• Journal of Acupuncture Research
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• 제29권3호
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• pp.19-28
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• 2012

Objectives : The aim of this study is to evaluate present clinical evidence of oriental medical treatment for cancer in Korea. Method : A search was performed in the Korean Studies Information, Korea Institute of Science and Technology Information, KoreaMed, Oriental Medicine Advanced Searching Integrated System, National Assembly Library, RISS4u, DBPIA, and Oasis using the keyword 'cancer', 'leukemia', 'malignant tumor', 'lymphoma', 'multiple myeloma', 'melanoma'. The search period spanned between Jan 1, 1980~June 30, 2011 and the results were analyzed and evaluated according to the publication date, journal, method of treatment, type of study, and the primary outcome. Randomized clinical trials (RCTs) and Non randomized clinical trial(NRCT) were reviewed separately. Result : The results yielded 133 trials during the period of Jan 1, 1980~June 30, 2011. Most of the trials were concerned with lung cancer and 94 of the trials were simple case studies or case series studies. 61 trials used herbal Formula/herbal medicine as the primary method of treatment. A total of 4 RCTs existed compared to only one NRCT. Conclusion : The use of oriental medicine for the treatment of cancer is gaining popularity in the field of medical scientific research. However most of the studies that have been published up to date are mostly case studies or case series studies, and RCT/NRCT are rare. In order to provide appropriate evidence regarding the effectiveness of oriental medicine in the treatment of cancer, more rigorous and well-designed studies are warranted.

• Journal of Acupuncture Research
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• 제36권1호
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• pp.33-37
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• 2019

Background: This study was designed to investigate the potential effects of Galgeungyulpitang for whitening and elasticity treatment by examining its effect on melanoma cells. Methods: The effects of Galgeungyulpitang on B16/F10 melanoma cell viability, production of melanin, tyrosinase and elastase, were investigated. Cell viability was measured by colorimetric assay that assesses cell metabolic activity (MTT assay). Melanin was measured by Hosei's method, tyrosinase was measured by Yogi's method and elastase was measured by James's method. Results: At concentrations higher than $500{\mu}g/mL$ Galgeungyulpitang, cell viability was significantly reduced ($p{\leq}0.05$). At concentrations of $500{\mu}g/mL$ and lower, morphological changes were not observed. The rate of melanin synthesis was significantly reduced to $73.49%{\pm}2.92%$ at a concentration of $500{\mu}g/mL$ Galgeungyulpitang compared with untreated cells (p < 0.05). Extracellular tyrosinase production was not significantly decreased in vitro, however, intracellular tyrosinase production was significantly reduced to $76.06%{\pm}2.17%$ when treated with Galgeungyulpitang at a concentration of $500{\mu}g/mL$ compared with the control (p < 0.05). Elastase Type 1 production was significantly reduced to $74.98%{\pm}3.24%$ and $69.62%{\pm}4.66%$ at concentrations of 250 and $500{\mu}g/mL$ Galgeungyulpitang, respectively (p < 0.05). Elastase Type 4 production was significantly reduced to $72.77%{\pm}3.52%$ at concentrations of 250 and $500{\mu}g/mL$ (p < 0.05). Conclusion: The results in this study showed that Galgeungyulpitang may inhibit melanin and tyrosinase synthesis, and inhibit elastase production, suggesting that Galgeungyulpitang may be potentially beneficial for skin whitening and loss of skin elasticity treatments.

• 동의생리병리학회지
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• 제25권6호
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• pp.1061-1068
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• 2011

Moxibustion is a treatment method for cold and pain in Korean medicine. But the systematic study of moxibustion were very few. This study was aimed to survey and evaluate moxibustion study in Korean medicine. We search the moxibustion study in journals related Korean medicine and http://oasis.kiom.re.kr. The period of the study from first issue to August, 2010. The search word were moxibustion, moxa in keyword and moxibustion treatment in title. We totally search 334 articles. But 175 articles were excluded because this study were not exactly moxibustion study, so we included and analyzed 159 articles. The study of moxibustion were 159 articles. Literature review were 35 articles, systematic review 8, heat experiment 10, in vivo or vitro 28 and survey investigation 3. Clinical articles of moxibustion related to Korean medical journals were 76. Before and after study were 31 articles, case report 20, cohort study 7, cross-sectional study 2, nonrandomized study 6, quasi randomized study 1, randomized clinical trials 9. This results showed that moxibustion study were smaller than acupuncture or herb and concentrated to pain and cold syndrome. We need further larger and diverse study of moxibustion.

• Journal of Acupuncture Research
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• 제18권6호
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• pp.240-249
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• 2001

Obejective : Based on ${\ll}$sixty-ninth Nan${\gg}$ (${\ll}$難經${\cdot}$六十九難${\gg}$) the interpromoting of the five element's balance method to discuss following 'when deficiency than should strengthen mother and when excessive than eliminate son' theories. Method : This strengthening and eliminating method is based on Jang-bu organ's balance method when 'east is excessive (liver excessive (肝實 )) and west is deficiency (lung deficiency (肺虛))' then 'eliminate the south and strengthen the north's method. Results : The seventy-fifth Nan (${\ll}$難經${\cdot}$七十五難${\gg}$) explains' son effects mother's excessive and mother effects son's deficiency' theory where it balance method of the inter-overacting five elements controlling Jang-bu organ's differentiations. The eighty-first Nan (${\ll}$難經${\cdot}$八十一難${\gg}$) explains strengthening-eliminating method of 'lung excessive and liver deficiency.' Since there are two different perspective of seventy-fifth and eighty-first Nan, we must compare and discuss to make right point of view. Conclusion : the treatment method in ${\ll}$Nan kyoung sixty ninth nan${\gg}$ could be understood as a view of five element constitutional theory (五行體質理論), the treatment method in ${\ll}$Nan kyoung seventyty-fifth nan${\gg}$ of eleminating fire and strengthning water in case of liver excess and lung defficiency and the treatment method in ${\ll}$Nan kyoung eighty-first nan${\gg}$ of strengthning liver and eleminating lung in case of lung excess and liver defficiency could be understood as a view of the yin-yan constitutional theory (陰陽體質理論).

• Journal of Acupuncture Research
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• 제33권2호
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• pp.181-187
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• 2016

Objectives : The purpose of this report is to introduce a case of osteochondral lesions of the left talus caused by ankle sprain and suggest complex traditional Korean medical care with warm needling therapy as a possible method of conservative treatment. Methods : A 20-year-old male with osteochondral lesions of the left talus complaining of ankle pain and restricted range of movement was treated mainly with warm needling therapy and other combined Korean medicine therapy from January 5, 2015 to January 12, 2015. Improvements of symptoms were measured by American Orthopaedic Foot & Ankle Society Score (AOFAS Score), Visual Analog Scale (VAS) and Range of movement (ROM). Results : During 8 days of treatment, the patient showed gradual improvement in AOFAS score, VAS at rest and at weight bearing position, as well as ROM of the ankle. Conclusion : According to the result, warm needling therapy is a possible conservative treatment for osteochondral lesions of the talus. Further studies are needed regarding possible longterm effects.

• 척추신경추나의학회지
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• 제3권2호
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• pp.53-60
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• 2008

Objectives : The aim of this study is to compare the improvement of Low back pain (LBP) depending on female inpatient's Bone mineral density (BMD) after menopause. Method : We evaluated 10 cases of normal and 25 cases of osteopenia and osteoporosis based on Bone mineral density test among the female inpatients with LBP who were after menopause, admitted at Jaseng Hospital of Oriental Medicine from January 2008 to August 2008. Result : Depending on the analysis of pathogenic cause, most were without specific reason and except that, overwork and lifting heavy weight were the most common reason. Using improvement-analysis based on treating period, the normal group showed higher decrease of Numerical Rating Scale (NRS) than osteopenia and osteoporosis group. Conclusion : Statically, among the female inpatients with LBP, who were after menopause, had no significant differences between the normal group and osteopenia and osteoporosis group's improvement rate, depending on treating period.

• Journal of Acupuncture Research
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• 제28권2호
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• pp.27-41
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• 2011

Objectives : The aim of this study was to examine the effect of manual acupuncture at the bilateral $LI_4$, $ST_{36}$ and $LR_3$ on normal human every 3 minute time interval by using power spectrum analysis. Methods : 25 healthy volunteers participated in this study. 32 channel EEG(Electroencephalogram) measurements were carried out before, during and after acupuncture treatments. In this study, power spectrum was used as a measure of complexity. Statistical analysis was performed using repeated measure ANOVA and Bonferroni method. Results : 1. In acupuncture group, Mean HRT, PSI, Normalized HF decreased significantly. SDNN, Ln(TP), Ln(LF), Ln(VLF), Normalized LF and LF/HF ratio increased significantly. RMSSD, Ln(HF) were not affected. 2. In sham acupuncture group, all indicators were not affected. 3. In control group, mean HRT, Ln(TP) decreased significantly. SDNN, RMSSD, PSI, Ln(LF), Ln(HF), Ln(VLF), normalized LF, normalized HF and LF/HF ratio were not affected. Conclusions : This results suggest that manipulation needling of 6 acupoints induced increase of delta, theta, beta waves. Both manipulation and simple needling induced decrease of alpha wave during 12~15 time intervals.

• 한국한의학연구원논문집
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• 제16권2호
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• pp.125-130
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• 2010

Objectives : The bone proportional cun and body cun have been used widely for the location of acupoints in oriental medical clinic. The aim of this study is to compare the two location methods. Methods : 21 students were examined for the location of 6 acupoints (each 2 points in the 3 parts of upper limb, abdomen, and lower limb) using the twe methods. The data of location were analyzed with t-test. Results : In the upper limb, the data from bone proportional cun and body cun were proved to be different significantly. However, there was no significant difference between the data from the two methods in the abdomen and lower limb. Conclusion : The results of this study demonstrate that the oriental medical doctors should be more careful in the choice of appropriate method for the location of acupoints in the upper limb, while it is not important whether they use bone proportional cun and body cun in the abdomen and lower limb.

• Journal of Acupuncture Research
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• 제18권1호
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• pp.146-156
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• 2001

Objectrve : To research the trends of the study related to aging process, and to establish the direction of the study on aging process. Method : We reviewed the journal and essay about the aging process which are published as well in Korea as in foreign country. Results : 1. The study on the Oriental Medicine field can be classfied with the fourth. first, the study of single herb medication's effect on the aging process. second, the study of multiple herb medication's effect on the aging process. third, the study of herb-acupuncture solution's effect on the aging process. fourth, journal review. We find the fact that the study on the Oriental Medicine is concerned with pathology of deficiency syndrome of the kidneys, retention of phlegm and fluid, blood stasis. 2. On the Western Medicine field, mechanism and pathology of aging pracess primarily has been studied. The mechanism of aging process is classified with 'Wear and tear theory' and 'Genome-based theory'. Among the mechanism of aging process, 'Free radical theory' is the most important. Additionally 'Senescence-Accelerated Mouse' has been studied. 3. We review the journal published in foreign country and its subject was the following: first, moxibustion combined with acu-area skin allograft therapy for the aging was effective, second, the traditional chinese medicine bu-zhong-yi-qi-tang in mice have anti-aging effect. third, the overview Preventive geriatrics of Traditional chinese medicine. 4. We researched anti-aging effect study in the journal of the Korean Acupuncture and Moxibustion, and we found a few journal of Herb-acupuncture solution's anti-aging effect. Hereafter, it is necessory that we will study about relationship between acupuncture-moxibustion therpy and anti-aging effect using Senescence-Accelerated Mouse.

• Journal of Acupuncture Research
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• 제19권6호
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• pp.234-246
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• 2002

Objective : Ankylosing spondylitic is a chronic inflammatory disease which most frequently the sacro-iliac joints of young men and known as rare disease. There was no clinical report on functional assessment of ankylosing spondylitis. In order to evaluate the effect of clinical treatment, it was necessary to apply valuable and useful of assessment. Methods : We evaluate 1 cases of diagnosed patient with askylosing spondylitis by AIMS2, M-HAQ, K-HAQ, BASFI, and BASDAI after a series of herbal acupuncture treatment.(Solution of herbal acupuncture is made of vaporizing extraction method from the prescription Sineumheo 1.) Results : Herbal acupuncture had relieved pain and morning stiffness successfully and recovered ankylosing spondylitis functionally. Conclusion : 1. Herbal acupuncture had relieved pain and morning stiffness of ankylosing spondylitis. 2. AIMS2 was not useful to evaluate ankylosing spondylitis because of long evaluation time and low specificity. 3. Although there is no translation version of them, BASFI, and BASDAI are clinically useful of assessment, because of short evaluation time and high specificity. 4. K-HAQ with M-HAQ is useful to evaluate the treatment of ankylosing spondylitis because of snort evaluation time and high specificity.