• Transactions of the Korean Society of Mechanical Engineers
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• v.10 no.1
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• pp.25-33
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• 1986

In this paper, the frontal method based elastic-plastic F.E.M. program for mini-computer was developed. Since, the executable source program size was restricted by the system core memory size on the mini-computer, the active variables were memorized by the element base and the nonactive varables were memorized to the external disc file. The active variables of the finally developed program were reduced enough to execute about 1,000 freedom finite element on the mini-computer on which available variables were restricted as 32,767 integers. A modified CT fracture test specimen was examined to test the developed program. The calculated results were compared with experimental results concerning on the crack tip plastic deformation zone. Recrystallization technique was adopted to visualize the intensive plastic deformation regions. The Von-Mises criterion based calculation results were well agreed with the experimental results in the intensive plastic region which was over than 2% offset strain. The F.E.M. results using the developed program were well agreed with the theoritical plastic boundary which was calculated by the stress intensity factor as r$_{p}$=(K$_{1}$$^{2}$/2.pi..sigma.$_{y}$$^{2}$).f(.theta.).).).

• Journal of Preventive Medicine and Public Health
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• v.43 no.4
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• pp.330-340
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• 2010

Objectives: This study aims to evaluate and explain the socioeconomic inequalities of all-cause mortality after breast cancer surgery in South Korea. Methods: This population based study included all 8868 females who underwent radical mastectomy for breast cancer between January 2002 and June 2003. Follow-up for mortality continued from January 2002 to June 2006. The patients were divided into 4 socioeconomic classes according to their socioeconomic status as defined by the National Health Insurance contribution rate. The relationship between socioeconomic status and all-cause mortality after breast cancer surgery was assessed using the Cox proportional hazards model with adjusting for age, the Charlson’s index score, emergency hospitalization, the type of hospital and the hospital ownership. Results: Those in the lowest socioeconomic status group had a significantly higher hazard ratio of 2.09 (95% CI =1.50 - 2.91) compared with those in the highest socioeconomic group after controlling for all the identifiable confounding variables. For allcause mortality after radical mastectomy, all the other income groups showed significantly higher 3-year mortality rates than did the highest income group. Conclusions: The socioeconomic status of breast cancer patients should be considered as an independent prognostic factor that affects all-cause mortality after radical mastectomy, and this is possibly due to a delayed diagnosis, limited access or minimal treatment leading to higher mortality. This study may provide tangible support to intensify surveillance and treatment for breast cancer among low socioeconomic class women.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.13 no.3
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• pp.6-14
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• 2014

Touch panels are widely used in the modern display industry as the cover glass of smart mobile phones and tablet PCs. Glass cutting machines are commonly used to cut the panels into their proper sizes. Vibration of these glass cutting machines is assumed to be the main factor leading to the creation of burrs, notches, cracks, scratches and chips on the cut surfaces, eventually causing defects of the cover glass. In this study, the vibrations of a glass cutting machine used for the shearing of cover glass components were analyzed through an experiment and a computer simulation. The structural properties leading to vibration were also analyzed in an effort to determine design alterations which can suppress these vibrations. Moreover, each design alteration was applied to a computer simulation model to determine the effect of different alteration on suppressing vibration. The results show that simple design alterations can substantially suppress vibrations of glass cutting machines.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.10
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• pp.963-970
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• 2015

Laminate structures are used in the automobile, aerospace, and display industries. The advantages of fiber metal laminates are well known. Fiber metal laminates are useful for reducing the weight and improving impact resistance . However, currently, the mechanical properties of fiber metal laminates are not derived. In this paper, we use thickness as a factor for comparing the properties of laminates of various thickness combinations. The properties fiber metal laminates are analyzed using design of experiments. In addition, the finite element method is used to analyze elastic and plastic strains of fiber metal laminates and aluminum plates. The final goal of this paper is to find a suitable finite element model of fiber metal laminates under bending.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.38 no.5
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• pp.373-380
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• 2014

Film flows applied to shell-and-tube heat exchangers in various industrial fields have been studied for a long time. One boundary of the film flow interfaces with a fixed wall, and the other boundary interfaces with a gaseous region. Thus, the flows become so unstable that wavy behaviors are generated on free surfaces as the film Reynolds number increases. First, high-amplitude solitary waves are detected in a low Reynolds number laminar region; then, the waves transit to a low-amplitude, high frequency ripple in a turbulent region. Film thickness is the most significant factor governing heat transfer. Since the wave accompanied in the film flow results in temporal and spatial variations in film thickness, it can be of importance for numerically predicting the film's wavy behavior. In this study, various turbulent models are applied for predicting low-amplitude ripple flows in turbulent regions. The results are compared with existing experimental results, and finally, the applied turbulent models are appraised in from the viewpoint of wavy behaviors.

• Korean journal of food and cookery science
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• v.22 no.3 s.93
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• pp.259-269
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• 2006

The purposes of this study were to measure the correlation between leadership style and job satisfaction in family restaurants, and to compare the effectiveness of two different styles of leadership: transformational and transactional. The questionnaire used in this study was designed to measure all variables in the research model, and was made two kinds for employees and for managers. It was distributed to 550 employees and 12 managers in 16 stores of 4 family restaurants, from September 10 to October 7, 2004. A total of 303 usable employees' questionnaires were received, giving a 55.0% response rate, and all of managers responded. Statistical data analysis was completed using SPSS Win(11.0) for the following analyses: descriptive, reliability, factor, ANOVA, correlation and cluster. The results were as follows. First, the most influential leader was the senior staff in most of the hierarchies that were studied. Second, transformational leadership had a positive correlation with job satisfaction for family restaurant employees, while transactional leadership had a negative correlation. Third, using cluster analysis, four leadership groups were identified: transformational(44%), transactional(29%), a combination of both styles(4%), and unidentifiable style(23%). Fourth the transformational leadership group produced e highest rates job satisfaction for family restaurant employees. The transactional leadership group produced the lowest job satisfaction. According to the results, the most reasonable leadership style in family restaurants is transformational leadership.

• Korean Journal of Adult Nursing
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• v.29 no.1
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• pp.41-50
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• 2017

Purpose: The purpose of this study was to identify and compare the factors influencing attitude toward one's own aging among Korean middle-aged adults and the elderly. Methods: A cross sectional study was performed with a total sample of 70 middle-aged adults and 64 elderly reside in two metropolitan areas. Data were collected from August 2015 to November 2015 using the Perceived Health Status Scale, the Health Locus of Control Scale and the Attitude Toward own Aging (ATOA) Scale. The statistics used include percentage, t-test, Pearson's correlation coefficient, and multiple regression. Results: Mean age for each age group were about 52 and 76 years old for middle-aged adults and the elderly respectively. A considerable proportion of all participants reported a negative attitude toward aging. Perceived health status was the common factor influencing attitude toward one's own aging in both age groups. Middle-aged adults identified presence of chronic illness and internal health locus of control as important factors. In contrast, the elderly reported that education and others-dependent health locus of control such as powerful others had a significant impact on ATOA. Each regression model explained 31% and 55% of the total variance of ATOA among middle-aged adults and among the elderly. Conclusion: Both middle-aged adults and the elderly with low perceived health status are at risk of negative ATOA's. The type health locus of control need to be identified and utilized based on individuals' tendency to improve positive ATOA. That is, middle-aged adults might need reinforcement of their self-will whereas the elderly might need enhancement of social support and network of family and healthcare providers.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1261-1264
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• 2016

Background: In breast cancer (BC), it has been suggested that nuclear overexpression of p53 protein might be an indicator of poor prognosis. The aim of the current study was to evaluate the expression of p53 BC in Kurdish women from the West of Iran and its correlation with other clinicopathology figures. Materials and Methods: In the present retrospective study, 231 patients were investigated for estrogen receptor (ER) and progesterone receptor (PR) positivity, defined as ${\geq}10%$ positive tumor cells with nuclear staining. A binary logistic regression model was selected using Akaike Information Criteria (AIC) in stepwise selection for determination of important factors. Results: ER, PR, the human epidermal growth factor receptor 2 (HER2) and p53 were positive in 58.4%, 55.4%, 59.7% and 45% of cases, respectively. Ki67 index was divided into two groups: 54.5% had Ki67<20% and 45.5% had Ki67 ${\geq}20%$. Of 214 patients, 137(64%) had lymph node metastasis and of 186 patients, 122(65.6%) had vascular invasion. Binary logistic regression analysis showed that there was inverse significant correlation between lymph node metastasis (P=0.008, OR 0.120 and 95%CI 0.025-0.574), ER status (P=0.006, OR 0.080, 95%CI 0.014-0.477) and a direct correlation between HER2 (P=005, OR 3.047, 95%CI 1.407-6.599) with the expression of p53. Conclusions: As in a number of studies, expression of p53 had a inverse correlation with lymph node metastasis and ER status and also a direct correlation with HER2 status. Also, p53-positivity is more likely in triple negative BC compared to other subtypes.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3977-3982
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• 2012

Inhibitors of histone deacetylase activity are emerging as a potentially important new class of anticancer agents. In this study, we assessed the anticancer effects of valproic acid (VPA) on ovarian cancer in vitro and in vivo. Cultured SKOV3 cells were treated by VPA with different concentrations and time, then the effects on cell growth, cell cycle, apoptosis, and related events were investigated. A human ovarian cancer model transplanted subcutaneously in nude mice was established, and the efficacy of VPA used alone and in combination with diammine dichloroplatinum (DDP) to inhibit the growth of tumors was also assessed. Proliferation of SKOV3 cells was inhibited by VPA in a dose and time dependent fashion. The cell cycle distribution changed one treatment with VPA, with decrease in the number of S-phase cells and increase in G1-phase. VPA could significantly inhibit the growth of the epithelial ovarian cancer SKOV3 cells in vivo without toxic side effects. Treatment with VPA combined with DDP demonstrated enhanced anticancer effects. The result of flow cytometry (FCM) indicated that after VPA in vitro and in vivo, the expression of E-cadherin was increased whereas vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) were decreased. This study suggests that VPA could be a novel attractive agent for treatment of ovarian cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7665-7671
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• 2014

Objectives: The association between body mass index (BMI) and ovarian cancer risk is unclear and requires further investigation. The present meta-analysis was conducted to assess the effect of overweight and obesity on ovarian cancer risk in the premenopausal and postmenopausal periods. Data sources: Major electronic databases were searched until February 2014 including Medline and Scopus. Reference lists and relevant conference databases were searched and the authors were contacted for additional unpublished references. Review Methods: All cohort and case-control studies addressing the effect of BMI on ovarian cancer were included, irrespective of publication date and language. The effect measure of choice was risk ratio (RR) for cohort studies and odds ratio (OR) for case-control studies. The results were reported using a random effects model with 95% confidence intervals (CIs). Results: Of 3,776 retrieved studies, 19 were ultimately analyzed including 10 cohort studies involving 29,237,219 person-years and 9 case-control studies involving 96,965 people. The results of both cohort and case-control studies showed being overweight and obesity increased the risk of ovarian cancer compared to women with normal weight during both premenopausal and postmenopausal periods: RR=1.08 (95%CI: 0.97, 1.19) and OR=1.26 (95%CI: 0.97, 1.63) for overweight and RR=1.27 (95%CI: 1.16, 1.38) and OR=1.26 (95%CI: 1.06, 1.50) for obesity. Conclusions: There is sufficient evidence that an increase in BMI can increase the risk of ovarian cancer regardless of the menopausal status, mimicking a dose-response relationship although the association is not very strong.