• 제목/요약/키워드: mouth preparation

검색결과 57건 처리시간 0.03초

Formulation and Evaluation of Sustained Release Preparation of Ibuprofen Fast-Disintegrating Tablet (FDT)

  • Kim, Kwang-Hyeon;Park, Jun-Bom;Kang, Joo-Hyung;Lee, Kun-Hee;Kang, Chin-Yang
    • Journal of Pharmaceutical Investigation
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    • 제41권1호
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    • pp.51-57
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    • 2011
  • The objective of this study was to enhance the utilitization of Ibuprofen (IBU) by introducing the fast-disintegrating tablet (FDT) form. Presently, IBU is being widely used as a tablet or syrup form. But in contrast to these two formulations, IBU as FDT is not only convenient but also increases the control over the time release of the drug, noted by using Alginate beads. This study was carried out with Sodium Alginate and IBU at the ratios of 1:0, 1:0.5, 1:1, and 1:2 in order to produce a series of beads with different ratios. During the drying process of the beads, talc was added in beads to compare the effects with and without the talc. The final product was scanned with SEM imaging to determine the difference in the surface of the beads. The parameters assessed were the diameter, content assay, dissolution test and effectiveness of time-release. Direct compression method was used to prepare FDT containing IBU bead. The properties of FDT, such as hardness, disintegration time, were investigated. The dissolution profiles of FDT were tested using KP dissolution apparatus 1 (basket method). The results suggest addition of talc and drying the beads made the surface smooth and less vulnerable to clutter into chunks. The size of beads was less than 300 ${\mu}m$ which did not create a sandy feeling in the mouth. Thus, the beads formulation model made the sustained release of the drug possible, the hardness of FDT (1.25~1.50 $Kg/cm^2$) was acceptable and all the values of dissolving period were less than 30 seconds. The dissolution profile of FDT was same as that of IBU bead. The efficient dissolution profile and low price of IBU bead containing Sodium Alginate, the FDT formulation prepared from IBU bead can save the expenses and can improve the convenience of application of this drug.

Location of maxillary intraosseous vascular anastomosis based on the tooth position and height of the residual alveolar bone: computed tomographic analysis

  • Yang, Seung-Min;Kye, Seung-Beom
    • Journal of Periodontal and Implant Science
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    • 제44권2호
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    • pp.50-56
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    • 2014
  • Purpose: The aims of this study were to measure the distance of the intraosseous vascular anastomosis in the anterolateral wall of the maxillary sinus from different reference points, and to correlate the location of the intraosseous vascular anastomosis with the tooth position and the residual bone height of the maxilla. Methods: Computed tomography (CT) images were taken from 283 patients undergoing dental implants placement in the posterior maxilla. Three horizontal lines were drawn at the ridge crest, maxillary sinus floor, and the position of the anastomosis. A vertical second line at the center of each tooth was drawn perpendicular to the horizontal lines. The distance from the ridge crest to the maxillary sinus floor and the distance from the maxillary sinus floor to the bony canal were measured from the intersections of the horizontal and vertical lines. The residual alveolar bone height was used to categorize three groups: group 1,<4 mm; group 2, between 4 and 8 mm; and group 3, >8 mm. Results: The residual bone height values of different tooth positions were significantly different (P=0.0002). The distance from the maxillary sinus floor to the intraosseous vascular anastomosis was significantly different between groups 1 and 3 (P=0.0039). At the molar sites, a moderate negative correlation was found between the residual bone height and the distance from the maxillary sinus floor to the intraosseous anastomosis. The distances of the alveolar ridge crest and the maxillary sinus from the intraosseous vascular anastomosis were not significantly different between sexes. Conclusions: Within the limitations of this study, sites with a higher residual bone height in the molar regions were at a relatively high risk of artery damage during window osteotomy preparation; therefore, we recommend taking more precautions when using a lateral approach for sinus elevation.

Implant-Guided Surgery를 이용한 고정성 임플란트 보철물의 전악 수복 증례 (Full mouth rehabilitation with Implant-Guided Surgery and Fixed prosthesis)

  • 김성모;박진홍;류재준;신상완;이정열
    • 대한치과보철학회지
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    • 제56권2호
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    • pp.126-133
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    • 2018
  • Cone beam computerized tomography (CBCT)의 발전은 환자의 해부학적 구조를 3차원적으로 분석할 수 있게 하였다. Surgical guide는 CBCT와 CAD/CAM, 임플란트 진단 소프트웨어의 접목을 통해 미래의 보철물을 계획하고 적합한 위치에 임플란트를 식립할 수 있게 한다. Guided surgery를 통해 해부학적 구조물에 대한 침범을 최소한으로 줄일 수 있고 보다 재현성 있는 치료계획의 설정이 가능하다. 본 증례는 전악 무치악 환자에게 surgical guide를 이용하여 다수의 임플란트를 식립한 증례로 수술시간을 단축시킬 수 있었으며 임시 보철물을 미리 제작함으로써 보다 쉽게 immediate loading을 시행할 수 있었다. 환자는 개선된 안모와 저작기능에 만족하였다.

교사십이지의 조리가공에 관한 분석적 연구 (1) (A Study on the Cooking in 'The kosa-sibi Jip')

  • 김성미
    • 동아시아식생활학회지
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    • 제3권2호
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    • pp.1-13
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    • 1993
  • This paper has examined and analyzed the ways of making Jang(Korean soybean sauce), vinegar and liquor in terms of food processes, which are mentioned in sooljip 5 and 6 Food collections of 'Kosa-sibi Jip', an encyclopaedia written in Chinese and published in 1789-the eleventh year of King Jung-jo of Chosun Dynasty. There respestively six items of nine items of and thirty three items of the recipe for making jang, vinegar and liquor, Soybean was a major material for making jang. And wheat flour and ground barley were added. Myun-jang was made from only flour. Dong-kook Jojang Bup(oriental soybean sauce preparation) which is the traditional Korean process for making jang from only soybean is recorded in this book. The cereals used in the nine items of the vinegar making recipe were rice(six times), wheat(twice), barley(three times) and wheat flour(once). And fruits are also used. Rice was most used of all these materials. The cereals used in the thirty three items of the liquor-making recipe were regular rice(50%), sticky rice(42.6%) and wheat flour(7.4%) In particular sticky rice was much used for Yakyee Rhue and Bok-sik Rhue for medications. The ways of processing cereals for liquor-making were Jee-ae-bop : steamed rice(52.9%), Jook:thick gruel with cereal (32.3%), Goo-mung Tuck: doughnut-shaped rice cake(8.8%) and Hin-moo-ree Tuck: shawith peless rice cake(2.9%). The three unique processes are as follows. First, in winter when the process of liquor-making did not go on because the jar was cold, the bottle with hot water in was put in the jar and so the aduquate temperature for liquor-making was maintained. Next, in warming up a small double boiler, they prevented effervescence by hanging down thread. Finally. in warming up in a double boiler, they sealed the mouth-piece of the jar and put a handful of wet rice when the rice was completely cooked, it was thought of as the sign that the process of liquor-making was done.

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Quality Characteristics of Orange Sauce according to Sugar Contents for Recipe Standardization

  • Bai, Young-Hee
    • Food Quality and Culture
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    • 제2권1호
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    • pp.37-42
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    • 2008
  • This research examined the quality characteristics of orange sauce samples prepared with different sugar contents in order to create a standardized recipe.In the foodservice industry, attempts have been made to make superior sauces, often resulting in error. In this study, different sugar contents were examined for orange sauce to determine why varied results occur during its preparation as well as the best methodology for preparing orange sauce. Quality characteristics such as color differences, spreadability, and pH were analyzed, as well as sensory evaluations of taste, texture, color and overall acceptability. The pH values of the orange sauce samples ranged from 3.6 to 3.63 and after the initial simmering of ingredients, the weight reduction rates of the sauces were 88, 75, 64, 63, and 64% for sugar contents of 200, 300, 400, 500, and 600 g respectively. Hunter's color L, a, and b values of the samples changed according to the sugar contents after simmering (1st sauce). The L and b values showed similar patterns, where increasing sugar content resulted in higher values; however, in the 2nd sauce, the pattern was reversed. This indicates that the color of the sauce was affected by sugar caramelization during the reduction process; however, the final color was modified by the additions of mayonnaise and butter as well as by aeration. In the sensory evaluation the sample containing 30% sugar (500 g) had significantly higher acceptability scores (p<0.05) for color, mouth feel, appearance, taste, and overall acceptability. Finally, the optimal ingredient ratios of the standardized orange sauce recipe were determine as: 48% total liquid consisting of orange juice and mandarin and orange fruit; 30% sugar; 10% mayonnaise and 11% butter.

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발아현미분을 첨가한 식빵의 품질 특성 (Quality characteristics of the bread with sprouted brown rice flour)

  • 최지호
    • 한국식품조리과학회지
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    • 제17권4호
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    • pp.323-328
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    • 2001
  • 본 연구에서는 발아현미의 자연식품으로써의 이용효과를 극대화 시켜 이를 이용한 기능성 식빵을 제조하기 위해 발아현미분을 첨가하여 식빵을 제조하고 부피, 무게를 측정하여 제빵 특성을 측정하였으며, 식빵의 성분변화를 살펴보기 위해 일반성분, 환원당, 아미노산, 무기질, 지방산 분석을 행하여 영양성분을 분석하고, 관능검사를 실시하였다. 발아된 현미분 첨가량 증가에 따른 제빵특성을 살펴보면, 대조구에 비하여 현미분 10∼30% 첨가 식빵의 경우 완만하게 부피가 감소하였고, 40% 첨가구는 75.48%, 50% 첨가구는 66.29%로 감소하여 빵의 외형이 허물어지는 결과를 보였으며, 현미분양의 증가에 따른 식빵 무게의 큰 변화는 찾아볼 수 없었고, 발아 현미분의 첨가량은 30%정도까지가 적정한 제빵특성을 나타내는 것을 알 수 있었다. 일반성분, 구성 아미노산 함량의 변화는 발아현미분의 첨가량이 증가함에 따라 회분, 단백질, 지방, 환원당, 섬유소 및 구성 아미노산의 함량이 계속적으로 증가하였으나, 무기질, 지방산 함량은 대조군과 비교하여 큰 차이가 없었다. 발아현미분을 혼합하여 제조한 빵의 관능적인 성질은 발아현미분의 첨가량이 많을수록 대조군에 비하여 색, 외관, texture, 입안에서의 느낌에 대한 기호도는 약간 낮았으나, 씹을수록 느껴지는 고소한 맛과 향이 대조군에 비해 좋은 특성을 나타내어 빵에 대한 전체적인 선호도는 발아현미분 첨가량이 많을수록 더 높았다.

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Whey Protein Isolate(WPI)의 대체비율을 달리한 스폰지 케이크의 품질 특성에 관한 연구 (The Quality Characteristics of Sponge Cake with Varied Levels of Whey Protein Isolate)

  • 안명수;김찬희
    • 한국식품조리과학회지
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    • 제23권1호통권97호
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    • pp.41-49
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    • 2007
  • The substitution effects of whey protein isolate(WPI) for egg in the preparation of sponge cake were determined by objective and subjective tests. Milk whey is drained from milk curd as a by-product of cheese manufacture. Whey protein is known as a good nutritional source and a functional material for many processed foods, especially baked goods. WPI contains above 90% whey protein. The specific gravity and viscosity of sponge cakes tend to be affected by WPI substitution. The cooking loss of sponge cakes with WPI substituted for egg(abbreviated as WPI cake) during oven baking was smaller than that made with egg(abbreviated as egg cake) and the specific loaf volume of WPI cake was larger than that of egg cake. The number of pores was highly increased and the size of pores was more uniformly and finely distributed in the cross section of WPI cake than those of egg cake, as observed by scanning electron microscopy(SEM). The hardness, gumminess and chewiness of WPI cake made with 10-20% WPI substitution were the lowest among all the tested cakes, including egg cake, thereby confirming the considerable improvement in their cake qualities. By the results of sensory evaluation, appearance, pore uniformity, softness, chewiness, moistness, flavor, mouth feeling, and overall acceptability of 10-20% WPI substitute cakes were evaluated as being significantly superior to those of all other cakes(p<0.05). These results support the better physicochemical characteristics and sensory evaluations of sponge cake prepared with 10-20% of WPI substitution for egg.

면역활성을 가진 생약복합물을 이용한 빵의 제조 및 특성 (Preparation and Characteristics of Bread by Medicinal Herb Composites with Immunostimulating Activity)

  • 김희숙;강진순
    • 한국식품영양과학회지
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    • 제37권1호
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    • pp.109-116
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    • 2008
  • 생약추출물의 기능성 소재로서 이용 가능성을 조사하고자 황기, 백복령, 맥문동, 오가피, 산약, 구기자, 당귀, 하수오, 기사, 토사자, 백출, 오미자, 표고버섯, 감초 등의 생약재를 이용하여 면역활성 실험을 수행한 결과 MH-1, MH-2 및 MH-3은 대식세포 면역 활성의 지표가 되는 식세포 작용, NO 생산량, 암세포 증식 억제활성, cytokine 생성량 등에서 유의성 또는 높은 활성을 보였기 때문에 기능성 식품 제조를 위한 면역증강 소재로의 활용가치가 있음이 증명되었다. 이와 같이 생약재의 면역 활성능을 확인한 후 면역 활성이 높은 위의 생약 열수 추출물을 그 일정한 비율로 혼합(밀가루를 기준으로 추출물은 30%, 50%, 70%, 100%)하여 반죽의 pH, 제품의 부피, 색도, 기계적 질감, 관능검사를 수행하였다. 반죽의 pH는 다른 모든 처리군에서 대조군(0%)과 유사하였으며 제품의 부피는 70% 추출물 첨가군에서 증가하였으나 다른 모든 처리군에서는 대조군에 비해 감소하였다. 식빵 crust의 색도는 추출물의 첨가량에 따른 L, a, b 값의 변화는 일정하지 않았으며, 식빵 crumb의 색도는 추출물의 첨가량이 증가할수록 L값은 감소하고, a, b값은 모두 증가시켜 어두운 색을 나타내었다. 조직감 측정 시 경도, 응집성, 점착성, 씹힘성 및 복원성은 30% 첨가군이 대조군과 비슷하였으며 추출물의 첨가량에 따라 유의적인 차이를 볼 수 있었다. 관능검사 결과 생약 추출물을 30%와 50% 추출물 첨가 시 외관, 향미, 입안에서의 느낌, 맛, 전반적인 선호도 및 내부의 질감에서는 대조군과 같은 높은 점수를 나타내었으며, 최대첨가수준은 70%까지 가능한 것으로 나타났다.X> CFU/g의 범주에 들었다. 1년간 $-20^{\circ}C$에서 보관한 조피볼락에서는 미생물이 검출되지 않았다. 유해 미생물 검사를 통하여 가공조피볼락 모든 시료에서 유해한 미생물은 검출되지 않았다. 본 연구결과에서 조피볼락을 염장(4% NaCl)하고 훈연, 냉동, 포장 등의 복합적 기술을 병행하여 사용함으로써 원료생선의 상미기간을 1년 이상 연장할 수 있었다. 또한 관능적으로 우수한 기호성, 즉석에서 먹을 수 있는 간편성, 장기저장에 의한 식품 산패, 오염 및 변패 미생물의 생육 등이 발생하지 않는 우수한 생선가공, 저장방법, 저가 생선류의 부가가치 상승 등 여러 유익한 결과를 얻을 수 있는 효과적인 가공방법을 증명하였다.의 평균섭취량에도 미치지 못하는 매우 저조한 영양상태를 보여 경제력, 육체적 활동 및 건강상태 등이 매우 열악한 이들 집단에 대한 질 좋은 영양서비스의 제공이 국가적 차원에서 시급히 재고되어야 할 것이다. 연구대상자 특히 배달급식 대상자의 경우 모집의 어려움으로 인해 적은 수의 연구대상자의 결과를 보고한 것은 본 연구의 제한점이라 할 수 있다 따라서 본 연구결과를 바탕으로 좀 더 많은 대상자를 대상으로 한 조사 연구가 계속 이루어져 가정배달급식 프로그램의 개선을 위한 유용한 자료로 축적되어야 할 것이다.상범주로 회복함을 알수 있었고 실험결과 항암제 투여후 3 일째 피판 형성한 군에서 피판치유가 늦어진 것으로 관찰되어 인체에서 항암 투여후 수술시기는 인체면역계가 회복하는 시기를 3주이상 경과후 적어도 4주째 수술시기를 정하는 것이 유리하리라 생각되었다.한 복합레진은 개발의 초기단계이며, 물성의 증가를 위한 연구가 필요할 것으로 사료된다.또 다른

무치악 환자에서 조직양화제(tissue conditioner)가 시간과 두께에 따라 체적안정성의 변화에 미치는 영향 (Tissue conditioner in edentulous patients, depending on the time and the thickness of the changes affect the dimensional stability)

  • 심연수
    • 한국산학기술학회논문지
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    • 제11권10호
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    • pp.3794-3801
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    • 2010
  • 이 연구는 임상적으로 많이 쓰이는 3종의 조직양화제(Coe-comfort, GC Soft-Liner, Visco-Gel)의 시간에 따른 체적 안정성을 비교하였다. 시편은 10mm의 반경으로 두께를 1.5mm, 3.0mm로 각각 제작하여 두께에 따른 차이를 비교하였다. 체적의 변화는 시편 제작 후 1시간 (baseline), 12시간, 24시간, 36시간, 3일, 7일에 측정하였다. SAS 6.04 통계 package program을 이용하여 ANOVA분석하였다. 실험한 조직양화제에서는 점탄성을 상실하여 조직양화제를 교체하거나 기공 과정을 하기에 적합한 시간은 변형이 적은 혼합 후 36시간~3일이었다. Tissue conditioner의 종류에 따라 시간의 경과에 따른 탄성 변화량에는 유의할 만한 차이가 있었다(p<0.05). 조직양화제 1.5mm, 3.0mm 두께에 의해 체적안정성에 유의한 차이가 있었다(p<0.05). 자체의 이상적인 탄성 변형과 복원력만을 비교 하였을 때를 보면, Visco-Gel 3.0mm군에서 가장 안정적인 체적안정성을 보였다. 또한, 조직 양화제는 재료 간의 체적 안정성에 다양한 범위가 있어 기능인상에 적합한 것을 선택을 하는 것이 중요하다.

흡연이 흡수성 차폐막을 이용한 조직유도재생술의 치유에 미치는 영향 (Influence of Smoking on Short-Term Clinical Results of Periodontal Bone Defects Treated with Regenerative Therapy Using Bioabsorbable Membranes)

  • 강태헌;설양조;이용무;계승범;김원경;정종평;한수부
    • Journal of Periodontal and Implant Science
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    • 제30권2호
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    • pp.305-324
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    • 2000
  • This study compared the short-term(4 months) clinical results of regenerative therapy with bioabsorbable membranes($BioMesh^{(R)}$) and bone allograft for the treatment of periodontal(intrabony and furcation) defects in smokers and nonsmokers.(16 smokers) 32 subjects with 92 defects participated in the study(46 in smokers and 46 in non-smokers). This study also evaluated a bioresorbable barrier with and without decalcified freeze-dried bone allograft(DFDBA). The 92 periodontal defects were randomly treated with either the resorbable barrier alone or resorbable barrier in combination with DFDBA following thorough defect debridement and root preparation with tetracycline. Each patient received both types of treatment modalities. Clinical examinations(probing depth, gingival recession, clinical attachment level, plaque index and gingival index) were carried out immediately before and 4 months after surgery. Significant(p<0.001) gains in mean attachment level were observed for both smokers(2.93mm) and non-smokers(3.30mm) but there were not significant difference between two groups. Similarly, significant reductions in mean probing depthshowed for smokers(4.52mm) and non-smokers(4.26mm). However, when comparing gingival recession, smokers were found to exhibit significantly poorer treatment results(1.59mm vs 0.96mm, p<0.05). Using the split-mouth-design, no statistically significant difference between the two modalities could be detected with regard to pocket depth reduction, gingival recession, or attachment gain. These results illustrate that the attachment gain is better in the non-smoker and the best in the non-smoker with the combination therapy of resorbable barrier and DFDBA than with resorbable barrier alone but smoking had no significant effect on clinical treatment outcome, even though smokers show more significant gingival recession. In addition, both treatments, either resorbable barrier plus DFDBA or resorbable barrier alone, promoted significant resolution of periodontal defects but the addition of DFDBA with a bioabsorbable membrane appears to add no extra benefit to the only membrane treatment.

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