• Title/Summary/Keyword: model factor

Search Result 11,942, Processing Time 0.039 seconds

Effect of light-emitting diodes on cordycepin production in submerged Cordyceps militaris cultures

  • Ha, Si-Young;Jung, Ji-Young;Park, Jai-Hyun;Lee, Dong-Hwan;Choi, Ji-Won;Yang, Jae-Kyung
    • Journal of Mushroom
    • /
    • v.18 no.1
    • /
    • pp.10-19
    • /
    • 2020
  • Light is an important factor for cordycepin production in Cordyceps militaris. We investigated the effects of different light-emitting diode (LED) conditions including various LED wavelengths and their combinations on cordycepin production in Cordyceps militaris cultivated in submerged culture. The results of our study showed that the combinations of LED wavelengths were more beneficial than single LED sources for cordycepin production. Among the three tested wavelength combinations, the greatest effects for cordycepin production were observed for the red:blue light combination at the wavelength ratio of 5:5 or 3:7. The optimal culture conditions were 19.2278 h/day of illumination time; 9.19497 g/50 mL of glucose content in the media; and 53.112 h of cultivation time. Our model predicted a maximum yield of 2860.01 ㎍/mL cordycepin. Finally, to verify the calculated maximum, we performed experiments in the culture media representing the obtained optimum combination and the cordycepin yield of 2412.5 ㎍/mL.

Review of the Neuroscientific Evidences for the People With Schizophrenia (조현병 환자의 신경과학적 근거에 대한 고찰)

  • Shin, Eun-Sik
    • Therapeutic Science for Rehabilitation
    • /
    • v.2 no.1
    • /
    • pp.5-12
    • /
    • 2013
  • The purpose of this review is to address the flow of current neuroscientific researches and to provide for the clinicians with therapeutic evidences for schizophrenia which can help them clinical decision making. Since the very beginning, a lot of scientific studies about schizophrenia have been undertaken. In this review, I describes the evidences focused on development of schizophrenia including neurobiological dysfunction, neurodevelopmental model, Kalirin, and Brain-Derived Neurotrophic Factor(BDNF) and neuroanatomic abnormalities based on neuroimaging studies. In conclusion, schizophrenia influencing on broad impairment of human function such as activities of daily life, occupations, and relationships has been studied underlying causes and treatments, but still remained uncertainty. However, there are plenty of useful evidences available for the clinicians to make a good therapeutic choice.

Experimental Study on the Damping Estimation of the 5×5 Partial Fuel Assembly (5×5 부분핵연료 집합체의 감쇠추정을 위한 실험적 연구)

  • Lee, Kang-Hee;Yoon, Kyung-Ho;Song, Kee-Nam
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.16 no.2 s.107
    • /
    • pp.163-168
    • /
    • 2006
  • The PWR Nuclear Fuel assembly consists of more than 250 fuel rods that are supported by leaf springs in the cells of more than 10 Spacer Grids (SG) along the rod length. Since it is not easy to conduct mechanical tests on a full-scale model basis, the small-scaled rod bundle $(5\times5)$ which is called partial fuel assembly is generally used for various performance tests during the development stage. As one of the small-scaled tests, a flow test should be carried out in order to verify the performance of the spacer grid to obtain the Flow-Induced Vibration (FIV) characteristics of the scaled fuel assembly over the specified flow range. A vibration test should be also performed to obtain the modal parameters of the assembly prior to the flow test. In this study, we want to develop the estimation procedure of the damping ratio for the scaled test assembly. For the damping factor of the partial fuel assembly and the grid cage at the first vibration mode, as one of the vibration tests, a so-called pluck testing has been performed in air as a preliminary test prior to in-flow damping measurement test. Logarithmic decrement method is used for calculation of the damping ratio. Estimated damping ratio of the partial fuel assembly is about $0.7\%$ with reasonable error of $2\%$ for the previous results. Nonlinear behavior of the partial fuel assembly might be stem mainly from the rod-grid support configuration.

Factors Influencing Physicians' Prescriptions in Some Frequent Diseases (일부 다빈도 질환에서 개원의의 의약품 처방에 영향을 미치는 요인)

  • 박실비아;문옥륜;강영호
    • Health Policy and Management
    • /
    • v.8 no.2
    • /
    • pp.166-190
    • /
    • 1998
  • This study presents the status on drug prescription for clinic outpatients' bronchitis, gastritis, and gastric ulcer, and also the physician factors that affects their prescriptions. In this research project the physician factors are as follows: their demographic features, their work related features, education related features, drug information related features and drug promotion related features. The variables in drug prescriptions are drug expenses, daily drug expenses, days of medication, the highest price of the drugs used and the number of the different drugs used. Analysis of the use of prescription drugs was performed on NFMI(National Federation of Medical Insurance) 1994 medical expense claim data. Data on physicians' characteristics were collected by mailing surveys. Patients with secondary diseases were excluded. In this study, 388 adults with bronchitis, 1,038 children with bronchitis, 1,158 patients with gastritis, 369 patients with gastric ulcer were included. The older physicians tend to allow the lower drug costs: this explains that the older doctors who are more experienced less depend on the medicines. It can be also explained that doctors are likely to use the medicines that had been used for their intern and resident practice/training period. General practitioners give more intensive prescription compared to specialists. And specialists prescribed medicines to patients for longer period. The doctors' prescriptions for patients are largely affected by commercial sources. So objective and reliable sources for drug information is needed for patients' benefits. Physician factors explain better at the daily drug expenses, the drug price and the number of different drugs than days of medication. Gastric ulcer are better explained by the prescription model adopted in this study than other diseases.

  • PDF

Comparative Analysis of Stem Cell Research Policy Changes in UK, US, and South Korea: Application of Advocacy Coalition Framework Model (영국, 미국, 한국의 줄기세포연구에 관한 정책변동 비교 분석: Advocacy Coalition Framework 모형의 적용)

  • Bae, Green;Kang, Minah
    • Health Policy and Management
    • /
    • v.23 no.4
    • /
    • pp.314-325
    • /
    • 2013
  • Background: Stem cell research competition is accelerating globally since President Obama signed an executive order, repealing Bush-era policy that limited use of federal tax dollars for embryonic stem cell research. Methods: In this paper, we conducted a comparative analysis of stem cell research policy changes in three countries, including the Human Fertilisation Embryology Act (HFEA) of UK, executive order 13,505 (removing barriers to responsible scientific research involving human stem cells) of USA, and Bioethics and Safety Act of South Korea. Debates on stem cell research are based on conflicts of fundamental beliefs that exist in the supporting and opposing coalitions. We compared regional characteristics of the advocacy coalitions in three countries and presented various factors that might be related to the policy changes. Results: The UK government, parliament, and the HFEA have sought expert consultations and public opinions to establish guidelines. UK has made social consensus through continued discussion for a long time. US President's veto power was one strongest factors influencing policy. South Korean policy was influenced by public opinion and policy brokers. Also, South Korea has not made social consensus. UK had a strong leadership and strong adjustment of coalitions but US and South Korea had not. Dr. Hwang's scandal has had one of the greatest impacts on policy decision in South Korea. Conclusion: The power of public opinion was critical in all three countries. In particular, the influence of public opinion was noticeable in South Korea. Also it turned out that in US and South Korea, the presence of a policy broker who could pursue his or her goals was the most powerful factor among the advocacy coalition factors.

Modifications of a Grinding Machine Structure for the Improved Precision Machining (가공정도 향상을 위한 평면 연삭기의 설계 개선)

  • Shon, Jae-Yul;Ro, Seung-Hoon;Lim, Yo-Han;Lee, Jong-Hyung;Lee, Jae-Yul;Song, Eun-Seok;Lee, Tae-Hoon
    • Journal of the Korean Society of Industry Convergence
    • /
    • v.12 no.2
    • /
    • pp.99-105
    • /
    • 2009
  • Among a few items with world wide competitiveness are the semiconductor and the LCD. Grinding/polishing is the most significant process in manufacturing semiconductor wafers and LCD panels, the most critical quality of which is the precision rate of the machined surfaces. It is well known that the control of the vibrations is the major factor in maintaining superb machined surfaces. In this paper the dynamic properties of a grinding machine have been investigated through the frequency analysis test and the computer simulation to deduce ideas of design modifications for improved stability. The alterations have been applied to the simulation model, which is supposed to have identical dynamic property with the original structure, to identify the effects and to finally achieve the satisfactory level of stability. The result shows that the machine can have much improved stability with relatively simple design changes, and also can improve the surface quality of the products.

  • PDF

The Characteristics of Viscosity Behavior of EMC for Semi-conductor Encapsulant -The Prediction of Viscosity by Mooney Equation- (반도체 봉지제용 EMC의 점도거동 특성 연구 -Mooney식을 이용한 점도예측-)

  • Kim, In Beom;Bae, Doo Han;Lee, Myung Cheon;Lee, Euy Soo;Yun, Hyo Chang;Lim, Jong Chan
    • Applied Chemistry for Engineering
    • /
    • v.10 no.6
    • /
    • pp.949-953
    • /
    • 1999
  • Because epoxy molding compound(EMC) for semi-conductor encapsulants contains high concentrations of fillers, its flow behaviors are affected much by the concentrations and properties of those fillers. This paper reports the effects of a filler concentration, shape, size, and size distributions on the viscosity behavior of EMC(epoxy/silica). In addition, the prediction of viscosity behavior was performed using the Mooney equation. The maximum packing volume in the Mooney equation was calculated by Ouchiyama's packing model and Taguchi's optimization method, while the shpae factor was determined by fitting the experimental data. The results showed that the Mooney equation predicted the viscosity behavior of EMC very well.

  • PDF

Effects of Culinary and Foodservice Major Selection Motive and Work Value on the Major Satisfaction, Career Search Efficacy and Career Exploration Behavior (조리외식 전공만족도, 진로탐색효율 및 진로탐색행동에 미치는 전공선택동기와 직업가치관 효과)

  • Kim, Nam-Geun;Kim, Jong-Hyo
    • Korean journal of food and cookery science
    • /
    • v.32 no.6
    • /
    • pp.754-761
    • /
    • 2016
  • Purpose: This study was investigated the effects of culinary and foodservice major selection motive and work value on the major satisfaction, career search efficacy and career exploration behavior of college students. Methods: Survey comprising total 53 questions including 8 for major selection motive, 8 for work value, 6 for major satisfaction, 20 for career search efficacy, 5 for career exploration was distributed to 400 college students majoring in culinary or foodservice. Frequency analysis, factor analysis, correlation analysis, and multiple regression were conducted using SPSS Statistics (ver. 21.0). Organization of concept and analyses of the relationship between variables based on the advanced study and database is essential. Research model based on the theory and analysis of the extracted data was established; and subsequently, the proof relations between the variables were analysed. Results: The study results indicated that, only intrinsic work values among personal motivation and work values were significant. This is because personal motivation and intrinsic work values are related to subjects' aptitudes, interests, talents, and future professions when students choose their majors. Therefore, interest, abilities, achievement, high understanding, and satisfactory schooling are important factors. Conclusion: This study has newly expanded the research on career search behavior to include psychological factors and cognitive and attitudinal factors. We also determined competitive operations that enhance students' major satisfaction, career search efficiency, and career search behavior.

An Empirical Study about Medium and Small Enterprises Information System User Satisfaction (중소기업 정보시스템 사용자 만족도에 관한 실증적 연구)

  • Kim, Dong-I
    • Proceedings of the KAIS Fall Conference
    • /
    • 2008.11a
    • /
    • pp.484-487
    • /
    • 2008
  • This study investigates and analyzed to whole public offering listed company whether enterprise's integration information system exercises some influence on business users. Many medium and small enterprise introduce and operate new integrated system, but there was difficulty in Productivity Analysis that is real by unstableness of system, preservation and insufficiency of management control etc. Therefore, in this study, designed study model and research hypothesis laying stress on information strategy, system quality, information quality of information support agents to measure integration information system to relative stable enterprise. This study may become data that is useful in stable system introduction in various field of industry hereafter medium and small enterprises. This study Was construed by thing which degree that give influence of positive in user satisfaction as findings information system quality, quality of service, information support agents is good in study analysis is very high. The other side, information strategy was expose for factor that do not exert big influence on user's satisfaction, and got sequence that is affected in some degree if user satisfaction is high in details article.

  • PDF

Management Result Effecting Factors Through the Business Intelligence (비즈니스 인텔리전스 도입이 경영성과에 미치는 영향)

  • Kim, Hyun-Joon;Yang, Hae-Sool
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.9 no.2
    • /
    • pp.431-448
    • /
    • 2008
  • The change of management paradigm is that information technology change according to technology evolution at present is applied to corporate management, is that management level must be adapted to uncertainty management environment with activity and be made decision based on analyzed real time information through information system. This produces the effective target achievement and efficiency business productivity guarantee. At the present day, importation of business intelligence like enterprise information system has been the essential factor in business activities. Therefore, It is very important to give lessons the enterprises for building the business intelligence selecting the major success factors of more influence to managing results. In this paper, to authorize the research model and research constructions through theory study of literatures and surveying statics analysis prove the relational influences among the influencing factors related business intelligence system buliding.