• Molecules and Cells
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• v.44 no.7
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• pp.433-443
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• 2021

Multi-omics approaches are novel frameworks that integrate multiple omics datasets generated from the same patients to better understand the molecular and clinical features of cancers. A wide range of emerging omics and multi-view clustering algorithms now provide unprecedented opportunities to further classify cancers into subtypes, improve the survival prediction and therapeutic outcome of these subtypes, and understand key pathophysiological processes through different molecular layers. In this review, we overview the concept and rationale of multi-omics approaches in cancer research. We also introduce recent advances in the development of multi-omics algorithms and integration methods for multiple-layered datasets from cancer patients. Finally, we summarize the latest findings from large-scale multi-omics studies of various cancers and their implications for patient subtyping and drug development.

• International Journal of Precision Engineering and Manufacturing-Green Technology
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• v.9
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• pp.323-347
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• 2021

Remarkable advances in nanomaterials and nanotechnology have led researchers in various fields. The scale effects imparted by nanomaterials are associated with unexpected macroscale phenomena and properties that find many applications. However, multi-functionalization may be accompanied by physical and commercial limitations. Therefore, research must proceed in several different directions. Here, we define multi-functionalization and the electrical applications thereof in terms of increasing performance, addition of new and valuable properties, and multi-physics in play. We deal with sensors, actuators, energy harvesters, and solar cells and explore research that seeks to increase sensitivity, append "stretchability", and facilitate untethered communication. Furthermore, we analyze research trends in materials use and manufacturing, and highlight useful fabrication methods. With the aim of predicting future research trends, our review presents a roadmap that will aid research on sensing and multi-functional applications.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.397-399
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• 2021

In this study, a basic study on the development of a multi-stimulation system was conducted to suppress lung cancer cell proliferation. Stimulation was applied to lung cancer cells using a photo-stimulating system and ultrasonic waves that generate a specific frequency, and the effect of inhibiting proliferation of cells was imaged and quantitatively evaluated. As a result of the experiment, when a single LED, single ultrasound stimulus were applied and ultrasound and LED stimuli were applied at the same time, meaningful results were shown in the proliferation rate of lung cancer cells.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2008.11a
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• pp.55-55
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• 2008

반사방지막은 태양전지 셀 제작에 적용되고 있으며, 효율을 향상시키기 위하여 $SiO_2$, $TiO_2$를 이용한 Multi-layer 반사방지막을 적용하였다. Multi-layer의 효과가 기존의 SiN 반사방지막에 비하여 광수집의 향상에 영향을 주었음을 알 수 있었다.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.11C
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• pp.1164-1170
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• 2002

In the ACE2000 MPLS system, MPLS Interface Module(MIM) is composed of an ATM Interface Module and a HFMA performing a packet forwarding. In the MIM, the HFMA RSAR receive cells from the Physical layer and reassemble the cells. And the IP Lookup controller perform a packet forwarding after packet classification. Forwarded packet is segmented into cells in the HFMA TSAR and transfer to the ALMA for the transmission to an ATM cell switch. When the MIM make use of an ATM Interface Module, it directly connect the ALMA with a PHY layer using the UTOPIA Level2 interface. Then, an ALMA performs Master Mode. Also, the HFMA TSAR performs the Master Mode in the MIM. Therefore, the UTOPIA-L2 Controller of the Slave Mode require for interfacing between an ALMA and a HFHA TSAR. In this paper, we implement the architecture and cell control mechanism for the UTOPIA-L2 Controller supporting Multi-ports.

• Journal of Communications and Networks
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• v.18 no.3
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• pp.364-374
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• 2016

With vast amounts of spectrum available in the millimeter wave (mmWave) band, small cells at mmWave frequencies densely deployed underlying the conventional homogeneous macrocell network have gained considerable interest from academia, industry, and standards bodies. Due to high propagation loss at higher frequencies, mmWave communications are inherently directional, and concurrent transmissions (spatial reuse) under low inter-link interference can be enabled to significantly improve network capacity. On the other hand, mmWave links are easily blocked by obstacles such as human body and furniture. In this paper, we develop a multi-hop relaying transmission (MHRT) scheme to steer blocked flows around obstacles by establishing multi-hop relay paths. In MHRT, a relay path selection algorithm is proposed to establish relay paths for blocked flows for better use of concurrent transmissions. After relay path selection, we use a multi-hop transmission scheduling algorithm to compute near-optimal schedules by fully exploiting the spatial reuse. Through extensive simulations under various traffic patterns and channel conditions, we demonstrate MHRT achieves superior performance in terms of network throughput and connection robustness compared with other existing protocols, especially under serious blockage conditions. The performance ofMHRT with different hop limitations is also simulated and analyzed for a better choice of the maximum hop number in practice.

• Journal of IKEEE
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• v.13 no.4
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• pp.75-81
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• 2009

The cellular system in the next generation decreases the range of transmission of a signal as well as increases the rate of transmission adapting the method of multi-hop relaying with the relay. However, the fact of decreasing the range of transmission with the method of multi-hop relaying means increasing interferential amount in the outer cell; therefore, the deployment of the relay can affect to the function of the cellular system. In this thesis, the deployment of the relay is determined for the maximum rate of transmission, based on the transmission power of the relay and the variation of interferential amount. The condition to determine the deployment of the relay is analyzed with the mathematical model; in addition, its performance is verified through the result of a simulation. Based on the analysis of this thesis, the established deployment and transmission power of the relay to minimize the average outage probability exist. Furthermore, the relay contributes to enlargement of capacity of cells, decreasing the average outage probability in the situation of less severe interference between cells with reuse of frequency. However, the relay should be restrained in use in the situation of severe interference between cells due to the fact that the outage probability of inter-cells can be increased.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.400.1-400.1
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• 2016

Interfacial engineering approaches as an efficient strategy for improving the power conversion efficiencies (PCEs) of inverted polymer solar cells (iPSCs) has attracted considerable attention. Recently, polymer surface modifiers, such as poly(ethyleneimine) (PEI) and polyethylenimine ethoxylated (PEIE), were introduced to produce low WF electrodes and were reported to have good electron selectivity for inverted polymer solar cells (iPSCs) without an n-type metal oxide layer. To obtain more efficient solar cells, quantum dots (QDs) are used as effective sensitizers across a broad spectral range from visible to near IR. Additionally, they have the ability to efficiently generate multiple excitons from a single photon via a process called carrier multiplication (CM) or multiple exciton generation (MEG). However, in general, it is very difficult to prepare a bilayer structure with an organic layer and a QD interlayer through a solution process, because most solvents can dissolve and destroy the organic layer and QD interlayer. To present a more effective strategy for surpassing the limitations of traditional methods, we studied and fabricated the highly efficient iPSCs with mono-layered QDs as an effective multi-functional layer, to enhance the quantum yield caused by various effects of QDs monolayer. The mono-layered QDs play the multi-functional role as surface modifier, sub-photosensitizer and electron transport layer. Using this effective approach, we achieve the highest conversion efficiency of ~10.3% resulting from improved interfacial properties and efficient charge transfer, which is verified by various analysis tools.

• Journal of the Korean Vacuum Society
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• v.22 no.3
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• pp.150-155
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• 2013

Textured surface has been fabricated to reduce the light reflectance from the solar cells. The textured surface is very suitable for the multi-junction III-V solar cells because it can decrease the light reflectance over a large wavelength range. In this study, we have generated a textured structure on InAlP which is used for the window layer of the multi-junction III-V solar cells. Ultra-thin Pt layer (0.7 nm) has been used for wet etching mask. An array of nanosized pyramid shape formed on InAlP surface dramatically reduces the light reflectance up to 13.7% over a large wavelength range (i.e., $0.3{\sim}1.5{\mu}m$).

• Current Photovoltaic Research
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• v.6 no.2
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• pp.31-38
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• 2018

Multijunction solar cells present a practical solution towards a better photovoltaic conversion for a wider spectral range. In this review, we compare different types of multi-ijunction solar cell. First, we introduce thin film multijunction solar cell include to the thin film silicon, III-V material and chalcopyrite material. Until now the maximum reported power conversion efficiencies (PCE) of solar cells having different component sub-cells are 14.0% (thin film silicon), 46% (III-V material), 4.4% (chalcopyrite material) respectively. We then discuss the development of multijunction solar cell in which c-Si is used as bottom sub-cell while III-V material, thin film silicon, chalcopyrite material or perovskite material is used as top sub-cells.