• The Journal of the Korean dental association
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• v.16 no.1 s.104
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• pp.43-50
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• 1978

The purpose of this study is to determine the effects of Cyclophosphamide on the healing process of fractures of the mice. Tweny-one young adult male mice were used. All of them were experimentally fractured in the left mandibular body areas, and Cyclophosphamide 0.1mg. per 30gr. body wt. was administrated intramuscularly to the experimental group. the mice of both control and experimental groups were sacrificed 1,3,5,7,10,14, and 21st day after operations and microscopic slides were made. The author has observed the histopathological findings. The results were as follows; 1. There were no specific difference between the experimental and control group in the early stage (1~5th day after operation) of the healing process of the mandibular fracture. 2. In the healing process of fractures 7-10th day after operation, the fibrous tissure formation and osteoblastic activity were poor in the experimental groop compared with the control group. 3. In the healing process of fractures 14-21th day after operation, the connective tissue and new bone formation were very poor in the experimental group compared with the control group. 4. On the whole, cyclophosphamide affected the experimentally fractured wound to delay healing in the jaw bone of the mice.

• Journal of Bio-Environment Control
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• v.9 no.4
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• pp.237-243
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• 2000

Agricultural machine is currently operated by man power in the greenhouse, which is oppressively hot and humid, and is for a farmer not to work in comfortable circumstances. In the future, agricultural machine will not have to operate by man power, but it will need do by unmanned power. In order to put into the automatic and unmanned operation of agricultural machine, this system was designed and built to move through the fixed path in the greenhouse. This system was composed of guiders(wires), a limit switch, an operating equipment, its software for automatizing a machine in the greenhouse. The guider was connected between the wall pillars, and the equipment was able to slide over the fixed path made of the guider, by rectilinear and rotational motion. A micro mouse was developed with a stepping motor to calculate on the success rate of its operation with the system As might be expected, this system with the micro mouse was moved the moved the paths with a success rate of 100% on the flat plane surface in our laboratory. However, on the sand plane or the other materials plane, the success rate was not better than 80%. If the micro mouse were well operated, the success rate was would be 100%. Based on the results of this research, this system would be expected to operate well on the path made of a simple wire.

• Journal of Korean Neurosurgical Society
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• v.63 no.4
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• pp.433-443
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• 2020

Objective : Osteoporosis is a disease of unbalanced bone metabolism that results in low bone mineral density with increased bone fragility and propensity for fractures. The increased rate of bone fracture due to osteoporosis places a significant burden on public health care expenditures. Therefore, numerous studies have been designed and performed to identify the drugs or health foods that can improve the bone quality or quantity. This study was designed to evaluate and analyze the therapeutic effects of rutin on histomorphometric values of the spine and femur in an osteoporotic mouse model induced by bilateral ovariectomy. Methods : Thirty female ICR mice (8 weeks old) underwent either a sham operation (only abdominal incision, sham group, n=10) or bilateral ovariectomy (n=20). The ovariectomized (OVX) animals were randomly divided into two groups : untreated OVX group (OVX-C, n=10), or rutin-administered group (OVX-R, n=10). The OVX-C group received weight-adjusted doses of saline vehicle and the OVX-R group received 50 mg/kg of rutin intraperitoneally, starting 1 day after surgery. At 4 and 8 weeks after surgery, serum estrogen, osteocalcin, alkaline phosphatase (ALP), and the telopeptide fragment of type I collagen C-terminus (CTX-1) were analyzed. Interleukin (IL)-1β, IL-6, IL-10, and tumor necrosis factor (TNF)-α were also analyzed. Bone histomorphometric parameters of the 4th lumbar vertebra and femur were determined by micro-computed tomography. Results : In OVX-C group, ALP, osteocalcin, CTX-1, IL-1β, IL-6, and TNF-α levels were significantly increased at 4 and 8 weeks compared to sham operation group. Rutin administration after OVX statistically significantly reduced ALP, CTX-1, IL-1β, IL-6, and TNF-α levels at 4 and 8 weeks. Rutin administration also improves bone histomorphometric parameters including trabecular bone volume fraction, trabecular thickness, and trabecular number. Trabecular separation was also decreased in OVX-R group compared to OVX-C group. Conclusion : The present study demonstrated that rutin has therapeutic effects on improving bone histomorphometric values in an OVX mouse model. The improvement in histomorphometric values may be associated with the reduction of osteoclastic activity via inhibition of IL-1β, IL-6, and TNF-α. In future studies, the mechanism for the effect of rutin on osteoporosis should be demonstrated more clearly to use rutin in human osteoporosis.

• Journal of Periodontal and Implant Science
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• v.34 no.1
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• pp.49-59
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• 2004

The goal of periodontal treatment is not only to arrest the progression of the disease but also to promote the functional, esthetic regeneration of the periodontium. Flap operation, bone graft, guided tissue regeneration, growth factors and bone morphogenetic protein have been used for this purpose. Among these techniques of regeneration, alloplastic graft, especially calcium phosphate is getting more attention recently. The purpose of this study was to evaluate the effects of calcium phosphate glass on mouse calvarial cell in vitro. The toxicity of calcium phosphate glass was measured using MTT assay, the synthesis of collagen was measured using collagen assay, and ALP activity was measured. The experimental groups were cultured with calcium phosphate glass(both AQ-, and HT-CPG) in concentration of 0.01, 0.02, 0.1, 0.2g/ml. The results are as follows 1. In concentrations not exceeding 0.02g/ml, both the groups(AQ-CPG, HT-CPG) didn't show any toxicity on mouse calvarial cell(p<0.05). 2. In both the experimental groups are the concentration of 0.02g/ml, collagen expressions were significantly up-regulated (p<0.05). 3. In both the experimental groups are the concentration of 0.02g/ml, ALP activity was not significantly up-regulated, but ALP activity in both experimental groups were greater than control group(p<0.05). The results suggested that the use of calcium phosphate glass may promotes periodontal regeneration. Ongoing studies are necessary in order to determine their regeneration effects.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.45 no.1
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• pp.75-83
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• 2008

We propose a welfare interface using multiple fecial features tracking, which can efficiently implement various mouse operations. The proposed system consist of five modules: face detection, eye detection, mouth detection, facial feature tracking, and mouse control. The facial region is first obtained using skin-color model and connected-component analysis(CCs). Thereafter the eye regions are localized using neutral network(NN)-based texture classifier that discriminates the facial region into eye class and non-eye class, and then mouth region is localized using edge detector. Once eye and mouth regions are localized they are continuously and correctly tracking by mean-shift algorithm and template matching, respectively. Based on the tracking results, mouse operations such as movement or click are implemented. To assess the validity of the proposed system, it was applied to the interface system for web browser and was tested on a group of 25 users. The results show that our system have the accuracy of 99% and process more than 21 frame/sec on PC for the $320{\times}240$ size input image, as such it can supply a user-friendly and convenient access to a computer in real-time operation.

• Transactions of the Korean Society of Automotive Engineers
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• v.14 no.4
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• pp.192-198
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• 2006

The real-time simulator of a turning-type sluice gate actuated by the hydraulic cylinders is developed using a PC and a visual C++ program language. The real-time simulator receives the directional control valve signal selected by the operator using the mouse, updates the state variables of the turning-type sluice gate system responding to the control signal, and draws the moving figures of the sluice gate, cylinder, reserved water every drawing time on the PC monitor. Also, the operator can observe the sluice gate angle, cylinder force, cylinder pressures, and hydraulic power representing the operation of sluice gate system through the PC monitor every drawing time. The simulator can be a very useful tool to design and improve the turning-type sluice gate system.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.41 no.9
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• pp.960-972
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• 1992

This paper deals with the development of expert system in distribution system which combined with graphic user interface. The proposed expert system can recognize and adjust to the system change, and includes the rule bases of security monitoring. Also it provides load transfer algorithm for efficient load distribution. The graphic user environment for expert system is implemented in the mouse-oriented user interface with overlapped window functions and pull-down menus. Therefore, the developed graphic integrated expert system can afford to assist system operators very conveniently through the various graphic function in proposing an optimal plan of load transfer for fault restoration and outage schedule.

• Journal of the Korea Computer Industry Society
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• v.4 no.4
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• pp.449-454
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• 2003

In this paper, GU environmental controller is implemented with USB(Universal serial bus) IF(interface). Especially, the performance examination of ultrasound diagnostic device which connects external USB port with front panel is automatically inspected by VC++ examination program. The test program minimizes the operation of inspector with making the examined result audible or visible, and maximizes the productivity of custom device. The GUI environmental controller controls a standard keyboard, a track ball with dedicated buttons to emulate a standard two-button mouse, switches, rotary encoders, an analog potentiometer group, two alpha-numeric displays. and a touch screen; all of which generate events for the host.

• Proceedings of the IEEK Conference
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• 2003.11a
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• pp.241-244
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• 2003

Nowadays image processing is very useful for some field of traffic applications. The one reason is we can construct the system in a low price, the other is the improvement of hardware processing power, it can be more fast to processing the data. In this study, I propose the traffic monitoring system that implement on the embedded system environment. The whole system consists of two main part, one is host controller board, the other is image processing board. The part of host controller board take charge of control the total system, interface of external environment. and OSD(On screen display). The part of image processing board takes charge of image input and output using video encoder and decoder, image classification and memory control of using FPGA, control of mouse signal. And finally, fer stable operation of host controller board, uC/OS-II operating system is ported on the board.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.193-194
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• 1998

This paper describes a multi-functional EEG (electroencephalogram) software. The software manages the patient's EEG data systematically and analyzes the signal and display the parameters on a PC monitor in real-time. Since the software provides various parameters simultaneously, user can observe patients multilaterally. Reference patterns of CSA and DSA can be captured and displayed on top of the monitor. And user can mark events of surgical operation or patient's conditions, so it is possible to jump to the points of events directly, when reviewing the recorded file afterwards. Many convenient functions are equipped and these are operated by mouse clicks.