoite Surface Protein (PfMSP) in Thailand

  • Kuesap, Jiraporn;Chaijaroenkul, Wanna;Ketprathum, Kanchanok;Tattiyapong, Puntanat;Na-Bangchang, Kesara
    • Parasites, Hosts and Diseases
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    • v.52 no.1
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    • pp.105-109
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    • 2014
  • Plasmodium falciparum malaria is a major public health problem in Thailand due to the emergence of multidrug resistance. The understanding of genetic diversity of malaria parasites is essential for developing effective drugs and vaccines. The genetic diversity of the merozoite surface protein-1 (PfMSP-1) and merozoite surface protein-2 (PfMSP-2) genes was investigated in a total of 145 P. falciparum isolates collected from Mae Sot District, Tak Province, Thailand during 3 different periods (1997-1999, 2005-2007, and 2009-2010). Analysis of genetic polymorphisms was performed to track the evolution of genetic change of P. falciparum using PCR. Both individual genes and their combination patterns showed marked genetic diversity during the 3 study periods. The results strongly support that P. falciparum isolates in Thailand are markedly diverse and patterns changed with time. These 2 polymorphic genes could be used as molecular markers to detect multiple clone infections and differentiate recrudescence from reinfection in P. falciparum isolates in Thailand.

Massive pneumothorax resulting from paragonimiasis (폐흡충증으로 인한 대량 기흉)

  • Lim, Woo Hee;Kim, Su Wan
    • Journal of Medicine and Life Science
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    • v.17 no.1
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    • pp.25-28
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    • 2020
  • The prevalence of pulmonary pargonimiasis in Korea has been steadily decreasing due to develop of the public health, and there have been few clinical cases of paragonimiasis infections, especially in pneumothorax. A 22-year-old man referred to emergency department for dyspnea and chest pain. The right lung was totally collapsed on a chest X-ray. We emergently performed a closed thoracostomy with a 28-Fr chest tube. However, the air leak from the chest tube persisted for three days after the closed thoracostomy. A chest computed tomography showed multiple subpleural consolidative nodular lesions and mixed ground-glass attenuation nodules. We potentially suspected a secondary pneumothorax resulting from pulmonary paragonimiasis infection because the patient was a Chinese man who was working at a Korean restaurant. We decided to perform a medical treatment instead of pulmonary wedge resections. The air leak was discontinued three days after the prescription of praziquantel. The patient was discharged nine days after the admission. We suggest that anti-parasitic drugs are very effective in the secondary pneumothorax resulting from paragonimiasis.

Influences of Perceived Behavior Control and Self-efficacy on Proper Hand Cleansing and Hand Washing Practices among Pre-practicum Nursing Students (임상실습 전 간호대학생의 올바른 손씻기와 실천에 대한 지각된 통제행위와 자기효능감의 영향)

  • Park, Kyung-Yeon
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.19 no.3
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    • pp.313-321
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    • 2012
  • Purpose: The purpose of the study was to investigate hand washing practice and proper hand cleansing among first and second year nursing students who are prone to be exposed to nosocomial infections, and to identify the influence of perceived behavior control and self-efficacy on hand washing practices and proper hand cleansing. Method: Data for 91 students were collected from a nursing college in a metropolitan city in Korea. Data were analyzed using descriptive, t-test, one way ANOVA, Pearson correlation coefficient, and multiple regression with SPSS/WIN 19.0. Result: The mean score for hand washing practice was 38.35 out of a possible score of 48, and the mean sore for proper hand cleansing was 18.63 out of a possible score of 28. The significant factors affecting student hand washing practice were 'residential type' (p=.016), 'perceived behavior control' (p=.021), and 'self-efficacy' (p=.033) which explained 19.9% of the variance. The significant factors affecting proper hand cleansing by the students were 'perceived behavior control' (p<.001) and 'regular exercise' (p=.026) which explained 29.8% of the variance. Conclusion: These results indicate a need for education programs on hand washing including strategies to improve perceived behavior control and self-efficacy to promote more effective hand washing practices.

A Case of Vernet's Syndrome Caused by Non-specific Focal Inflammation of the Neck (목의 비특이 국소염증에 의해 유발된 Vernet증후군 1예)

  • Ha, Sang-Wook;Kim, Jong Kuk;Kang, Sung-Jin;Kim, Min-Jeong;Yoo, Bong-Goo;Kim, Kwang-Soo;Lee, Ju-Ho
    • Annals of Clinical Neurophysiology
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    • v.9 no.2
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    • pp.81-84
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    • 2007
  • Vernet's syndrome is a complex of multiple cranial nerve palsy including ninth, tenth, and eleventh cranial nerves which results from various lesions involving the jugular foramen. There are several kinds of lesions that can cause Vernet's syndrome. It includes congenital cholesteatoma, vascular lesions such as protruded jugular bulb, infections such as external otitis or abscess, and tumoral lesions such as schwannoma or paraganglioma. We present a rare case of Vernet's syndrome caused by non-specific inflammatory mass lesion in the neck area sparing jugular foramen.

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Surgical Management of Aorto-Esophageal Fistula as a Late Complication after Graft Replacement for Acute Aortic Dissection

  • Lee, Jae-Hong;Na, Bubse;Hwang, Yoohwa;Kim, Yong Han;Park, In Kyu;Kim, Kyung-Hwan
    • Journal of Chest Surgery
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    • v.49 no.1
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    • pp.54-58
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    • 2016
  • A 49-year-old male presented with chills and a fever. Five years previously, he underwent ascending aorta and aortic arch replacement using the elephant trunk technique for DeBakey type 1 aortic dissection. The preoperative evaluation found an esophago-paraprosthetic fistula between the prosthetic graft and the esophagus. Multiple-stage surgery was performed with appropriate antibiotic and antifungal management. First, we performed esophageal exclusion and drainage of the perigraft abscess. Second, we removed the previous graft, debrided the abscess, and performed an in situ re-replacement of the ascending aorta, aortic arch, and proximal descending thoracic aorta, with separate replacement of the innominate artery, left common carotid artery, and extra-anatomical bypass of the left subclavian artery. Finally, staged esophageal reconstruction was performed via transthoracic anastomosis. The patient's postoperative course was unremarkable and the patient has done well without dietary problems or recurrent infections over one and a half years of follow-up.

Identification and Antimicrobial Susceptibility of Bacteria Isolated from Dogs with Chronic Otitis Externa

  • Park, Soyoung;Bae, Seulgi;Kim, Juntaek;Oh, Taeho
    • Journal of Veterinary Clinics
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    • v.34 no.1
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    • pp.23-26
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    • 2017
  • Otitis externa (OE) is an inflammatory disease of the externa auditory meatus that occurs commonly in dogs. Antimicrobial susceptibility tests should be performed in case of chronic OE for successful treatment. In this study, identification and antimicrobial susceptibility test of bacteria isolated from dogs with chronic OE was performed. From 60 dogs with chronic OE, 60 bacterial species were identified. The most frequently identified species were Staphylococcus spp. (51%), followed by Pseudomonas spp. (15%) and Enterococcus spp. (14%). A single bacterial infection and multiple bacterial infections were observed in 67.5% and 32.5%, respectively. Staphylococcus spp. was susceptible to imipenum. Pseudomonas spp. was found to be susceptible to amikacin, cefepime, imipenum and piperacillin-tazobactam. Enterococcus spp. was susceptible to ampicillin-sulbactam, imipenum and piperacillin-tazobactam. Imipenum was highly susceptible antibiotic against both Gram-positive and negative bacteria whereas aztreonam and vancomycin were highly resistant. These results could suggest the optimal choice of antimicrobial agents for canine OE treatment.

Factors Influencing the Infection Control Performance of Catheter-Associated Urinary Tract Infection of Nurses in Hospitals (중소병원 간호사의 유치도뇨관 관련 요로감염 감염관리 수행 영향 요인)

  • Choi, Eun Yeong;Song, Min Sun
    • Journal of Korean Clinical Nursing Research
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    • v.25 no.3
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    • pp.303-313
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    • 2019
  • Purpose: The purpose of this study was to examine nurses' knowledge, health beliefs, and performance regarding the infection control of catheter-associated urinary tract infection (CAUTI) and to identify factors affecting their infection control performance of the CAUTI. Methods: The subjects were 166 nurses at three hospitals with less than 300 beds in urban areas.Data were collected using structured questionnaires about knowledge, health beliefs, and performance regarding the infection control of the CAUTI. Statistical analysis included t-test, ANOVA, Pearson's Correlation Coefficients, Multiple regression analysis. Results: The factors affecting the infection control performance of CAUTI were knowledge (β=.18, p=.010), perceived seriousness (β=.25, p=.001), perceived barriers (β=.41, p<.001), and cues to action (β=.15, p=.030), and these factors explained 28.7% of the variance for the infection control performance of the CAUTI. Conclusion: In this study, higher levels of knowledge, perceived seriousness and, cues to action, and lower perceived barriers resulted in a corresponding higher performance in the infection control of CAUTI. Based on these findings, providing intervention programs enhancing the health beliefs of nurses is necessary to ensure their infection control performance of the CAUTI.