• The Journal of Society for e-Business Studies
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• v.18 no.3
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• pp.93-105
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• 2013

Much Interest has focused on social network services such as Facebook and Twitter. Previous research conducted on social network often emphasized the architecture of the social network that is the existence of path between any objects on network and the centrality of the object in the network. However, studies on the semantic association in the network are rare. Studies on searching semantic associations between entities are necessary for future business enhancements. In this research, the ontology based social network analysis is performed. A new method to search and rank relation sequences that consist of several relations between entities is proposed. In addition, several heuristics to measure the strength of the relation sequences are proposed. To evaluate the proposed method, an experiment was performed. A group of social relationships among the university and organizations are constructed. Some social connections are searched using the proposed ranking method. The proposed method is expected to be used to search the association among entities in ontology based knowledge base.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.199-203
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• 2012

Purpose: To evaluate the prognostic value of serum CYFRA21-1, CEA and hemoglobin levels regarding long-term survival of patients with esophageal squamous cell carcinoma (ESCC) treated with concurrent chemoradiotherapy (CRT). Methods: Age, gender, Karnofsky Performance Status (KPS), tumor location, tumor length, T stage, N stage and serum hemoglobin, and CYFRA21-1 and CEA levels before concurrent CRT were retrospectively investigated and related to outcome in 113 patients receiving 5-fluorouracil and cisplatin combined with radiotherapy for ESCC. The Kaplan-Meier method was used to analyze prognosis, the log-rank to compare groups, the Cox proportional hazards model for multivariate analysis, and ROC curve analysis for assessment of predictive performance of biologic markers. Results: The median survival time was 20.1 months and the 1-, 2-, 3-, 5- year overall survival rates were 66.4%, 43.4%, 31.9% and 15.0%, respectively. Univariate analysis showed that factors associated with prognosis were KPS, tumor length, T-stage, N-stage, hemoglobin, CYFRA21-1 and CEA level. Multivariate analysis showed T-stage, N-stage, hemoglobin, CYFRA21-1 and CEA level were independent predictors of prognosis. By ROC curve, CYFRA21-1 and hemoglobin showed better predictive performance for OS than CEA (AUC= 0.791, 0.704, 0.545; P=0.000, 0.000, 0.409). Conclusions: Of all clinicopathological and molecular factors, T stage, N stage, hemoglobin, CYFRA21-1 and CEA level were independent predictors of prognosis for patients with ESCC treated with concurrent CRT. Among biomarkers, CYFRA21-1 and hemoglobin may have a better predictive potential than CEA for long-term outcomes.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1839-1843
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• 2015

Background: MicroRNAs are a class of noncoding RNAs which regulate multiple cellular processes during tumor development. The purpose of this report is to investigate the clinicopathological and prognostic significance of miR-218 in human gliomas. Materials and Methods: Quantitative RT-PCR (qRT-PCR) was conducted to detect the expression of miR-218 in primary normal human astrocytes, three glioma cell lines and 98 paired glioma and adjacent normal brain tissues.Associations of miR-218 with clinicopathological variables of glioma patients were statistically analyzed. Finally, a survival analysis was performed using the Kaplan-Meier method and Cox's proportional hazards model. Results: The expression level of miR-218 in primary normal human astrocytes was significantly higher than that in glioma cell lines (p<0.01). Also, the expression level of miR-218 in glioma tissues was significantly downregulated in comparison with that in the adjacent normal brain tissues (p<0.001). Statistical analyses demonstrated that low miR-218 expression was closely associated with advanced WHO grade (p=0.002) and low Karnofsky performance score (p=0.010) of glioma patients. Kaplan-Meier analysis with the log-rank test showed that patients with low-miR-218 expression had poorer disease-free survival and overall survival (p=0.0045 and 0.0124, respectively). Multivariate analysis revealed that miR-218 expression was independently associated with the disease-free survival (p=0.009) and overall survival (p=0.004) of glioma patients. Conclusions: Our results indicate that miR-218 is downregulated in gliomas and that its status might be a potential valuable biomarker for glioma patients.

• The Journal of Korean Association of Computer Education
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• v.9 no.4
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• pp.15-23
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• 2006

The current 7th Curriculum require elementary students to participate in an independent computer education class one time per week through means of discretion activity. However a national standard of this educational process has yet to be established, which has made regional provincial and city offices of education to choose textbooks for this purpose by discretion, that showed difference in quality, in operating education curriculums related to computer education for each classes in school such as continuing the repetitive contents without any rank or system. Also informatization education, which is one of national policies, might develop educational unbalance to young children who are to become the main characters in the future information society, due to excessive emphasis on aspect of using computer, which develops education mainly based on learning functions of applicable software. Therefore, we are proposing a discretion activity education curriculum model for utilization of computer education in elementary school which is showing regional difference based on former studies. This study will be helpful in substantiating of computer education in elementary schools in the future.

• The Journal of the Korean dental association
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• v.55 no.2
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• pp.116-127
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• 2017

Objectives : The aim of this study was to evaluate the cumulative survival rates of the implants placed into grafted sinus and determine the effect of age, gender, smoking, and systemic disease on the implant cumulative survival rates. Materials and Methods : The retrospective study was performed on 51 implants placed in 26 patients by one dentist at the Dental Implant Center, Seoul National University Dental Hospital in the years 2000-2010. The cumulative survival rates were calculated by the Kaplan-Meier method. The differences within the factors were analyzed using log-rank test and the correlations between the factors and implant survival rates were analyzed using Cox proportional hazard model. Results : 1. Among the total of 51 implants placed in 26 patients, 7 implants failed and 44 implants remained stable. The 1-year, 5-year, and 10-year cumulative survival rates were 92%, 88%, and 85%, respectively. 2. Patients in their 50s and in their 70s showed statistically significant difference in the cumulative survival rates (P < 0.05). Gender and the existence of systemic disease did not show significant results. 3. In the implant treatment, smokers showed 7.5 times higher risk of implant failure than non-smokers (P < 0.05). Conclusion: Implants installed in combination with sinus elevation can be considered as a reliable treatment method.

• Journal of the Korean Data and Information Science Society
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• v.27 no.2
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• pp.429-435
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• 2016

Heritability estimates for daily gain (g), backfat thickness (mm), days to 90kg (day), loin eye depth (mm) and meat percent (%) were 0.40, 0.44, 0.40, 0.25 and 0.48, respectively. Estimates of correlation between breeding value and rank for meat productivity traits by model 1 and 2 were 0.995 1.000 and 0.991 1.000, respectively and highly significant (p< 0.0001), and they were almost identical to the breeding values estimated by different farms. When top 5% and top 10% animals were selected by meat productive traits at different farms, markedly different animals were selected by farms since the selected improvement traits in each farm maintaining closed herds were different. Therefore, it seems to be desirable that superior pigs should be selected after the establishment of evaluation system for genetic performance at national level using the integrated data obtained from various farms.

• Korea Journal of Hospital Management
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• v.21 no.1
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• pp.51-61
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• 2016

This study attempted to investigate how mass media marketing of a hospital influences patient volume. Additionally, the association of patient volume with exposure time and the type of mass media was examined. Data from a university hospital in Bundang (from January 2014 to November 2014) were used. Degree of physicians' mass media marketing was measured by the number of media exposure. Linear mixed model for repeated measures data was run to identify the associations between the number of media exposure and patient volume. First, the number of hospital physician's mass media exposure and new patients and the first visit patients were positively associated. Second, broadcasting media which has relatively significant in patient volume is TV programs such as cultural programs and news. Third, hospital physicians with higher ranks who were exposed to press media receive more patient appointment. Also, nonsurgical hospital physicians who were exposed to press media receive more patients. Fourth, medical treatment activities for hospital staff who hold the rank of Professor in case of making an appearance at press media have relatively increased. Hospital physician's media exposure, particularly TV programs, was significantly related to patient volume for outpatients.

• Information Systems Review
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• v.4 no.1
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• pp.111-130
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• 2002

The Internet is changing or even eliminating old organizational schemes, including education. A growing number of universities and graduate schools are creating curriculums to reflect these changes. Business schools have prepared their students for a corporate world to offer some E-commerce courses. While E-commerce courses are proliferating in computer and information science schools, they are also spreading to other university departments including law and advertising. The objective of this paper is to suggest a prototype E-commerce curriculum for E-commerce departments. First, we survey and compare the E-commerce curriculum offered in many universities. Second, we provide the new E-commerce curriculum model for Korean universities. E-courses are classified as three knowledge areas of E-commerce courses such as business, technology, and core. We prioritize E-courses selected and rank their importance through an exploratory study for suggesting the undergraduate or graduate curriculum.

• Communications for Statistical Applications and Methods
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• v.24 no.3
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• pp.241-254
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• 2017

Drawing a sample can be costly or time consuming in some studies. However, it may be possible to rank the sampling units according to some baseline auxiliary covariates, which are easily obtainable, and/or cost efficient. Ranked set sampling (RSS) is a method to achieve this goal. In this paper, we propose a modified approach of the RSS method to allocate units into an experimental study that compares L groups. Computer simulation estimates the empirical nominal values and the empirical power values for the test procedure of comparing L different groups using modified RSS based on the regression approach in analysis of covariance (ANCOVA) models. A comparison to simple random sampling (SRS) is made to demonstrate efficiency. The results indicate that the required sample sizes for a given precision are smaller under RSS than under SRS. The modified RSS protocol was applied to an experimental study. The experimental study was designed to obtain a better understanding of the pathways by which positive experiences (i.e., goal completion) contribute to higher levels of happiness, well-being, and life satisfaction. The use of the RSS method resulted in a cost reduction associated with smaller sample size without losing the precision of the analysis.

• Journal of Korean Neurosurgical Society
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• v.57 no.2
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• pp.108-113
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• 2015

Objective : Although the L5-S1 has distinct structural features in comparison with other lumbar spine segments, not much is known about adjacent segment degeneration (ASD) at the L5-S1 segment. The aim of study was to compare the incidence and character of ASD of the cephalad and L5-S1 segments after L5 floating lumbar fusion. Methods : From 2005 to 2010, 115 patients who underwent L5 floating lumber fusion were investigated. The mean follow-up period was 46.1 months. The incidence of radiological and clinical ASD of the cephalad and the L5-S1 segments was compared using survival analysis. Risk factors affecting ASD were analyzed using a log rank test and the Cox proportional hazard model. Results : Radiological ASD of the L5-S1 segment had a statistically significant higher survival rate than that of the cephalad segment (p=0.001). However, clinical ASD of the L5-S1 segment was significantly lower survival rates than that of the cephalad segment (p=0.038). Risk factor analysis showed that disc degeneration of the cephalad segment and preoperative spinal stenosis of the L5-S1 segment were risk factors. Conclusion : In L5 floating fusion, radiological ASD was more common in the cephalad segment and clinical ASD was more common in the L5-S1 segment. At the L5-S1 segment, the degree of spinal stenosis appears to be the most influential risk factor in ASD incidences, unlike the cephalad segment.