• 제목/요약/키워드: mountain ginseng

검색결과 121건 처리시간 0.022초

Comparison of Physicochemical Properties of Extruded Ginseng Samples

  • Ji, Yan-Qing;Yang, Hye-Jin;Tie, Jin;Kim, Mi-Hwan;Ryu, Gi-Hyung
    • Preventive Nutrition and Food Science
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    • 제13권4호
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    • pp.299-305
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    • 2008
  • This study compared the physicochemical properties of root hair of white ginseng (WG), root hair of tissue cultured mountain ginseng (MG), root hair of red ginseng (RG) and extruded ginseng samples. The comparison of crude ash and total sugar resulted insignificant differences between extruded and raw samples. MG had a higher content of crude ash, crude protein, amino acids and polyphenolic compound than WG and RG; the total sugar and reducing sugar were highest in RG. Crude fat and acidic polysaccharide in RG and WG were similar to and higher than MG. Crude saponin of treated samples WG1 (moisture content 25%, barrel temperature $110^{\circ}C$) and WG3 (moisture content 35%, barrel temperature $110^{\circ}C$) were 9.80% and 9.73%, respectively, which were the highest among ginseng samples. In conclusion, the extrusion process can be applied to red ginseng manufacturing, and some characteristics of MG were higher than in RG and WG.

산양삼 잎으로부터 Pancreatic lipase 저해 활성물질의 분리 (Pancreatic Lipase Inhibitors Isolated from the Leaves of Cultivated Mountain Ginseng (Panax ginseng))

  • 홍주연;신승렬;배만종;배종섭;이인철;권오준;정지욱;김용한;김태훈
    • 한국식품저장유통학회지
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    • 제17권5호
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    • pp.727-732
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    • 2010
  • 신선한 산양삼 잎을 EtOH로 침지 추출하여 얻어진 추출물을 n-hexane, EtOAc, n-BuOH 로 용매 분획하였다. 이중 pancreatic lipase 저해활성이 상대적으로 높은 EtOAc 분획에 대해 silica 및 $C_{18}$ column chromatography를 이용하여 3개의 flavonoid 화합물을 분리하였다. 각 화합물의 화학구조는 NMR 스펙트럼 데이터 해석 및 표품과의 HPLC 직접 비교를 통하여 kaempferol-3-O-sophoroside (I), astragalin (II), kaempferol (III)로 동정하였다. 이들 화합물중 kaempferol (III)는 $IC_{50}$ 값이 $9.1{\pm}1.5$ mM로 가장 강한 효능을 나타내었으며, 다음으로 C-3 번 위치에 1개의 glucose가 결합한 astragalin (II)의 $IC_{50}$ 값이 $17.4{\pm}2.7$ ${\mu}M$, C-3 번 위치에 2개의 glucose가 결합한 kaempferol-3-O-sophoroside (I)의 $IC_{50}$ 값이 $20.3{\pm}2.2$ ${\mu}M$의 저해능을 나타내었다. 산양삼 잎의 EtOAc 가용부에에 존재하는 flavonoid계 pancreatic lipase 저해활성 물질을 동정하였으며, 이들 활성은 kaempferol 타입의 화합물은 C-3위치에 당 결합에 의한 hydrophobicity와 관련됨을 시사하였다. 향후 이들 활성물질의 활성 기작에 대한 연구가 필요하며 본 연구결과는 보다 우수한 pancreatic lipase 저해능을 가지는 새로운 선도화합물 발굴을 위한 기초자료로 이용될 수 있을 뿐만 아니라 산양삼잎의 식물 화학적 성분에 대한 기초자료로 이용될 수 있을 것으로 사료된다.

복합한약제제의 수면에 대한 연구 -더웰 제제에 대하여- (Study on Sleeping Behaviors of The Combined-Preparation of Crude Drugs -on The $Well^{TM}$ Preparation-)

  • 방금엽;이미경;서승용;전훈;김대근;오기완;조형권;은재순
    • 동의생리병리학회지
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    • 제25권6호
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    • pp.996-999
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    • 2011
  • This experiment was performed to investigate whether the combined-preparation of crude drugs (The $Well^{TM}$ Preparation, TW), has hypnotic effects and/or enhances pentobarbital-induced sleep behaviors. TW was mixed with water extracts of Ginseng Radix red, Germinated brown rice, cultured mountain ginseng, and 50% ethanol extracts of Longanae Arillus, Nelumbinis Folium and Chrysanthemi Flos. TW (100 mg/kg, p.o.) reduced sleep onset and prolonged sleep time induced by pentobarbital similar to muscimol (0.2 ${\mu}M$), a $GABA_A$ receptor agonist. Also, TW (2 ${\mu}g$/ml) and pentobarbital (2.5 ${\mu}M$) did not affect the chloride influx in primary cultured cerebellar granule cells, respectively, but the combined-treatment of TW (2 ${\mu}g$/ml) and pentobarbital (2.5 ${\mu}M$) increased the chloride influx onto the cells. In conclusion, TW augments pentobarbital-induced sleep behaviors; these effects may result from chloride channel activation.

랫트에서 2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD) 유발 생체 독성에 대한 조직배양 산삼부정근 사포닌의 치유효과 (Therapeutic Effect of Tissue Cultured Root of Mountain Panax ginseng C. A. Mayer Against 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induced Toxicity in Rat)

  • 황석연;박선우;박정숙;한건
    • 약학회지
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    • 제50권4호
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    • pp.220-227
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    • 2006
  • The therapeutic effect of tissue cultured root of mountain ginseng (Panax ginseng) (tcMG) on 2,3,7,8-tetrachlorodaibenzo-p-dioxin (TCDD) induced toxicity in rat was investigated. The rats were assigned into three groups (10 rats/group), control, TCDD exposed group and tcMG treated group after TCDD exposed. $50\;{\mu}g/kg$ of TCDD was injected by i.p. for TCDD exposed group and 30 mg/kg of tcMG saponin was administered for 4 weeks by oral gavage for tcMG treated group. The weights of body, spleen, kidney, thymus, testes and epididymides were decreased in the single TCDD treatment. However these organs was significantly recovered by tcMG saponin except thymus (p<0.05). tcMG decreased the level of hepatic demage maker enzymes, AST and ALP. It also lowered total cholesterol and triglyceride. The level of serum triglyceride was significantly decreased in tcMG saponin treated group compared with the control. Histopathological examination revealed morphological change in the liver spleen, thymus and testes of TCDD treated rats. However they were relatively well preserved in the tcMG treatment group. In conclusion, TCDD induced toxicity was some repaired by tcMG. tcMG may be useful for prevention and treatment of TCDD induced toxicity.

Optimization of Extraction Condition of Methyl Jasmonate-treated Wild Ginseng Adventitious Root Cultures using Response Surface Methodology

  • Liu, Qing;Jo, Yang Hee;Ahn, Jong Hoon;Kim, Seon Beom;Paek, Kee-Yoeup;Hwang, Bang Yeon;Park, So-Young;Lee, Mi Kyeong
    • Natural Product Sciences
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    • 제24권2호
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    • pp.103-108
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    • 2018
  • The usage of wild ginseng (Panax ginseng C.A. Meyer) has been limited due to short supply and high price. Therefore, sufficient production as well as efficient extraction of mountain ginseng are required for the development as products. In this study, wild ginseng adventitious root cultures were prepared for efficient production with advantages of fast growth and stable production. Treatment of methyl jasmonate (MJ) to wild ginseng adventitious root cultures increased the extraction yield and antioxidative activity. Further investigation on effect of extraction conditions suggested the importance of ethanol concentration on antioxidative activity and extraction yield of MJ-treated wild ginseng adventitious root cultures. Optimized extraction condition of MJ-treated wild ginseng adventitious root cultures for maximum extraction yield and antioxidative activity was determined using response surface methodology with three-level-three-factor Box-Behnken design (BBD). Extraction of 1 g MJ-treated wild ginseng adventitious root culture with 30 ml of 9% ethanol at $30^{\circ}C$ produced 310.2 mg extract with 71.0% antioxidative activity at $100{\mu}g/ml$. Taken together, MJ-treated wild ginseng adventitious root culture is valuable source for wild ginseng usage and optimized extraction condition can be used for the development of functional products or folk remedies.

산양삼 경영 표준진단표의 개발 및 현지 적용 (The Development and Application of Standard Diagnostic Table for Mountain Ginseng Management)

  • 전준헌;이성연;이정민;지동현;김연태;강길남
    • 한국산림과학회지
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    • 제103권4호
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    • pp.622-629
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    • 2014
  • 산양삼 재배자가 스스로 경영 수준을 진단하여 문제점을 파악하고 이를 개선해 나갈 수 있도록 경영 표준진단표를 개발하여 활용하고자 하였다. 산양삼 경영 표준진단표는 임가 일반 현황과 경영 성과 지표, 그리고 경영수준 진단을 위한 3개의 대분류 항목 및 18개의 중분류 항목으로 구성되어 있다. 산양삼 경영 표준진단표의 작성을 위해 산양삼 주산단지 15개 시 군 81개 임가의 경영 실태 조사를 실시하였으며 경영수준 진단을 위해서 18개 중분류 항목 점수를 합산하여 총점을 산출하였다. 조사 결과 81개 임가의 평균 점수는 57.2점으로 나타났으며 조사 임가의 58%가 40점 이상 60점 미만에 해당하는 것으로 나타났다. 지역별로 평균점수를 비교해 보면 전북이 52.9점으로 가장 낮고, 경남이 61.4점으로 가장 높게 나타났다. 경영기반 지표에서는 재배자들이 재배 특성상 인위적으로 상을 만들지 않고 재배하는 경우가 많아 채종포 조성(상높이)에 대한 항목의 평균 점수가 1.59점으로 낮게 나타났다. 생산기술 수준 지표에서는 병해충 관리 항목의 평균 점수가 1.28점으로 재배자의 90%이상이 병해충 예찰을 하지 않는 것으로 나타났다. 파종 및 식재방법, 종자에 대한 항목은 경남 함양에서의 평균 점수가 4.00점, 4.47점으로 특히 높게 나타났으며 경영 및 판매능력 지표에서는 경영기록 및 분석 항목의 평균 점수가 2.20점으로 낮게 나타나 여전히 재배 임가에서는 경영기록 등 경영관리가 미흡한 것으로 나타났다.