• Journal of the Korean Geographical Society
• /
• v.38 no.3
• /
• pp.389-399
• /
• 2003

CRN (Cosmogenic radionuclide) methodology has been a versatile tool applicable to a wide range of geomorphology. This study was underiaken to ascertain the rate of erosion and exposure age of mountain-top detritus (tors and block streams) on Mt. Maneo by employing the concentrations of in-situ produced cosmogenic $^{10}$ Be and $^{26}$ Al from bedrock surfaces that are exposed to cosmic rays. The results suggest that tors on the summit were positioned here during the glacial period but no later than 65ka and block streams have been stabilized also since the last glacial period but no later than 38ka. The tors on the summit have been eroded at a slower rate (9m/Ma) than blocks on the hillslope (15m/Ma) since the initial abrupt exposure of each landform to cosmic rays, suggesting that there is a slight difference in the rate of erosion between the summit and the hillslope, and that the local relief between the two areas has been increased. When the $^{26}$ Al/$^{10}$ Be-$^{10}$ Be concentrations from samples are plotted in Lal's steady-state erosion island, one sample (from a for) has complex exposure histories, which can be explained by the occurrence of multiple chipping event of 5cm to 60cm in length on the surface of the rock.

• Journal of The Korean Association For Science Education
• /
• v.33 no.1
• /
• pp.161-180
• /
• 2013

The purpose of this paper is to introduce the current studies and research methods about Learning Progressions disseminated to several countries including the U.S. since 2006. It also provides a methodological base to investigate learning progressions in science by introducing a case study of learning progression conducted in Korea. For this study, we described several features of current studies on learning progressions in the U.S., and reported the common ways and sequences employed in examining learning progressions especially with respect to assessment for learning. Learning progressions are descriptions of developmental pathways of learning a topic, in which science knowledge is used in students' engaging in science practices. Each learning progression consists of upper anchor, lower anchor, and intermediate steps that connect both anchors. In investigating a learning progression, researchers usually utilize Wilson's four building blocks of assessment system based on the assessment triangle. This kind of method was also applied in investigating the learning progression for water cycle in this study. We discussed implication and consideration for the future research on learning progressions in science in Korea.

• Journal of Korea Multimedia Society
• /
• v.7 no.8
• /
• pp.1183-1194
• /
• 2004

Network partitioning problem is to partition a network into multiple blocks such that the size of cutset is minimized while keeping the block sizes balanced. Among these, iterative algorithms are regarded as simple and efficient which are based on cell move of Fiduccia and Mattheyses algorithm, Sanchis algorithm, or Kernighan and Lin algorithm. All these algorithms stipulate balanced block size as a constraint that should be satisfied, which makes a cell movement be inefficient. Park and Park introduced a balancing coefficient R by which the block size balance is considered as a part of partitioning cost, not as a constraint. However, Park and Park's algorithm has a square time complexity with respect to the number of cells. In this paper, we proposed Bucket algorithm that has a linear time complexity with respect to the number of cells, while taking advantage of the balancing coefficient. Reducing time complexity is made possible by a simple observation that balancing cost does not vary so much when a cell moves. Bucket data structure is used to maintain partitioning cost efficiently. Experimental results for MCNC test sets show that cutset size of proposed algorithm is 63.33% 92.38% of that of Sanchis algorithm while our algorithm satisfies predefined balancing constraints and acceptable execution time.

• The Korean Journal of Physiology and Pharmacology
• /
• v.12 no.2
• /
• pp.83-87
• /
• 2008

The fyn-related kinase (FRK) belongs to the tyrosine kinase family of protein kinases. Recent studies have shown that Frk affects pancreatic beta cell number during embryogenesis and promotes beta cell cytotoxic signals in response to streptozotocin. To investigate the genetic association between FRK polymorphisms and the risk of obesity in Korean population, single nucleotide polymorphisms (SNPs) in the FRK gene region were selected and analyzed. The body mass index (BMI) was calculated, and biochemical data (systolic blood pressure, diastolic blood pressure, hemoglobin A1C, triglyceride, total cholesterol, high density lipoprotein, and low density lipoprotein) of blood sample from each subject were also measured. One hundred fifty five healthy control and 204 overweight/obesity subjects were recruited. Genotype frequencies of six SNPs [rs6568920 (+8391G>A), rs3756772 (+56780A>G), rs3798234 (+75687C>T), rs9384970 (+68506G>A), rs1933739 (+72978G>A), and rs9400883 (+75809A>G)] in the FRK gene were determined by Affymetrix Targeted Genotyping Chip data. According to the classification of Korean Society for the Study of Obesity, control (BMI 18 to < 23) and overweight/obesity (BMI$\geq$23) subjects were recruited. For the analysis of genetic data, EM algorithm, SNPStats, Haploview, HapAnalyzer, SNPAnalyzer, and Helixtree programs were used. Multiple logistic regression analysis (codominant, dominant, and recessive models) was performed. Age and gender as covariates were adjusted. For biochemical data, Student's t test was used. The mean value of BMI in the control and overweigh/obesity groups was 21.1${\pm}$1.2 (mean${\pm}$SD) and 25.6${\pm}$2.0, respectively. All biochemical data of the overweight/obesity group were statistically significance, compared with the control group. Among six SNPs, two linkage disequilibrium (LD) blocks were discovered. One block consisted of rs1933739 and rs9400883, and the other comprised rs3756772 and rs3798234. One SNP (rs9384970, +68506G>A) showed an association with overweight/obesity in the codominant model (p=0.03). Interestingly, the AA genotype distribution in the overweight/obesity group (n=7, 3.5%) was higher than those in the control group (n=1, 0.6%), which is not found in either Japanese or Chinese subjects. Therefore, the AA genotype of rs9384970 may be a risk factor for development of obesity in Korean population. The results suggest that FRK may be associated with overweight/obesity in Korean population.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.50 no.7
• /
• pp.102-108
• /
• 2013

In manufacturing of solution-processed organic electronic devices, a spin coating method is frequently used, but which has a big problem. Solvent in a solution has a decisive effect such as physical and chemical damage for successive solution-based film deposition. Such a severe damage by solvent restricts for fabricating building blocks of multi-layered films from solutions. In this work, it will be shown that a proper combination of well-known solvents gives a chance to fabricate multi-layered film, also this new method was applied to make organic field effect transistor. Two types of bottom gate, bottom contact transistors were fabricated, one of which is fabricated by conventional single spin coating method, the other fabricated by double spin coating method. Compared with the electrical characteristics in a single spin coated transistor, the leakage current between source and gate electrode was decreased, ON state current was increased, and the extracted saturation mobility was multiplied more than 2.7 time for double spin coated transistors. It is suggested that the multiple coated gate dielectric structure is more desirable for high performance organic ferroelectric field effect transistors.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.51 no.10
• /
• pp.96-106
• /
• 2014

Previous academic research on FPGA tools has relied on simple imaginary models for the targeting architecture. As the first step to overcome such restriction, the issues on analytic placement and legalization which are applied to commercial FPGAs have been brought up, and several techniques to remedy them are presented, and evaluated. First of all, the center of gravity of the placed cells may be far displaced from the center of the chip during analytic placement. A function is proposed to be added to the objective function for minimizing this displacement. And then, the density map is expanded into multiple layers to accurately calculate the density distribution for each of the cell types. Early fixation is also proposed for the memory blocks which can be placed at limited sites in small numbers. Since two flip-flops share control pins in a slice, a compatibility constraint is introduced during legalization. Pre-packing compatible flip-flops is proposed as a proactive step. The proposed techniques are implemented on the K-FPGA fabric evaluation framework in which commercial architectures can be precisely modeled, and modified for enhancement, and validated on twelve industrial strength examples. The placement results show that the proposed techniques have reduced the wire length by 22%, and the slice usage by 5% on average. This research is expected to be a development basis of the optimization CAD tools for new as well as the state-of-the-art FPGA architectures.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.26 no.3
• /
• pp.311-322
• /
• 2010

The purpose of this study was to evaluate the bond strengths between IPS e.max Press and four different types of resin cements that often used for esthetic restoration. Disc shaped IPS e.max Press blocks(N=40, diameter: 12mm, thickness: 3mm) were fabricated according to the manufacture's instruction and cleaned with ultrasonic cleaner. They were embedded into an autopolymerizing acrylic resin. Fourty cylinder shaped resin block(Filtek Z350, diameter: 4.5mm, thickness: 3mm) were fabricated using a plastic tube. Each specimens were randomly divided into 4 experimental group and bonded each other using 4 different resin cements(Variolink II(light-cure), Variolink II(dual-cure), Calibra, Super-Bond C&B) according to the manufactures' recommendations. All the specimens were stored in normal saline at $37^{\circ}C$ for 24 hours before test. Universal testing machine at a crosshead speed of 1mm/min was used to evaluate the shear bond strength. The data were statistically analyzed using one-way ANOVA(P<.01). Multiple comparison was done by the Tukey HSD test. The shear bond strength of Super-Bond C&B to e.max was significantly lower than those of Calibra, Variolink II(light-cure), Variolink II(dual-cure) (P<.01). The shear bond strength of Calibra, Variolink II(light-cure), Variolink II(dual-cure) to e.max were not significantly different. The shear bond strengths of light-cure/dual-cure cement were higher than that of self-cure cement.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.45 no.4
• /
• pp.41-49
• /
• 2008

H.264/AVC supports variable block motion compensation, multiple reference images, 1/4-pixel motion vector accuracy, and in-loop deblocking filter, compared with the existing compression technologies. While these coding technologies are major functions of compression rate improvement, they lead to high complexity at the same time. For the H.264 video coding technology to be actually applied on low-end / low-bit rates terminals more extensively, it is essential to improve tile coding speed. Currently the deblocking filter that can improve the moving picture's subjective image quality to a certain degree is used on low-end terminals to a limited extent due to computational complexity. In this paper, a performance improvement method of the deblocking filter that efficiently reduces the blocking artifacts occurred during the compression of low-bit rates digital motion pictures is suggested. In the method proposed in this paper, the image's spatial correlational characteristics are extracted by using the variable block information of motion compensation; the filtering is divided into 4 modes according to the characteristics, and adaptive filtering is executed in the divided regions. The proposed deblocking method reduces the blocking artifacts, prevents excessive blurring effects, and improves the performance about $30{\sim}40%$ compared with the existing method.

• Journal of KIISE:Computer Systems and Theory
• /
• v.33 no.9
• /
• pp.592-607
• /
• 2006

This paper proposes a technique to select processors and hardware IPs and to map the tasks into the selected processing elements, aming to achieve high performance with minimal system cost when multitask applications with real-time constraints are run on a multicore SoC. Such technique is called to 'Hardware-Software Cosynthesis Technique'. A cosynthesis technique was already presented in our early work [1] where we divide the complex cosynthesis problem into three subproblems and conquer each subproblem separately: selection of appropriate processing components, mapping and scheduling of function blocks to the selected processing component, and schedulability analysis. Despite good features, our previous technique has a serious limitation that a task monopolizes the entire system resource to get the minimum schedule length. But in general we may obtain higher performance in multitask multicore system if independent multiple tasks are running concurrently on different processor cores. In this paper, we present two mapping techniques, task mapping avoidance technique(TMA) and task mapping pinning technique(TMP), which are applicable for general cases with diverse operating policies in a multicore environment. We could obtain significant performance improvement for a multimedia real-time application, multi-channel Digital Video Recorder system and for randomly generated multitask graphs obtained from the related works.

• Korean Journal of Clinical Laboratory Science
• /
• v.39 no.2
• /
• pp.128-135
• /
• 2007

This study was designed to investigate the correlation between the expression rate of p53 and p21 proteins by immunohistochemical staining and tumor prognostic factors including the tumor size, histological differentiation and Dukes' stage of tumor prognostic factors in colon cancer, and to acquire necessary data for the presumption of diagnosis, treatment and prognosis of colon cancer patients. From January 2000 to January 2003 at Hanyang University Guri Hospital, the paraffin blocks of 35 patients diagnosed with colon cancer whose pathologic reports were possible to review were selected. Harris hematoxylin & eosin (H&E) staining and immunohistochemical staining by ABC (Avidin Biotin Conjugate) method were performed. The histological differentiation grade and stage were classified according to the classification of the World Health Organization (WHO) and modified Dukes's stage from H&E staining. The expression rate of p53 and p21 proteins were analyzed by immunohistochemical staining. The results was analyzed statistically by SPSS (Windows version 8.0). As a result, the expression rate of p53 protein was 11.4% (4 cases) in clear differentiation, 48.6% (17 cases) in moderate differentiation, and 17.1% (6 cases) in poor differentiation. In other words, the poorer the differentiation, the higher the expression rate of p53 protein (p<0.05). The expression rate of p21 was 17.1% (6 cases) in clear differentiation, 40.0%(14 cases) in moderate differentiation, and 8.6% (3 cases) in poor differentiation, According to the progression of histological malignant degeneration, the expression rate of p21 protein decreased distinctively (p<0.05). However, the correlation between the two above mentioned proteins and the tumor-size and Dukes' stage was not of statistical significance. In the comparison of the expression rate of p53 protein with that of p21 protein, in 10 cases, p53 protein expression was positive while p21 protein expression was negative, and in 6 cases, p53 protein expression was negative whereas p21 protein expression was positive. Consequently a statistically significant inverse correlation between the expression rate of p53 protein and that of p21 protein was observed (p<0.05). In conclusion, we found a significant correlation between histological differentiation and the expression rate of p53 and p21 proteins (p<0.05), and a significant inverse correlation between the expression rate of p53 protein and that of p21 protein (p<0.05). Also, it could be confirmed that the over expression of p53 and p21 proteins is closely associated with the occurrence of colon cancer and its progress. Therefore, it is thought that this study may be greatly beneficial to the presumption of diagnosis, treatment and prognosis of colon cancer patients.