• Archives of Pharmacal Research
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• 제14권1호
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• pp.81-86
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• 1991

Dry powder and different extracts of Agave lophantha were tested against Biomphalaria alexandrina. The results showed that the butanol extract has high molluscicidal activity. The activity of the dry powder has been found to be stable under the effect of some simulated field conditions. Also the toxicological effect of the plant on mice was tested through determination of certain parameters such as total protein, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and acid phosphatase enzymes as well as histopathological study on liver and kidney.

• 한국패류학회지
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• 제14권2호
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• pp.85-90
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• 1998

Biomphalaria glabrata와 Indoplanorbis exustus의 알에 대한 식물성 살패제 Brassaia actinophylla (Araliaceae)의 메탄올 추출물을 아치사 농도로 처리하였을 때 효과를 평가하였다. 그 결과 B. actinophylla를 10 mg/1 농도로 처리하였을 때, 두 종류의 패류의 배(embryo)에서 모두 변화를 보였다. Niclosamide를 0.004mg/1로 처리하였을 경우 역시 B. glabrata와 I. exustus의 배 발생을 억제하였다. 따라서 B. actinophylla는 주혈흡충증의 중간숙주는 패류 관리에 있어 세포치사제로 이용될 수 있을 것이다.

• Parasites, Hosts and Diseases
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• 제51권5호
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• pp.537-544
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• 2013

The present study was performed to observe histopathological changes in tissues of Bithynia siamensis goniomphalos (Gastropoda, Bithyniidae) incubated in crude extract solutions of camellia (Camellia oleifera) seed and mangosteen (Garcinia mangostana) pericarp, and furthermore to estimate the molluscicidal effects of 2 plant substances. Substantial numbers of bithyniid snails were incubated in various concentrations of 2 plant solution for 24 hr. As the positive control, snails incubated in various concentrations of niclosamide, a chemical molluscicide, were used. The histopathological findings were observed in sectioned snail specimens of each experimental and control groups. The results showed that both camellia and mangosteen extracts had molluscicidal effects at 24 hr with 50% lethal concentration ($LC_{50}$) at concentrations of 0.003 and 0.002 g/ml, respectively, while niclosamide had $LC_{50}$ at concentrations 0.599 ppm. B. siamensis goniomphalos snail tissues (foot, gill, and digestive system) showed disruption of columnar muscle fibers of the foot, reduction of the length and number of gill cilia, numerous mucous vacuoles, and irregularly shaped of epithelial cells. Irregular apical and calciferous cells, dilatation of the digestive gland tubule, and large hemolymphatic spaces, and irregular apical surfaces, detachment of cilia, and enlargement of lysosomal vacuoles of epidermis were also shown in all groups. By the present study, it is confirmed that 2 plants, camellia and mangosteen, are keeping some substance having molluscicidal effects, and histopathological findings obtained in this study will provide some clues in further studies on their action mechanisms to use them as natural molluscicides.