• 한국한의학연구원논문집
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• 제14권3호
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• pp.31-39
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• 2008

In a literary work may reflect the socio-enviromental situations of the time. Lee Injae wrote "Sujingyeongheomsinbang" in early $20^{th}$ century, in a time when japanese colonization began and with which the influence of so called modern medicine, western medicine, were increasing. Though this trend was ever increasing the system for education and propagation was not enough and the practice of TKM was still predominant in public. This book reflect the concern of the author about this transitional time. He stat ing that TKM has a strong point in internal medicine while western medicine in external or surgical diseases tries to consolidate both medicines. This opinion is still valid today or at least serve as a reference as this problem still remains us to solve.

• 한방재활의학과학회지
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• 제25권4호
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• pp.65-74
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• 2015

Objectives The purpose of this study is to describe the origin of Wuqinxi and transition to various forms. Also evaluating the feasibility of Wuqinxi as a modern medical exercise. Methods For collecting data, various documents came from China, Taiwan, and Korea. Also we searched Pubmed, KISS, NDSL and National assembly library using "Wuqinxi (오금희)" for clinical trials. Results In this study, Chinese Wuqinxi can be divided into 10 forms, 15 forms, 18 forms, 20 forms, 30 forms and 40 forms while Taiwanese Wuqinxi can be divided into classic form (125 forms) and short form (84 forms). Also we found some evidence that Wuqinxi played a certain role for health promotion. Conclusions These days Wuqinxi has a 8 different major forms and some of the exercises can be used as a preventive medical exercise to promote health for people.

• 한국한의학연구원논문집
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• 제3권1호
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• pp.119-151
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• 1997

Conclusions for the relationship between a conceptional model of stress theory and its examination based on the Oriental medicine; 1. It was considered that a general conception of stress is included into the meaning of Ki in the Oriental medicine. 2. The response-based model to stress could be comparable to a conception of Ki-pathogens interchange In the Onental medicine. 3. The stimulus-based model may be explained as a modern conception of immoderation feeling related with an internal etiological factor, specially injury of seven emotions, among three groups of etiological factors for disease. 4. The feedback conception based on the interaction model could explain the principal of reversible emotion therapy in the nine Ki. 5. In the Oriental medicine, a study to clarify a emotional etiologic factor and its pathophysiologlcal mechanism has been continued for long time before establishment of stress theory.

• Natural Product Sciences
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• 제9권4호
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• pp.205-209
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• 2003

The Korean peninsula, located between the vast Chinese mainland and Japan, has a unique cultural background that goes back five thousand years. In ancient times, the region was deeply influenced by Chinese culture, and traditional medicine in Korea was no exception. The Korean character, HAN GUL (24 alphabets), was invented at in the early 1400s by The Great King Sejong (1397-1450) of the Chosun dynasty. But few changes were made to traditional medicines for about 500 years thereafter. At the start of the 20th century, missionaries from western countries introduced new concepts and techniques of medicine. During the last century, there was enormous development in modern medical sciences. Even today, however, natural medicine -including folk medicine (or traditional Chinese medicine) - plays an important role in Korean health care. In this paper, we will review and discuss traditional Korean medicines as it has evolved over the past three thousand years.

• 척추신경추나의학회지
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• 제1권2호
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• pp.31-39
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• 2006

Objectives: The objective of this study is to investigate the change of Myofascial Meridian treatment as literature. Methods: We arranged many kinds of medical literature related to Myofascial Meridian treatment. Results: The Myofascial Meridian treatment originated from Young-Chu(靈樞) was developed for many centuries. Conclusion: The modern western treatment like Myofascial Pain Syndrome therapy, Rolling therapy, Myofascial Release, Proproioceptive Neuromuscular Facilitation and Kinesio taping treatment is thought to be connected with Myofasical Meridian treatment.

• 한국의사학회지
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• 제34권2호
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• pp.97-108
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• 2021

In this study, we examine Maeng Hwa-seop's academic activities, focusing on articles published in Uirim, JKM (Journal of Korean Medicine), and other branch journals which were affiliated with the Society of Korean Medicine. The present study charts and summarizes the papers published in the above journals. By organizing Maeng Hwa-seop's papers and making tables, we find that his research can be divided into four categories: symptoms and diseases, prescriptions, academic presentations, and translations of medical literatures. Based on this study, we hope that further researches about the academic activities of Maeng Hwa-seop can be conducted in the future.

• Journal of Microbiology and Biotechnology
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• 제33권5호
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• pp.600-606
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• 2023

Dengue virus (DENV) is a widespread arbovirus. To efficiently establish infection, DENV evolves multiple strategies to hijack the host innate immune response. Herein, we examined the inhibitory effects of DENV serotype 2 (DENV2) nonstructural proteins on RIG-I-directed antiviral immune response. We found that DENV2 NS2A, NS2B, NS4A, and NS4B significantly inhibited RIG-I-mediated IFN-β promoter activation. The roles of NS2B in RIG-I-directed antiviral immune response are unknown. Our study further showed that NS2B could dose-dependently suppress RIG-I/MAVS-induced activation of IFN-β promoter. Consistently, NS2B significantly decreased RIG-I- and MAVS-induced transcription of IFNB1, ISG15, and ISG56. Mechanistically, NS2B was found to interact with MAVS and IKKε to impair RIG-I-directed antiviral response. Our findings demonstrated a previously uncharacterized function of NS2B in RIG-I-mediated antiviral response, making it a promising drug target for anti-DENV treatments.

• Advances in Traditional Medicine
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• 제8권2호
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• pp.103-110
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• 2008

Herbal medicine is the use of medicinal plants for prevention and treatment of diseases: it ranges from traditional and popular medicines of every country to the use of standardized and tritated herbal extracts. Generally cultural rootedness enduring and widespread use in a traditional medical system may indicate safety, but also efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra low concentrations or relying on magical-energetic principles. The efficacy and safety assessments of medicines, whether modern or herbal, invariably encounter challenges or problems during the course of pre-clinical and clinical research. Some of the challenges in evidence-based herbal medicinal research are unique, and the researcher must be cognizant of them in order to safeguard the quality of the data obtained. Key challenges are: the quality of raw materials; appropriateness of biological/pharmacological activity assessment methodology, and data interpretation; standardization methodology; pharmacokinetics and bioavailability of active constituents and metabolites; clinical dosage formulation/production; and clinical study designs and outcome measures.

• 대한한의학방제학회지
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• 제12권1호
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• pp.93-104
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• 2004

Recently, more and more natural herbal products are investigated and used popularly. Pharmaceutical companies of Korea are very interested in developing herbal new drugs. And oriental doctors also need popular, modernized form of oriental drugs. The objective of this article is, first, to examine current situations of drug development in Korea, second, to know general concepts of patent and third, to think about new drug development and patent in oriental medicine's point of view. With consideration of oriental medicine's characteristics, concepts of new drug and patent should be improved. Therefore, the oriental pharmaceutical industry and developments of oriental new drugs could be inspired to further efforts.

• 대한한의진단학회지
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• 제24권1호
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• pp.29-52
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• 2020

Objectives In this study, we tried to analyze the expression status and diagnostic application of the disease according to the characteristics of Six Qi. Methods Suwenxuanjiyuanbingshi (Exploration to Mysterious Pathogenesis and Etiology Based on the Plain Questions, 1152), Shoushibaoyuan (Longevity and Life Preservation, 1615), Dongeuibogam (Treasured Mirror of Eastern Medicine, 1613) and two modern works on Six Qi were analyzed for this study. Results Some substrate characteristics presenting Six Qi were extracted from original literatures. Also, we found that the characteristics of Six Qi can be applied to clinical trials by presenting them as three criteria as wind, humidity, and temperature. Conclusions This study suggests.