• Title/Summary/Keyword: mortality

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Genetic and Non-genetic Factors Affecting Mortality in Lori-Bakhtiari Lambs

  • Vatankhah, M.;Talebi, M.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.4
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    • pp.459-464
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    • 2009
  • Data and pedigree information for Lori-Bakhtiari sheep used in this study were 6,239 records of lamb mortality from 246 sires and 1,721 dams, collected from 1989 through 2007 from a Lori-Bakhtiari flock at Shooli station in Shahrekord. The traits investigated were cumulative lamb mortality from birth up to 7 days, up to 14 days, up to 21 days, and up to 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12 months of age. The models included fixed factors that had significant effects and random direct genetic, maternal genetic and maternal permanent environmental effects. Variance components were estimated using the restricted maximum likelihood procedure applying three animal models with and without maternal and common environmental effects. The overall mean of cumulative lamb mortality rate was 22.95% from birth to 1 year of age, while the overall mortality rate up to 3 and from 3 to 6 months of age was 6.14% and 12.76%, respectively. The mortality rate after 6 months of age declined as the lambs grew older. The age of dam had no important effect on lamb mortality. The type of birth was more important during the preweaning period than at later ages, and lamb mortality rate was higher in twins. The year of birth, month of birth and sex of lamb significantly (p${\leq}$0.01) affected the cumulative lamb mortality rate at all ages. The least square mean of mortality during the final one-third of the lambing period was higher than the first and middle onethird of the lambing period. Male lambs were found to be at a higher risk of mortality than females. Birth weight of the lamb had a highly significant (p${\leq}$0.01) effect on lamb mortality at all ages as a quadratic regression. Direct and maternal heritability estimates of lamb mortality ranged from 0.01 to 0.13 and 0.01 to 0.05, respectively. Direct heritability increased with age of lamb, while maternal effects (genetic and common environmental) were important in the preweaning period. These results indicate that lamb mortality can be reduced first through farm management practices and secondly by genetic selection. Both animal and maternal effects should be considered in breeding programmes for reducing lamb mortality at preweaning.

Analysis of Lethality in Echinococcal Disease

  • Khachatryan, Anna S.
    • Parasites, Hosts and Diseases
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    • v.55 no.5
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    • pp.549-553
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    • 2017
  • The information on mortality from echinococcosis is important not only for a better understanding of the severity of the disease, but also for evaluating the effectiveness of public health interventions. The aim of this research was to study the causes of mortality from echinococcosis. We have collected and analyzed the materials of 1,470 patients in 10 age - groups in the Republic of Armenia (from 2000 to 2016). To find out the causes of mortality from echinococcosis, we have analyzed the medical histories and protocols of postmortem examinations of 19 deaths from echinococcosis and 17 deaths due to other indirect causes not associated with the parasite. The average annual death rate from echinococcosis is 0.007 per 10,000 population, and the mortality is 1.29 (per 100 patients). The highest mortality occurs in people aged 70-79. Mortality from echinococcosis is also recorded among the unoperated children. The rupture of the parasitic cyst and hepatic insufficiency are major among the direct causes of mortality. Sometimes the hydatid cysts unrecognized during the life were first diagnosed at autopsy. Insufficient qualification of doctors in the field of helminthology, as well as the latent course of the disease or manifestation of minor symptoms in echinococcosis over a long period often led to medical errors. Further decline in mortality can be achieved by early diagnosis, timely hospitalization and treatment before the development of severe complications worsening the prognosis and outcomes of surgical intervention.

Effects of Human Development Index and Its Components on Colorectal Cancer Incidence and Mortality: a Global Ecological Study

  • Khazaei, Salman;Rezaeian, Shahab;Khazaei, Somayeh;Mansori, Kamyar;Moghaddam, Ali Sanjari;Ayubi, Erfan
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.253-256
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    • 2016
  • Geographic disparity for colorectal cancer (CRC) incidence and mortality according to the human development index (HDI) might be expected. This study aimed at quantifying the effect measure of association HDI and its components on the CRC incidence and mortality. In this ecological study, CRC incidence and mortality was obtained from GLOBOCAN, the global cancer project for 172 countries. Data were extracted about HDI 2013 for 169 countries from the World Bank report. Linear regression was constructed to measure effects of HDI and its components on CRC incidence and mortality. A positive trend between increasing HDI of countries and age-standardized rates per 100,000 of CRC incidence and mortality was observed. Among HDI components education was the strongest effect measure of association on CRC incidence and mortality, regression coefficients (95% confidence intervals) being 2.8 (2.4, 3.2) and 0.9 (0.8, 1), respectively. HDI and its components were positively related with CRC incidence and mortality and can be considered as targets for prevention and treatment intervention or tracking geographic disparities.

Ovarian Cancer in Iranian Women, a Trend Analysis of Mortality and Incidence

  • Sharifian, Abdolhamid;Pourhoseingholi, Mohamad Amin;Norouzinia, Mohsen;Vahedi, Mohsen
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10787-10790
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    • 2015
  • Background: Ovarian cancer is an important cause of mortality in women. The aim of this study was to evaluate the incidence and mortality rates and trends in the Iranian population and make predictions. Materials and Methods: National incidence from Iranian annual of National Cancer Registration report from 2003 to 2009 and National Death Statistics reported by the Ministry of Health and Medical Education from 1999 to 2004 were included in this study. A time series model (autoregressive) was used to predict the mortality for the years 2007, 2008, 2012 and 2013, with results expressed as annual mortality rates per 100,000. Results: The general mortality rate of ovarian cancer slightly increased during the years under study from 0.01 to 0.75 and reaching plateau according to the prediction model. Mortality was higher for older age. The incidence also increased during the period of the study. Conclusions: Our study indicated remarkable increasing trends in ovarian cancer mortality and incidence. Therefore, attention to high risk groups and setting awareness programs for women are needed to reduce the associated burden in the future.

The Impact of Avoidable Mortality on Life Expectancy at Birth in Korea, 1990-2009 (우리나라 피할 수 있는 사망의 기대수명에 미치는 영향)

  • Kim, Young-Bae
    • The Korean Journal of Health Service Management
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    • v.5 no.3
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    • pp.123-132
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    • 2011
  • To evaluate the impact of avoidable mortality on the changes in life expectancy at birth in Korea. Standard life table techniques and the Arriaga method were used to calculate and to decompose life expectancy changes by age, effects and groups of causes of avoidable mortality among two periods(1990-2000 and 2000-2009). A list of causes of avoidable mortality reached by consensus and previously published in Spain was used. Mortality in young adults produced a reduction in life expectancy at birth during the 1990-2000, but there was an important increase in life expectancy at birth during the 2000-2009; in both cases, this was the result of factors amenable to health policy interventions. The highest improvement in life expectancy at birth was due to non-avoidable causes, but avoidable mortality through health service interventions showed improvements in life expectancy at birth in those elderly people than 1 year and in those younger. Making a distinction between several groups of causes of avoidable mortality and using decomposition by causes, ages and effects allowed us to better explain the impact of avoidable mortality on the life expectancy at birth of the whole population and gave a new dimension to this indicator that could be very useful in public health.

Marriage, Sex Role, and Mortality : A Comparison Between Korea and the United States (결혼, 성역할 및 사망력 : 한.미 비교연구)

  • 박경애
    • Journal of Families and Better Life
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    • v.10 no.2
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    • pp.51-59
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    • 1992
  • Previous studies indicated that unmarried persons are subject to higher mortality than the married, and that the differentials are more marked for male than for females. There are two major approaches to explaining the marital status differentials in mortality ; selection function and protection function of marriage. Following protection fucntion, this study develops the new "instrumental / expressive sex-role" hypothesis in order to explain why marriage protects males more against death. The hypothesis expects that male's instrumental role and female's expressive role have direct effect as well as indirect effect through social integration on sex differential mortality by marital status. for the hypothesis testing, Korea and US vital statistics and census data are used to compute age-specific , age-adjusted mortality rates and their ratios for persons in different marital status. Major findings are as follows. 1)For both Korea and US being married is more advantageous to males than females, ad being widowed, divorced, and separated is more disadvantageous to males, while being never-married is more disadvantageous to females, 2) For Korea, the never married men and women have the highest mortality rates, 3) For US the never married women have the highest mortality rate, while the divorced, separated, and widowed men have the highest mortality rate. Fro both Korea and US data, selection function is rejected, but instrumental/expressive sex-role hypothesis succeeds in accounting for the sex and marital status differential in mortality.

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Regional Factors Affecting the Avoidable Mortality: 2010~2019 (회피가능한 사망에 미치는 지역 영향요인 분석: 2010~2019)

  • Lee, Hyun-Ji;Lee, Kwang-Soo
    • Korea Journal of Hospital Management
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    • v.27 no.1
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    • pp.43-57
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    • 2022
  • Background: Avoidable mortality rate has been widely used as an indicator of the quality of health care and the degree of inequality in health levels. The purpose of this study was to identify the factors affecting the avoidable mortality rate in the region. Methods: The data was MDIS(Microdata Integrated Service) Causes of Death Statistics, and the analysis period was from 2010 to 2019. Panel analysis was performed to identify the influencing factors on the avoidable mortality rate. Findings: Result showed that the current smoking rate had a significant positive effects on the avoidable mortality rate of both men and women. And the smoking cessation trial rate, low salt diet rate, weight control trial rate, annual vaccination rate had a significant negative effect. In the social environment, the divorce rate had a significant positive effect. In the economy environment, financial independence and social welfare budget rate had a significant negative effect. In the physical environment, the factory area rate had a significant positive effect. Practical Implication: Practical implication in order to lower the local avoidable mortality rate, various social determinants of health as well as health care resources should be considered together.

A modified Lee-Carter model based on the projection of the skewness of the mortality (왜도 예측을 이용한 Lee-Carter모형의 사망률 예측)

  • Lee, Hangsuck;Baek, Changryong;Kim, Jihyeon
    • The Korean Journal of Applied Statistics
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    • v.29 no.1
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    • pp.41-59
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    • 2016
  • There have been continuous improvements in human life expectancy. Life expectancy is as a key factor in an aging population and can wreak severe damage on the financial integrity of pension providers. Hence, the projection of the accurate future mortality is a critical point to prevent possible losses to pension providers. However, improvements in future mortality would be overestimated by a typical mortality projection method using the Lee-Carter model since it underestimates the mortality index ${\kappa}_t$. This paper suggests a mortality projection based on the projection of the skewness of the mortality versus the typical mortality projection of the Lee-Carter model based on the projection of the mortality index, ${\kappa}_t$. The paper shows how to indirectly estimate future t trend with the skewness of the mortality and compares the results under each estimation method of the mortality index, ${\kappa}_t$. The analysis of the results shows that mortality projection based on the skewness presents less improved mortality at an elderly ages than the original projection.

Trends in Nasopharyngeal Carcinoma Mortality in China, 1973-2005

  • Huang, Tian-Ren;Zhang, Si-Wei;Chen, Wan-Qing;Deng, Wei;Zhang, Chun-Yan;Zhou, Xin-Juan;Zhai, Ri-Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2495-2502
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    • 2012
  • Nasopharyngeal carcinoma (NPC) is a disease with distinct ethnic and geographic distribution. The incidence of NPC in Chinese residing in Asia has declined over the last few decades, but NPC mortality trends in the entire Chinese population over time have not been systematically evaluated. In this study, we examined NPC mortality at the national level in China between 1973-2005. Mortality rates were derived from the databases of national retrospective surveys on cancer mortality conducted in the periods of 1973-1975, 1990-1992, and 2004-2005, respectively. NPC was classified according to the International classification of diseases. Age-adjusted mortality rates were calculated by direct standardization according to the world standard population. Trends in rates were evaluated by age, gender, geographic areas, and socioeconomic status. From 1973 to 2005, there was a general trend of decrease in NPC mortality in China, with higher rates in the south on a downward trend in the north. The age-standardized NPC mortality rates were 2.60 per 100,000 in 1973-1975, 1.94 per 100,000 in 1990-1992, and 1.30 per 100,000 in 2004-2005, respectively. The trend was similar in both men and women, in both urban and rural areas, but the declining rates in females were more remarkable than in males. The mortality rates were higher for the age groups above 50 years than those less than 50 years of age, both showing downward trend over 30-year period. In summary, the overall NPC mortality has consistently decreased in China over the past three decades, particularly in women and in old adults.

A Cohort study on the relationship between pesticide use and mortality, and cancer mortality (농약사용과 사망률과의 관계에 대한 코호트연구)

  • Oh, Hee-Chul;Nam, Chung-Mo;Lee, Sun-Hee
    • Journal of Preventive Medicine and Public Health
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    • v.24 no.3 s.35
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    • pp.390-399
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    • 1991
  • The purpose of this study is to examine the relationship between pesticide use and mortality, and cancer mortality which are recognized as health hazards of pesticides. Data were analyzed from a cohort of 6,066 people aged fifty-five or over and who have been residing in the main island of Kangwha county. Death certificates, computerized citizenship registers searches, and household interview survey lead to get more than ninety-seven percents follow-up rate for the first five year observation period. Important findings are as follows : 1. Age specific mortality rates of pesticide users are significantly lower than those of pesticides nonusers. The SMR of male is 0.80, and 0.58 for females respectively probably due to healthy worker effects. But, age specific cancer mortality rates are significantly higher than those of pesticide nonusers (SMR=1.59) in males. This finding is not observed in females (SMR=0.85), however. 2. Logistic regression analyses showed that self-reported health status, drinking, and smoking histories in male are significantly associated with total mortality rate. The histories of pesticide use are also calculated to be highly associated with cancer mortality as in univariate analyses in males. In female, self-reported health status, age of first delivery are found to be significantly related to total mortality rate. Only drinking history is calculated to be associated with cancer mortalities in females. Data from further observation of 'Kangwha cohort' and indepth analyses of these are highly expected.

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