Background: Tachycardia induced heart failure model would be the model of choice for the dilated cardiomyopathy. This more closely resembles the clinical syndrome and does not require major surgical trauma, myocardial ischemia and pharmacological or toxic depression of cardiac function. When heart failure is progressive, application of new surgical procedures to the faling heart is highly risky. It has been shown that recovery trajectory from heart failure is a new method in decreasing animal mortality. The purpose is to establish the control datas for recovery trajectory in the canine heart failure model. Material and Method: 21 mongrel dogs were studied at 4 stages(baseline, at the heart failure, 4 and 8 weeks after recovery). Heart failure was induced during 4 weeks of continuous rapid pacing using a pacemaker. Eight weeks of trajectory of recovery period was allowed. Indices of left ventricular function and dimension were measured every 2 weeks and the hemodynamics were measured by use of Swan-Ganz catheterization and thermodilution method every 4 weeks. Values were expressed as mean${\pm}$standard deviation. Result: 4(20%) dogs died due to heart failure. Left ventricular end-diastolic volume at the 4 stages were 40.8${\pm}$7.4, 82.1${\pm}$21.1, 59.9${\pm}$7.7 and 46.5${\pm}$6.5ml. Left ventricular end-systolic volume showed the same trend. Ejection fractions were 50.6${\pm}$4.1, 17.5${\pm}$5.8, 36.3${\pm}$7.3, and 41.5${\pm}$2.4%. Blood pressure and heart rate showed no significant changes. Pressures of central vein, right ventricle, pulmonary artery, and pulmonary capillary wedge showed significant increase during the heart failure period, normalizing at the end of recovery period. Stroke volumes were 21.5${\pm}$8.2, 12.3${\pm}$3.5, 17.9${\pm}$4.6, and 15.5${\pm}$3.4ml. Blood norepinephrine level was 133.3${\pm}$60.0pg/dL at the baseline and 479.4${\pm}$327.3pg/dL at the heart failure stage(p=0.008). Conclusion: Development of tachycardia induced heart failure model is of high priority due to ready availability and reasonable amenability to measurements. Recovery trajectory after cessation of tachycardia showed reduction of cardiac dilatation and heart function. Application of new surgical procedures during the recovery period could decrease animal mortality.
The Average Coordinate Referenee System (ACRS) method is developed to reduce experimental errors in human locomotion analysis. Experimentally measured kinematic data is used to conduct analysis in human modeling, and the model accuracy is directly related to the accuracy of the data. However. the accuracy is questionable due to skin movement. deformation of skeletal structure while in motion and limitations of commercial motion analysis system . In this study. the ACRS method is applied to an optically-tracked segment marker system. although it can be applied to many of the others as well. In the ACRS method, each marker can be treated independently. as the origin of a local coordinate system for its body segment. Errors, inherent in the experimental process. result in different values for the recovered Euler angles at each origin. By employing knowledge of an initial, calibrated segment reference frame, the Euler angles at each marker location can be averaged. minimizing the effect of the skin extension and rotation. Using the developed ACRS methodology the error is reduced when compared to the general Euler angle method commonly applied in motion analysis. If there is no error exist in the experimental gait data. the separation and Penetration distance of the femoraltibial joint using absolute coordinate system is supposed to be zero during one gait cycle. The separation and Penetration distance was ranged up to 18 mm using general Euler angle method and 12 mm using the developed ACRS.
It is an important issue to develop quality assessing system for biofuel for the purpose of accelerating the mass production of biofuel. It is particularly challenging to conduct testing method in the mass production of bioethanol while meeting quality specifications such as ASTM (American Society for Testing & Materials) D4806-10. In order to address this challenge, this paper proposes on-line spectroscopic quality assesment system based on Near Infrared spectrum and Partial Least Squares method in Chemometrics. As a result of testing a number of preprocessing methods and Partial Least Squares, it was found out that Savitzky-Golay method showed the best performance in terms of spectrum correction, noise reduction, and model maintenance. The proposed system allows us to assess multiple quality components continuously using spectroscopic facilities with the cheap cost. Since the value of R2 is more than 0.99, it is possible to replace the laboratory analysis.
Journal of the Korea institute for structural maintenance and inspection
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v.18
no.6
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pp.147-154
/
2014
The cable damages of the bridge structures induce very important impact on the structural safety, which implies the close monitoring of the cable damage is required to secure sustained safety of the bridges. Most usual available maintenance techniques are based on the monitoring the change of the natural frequency of the structures by damages. However, existing method are based on vibration method to calculate lateral vibration and system identification can calculate the axial stiffness using sensitivity equation by trial error method. But the frequency study by the longitudinal movement need because of the sag effect in system identification. This study proposes a new method to investigate the damage magnitudes and status. The method improves the accuracies in the magnitudes and status of damages by adopting the natural frequency of longitudinal movement. The study results have been validated by comparing them with the approximate solution of FEM. Thus, the relationship of cable damage and frequency appear with relation that the severe damage has the little frequency. If we know the real frequency we can estimate the cable damage severity using this relationship. This method can be possible the efficient management of the cable damage.
Jongchan Yoon;Suwon Son;Junhyeok Park;Junseong Moon;Jinman Kim
Journal of the Korean GEO-environmental Society
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v.24
no.7
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pp.5-14
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2023
Recently, earthquakes have occurred frequently in worldwide. These earthquakes cause various forms of natural and physical damage. In particular, liquefaction in which the ground shows liquid-like behavior causes great damage to the structure. Accordingly, various liquefaction damage reduction methods are being studied and developed. Therefore, in this study, a method of reducing liquefaction damage in the event of an earthquake applicable to existing structures was studied using the sheet pile method. The 1-G Shaking table test was performed and the ground was constructed with Jumunjin standard sand. A two-story model structure was produced by applying the similitude law, and the input wave applied a sine wave with an acceleration level of 0.6 g and a frequency of 10 Hz. The effect of reducing structure damage according to various embedded depth ratio was analyzed. As a result of the study, the structure settlement when the ground is reinforced by applying the sheet pile method is decreased by about 71% compared to when the ground is not reinforced, and the EDR with minimum settlement is "1". In addition, as the embedded depth ratio is increased, the calculation of the pore water pressure in the ground tends to be delayed due to the sheet pile. Based on these results, the relationship with structural settlement according to the embedded depth ratio is proposed as a relational equation with the graph. The results of this study are expected to be used as basic data in developing sheet pile methods applicable to existing structures in the future.
Journal of the Korea Institute of Building Construction
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v.24
no.4
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pp.447-458
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2024
This study investigates the effectiveness of Building Information Modeling(BIM) software, specifically SketchUp and Revit, in reducing errors during quantity take-off(QTO) for complex building elements. While 3D modeling offers advantages, existing software may not fully account for manufacturing discrepancies, such as variations in concrete cover thickness and reinforcing bar radius. To address this limitation, this research proposes a BIM-based QTO method for high-insulation wall panels with intricate details. The method utilizes a BIM family library, focusing on key parameters like concrete cover thickness and inner radius of shear reinforcement. A case study compared the cross-sectional details of a wall panel modeled in Revit with the actual manufactured specimen. The analysis revealed a 12% reduction in modeled concrete cover thickness and a 1.27 times larger modeled inner radius of the shear bar compared to the real-world values. The proposed method incorporates these manufacturing variations into the Revit model of the high-insulation wall panel. Software like Navisworks facilitates the identification and correction of any material interferences arising from these adjustments. Furthermore, the method employs a unit wall concept(1m2) to account for the volume of various materials, including insulation and splice sleeves at joints. This allows for the identification of a similar existing family within the BIM library(e.g., "Double RC wall with embedded insulation") that reflects the actual material quantities used in the wall panel. By incorporating these manufacturing-induced variations, the proposed method offers a more accurate QTO process for complex high-insulation wall panels. The "Double RC wall with embedded insulation" family within the Revit program serves as a valuable tool for material quantity estimation in such scenarios.
Purpose: This study uses 'Autoregressive Integrated Moving Average Model' to predict the impact of a sharp drop in the base rate due to COVID-19 at the present time when government policies for stabilizing house prices are in progress. The purpose of this study is to predict implications for the direction of the government's house policy by predicting changes in house transaction prices and house rental prices after a sharp cut in the base rate. Research design, data, and methodology: The ARIMA intervention model can build a model without additional information with just one time series. Therefore, it is a time-series analysis method frequently used for short-term prediction. After the subprime mortgage, which had shocked since the global financial crisis in April 2007, the bank's interest rate in 2020 is set at a time point close to zero at 0.75%. After that, the model was estimated using the interest rate fluctuations for the Bank of Korea base interest rate, the house transaction price index, and the house rental price index as event variables. Results: In predicting the change in house transaction price due to interest rate intervention, the house transaction price index due to the fall in interest rates was predicted to change after 3 months. As a result, it was 102.47 in April 2020, 102.87 in May 2020, and 103.21 in June 2020. It was expected to rise in the short term. In forecasting the change in house rental price due to interest rate intervention, the house rental price index due to the drop in interest rate was predicted to change after 3 months. As a result, it was 97.76 in April 2020, 97.85 in May 2020, and 97.97 in June 2020. It was expected to rise in the short term. Conclusions: If low interest rates continue to stimulate the contracted economy caused by COVID-19, it seems that there is ample room for house transaction and rental prices to rise amid low growth. Therefore, In order to stabilize the house price due to the low interest rate situation, it is considered that additional measures are needed to suppress speculative demand.
Image-based traffic information collection systems have entered widespread adoption and use in many countries since these systems are not only capable of replacing existing loop-based detectors which have limitations in management and administration, but are also capable of providing and managing a wide variety of traffic related information. In addition, these systems are expanding rapidly in terms of purpose and scope of use. Currently, the utilization of image processing technology in the field of traffic accident management is limited to installing surveillance cameras on locations where traffic accidents are expected to occur and digitalizing of recorded data. Accurately recording the sequence of situations around a traffic accident in a freeway and then objectively and clearly analyzing how such accident occurred is more urgent and important than anything else in resolving a traffic accident. Therefore, in this research, existing technologies, this freeway attribute, velocity changes, volume changes, occupancy changes reflect judge the primary. Furthermore, We pointed out by many past researches while presenting and implementing an active and environmentally adaptive methodology capable of effectively reducing false detection situations which frequently occur even with the Gaussian Mixture model analytical method which has been considered the best among well-known environmental obstacle reduction methods. Therefore, in this way, the accident was the final decision. Also, environmental factors occur frequently, and with the index finger situations, effectively reducing that can actively and environmentally adaptive techniques through accident final judgment. This implementation of the evaluate performance of the experiment road of 12 incidents in simulated and the jang-hang IC's real-time accident experiment. As a result, the do well detection 93.33%, false alarm 6.7% as showed high reliability.
Journal of Korean Society of Environmental Engineers
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v.22
no.11
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pp.2037-2046
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2000
It has been reported that the inhibition effect of pH on activated sludge follows noncompetitive inhibition kinetics. However. the noncompetitive inhibition kinetic equation can not be directly applied to pH inhibition because of the difficulty in quantification of pH in terms of inhibitor concentration. So, many empirical equations have been developed to describe the pH inhibition effect especially for acidic condition. In this research. the pseudo toxic concentration ($C_{PT}$) concept model to quantify pH inhibition effect on activated sludge was proposed and compared to other existing models. The $C_{PT}$ concept model can explain the reduction of the maximum specific growth rate (${\mu}_{max}$) caused by the pH inhibition more accurately than any other models, at a wide range of pH. The only model parameter. $K_I$ can be easily estimated by Lineweaver-Burk linearization method.
Journal of the Computational Structural Engineering Institute of Korea
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v.31
no.4
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pp.183-190
/
2018
This paper presents optimization of the main spar of Human-Powered Aircraft (HPA) wing. Mass minimization was attempted, while considering large torsional deformation of the beam. Sequential Quadratic Programming (SQP) method was adopted as a relevant tool to conduct structural optimization algorithm. An inner diameter and ply thicknesses of the main spar were selected as the design variables. The objective function includes factors such as mass minimization, constant tip bending displacement, and constant tip twist of the beam. For estimation of bending and torsional deformation, the geometrically exact beam model, which is appropriate for large deflection, was adopted. Properties of the cross sectional area which the geometrically exact beam model requires were obtained by Variational Asymptotic Beam Sectional Analysis (VABS), which is a cross sectional analysis program. As a result, maintaining tip bending displacement and tip twist within 1.45%, optimal design that accomplished 7.88% of the mass reduction was acquired. By the stress and strain recovery, structural integrity of the optimal design and validity of the present optimization procedure were authenticated.
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