• Title/Summary/Keyword: multi-resistance

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A Study on the Characteristics of Giant Magneto Resistance using Multi Layers (다층막을 이용한 거대자기저항(GMR)의 특성 연구)

  • Kim, Byeong-Woo;Lee, Young-Seok
    • Transactions of the Korean Society of Automotive Engineers
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    • v.16 no.5
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    • pp.113-118
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    • 2008
  • We have developed an integrated giant magneto resistance using not only circuit but also integrating technique with semiconductor for automobile application. It has four elements used for giant magneto resistance sensor. Ni-Fe/Cu multi layers were prepared on a glass substrate by magnetron sputtering. The dependence of magneto resistance on the thickness of the Ni-Fe and Cu layers was investigated. The MR ratio showed a saturated a peak at Cu layer $10{\AA}$, Ni-Fe layer $50{\AA}$, where the MR ratio is about 8.7% at room temperature. By means of Ni-Fe multi film and specific integrating technique, these new giant magneto resistance sensor showed excellent resistance characteristics.

H2O2 Generating Ability and Multi-Drug Resistance of Lactic Acid Bacteria Required for Long-Term Inpatient Treatment with Antibiotic Resistance

  • Yuk, Young Sam
    • International journal of advanced smart convergence
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    • v.11 no.4
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    • pp.227-239
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    • 2022
  • Purpose: In our study, in order to find lactic acid bacteria (LAB) with multi-drug resistance to antibiotics, we isolated 140 strains from 15 types of kimchi commercially available in Korea and 20 types of Kimchi made at home from January to December in 2016, and investigated their H2O2 generating ability and multi-drug resistance to antibiotics. Methods: In order to observe the H2O2 generation ability of LAB, we performed the experiment with methods such as Rabe, Hillier, and Kang. To test the antibacterial susceptibility of LAB, we used the disc agar diffusion method using MRS agar (Difco, USA) according to the CLSI and WHO test methods. There are 18 types of antibiotic discs used. Results: Out of the total numbers of 140 strains, 6 strains of Ent. Faecium, 25 strains of L. plantarum, 1 strain of L. rhamnosus, 3 strains of L. sakei, 1 strain of L. acidophilus, 1 strains St. thermophilus, and 7 of unidentified strains generated H2O2. The antibiotic susceptibility of Ent. Faecium indicated SXT, OX, NA, and E; and the antibiotic susceptibility of L. plantarum indicated NA; and the antibiotic susceptibility of St. thermophilus indicated NA, CC, RA, CTT, CM, and P ; and the antibiotic susceptibility of L. rhamnosus indicated SXT, VA, NA and CTT; and the antibiotic susceptibility of 6 strains of L. sakei indicated SXT, OX, NOR, NA, CTT and CIP, all indicating antibiotic resistance. In the case of multi-drug resistance to antibiotics for 53 strains of L. antarum, 8-drug resistance was the most common with 25 strains, followed by 7-drug-resistant strains with 18 strains, 9-drug-resistant strains with 4 strains, 6-drug-resistant strains with 3 strains, 5-drug-resistant strains with 2 strains, and 17-drug-resistant strains with 1 strain. In the case of multi-drug resistance to antibiotics for Ent. Faecium 27 strains, 9-drug resistance was most commonly identified as 9 strains, 8-drug resistance was identified as 6 strains, 7- and 11 drug resistances were identified as 4 strains each, and 4- and 6-drug resistances were identified as 1 strain each. Conclusion: Ent. Faecium, L. plantarum, L. rhamnosus, L. sakei, and St. thermophilus, shown to have anantibacterial activity in previous studies on LAB and shown to have and H2O2 generating ability, antibiotic resistance and multi-drug resistance in this study, are expected to be able to play an excellent role for long-term inpatients to use as an alternative to antibiotics and to cope with emerging antibiotic resistance.

The effects of Clothing Materials and Multi-layered Textiles on Thermal Resistance Value (보온력에 미치는 피복재료와 겹침의 영향)

  • 손원교;차옥선
    • Journal of the Korean Home Economics Association
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    • v.37 no.11
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    • pp.157-165
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    • 1999
  • This study was carried out to examine the effect of clothing materials and multi-layered textiles on thermal resistance value. Cotton, polyester, wool, silk, rayon and acetate were selected for the specimens. Thermal resistance value was tested with 2 kinds of methods(thermo labo II and BK type tester). The results were as follows; 1. The effects of clothing materials for thermal resistance value were decreased by adding layers. 2. When the fabrics are measured with multiple layers, the fabric of the lowest thermal resistance value at single layer was showed the highest increasing tendency for all test methods.

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Estimation of Heat Generation in Multi-Contact Connector for Superconducting Magnet Application (초전도자석 시스템 응용을 위한 멀티-컨텍 커넥터의 열 발생 특성 평가)

  • Kim, M.S.;Choi, Y.S.;Kim, D.L.;Lee, Y.A.
    • Progress in Superconductivity
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    • v.14 no.2
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    • pp.122-127
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    • 2012
  • Current leads are one of the important components for carrying the current to the coil in the superconducting magnet system. Heat leakage through the current lead is the major factor of entire heat load in the cryogenic system because current leads carry the current from room temperature to near 4 K, connecting thermally each other. Therefore, minimization heat load through current lead can reduce the operating temperature of superconducting magnet. The semi-retractable current lead, composed of multi-contact connector and HTS element, is one of good options. Comprehension of Multi-contact connector's structure, contact resistance and heat generation is essential for estimating heat generation in current leads. Multi-contact connector has several louvers inside of socket and the shape, number, size of louvers are different with the size of connector. Therefore contact area, current path and contact resistance are also different. In this study, the contact resistance in multi-contact connector is measured using the electrical power as a function of connector's size and temperature. Also, the unique correlation of electrical contact resistance is derived and heat generation is estimated for superconducting magnet application.

Effects of Vinorelbine on Cisplatin Resistance Reversal in Human Lung Cancer A549/DDP Cells

  • Zhou, Yu-Ting;Li, Kun;Tian, Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4635-4639
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    • 2013
  • Multi-drug resistance (MDR) is an essential aspect of human lung cancer chemotherapy failure. Recent studies have shown that vinorelbine is involved in underlying processes in human tumors, reversing the MDR inseveral types of cancer cells. However, the roles and potential mechanism are not fully clear. In this study, we explored effects of vinorelbine in multi-drug resistance reversal of human lung cancer A549/DDP cells. We found that vinorelbine increased drug sensitivity to cisplatin and intracellular accumulation of rhodamine-123, while decreasing expression of P-glycoprotein (P-gp), multi-drug resistance-associated protein (MRP1) and glutathione-S-transferase ${\pi}$ (GST-${\pi}$) in A549/DDP cells. At the same time, we also established downregulation of p-Akt and decreased transcriptional activation of NF-${\kappa}B$ and twist after vinorelbine treatment. The results indicated that vinorelbine might be used as a potential therapeutic strategy in human lung cancer.

Resistance of concrete made with air- and water-cooled slag exposed to multi-deterioration environments (서냉 및 급냉슬래그를 적용한 콘크리트의 복합열화 저항성)

  • Lee, Seung-Tae;Park, Kwang-Pil;Park, Jung-Hee;Park, Se-Ho
    • International Journal of Highway Engineering
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    • v.20 no.3
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    • pp.11-18
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    • 2018
  • PURPOSES : Durability of concrete is traditionally based on evaluating the effect of a single deterioration mechanism such as freezing & thawing action, chloride attack, carbonation and chemical attack. In reality, however, concrete structures are subjected to varying environmental exposure conditions which often results in multi-deterioration mechanism occurring. This study presents the experimental results on the durability of concrete incorporating air-cooled slag(AS) and/or water-cooled slag(WS) exposed to multi-deterioration environments of chloride attack and freezing & thawing action. METHODS : In order to evaluate durable performance of concretes exposed to single- and multi-deterioration, relative dynamic modulus of elasticity, mass ratio and compressive strength measurements were performed. RESULTS :It was observed that multi-deterioration severely affected durability of concrete compared with single deterioration irrespective of concrete types. Additionally, the replacement of cement by AS and WS showed a beneficial effect on enhancement of concrete durability. CONCLUSIONS : It is concluded that resistance to single- and/or multi-deterioration of concrete is highly dependent on the types of binder used in the concrete. Showing the a good resistance to multi-deterioration with concrete incorporating AS, it is also concluded that the AS possibly is an option for concrete materials, especially under severe environments.

3-D Numerical Experiment for Estimation of Equivalent Resistance Coefficient due to Multi-piers : Effect of Transverse Intervals (상당저항계수식 산정을 위한 3차원 수치실험 : 횡방향 이격거리의 영향)

  • Kim, Hyeong-Seok;Choi, Jun-Woo;Ko, Kwang-Oh;Yoon, Sung-Bum
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.21 no.3
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    • pp.216-223
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    • 2009
  • A transverse drag interaction coefficient of the equivalent resistance coefficient formula for square multi-piers higher than water depth and arranged with equal intervals was studied. From the assumption that the energy loss due to drag interaction according to transverse intervals of resistance bodies is essentially identical to the energy loss due to thick orifice according to porosities, the transverse drag interaction coefficient was derived by employing the orifice's energy loss coefficient. The equivalent resistance coefficient formula including the drag interaction coefficient was compared with the numerical experiments using FLOW-3D, the performance of which was verified by Kim et al.(2008) in the experimental condition with the multi-piers. The comparisons showed good agreement and thus, the equivalent resistance coefficient formula, which does not only consider frictional resistance but also consider the multi-piers' drag resistance varied according to the intervals in longitudinal or transverse direction, was verified.

The Diversity of Multi-drug Resistance Profiles in Tetracycline-Resistant Vibrio Species Isolated from Coastal Sediments and Seawater

  • Neela Farzana Ashrafi;Nonaka Lisa;Suzuki Satoru
    • Journal of Microbiology
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    • v.45 no.1
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    • pp.64-68
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    • 2007
  • In this study we examined the multi-drug resistance profiles of the tetracycline (TC) resistant genus Vibrio to determine its susceptibility to two ${\beta}-lactams$, ampicillin (ABPC), and mecillinam (MPC), as well as to macrolide, erythromycin (EM). The results showed various patterns of resistance among strains that were isolated from very close geographical areas during the same year, suggesting diverse patterns of drug resistance in environmental bacteria from this area. In addition, the cross-resistance patterns suggested that the resistance determinants among Vibrio spp. are acquired differently within the sediment and seawater environments.

Simulating the Response of a 10-Storey Steel-Framed Building under Spreading Multi-Compartment Fires

  • Jiang, Jian;Zhang, Chao
    • International Journal of High-Rise Buildings
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    • v.7 no.4
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    • pp.389-396
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    • 2018
  • This paper presents a numerical investigation on the structural response of a multi-story building subjected to spreading multi-compartment fires. A recently proposed simple fire model has been used to simulate two spreading multi-compartment fire scenarios in a 10-story steel-framed office building. By assuming simple temperature rising and distribution profiles in the fire exposed structural components (steel beams, steel column and concrete slabs), finite element simulations using a three-dimensional structural model has been carried out to study the failure behavior of the whole structure in two multi-compartment fire conditions and also in a standard fire condition. The structure survived the standard fire but failed in the multi-compartment fire. Whilst more accurate fire models and heat transfer models are needed to better predict the behaviors of structures in realistic fires, the current study based on very simple models has demonstrated the importance and necessity of considering spreadingmulti-compartment fires in fire resistance design of multi-story buildings.

Measurement of Resistance of Multi-Grounded System by Ground Current Measurement (접지전류 측정에 의한 다중 접지계통의 접지저항 측정)

  • 최종기;안용호;정길조;한병성;김경철
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.53 no.4
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    • pp.234-237
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    • 2004
  • Measuring ground resistance has been a popular method of evaluation of the grounding electrode performance. If some portions of grounding electrodes are lost by corrosion, aging or other reasons, consequent deteriotation of the grounding performance would be resulted. It is one of the reasons why it is required to evaluate the performance of grounding systems regularly. However, in case of the electric facilities with multi-grounded system such as power substations with multi-grounded overhead ground wires and/or distribution line neutrals, it is practically difficult to disconnect neutrals or skywires from the substation grounding mesh for the ground resistance measurement. In this paper, a method for the grounding performance measurement of multi-grounded systems, which is based on the measuring ground current distributions, has been proposed. A field test results has shown the validity of the proposed test method.