• Proceedings of the KIPE Conference
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• 2004.07b
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• pp.511-514
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• 2004

Proposed about new inverter that can use in PV system in this paper. Multi_level inverter that used inverter makes use of 4 transformers is basis, primary winding of each transformer voltage as can do step_up or step_down to appropriate voltage space tap lake. Put circuit that tap that turn in transformer connects properly according to inhibit signal that sense change of input voltage (output voltage of solar cell place) and transformer secondary voltage controls point of contact of relay so that get into fixed output voltage. As a result, can minimise relative harmonic content despite change width of input voltage are wide because number of output voltage level of multi_level inverter does not decrease. Because proposed circuit manufactures is easy and control is easy and is no burden of cost price rise economically, commercialization expected to do easily and this study examined propriety of action as that compose and experiments proposed circuit.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.4
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• pp.646-652
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• 2015

In this paper, the system-level performance is evaluated for the feedback scheme on the pre-coding matrix index (PMI) and channel quality indication (CQI), which are required for user selection in the multi-user MIMO system. Our analysis demonstrates that the number of users, the number of selected users, and codebook size are the key factors that govern the performance of the best companion grouping (BCG)-based user scheduling. Accordingly, we have confirmed that the probability of forming the co-scheduled user group is determined by these factors, which implies that the number of PMI's and codebook size can be dynamically determined so as to maximize the average system throughput as the number of users varies in the cell.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2003.10a
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• pp.71-74
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• 2003

The cell modeling homogenization method to derive the constitutive equation considering the microstructures of the fiber reinforced composites has been previously developed for composites with simple microstructures such as 2D plane composites and 3D rectangular shaped composites. Here, the method has been further extended for 3D circular braided composites, utilizing B-spline curves to properly describe the more complex geometry of 3D braided composites. For verification purposes, the method has been applied for orthotropic elastic properties of the 3D circular braided glass fiber reinforced composite, in particular for the tensile property. Prepregs of the specimen have been fabricated using the 3D braiding machine through RTM (resin transfer molding) with epoxy as a matrix. Experimentally measured uniaxial tensile properties agreed well with predicted values obtained fer two volume fractions.

• The Transactions of the Korean Institute of Power Electronics
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• v.26 no.1
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• pp.59-65
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• 2021

This study proposes a dead-time implementation method suitable for cell voltage control of a cascaded H-bridge (CHB) inverter. The PWM module of an existing microcontroller cannot generate a maximum voltage due to the dead-time effect when used as the cell controller of the CHB inverter. In the proposed method, the operation method of the PWM module was changed without using the dead time module included in the existing microcontroller, so that the cell output voltage can be increased to the maximum voltage without voltage discontinuity. During the maximum voltage generation period, the full turn-on state can be maintained without unnecessary switching. The validity of the proposed method is confirmed through an experiment.

• Proceedings of the KIPE Conference
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• 2005.07a
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• pp.317-320
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• 2005

본 논문은 멀티-레벨 H-bridge 인버터에서 입력전압 변동에 따른 AVR(Auto Voltage Regulation)기능을 적용 그 타당성을 제안하였다. 기존의 범용 인버터에서 (V/F)로 구동되는 전동기 시스템에 있어서 인버터에 공급되는 입력 전압은 출력 주파수에 따라 출력 전압 비율을 일정하게 하고 기동에 필요한 전압을 더하여 출력하는 방식이다. 집중 제어 방식의 멀티-레벨 H-bridge 인버터에서는 Cell의 DC-Link 전압을 Master에서 받아들여서 각각의 Cell에 기준 전압값을 지령하게 된다. 그러므로 입력 전압 변동에 따른 DC-Link 전압의 변동이 발생하게 되면 상전압 Unbalance 가 발생하게 되어 부하가 원하는 출력 전압을 낼 수가 없게 된다. 또한 각각의 Cell을 제어하는 Master 제어기가 가지고 있는 문제점을 보완하여 각각의 Cell 제어기 스스로가 AVR을 수행하는 좀더 나은 방법을 제안하였다.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10299-10306
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• 2015

The esophageal squamous cell carcinoma (ESCC) is thought to develop through a multi-stage process. Epigenetic gene silencing constitutes an alternative or complementary mechanism to mutational events in tumorigenesis. Posttranscriptional regulation of human leukocyte antigen class I (HLA-I) and antigen processing machinery (APM) proteins expression may be associated with novel epigenetic modifications in cancer development. In the present study, we determined the expression levels of HLA-I antigen and APM components by immunohistochemistry. Then by a bisulfite-sequencing PCR (BSP) approach, we identified target CpG islands methylated at the gene promoter region of APM family genes in a ESCC cell line (ECa109), and further quantitative analysis of CpG site specific methylation of these genes in cases of Kazakh primary ESCCs with corresponding non-cancerous esophageal tissues using the Sequenom MassARRAY platform. Here we showed that the development of ESCCs was accompanied by partial or total loss of protein expression of HLA-B, TAP2, LMP7, tapasin and ERp57. The results demonstrated that although no statistical significance was found of global target CpG fragment methylation level sof HLA-B, TAP2, tapasin and ERp57 genes between ESCC and corresponding non-cancerous esophageal tissues, there was significant differences in the methylation level of several single sites between the two groups. Of thesse only the global methylation level of LMP7 gene target fragments was statistically higher ($0.0517{\pm}0.0357$) in Kazakh esophageal cancer than in neighboring normal tissues ($0.0380{\pm}0.0214$, p<0.05). Our results suggest that multiple CpG sites, but not methylation of every site leads to down regulation or deletion of gene expression. Only some of them result in genetic transcription, and silencing of HLA-B, ERp57, and LMP7 expression through hypermethylation of the promoters or other mechanisms may contribute to mechanisms of tumor escape from immune surveillance in Kazakh esophageal carcinogenesis.

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.915_916
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• 2009

최근 산업계에서는 스위칭 손실을 저감하여 효율 및 성능 개선에 대한 다양한 토폴로지가 제안되고 있다. 특히 소프트 스위칭 방식은 낮은 전압과 전류 스트레스를 갖는 장점으로 인하여 절연형 DC/DC 컨버터에서 인덕터 사용 없이 트랜스포머의 누설리액턴스를 사용한 소프트 스위칭에 대한 연구가 활발히 이루어지고 있다. 본 논문에서는 소프트 스위칭 특성을 갖는 새로운 DC/DC 컨버터 형태를 제안한다.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.45 no.3
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• pp.444-450
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• 1996

A digital hardware architecture for artificial neural network with learning capability is described in this paper. It is a modified hardware architecture known as HANNIBAL(Hardware Architecture for Neural Networks Implementing Back propagation Algorithm Learning). For implementing an efficient neural network hardware, we analyzed various type of multiplier which is major function block of neuro-processor cell. With this result, we design a efficient digital neural network hardware using serial/parallel multiplier, and test the operation. We also analyze the hardware efficiency with logic level simulation. (author). refs., figs., tabs.

• International Journal of Oncology
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• v.54 no.2
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• pp.753-763
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• 2019

The mutation of isocitrate dehydrogenase (IDH)1 (R132H) and IDH2 (R172K) and the induction of hypoxia in various solid tumors results in alterations in metabolic profiles, including the production of the d- or l-forms of 2-hydroxyglutarate (2HG) from α-ketoglutarate in aerobic metabolism in the tricarboxylic acid (TCA) cycle. However, it is unclear whether the oncometabolite d-2HG increases angiogenesis in endothelial cells. Therefore, in this study, we analyzed the levels of various metabolites, including d-2HG, under hypoxic conditions and in IDH2R172K mutant breast cancer cells by mass spectrometry. We then further evaluated the effects of this metabolite on angiogenesis in breast cancer cells. The results revealed that treatment with d-2HG increased the levels of secreted vascular endothelial growth factor (VEGF) in cancer cells and enhanced endothelial cell proliferation in a concentration-dependent manner. Wound healing and cell migration (examined by Transwell assay) were significantly increased by d-2HG to a level similar to that induced by VEGF. Tube formation was significantly stimulated by d-2HG, and chick chorioallantoic membrane angiogenesis was also enhanced by d-2HG. d-2HG activated VEGF receptor (VEGFR)2 and VEGFR2 downstream signaling, extracellular signal-regulated kinase 1/2, focal adhesion kinase, AKT and matrix metalloproteinase (MMP)2. Taken together, the findings of this study suggested that d-2HG induced angiogenic activity via VEGFR2 signaling and increased MMP2 activity.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.2A
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• pp.179-187
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• 2007

As wireless networks evolve to orthogonal frequency division multiple access(OFDMA) systems, inter-cell interference control becomes a critical issue in radio resource management. The allocation of the same channels in neighbor cells cause inter-cell interference, so the channel allocation needs to be taken carefully to lower the inter-cell interference. In distributed channel allocation, each cell independently tries to allocate channels that suffer low interference level. In this paper, under the assumption of static users, we introduce the concept of interference range and use it in designing our two algorithms; basic and combined. The basic algorithm performs interference range detection and determines whether to use the considered channel, while the combined algorithm checks the channel quality in addition to detecting the interference range. The two algorithms dynamically perform channel allocation with low complexity and show good throughput and fairness performance.