• Title/Summary/Keyword: model-order reduction

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Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans

  • Lee, Eun Byeol;Kim, Jun Hyeong;An, Chang Wan;Kim, Yeong Jee;Noh, Yun Jeong;Kim, Su Jin;Kim, Ju-Eun;Shrestha, Abinash Chandra;Ham, Ha-Neul;Leem, Jae-Yoon;Jo, Hyung-Kwon;Kim, Dae-Sung;Moon, Kwang Hyun;Lee, Jeong Ho;Jeong, Kyung Ok;Kim, Dae Keun
    • Biomolecules & Therapeutics
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    • v.26 no.6
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    • pp.568-575
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    • 2018
  • In order to discover lifespan-extending compounds made from natural resources, activity-guided fractionation of Zingiber officinale Roscoe (Zingiberaceae) ethanol extract was performed using the Caenorhabditis elegans (C. elegans) model system. The compound 6-gingerol was isolated from the most active ethyl acetate soluble fraction, and showed potent longevity-promoting activity. It also elevated the survival rate of worms against stressful environment including thermal, osmotic, and oxidative conditions. Additionally, 6-gingerol elevated the antioxidant enzyme activities of C. elegans, and showed a dose-depend reduction of intracellular reactive oxygen species (ROS) accumulation in worms. Further studies demonstrated that the increased stress tolerance of 6-gingerol-mediated worms could result from the promotion of stress resistance proteins such as heat shock protein (HSP-16.2) and superoxide dismutase (SOD-3). The lipofuscin levels in 6-gingerol treated intestinal worms were decreased in comparison to the control group. No significant 6-gingerol-related changes, including growth, food intake, reproduction, and movement were noted. These results suggest that 6-gingerol exerted longevity-promoting activities independently of these factors and could extend the human lifespan.

A Pedestrian Detection Method using Deep Neural Network (심층 신경망을 이용한 보행자 검출 방법)

  • Song, Su Ho;Hyeon, Hun Beom;Lee, Hyun
    • Journal of KIISE
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    • v.44 no.1
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    • pp.44-50
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    • 2017
  • Pedestrian detection, an important component of autonomous driving and driving assistant system, has been extensively studied for many years. In particular, image based pedestrian detection methods such as Hierarchical classifier or HOG and, deep models such as ConvNet are well studied. The evaluation score has increased by the various methods. However, pedestrian detection requires high sensitivity to errors, since small error can lead to life or death problems. Consequently, further reduction in pedestrian detection error rate of autonomous systems is required. We proposed a new method to detect pedestrians and reduce the error rate by using the Faster R-CNN with new developed pedestrian training data sets. Finally, we compared the proposed method with the previous models, in order to show the improvement of our method.

Effect of Multi-Swirl Injector on Acoustic Damping for Reduction of Combustion Instability (연소불안정 저감을 위한 다중 스월 인젝터의 음향학적 감쇠기능)

  • Kim, Hyun-Sung;Kim, Byung-Sun;Yoon, Young-Bin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.36 no.1
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    • pp.62-71
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    • 2008
  • Swirl injector with adjustable backhole length was analyzed to suppress high-frequency combustion instability in Liquid Rocket Engines. In order to analyze the effect of swirl injector as an acoustic absorber, swirl injector was regarded as a quarter-wave resonator and its damping capacity is verified in atmospheric temperature. Experiments were carried out with copied tubes on air core because the interior air core volume of injector has a direct effect on damping. From the experimental data, it is proved that increasing the number of injectors mounted at each anti-node point can increase acoustic damping effect. Also, when tuned injectors at 1L, 1T, 1L1T modes simultaneously are installed at each anti-node point of model chamber, the damping effect of tuned injectors with multi modes agree well with it of tuned injectors with single mode.

Optimal Sizing Method of Distributed Energy Resources for a Stand-alone Microgrid by using Reliability-based Genetic Algorithm (신뢰도 기반의 유전자알고리즘을 활용한 독립형 마이크로그리드 내 분산형전원 최적용량 산정 방법)

  • Baek, Ja-Hyun;Han, Soo-Kyung;Kim, Dae-Sik;Han, Dong-Hwa;Lee, Hansang;Cho, Soo-Hwan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.5
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    • pp.757-764
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    • 2017
  • As the reduction of greenhouse gases(GHGs) emission has become a global issue, the microgrid markets are growing rapidly. With the sudden changes in the market, Korean government suggested a new business model called 'Self-Sufficient Energy Islands'. Its main concern is a stand-alone microgrid composed of Distributed Energy Resources(DERs) such as Renewable Energy Sources(RESs), Energy Storage System(ESS) and Fuel Cell, in order to minimize the emission of GHGs. According to these trend, this paper is written to propose an optimal sizing method of DERs in a stand-alone microgrid by using Genetic Algorithm(GA), one of the representative stochastic methods. It is to minimize the net present cost with the variables, size of RESs and ESS. In the process for optimization, the sunless days are considered as additional constraints. Through the case study analysis, the size of DERs installed in a microgrid system has been computed using the proposed method in MATLAB. And the result of MATLAB is compared with that of HOMER(Hybrid Optimization of Multiple Energy Resources), a well-known energy modeling software.

Biokinetics of Protein Degrading Clostridium cadaveris and Clostridium sporogenes in Batch and Continuous Mode of Operations

  • Koo, Taewoan;Jannat, Md Abu Hanifa;Hwang, Seokhwan
    • Journal of Microbiology and Biotechnology
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    • v.30 no.4
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    • pp.533-539
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    • 2020
  • A quantitative real-time polymerase chain reaction (QPCR) was applied to estimate biokinetic coefficients of Clostridium cadaveris and Clostridium sporogenes, which utilize protein as carbon source. Experimental data on changes in peptone concentration and 16S rRNA gene copy numbers of C. cadaveris and C. sporogenes were fitted to model. The fourth-order Runge-Kutta approximation with non-linear least squares analysis was employed to solve the ordinary differential equations to estimate biokinetic coefficients. The maximum specific growth rate (μmax), half-saturation concentration (Ks), growth yield (Y), and decay coefficient (Kd) of C. cadaveris and C.sporogenes were 0.73 ± 0.05 and 1.35 ± 0.32 h-1, 6.07 ± 1.52 and 5.67 ± 1.53 g/l, 2.25 ± 0.75 × 1010 and 7.92 ± 3.71 × 109 copies/g, 0.002 ± 0.003 and 0.002 ± 0.001 h-1, respectively. The theoretical specific growth rate of C. sporogenes always exceeded that of C. cadaveris at peptone concentration higher than 3.62 g/l. When the influent peptone concentration was 5.0 g/l, the concentration of C.cadaveris gradually decreased to the steady value of 2.9 × 1010 copies/ml at 4 h Hydraulic retention time (HRT), which indicates a 67.1% reduction of the initial population, but the wash out occurred at HRTs of 1.9 and 3.2 h. The 16S rRNA gene copy numbers of C. sporogenes gradually decreased to steady values ranging from 1.1 × 1010 to 2.9 × 1010 copies/ml. C. sporogenes species was predicted to wash out at an HRT of 1.6 h.

Estimation of the methane generation rate constant using a large-scale respirometer at a landfill site

  • Park, Jin-Kyu;Tameda, Kazuo;Higuchi, Sotaro;Lee, Nam-Hoon
    • Environmental Engineering Research
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    • v.22 no.4
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    • pp.339-346
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    • 2017
  • The objective of this study is the evaluation of the performance of a large-scale respirometer (LSR) of 17.7 L in the determination of the methane generation rate constant (k) values. To achieve this objective, a comparison between anaerobic (GB21) and LSR tests was conducted. The data were modeled using a linear function, and the resulting correlation coefficient ($R^2$) of the linear regression is 0.91. This result shows that despite the aerobic conditions, the biodegradability values that were obtained from the LSR test produced results that are similar to those from the GB21 test. In this respect, the LSR test can be an indicator of the anaerobic biodegradability for landfill waste. In addition, the results show the high repeatability of the tests with an average coefficient of variance (CV) that is lower than 10%; furthermore, the CV for the LSR is lower than that of the GB21, which indicates that the LSR-test method could provide a better representation of waste samples. Therefore, the LSR method allows for both the prediction of the long-term biodegradation potential in a shorter length of time and the reduction of the sampling errors that are caused by the heterogeneity of waste samples. The k values are $0.156y^{-1}$ and $0.127y^{-1}$ for the cumulative biogas production (GB21) and the cumulative oxygen uptake for the LSR, respectively.

Computation of stress-deformation of deep beam with openings using finite element method

  • Senthil, K.;Gupta, A.;Singh, S.P.
    • Advances in concrete construction
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    • v.6 no.3
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    • pp.245-268
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    • 2018
  • The numerical investigations have been carried out on deep beam with opening subjected to static monotonic loading to demonstrate the accuracy and effectiveness of the finite element based numerical models. The simulations were carried out through finite element program ABAQUS/CAE and the results thus obtained were validated with the experiments available in literature. Six simply supported beams were modelled with two square openings of 200 and 250 mm sides considered as opening at centre, top and bottom of the beam. In order to define the material behaviour of concrete and reinforcing steel bar the Concrete Damaged Plasticity model and Johnson-Cook material parameters available in literature were employed. The numerical results were compared with the experiments in terms of ultimate failure load, displacement and von-Mises stresses. In addition to that, seventeen beams were simulated under static loading for studying the effect of opening location, size and shape of the opening and depth, span and shear span to depth ratio of the deep beam. In general, the numerical results accurately predicted the pattern of deformation and displacement and found in good agreement with the experiments. It was concluded that the structural response of deep beam was primarily dependent on the degree of interruption of the natural load path. An increase in opening size from 200 to 250 mm size resulted in an average shear strength reduction of 35%. The deep beams having circular openings undergo lesser deflection and thus they are preferable than square openings. An increase in depth from 500 mm to 550 mm resulted in 78% reduced deflection.

A study on the operation conditon of Effective Energy Recovery and Greenhouse gas Reduction by the facility using Waste / Biomass fuel (폐기물 및 바이오매스 연료 사용시설의 효율적 에너지회수 및 온실가스 감축을 위한 운전조건에 관한 연구)

  • Joo, Won Hyeog;Yeo, Woon Ho
    • Journal of the Korea Organic Resources Recycling Association
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    • v.28 no.1
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    • pp.83-95
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    • 2020
  • The economic issue of the period of return versus investment has emerged to efficiently utilize the thermal energy of public resource recovery facilities using waste and private thermal source facilities using BIO-SRF. Accordingly, the optimum temperature and pressure facilities are required beyond the traditional designed, constructed and operated. In this study, we analyzed current energy output by different heat and pressure model in domestic facilities, and calculated the characteristics of green-house gas emission. In order to, utilize the thermal energy producing facilities using waste and biomass fuel more efficiently, it is temperature and pressure, which will lead to more lucrative investment and return as well.

A Bidirectional Dual Buck-Boost Voltage Balancer with Direct Coupling Based on a Burst-Mode Control Scheme for Low-Voltage Bipolar-Type DC Microgrids

  • Liu, Chuang;Zhu, Dawei;Zhang, Jia;Liu, Haiyang;Cai, Guowei
    • Journal of Power Electronics
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    • v.15 no.6
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    • pp.1609-1618
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    • 2015
  • DC microgrids are considered as prospective systems because of their easy connection of distributed energy resources (DERs) and electric vehicles (EVs), reduction of conversion loss between dc output sources and loads, lack of reactive power issues, etc. These features make them very suitable for future industrial and commercial buildings' power systems. In addition, the bipolar-type dc system structure is more popular, because it provides two voltage levels for different power converters and loads. To keep voltage balanced in such a dc system, a bidirectional dual buck-boost voltage balancer with direct coupling is introduced based on P-cell and N-cell concepts. This results in greatly enhanced system reliability thanks to no shoot-through problems and lower switching losses with the help of power MOSFETs. In order to increase system efficiency and reliability, a novel burst-mode control strategy is proposed for the dual buck-boost voltage balancer. The basic operating principle, the current relations, and a small-signal model of the voltage balancer are analyzed under the burst-mode control scheme in detail. Finally, simulation experiments are performed and a laboratory unit with a 5kW unbalanced ability is constructed to verify the viability of the bidirectional dual buck-boost voltage balancer under the proposed burst-mode control scheme in low-voltage bipolar-type dc microgrids.

An Analytical Study on Semi-Rigid Connections of 20-Story Braced Steel Structures (20층 가새 철골구조물의 반강접 접합부에 관한 해석적 연구)

  • Kang, Suk-Bong;Kim, Jin-Hyoung
    • Journal of Korean Society of Steel Construction
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    • v.12 no.1 s.44
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    • pp.1-8
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    • 2000
  • In this study, the effect of semi-rigid connections on the structural behavior of 20-story braced steel structure has been investigated utilizing the second-order elastic structural analysis program in which nonlinear behavior of beam-column connections and geometric nonlinearity have been considered. Global effects such as P-delta effect and sway at the top have been studied, as well as distribution of member force and combined stress in structural members as local effects. When the structure subjected to horizontal load and vertical load is equipped with lateral-load resisting system such as braces, replacement of shear connection with semi-rigid connection has not caused any problem in P-delta effect and top lateral displacement. Distribution of member forces resulted in reduction in member size for economic structural design.

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