• 한국실내디자인학회논문집
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• 제19권4호
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• pp.11-21
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• 2010

The purpose of this study is to examine the design characteristic of the facade of the main adminstration building in university. The main administration building which is a basic of educational facilities has various administration setups, such as the register's office, the student affairs section, the planing department, the general affair's office and so on. This building performs academic, administration, facilities management, and admissions service. Also, the building has an ideological, historical, and symbolic image, having an organic relationships with the other educational facilities. This study choose one hundred seven universities, except universities that does not provide information easily and the second campus which does not have the main administration building, as the subjects of the study. The analysis is derived from the design elements applied to facade design of the main administration building and this is divided into design principles(balance symmetry, contrast, rhythm), the formal composition(geometrical, linear), and the style of architecture(classical architecture and modern architecture). The results of the research are summarized as follows: The design characteristic of the facade of the main adminstration building in university has chronologically changed. First of all, in the 1940's, symmetry emphasized on the center of building, superimposition, division, pediment, and arch were marked. Then, superimposition was prominent in the 1950's and symmetry emphasized on the center of building was shown in the 1960s again. Flat roof was in the 1970's, 1990s and 2000's. Finally, pediment was dominant in the 1980's. The design elements of the main administration building can be samples of chronological styles of architecture. Facade design, with proper design of the past and recent times, includes the meaning that achieve the great purpose of the university by emphasizing visual images.

• Parasites, Hosts and Diseases
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• 제55권5호
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• pp.575-578
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• 2017

Aspidogastrid trematodes (Subclass Aspidogastrea) are a relatively small group with a characteristic adhesive disc and parasitize in a variety of cold-blooded hosts. Until now, only 2 species in the genus Cotylaspis, i.e., C. coreensis and C. sinensis, have been reported as the aspidogastrid trematode in the Republic of Korea (=Korea). In the present study, we intended to describe a species of aspidogastrids collected from the small intestine of the common carp, Cyprinus carpio, in a faunistic point of view. Total 51 specimens were collected from a carp caught in Nakdong-gang (River) on May 2015. Some of them were prepared as the specimens for light microscopic observations, and some others were prepared for SEM. They were slightly elongated without head lobes, $2,432{\times}840{\mu}m$ in average size, and had characteristic adhesive discs with 4 rows and 46 alveoli in average. The ovary was reniform and was located in the posterior-upper part of the body. The single testis was larger than the ovary and was located below the ovary. The uterus was coiled containing numerous eggs and distributed in the posterior 2/3 of the body. The vitellaria were follicular, and distributed from the mid-level of testis to near the posterior end. The morphological characters with dimensions of our specimens were closely identical with those of Aspidogaster ijimai previously described. A new aspidogastrid is added among the Korean trematode fauna by the present study.

• 동의생리병리학회지
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• 제22권5호
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• pp.1250-1255
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• 2008

Onchungeum(OCE), a herbal formula, has been used for treatment of anemia, discharging blood and skin diseases. In the previous study, we investigated the anti-cancer effect of OCE by G1 arrest of the cell cycle in human hepatocarcinoma cells, Hep3B cells. In this study, it was examined that the difference of anti-proliferative mechanisms by change in the ratio of OCE composition (OCE I) in Hep3B cells. Treatment of OCE I exhibited a relatively strong anti-proliferative activity and caused various morphological changes such as membrane shrinkage and cell floating. In addition, OCE-I arrests the cell cycle at G1 phase, which was associated with the down-regulation of cyclin D1 and Cdk6 expressions. The G1 arrest was also associated with the induction of Cdk inhibitors p27 and p21. Moreover, both p21 and p27 were detected by immunoprecipitation with anti-Cdk4 and anti-Cdk2 antibodies in OCE I-treated cells but in case of OCE, p21 did not make any complexes with Cdk4 and Cdk2. These results suggest that the change in the ratio of OCE composition might induce different mechanisms in anti-cancer efficacy of OCE, which may confer characteristic principles in oriental medical formula.

• 한국정보통신학회논문지
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• 제24권12호
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• pp.1618-1624
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• 2020

X-ray를 기반으로 하는 장 폐색 진단 방법은 검사자의 주관적인 요소가 포함되기 때문에 객관적 진단에 영향을 미칠 수 있다. 따라서 본 논문에서는 허프 변환과 PCM 클러스터링 기법을 적용하여 장폐색 영역을 추출하는 방법을 제안한다. 제안된 방법은 X-ray 장폐색 영상에서 ROI 영역을 추출한 후, 허프 변환 기법을 이용하여 ROI 영역에서 직선을 검출하고, 검출된 직선을 이용하여 공기 액체층의 형태학적 특징을 이용하여 대장 폐색을 추출한다. 그리고 추출된 ROI 영역을 PCM 클러스터링을 적용하여 ROI 영역을 양자화 한다. 양자화된 ROI 영역 중에서 대장 폐색의 특징이 포함된 클러스터의 그룹을 선정하고, 선정된 클러스터의 그룹에서 객체를 탐색하여 소장 장폐색 영역을 추출한다. 장폐색 환자의 X-ray 영상 30개를 대상으로 PCM 클러스터링을 적용한 결과, PCM의 초기 클러스터의 수를 4개로 설정한 경우가 장폐색 검출 성능이 우수하였고 TPR은 81.47%로 나타났다.

• Parasites, Hosts and Diseases
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• 제58권6호
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• pp.695-699
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• 2020

Present study was performed to know the infection status of Gnathostoma sp. larvae in swamp eels from Cambodia. We purchased total 30 Asian swamp eels, Monopterus albus, from local markets in Pursat and Takeo Provinces and Phnom Penh on May and November 2017 and May 2018. All collected eels were transferred to our laboratory with ice and each of them was examined by artificial digestion method. A total of 15 larval gnathostomes (1-5 larvae) were detected from 55.6% (5/9) swamp eels in Pursat Province. No larval gnathostomes were found in 21 swamp eels in Takeo Province and Phnom Penh. The advanced third-stage larvae (AdL3) detected were 2.575-3.825 (3.250) mm in length and 0.375-0.425 (0.386) mm in width. They had the characteristic head bulb (av. 0.104×0.218 mm) with 4 rows of hooklets, long muscular esophagus (1.048 mm), and 2 pairs of cervical sacs (0.615 mm). The number of hooklets in 4 rows on the head bulb was 41, 44, 47, and 50. In scanning electron microscopy, characteristic features were 4 rows of hooklets on the head bulb, cervical papillae, tegumental spines regularly arranged in transverse striations, and anus. The larval gnathostomes were identified as AdL3 of Gnathostoma spinigerum based on the morphological characters. By the present study, it has been confirmed that G. spinigerum larvae are infected in Asian swamp eels, M. albus, in Pursat Province, Cambodia.

• 생명과학회지
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• 제26권8호
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• pp.875-880
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• 2016

진핵세포의 원형질막은 외부환경으로부터 세포를 격리하는 물리적인 장벽뿐만 아니라, 선택적 물질수송, 신호전달등 중요한 기능을 수행한다. 원형질막의 세포질쪽 지질층은 주로 Phosphatidylethanolamine (PE), Phosphatidylserine (PS), Phosphatidylinositides (PIs) 등의 인지질로 구성되어 있는데, 다양한 단백질들이 이들과 직접 결합하거나 이들의 성질을 이용해 원형질막으로 위치된다. 본 연구에서는 원형질막의 안쪽 지질층에 존재하는 특정 인지질과 결합하여, 원형질막에 위치되는 단백질을 과발현시켰을 때 나타나는 세포의 모양변화를 분석하였다. 이를 위해 PS와 PI등과의 선택적 결합으로 원형질막에 위치하는 단백질들과 소수성 또는 정전기적 상호작용으로 원형질막으로 위치되는 단백질들을 HEK293T세포에 과발현시켜 보았다. 그 결과, 대조군으로 사용한 EGFP 단백질과 PI4P에 선택적으로 결합하는 EGFP-P4M-SidM단백질의 발현은 세포의 모양변화를 유도하지 않았다. 반면, PI(4,5)P₂에 결합하는 EGFP-PLCδ1(PH), PI(3,4,5)P₃에 결합하는 EGFP-AKT1(PH), PI4P와 PI(4,5)P₂에 결합하는 OSH2(PH)x2-EGFP의 발현은 세포의 크기가 줄어드는 수축현상이 일어나면서, Lamilapodia나 Filopodia가 형성되는 것을 확인할 수 있었다. 반면에, PS결합을 통해 원형질막에 위치되는 Lact-C2-EGFP과 소수성결합에 의해 원형질막에 위치되는 ApPDE4 long-form인 L(N20)-EGFP이나, 정전기적인 결합을 통해 원형질막으로 위치되는 ApPDE4 short-form인 S(N-UCR1-2)-EGFP단백질의 경우는 세포의 크기가 줄어드는 수축현상은 일어나지만 Lamilapodia나 Filopodia와 같은 모양변화는 나타나지 않는 것을 확인할 수 있었다. 본 연구를 통해, 특정 인지질에 결합하여 원형질막에 위치되는 단백질들이 각각의 인지질 결합 특성에 따라 분류 가능한 세포의 모양변화가 일어남을 확인할 수 있었다.

• 한국수자원학회논문집
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• 제54권8호
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• pp.629-641
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• 2021

본 연구에서는 2차원 수치모형(Nays2DH)을 적용하여 금강에 건설된 세종보를 중심으로 보 개방 후에 홍수량 변화에 의한 하도의 지형변화 과정을 분석하였다. 이를 위해 부등류, 부정류(단일사상), 연속홍수사상을 수문특성을 반영한 흐름조건으로 수치모의를 수행하였다. 부등류 수치모의 조건은 유황에 따른 정상유량으로 상류단 경계조건을 가정하였다. 부정류와 연속홍수사상의 경우에는 실제 홍수사상들로부터 정규 수문곡선 (normalized hydrograph)을 산정 한 후, 시나리오에 따른 첨두유량으로 정규 수문곡선을 재구성하여 상류단 유량으로 가정하였다. 본 연구에서는 지형학적 변화를 정량적으로 평가하기 위해 하상기복지수(BRI)를 산정하여 시간에 따른 하상변동을 분석하였으며, 연구지역의 항공사진과 수치모의 결과를 정성적으로 비교하였다. 부등류 수치모의 결과, 각 유황별 유량이 증가하면 하폭 대 수심의 비는 감소하고, 사주의 이동속도는 증가하였다. 하상기복지수는 초기에는 증가하지만, 시간이 증가함에 따라 변화량이 작아졌다. 또한 유량이 증가하면 하상기 복지수가 증가했다. 부정류 수치모의 결과 사주의 이동속도는 유량의 변화에 따라 감소했다. 또한 첨두홍수에 대한 지형적 반응에서 시간지체(time lag)가 발생했다. 즉, 부정류에서는 하상고의 변화는 수리학적 조건에 대하여 위상지연(Phase lag) 이 나타났다. 연속홍수사상 발생에 의한 부정류 수치모의 결과에서는 각각 첨두홍수 발생에 따른 사주의 이동속도는 홍수발생이 반복됨에도 불구하고 급격하게 감소했다. 또한 부정류 수치모의 결과와 마찬가지로 위상지연이 나타났으며 사주의 이동속도는 지수적으로 감소하는 특성을 보였다. 하상기복지수는 시간경과에 따라 증가하였으나, 첨두홍수가 연속으로 발생하였음에도 불구하고 하상기복지수의 증가율은 완만하였다. 본 연구를 통해 하천의 수문특성을 반영한 지형변화 과정을 수치모의를 수행하여 분석하였으며, 이를 통해 흐름특성에 따른 하상변동의 정량적인 예측모의를 현장에 적용할 수 있는 방법을 제시할 수 있을 것으로 판단된다.

• Parasites, Hosts and Diseases
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• 제54권2호
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• pp.221-224
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• 2016

A visceral helminth of the squid, Todarodes pacificus, is reported from the East Sea, the Republic of Korea. Total 39 squid samples were purchased from a fish market in Jumunjin-eup, Gangneung-si (City) from August 2014 to July 2015 and were examined for helminth parasites with naked eyes and under a stereomicroscope after opening the abdominal cavity with a pair of scissors. Whitish larval worms were mainly found in the stomach and abdominal cavity of the squid. They were detected in 25 (64.1%) out of 39 squids examined, and the infection density was 7 larvae per infected squid. Spatula-shaped larvae were $8.2{\times}2.0mm$ in average size, round to slightly flattened anteriorly, with round hatching posteriorly, and had characteristic 4 tentacles with numerous hooklets in the scolex. The larvae were identified as the plerocercoid stage of Nybelinia surmenicola by their morphological features. This finding represents a new host record and the first report of N. surmenicola infection in T. pacificus squids from the east coast of Korea.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.352.2-352.2
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• 2016

In recent times, much effort has been concentrated on trivalent rare-earth ions activated ceramics or oxide phosphors to develop display industries due to their promising applications in optoelectronic devices and field-emission displays. To prepare efficient phosphors, citrate sol-gel method is one of the best synthetic methods. Green and blue emissive CaLa2ZnO5:RE3+ nanocrystalline materials are synthesized by a citrate sol-gel method. After the samples annealing at $1100^{\circ}C$, morphological and structural properties are investigated by scanning electron microscope images and X-ray diffraction patterns, respectively. At low electron beam voltage of <5 kV, the visible photoluminescence properties are obtained. Various concentrations of the RE3+ ions exhibited their characteristic emission peaks at different excitation wavelengths, respectively. Similarly, at high electron beam anodic voltage, the cathodoluminescence properties are studied as a function of acceleration voltage and filament current. The chromaticity coordinates are calculated for the optimized CaLa2ZnO5 nanocrystalline luminescent materials.

• 한국환경과학회지
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• 제24권2호
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• pp.261-266
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• 2015

We have analyzed the external morphology and the environment of the foraging site of Vespertilio sinensis. The external morphology was analyzed by twelve parameters and the environment characteristics of the foraging site was analyzed using GIS 10.1 program. The wing membrane was inserted into the ankle of the hind foot and the wing ratio was 1.42, the middle type between broad-short wing type and long-narrow wing type. The fur color was blackish brown but the guard hair color was whitish. The shape of the ear was a rounded triangle and tragus was a fan shape. This study showed that V. sinensis preferred the deciduous forest of the upper forest zone, where human interference was less. We believed that abundance of insects, depending on water system, was closely related to the use of the foraging site. This result showed that the environment characteristics was very similar to the nature preservation zone including Baekyang valley and Keumsun valley in Naejangsan National Park.