• Korean Journal of Environmental Biology
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• v.21 no.1
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• pp.18-25
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• 2003

Effects of tributyltin chloride (TBTC) in vitro on mixed function oxygenase (MFO) system on liver microsome of eight marine fish species were investigated. To determine the effects on MFO system, cytochrome P45O (CYP) and cytochrome b5 con-tents, activities of two reductases (NADH-cytochrome b5 reductase and NADPH-cy-tochrome P450 reductase) and four dealkylation enzymes (EROD, PROD, MROD and ECOD) were measured in fish microsoms exposed to TBTC for 20 min. The WP content was reduced to 10% of the control group in 6 out of 8 species exposed to TBTC, whereas there was no significant change in the cytochrome bs content. the response of NAD(P)H dependant reductases depended on fish species. The dealkylation enzyme activities in microsome were also apparently inhibited by TBTC. The degree of inhibition was different among fish species and four enzymes. The EROD activities in eight species were decreased to the range of 1∼65% of control group.

• Structural Engineering and Mechanics
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• v.11 no.6
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• pp.637-650
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• 2001

A structural analysis of cracked R.C. members under instantaneous or sustained loads and imposed displacements is presented. In the first part of the paper the problem of deriving feasible moment-curvature diagrams for a long term analysis of R.C. sections is approached in an exact way by using the Reduced Relaxation Function Method in state I uncracked and the method suggested by CEB in state II cracked. In both states the analysis of the main parameters governing the problem has shown that it is possible to describe the concrete creep behaviour in an approximate way by using the algebraic formulation connected to the Effective Modulus Method. In this way the calculations become quite simple and can be applied in design practice without introducing significant errors. Referring to continuous beams, the structural analysis is then approached in a general way, applying the Force Method and the Principle of Virtual Works. Finally, considering single members, the structural analysis is performed by means of a graphical procedure based on the application of feasible moment-rotation diagrams which allow to easily solve various structural problems and to point out the most interesting aspects of the long term behaviour of cracked R.C. members with rigid or elastically deformable redundant restraints.