• Culinary science and hospitality research
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• v.16 no.3
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• pp.147-160
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• 2010

This study aims to analyze the effect of emotional response from dining out experience on satisfaction after dining out based on the customers who have visited a luxurious Korean restaurant. For this study, it designed a research model through literary research and derived hypotheses. For the empirical analysis, 250 copies of the questionnaire using the self-administered method were distributed and 230(94%) copies were collected. Among them, 220(88%) copies were used for the analysis. SPSS WIN Version 12.0 statistical package program was used for the analysis of data processing, the frequency analysis, reliability analysis and factor analysis were operated, and the hypothesis testing was verified by the regression analysis. The results of the analyses are as follows. For the hypothesis that "the dining-out consumption pattern will have a significant effect on the emotional response," it was verified that the style which pursues health and the style which is loyal to relationships had significant effects on pleasure while the style which pursues rest didn't. Also, the style which pursues health and the style which is loyal to relationships had significant effects on arousal while the style which pursues rest didn't. For the hypothesis that "emotional response will have a significant effect on satisfaction," it was verified that pleasure and simulation had significant effects on satisfaction. As a result of the study, the current dining-out consumption pattern is changed from the purpose of having meals for the biological needs in the past to considering emotional response such as preferred taste or mood.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.3
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• pp.349-354
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• 2014

Elevation of intracellular calcium ($Ca^{{+}{+}}$) triggers degranulation of mast cells by bypassing receptor activation. Flos Sophora japonica L. has been used as a natural dying source and has been reported to have biological activities such as anti-inflammatory and anti-allergic effects through $Fc{\varepsilon}RI$ and IgE crosslinking. In the present investigation, we report the regulatory effect of ethanolic extract of Flos Sophora japonica L. (S.F) on allergic mediators produced by $Ca^{{+}{+}}$ ionophore activation in mast cells. S.F significantly inhibited calcium ionophore (A23187)-induced interleukin (IL)-4 and tumor necrosis factor (TNF)-${\alpha}$ production as well as mast cell degranulation. Furthermore, administration of S.F suppressed allergic reactions in a 2,4-dinitrofluorobenzene (DNFB)-induced allergic dermatitis mouse model. Both oral administration and ear painting using 50 mg/kg of S.F significantly reduced levels of cytokines such as IL-4, TNF, and interferon-${\gamma}$ in ear tissues compared to the DNFB alone-treated group. Serum IgE level in the S.F-treated group also decreased compared to the DNFB alone-treated group. Weights of spleens and lymph nodes in the S.F-treated groups also decreased compared to the control group. Considering the data, we conclude that S.F mediates its anti-allergic effects not only through $Fc{\varepsilon}RI$ stimulation but also $Ca^{{+}{+}}$ influx in mast cells.

• Journal of Yeungnam Medical Science
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• v.23 no.2
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• pp.193-204
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• 2006

Purpose: Various postoperative adjuvant chemotherapy regimens have been proposed for the patients with advanced gastric cancer. The majority of clinical trials have shown no significant difference in the survival benefit. The aim of this study was to compare the survival rates of postoperative adjuvant chemotherapies used in stage III gastric cancer patients who received curative gastrectomy. Materials and Methods: Between 1990 and 1999, a survival analysis was performed in 260 patients who received curative gastric resection and postoperative adjuvant chemotherapy. The patients were divided into four groups according to the chemotherapeutic regimens received. The groups were: the F group: furtulon alone, FM group: furtulon and mitomycin, FAM group: 5-FU, adriamycin and mitomycin, FLEP group: 5-FU, leucovorin, etoposide and cisplatin. The survival rates were analyzed using the Kaplan-Meier method and the Cox proportional hazards model. Results: There were no differences among the groups of patients with regard to tumor characteristics except for lymph node metastasis and the ratio of metastasis to lymph nodes. In the FLEP group, the ratio of metastasis to lymph nodes was higher than in the other groups. The five and ten year survival rates of F, FM, FAM and FLEP were 51.9%, 28.9%, 59.5%, 49.8%, 66.1%, 57.4% and 30.0%, 27.5%, respectively. The univariate analysis showed that age, Borrmann type, lymph node metastasis, ratio of metastasis to lymph nodes, postoperative adjuvant chemotherapy and recurrence were significant factors for survival. For the multivariate analysis, recurrence, age, Borrmann type, ratio of lymph node metastasis and lymph node dissection were independent prognostic factors; however, the postoperative adjuvant chemotherapy was not an independent prognostic factor. Conclusion: The FAM regimen was the most beneficial postoperative adjuvant chemotherapy for improved survival rates; the FM regimen was the second and the FLEP regimen was the last. In order to determine the effectiveness of postoperative adjuvant chemotherapy in stage III gastric cancer, well designed prospective studies including a surgery only group will be needed.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.323-335
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• 2016

Breast cancer risk assessment has developed during years and evaluation of genetic factor affecting risk of breast cancer is an important component of this risk assessment. The aim of this meta-analysis was to investigate the role of XRCC1 polymorphisms (Arg194Trp, Arg280His and Arg399Gln) in risk of breast cancer among different population and categories of menopausal status.PubMed, Medline, Web of Science, and PubMed Central were systematically searched to identify studies evaluating association between breast cancer and XRCC1 gene polymorphisms (Arg194Trp, Arg280His and Arg399Gln). Two authors independently extracted required information. Odds Ratios were pooled for four genetic inheritance models using both fixed and the DerSimonian and Laird random-effect models. Egger's test and contour-enhanced funnel plot was used to evaluate publication bias and small study effect. Additional subgroup analysis was performed for menopausal status, ethnicity, and source of controls. After evaluation and applying inclusion criteria on extracted studies, fifty three studies were included in this meta-analysis. For polymorphisms of Arg194Trp and Arg280His, no significant association was observed in all genetic models. Arg194Trp had a protective effect in post-menopausal status only in homozygote model (OR=0.57 [0.37-0.88]). Arg399Gln showed significant association with breast cancer in homozygote (OR=1.21 [1.10-1.34]), dominant (OR=1.09 [1.03-1.15]) and recessive (OR=1.21 [1.09- 1.35]) genetic models. Arg399Gln was associated with higher risk in post-menopausal status for homozygote and heterozygote models. Our findings suggest that XRCC1 gene polymorphisms modify breast cancer risk in different populations and different categories of menopausal status.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.5
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• pp.113-127
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• 2020

Based on the social exchange theory and innovation diffusion theory, this study is to identify the correlation between factors influencing investor's funding intention in crowdfunding and to analyze moderating effect of trust in the relationship of shared value, communication and individual innovation. The purpose of this study is to consider the funding trends of crowdfunding investors from a personal point of view through the results of the study and to help fundraiser of crowdfunding establish specifically strategies for financing. In order to conduct empirical analysis, an online survey was conducted on people who had participated in crowdfunding, and a total of 228 questionnaires were collected and a total of 186 responses were finally analyzed, excluding outliers. For data analysis, structural equation model analysis was conducted using SPSS 26.0 and Smart PLS 3.0. The results of this study showed that shared value in the relationship between fundraiser and investors has a significant effect on the perceived risk. High level of communication between fundraiser and investors showed positive effects on the level of commitment of the crowdfunding project and the innovation of the individual investor. And commitment had a positive effect on the funding intention. According to the results of this research, trust has moderating effect only in relationship between shared value and perceived risk. It is significant that investors share the value of fundraiser together is a motivation factor to fund in crowdfunding and an opportunity to recognize the risk. Through this study, it is expected to utilize them in establishing strategies for start-ups and marketing plans to raise funds through crowdfunding and to empirically identify factors influencing the funding intention through individual levels of crowdfunding investors.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.5
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• pp.51-63
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• 2020

In this study, the objective of the study was to verify how college students' entourage and transformational leadership can affect employment and entrepreneurship perception. In addition, with the coronavirus infection, which has a widespread global impact over the past few months, we want to see how the social issue of pandemic affects the personal characteristics of college students and their perceptions of employment and entrepreneurship. Research Results University students with high entrepreneurship and transformational leadership perceived the social issue of the Corona 19 pandemic as a crisis, which is comparable to the economic crisis, and rather than cringe, adapting to the shift of a new paradigm, new job opportunities or opportunities for entrepreneurship It was found to be an opportunity to recognize as. As the untact society is expected to become a new normal, securing new employment and entrepreneurship opportunities is emerging as an important factor through cultivation of entrustment and transformational leadership. The results of this study are based on the need for practical education on entrepreneurship and transformational leadership, such as creating a business model to strengthen the ability to'explore opportunities' to explore opportunities in crisis for potential entrepreneurs and college students with potential employment potential. Is suggesting.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.36 no.2
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• pp.307-315
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• 2016

Many countries are trying to reduce a greenhouse gas to step up their fight against climate change. There are many studies related to building only for reducing a greenhouse gas in construction area but studies related to reducing a comprehensive environmental load including various pollutants that affects the global environment are lacking. This study aims to analyse the characteristics of environmental load by work type for tunnel projects. Analysis showed that seven work types, including lining concrete, shotcrete, tunnel portal and open-cut tunnel work, etc., are representative works generated environmental load. These seven works represent 89.22 percent of total environmental load. In addition, comparison results of environmental load per tunnel's length by work type showed that a major factor of environmental load is caused by a tunnel portal and open-cut tunnel work with relatively short length (excavation length). And lining concrete and shotcrete work are larger than any other environmental load with tunnel's total length. It is expected that the result of this study will be used to make a estimation model for environmental load using approximate quantity survey of representative work types in the early stage of tunnel design. And it will be play a considerable role in establishing of environment management plan for sustainable infrastructure construction.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.2
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• pp.397-405
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• 2015

In the past, expressways focused on mobility. However, the paradigm of expressways fuction today has been changed from fast expressways to safe expressways as people's quality of living and consciousness level heightened. In 2012, 3,550 traffic accidents occurred on expressways and 371 people died. The fatality rate of traffic accidents on expressways is almost twice that on general national roads. This study developed accident forecast models (safety performance functions) based on the number of traffic accidents and traffic volumes on six major lines on expressways. It is difficult to forecast safety performance functions for each expressway line because the lines and the scales of expressways are different from each other; therefore, integrated safety performance functions of six lines were determined first, and the coefficients, which can correct the traffic accidents on each line, were calculated. It is believed that this study will contribute in the safer management of expressways by being used as basic information in the establishment of traffic safety strategies for each expressway line in prevention of traffic accidents. Moreover, more studies would be required in the future, which would suggest reliable accident forecasts by calculating correction coefficients by line through integrated models by groups dependent on the characteristics of each line.

• Geomechanics and Engineering
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• v.14 no.1
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• pp.99-105
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• 2018

Soils are generally classified as fine-grained or coarse-grained depending on the percentage content of the primary constituents. In reality, soils are actually made up of mixed and composite constituents. Soils primarily classified as fine-grained, still consists of a range of coarse particles as secondary constituents in between 0% to 50%. A laboratory scale model test was conducted to investigate the influence of coarse particles on the physical (e.g., density, water content, and void ratio) and mechanical (e.g., quick undrained shear strength) properties of primarily classified fine-grained cohesive soils. Pure kaolinite clay and sand-mixed kaolinite soil (e.g., sand content: 10%, 20%, and 30%) having various water contents (60%, 65%, and 70%) were preconsolidated at different stress levels (0, 13, 17.5, 22 kPa). The quick undrained shear strength properties were determined using the conventional Static Cone Penetration Test (SCPT) method and the new Fall Cone Test (FCT) method. The corresponding void ratios and densities with respect to the quick undrained shear strength were also observed. Correlations of the physical properties and quick undrained shear strengths derived from the SCPT and FCT were also established. Comparison of results showed a significant relationship between the two methods. From the results of FCT and SCPT, there is a decreasing trend of quick undrained shear strength, strength increase ratio ($S_u/P_o$), and void ratio (e) as the sand content is increased. The quick undrained shear strength generally decreases with increased water content. For the same water content, increasing the sand content resulted to a decrease in quick undrained shear strength due to reduced adhesion, and also, resulted to an increase in density. Similarly, it is observed that the change in density is distinctively noticeable at sand content greater than 20%. However, for sand content lower than 10%, there is minimal change in density with respect to water content. In general, the results showed a decrease in quick undrained shear strength for soils with higher amounts of sand content. Therefore, as the soil adhesion is reduced, the cone penetration resistances of the FCT and SCPT reflects internal friction and density of sand in the total shear strength.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.6
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• pp.772-784
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• 2012

Marker-assisted gene pyramiding aims to produce individuals with superior economic traits according to the optimal breeding scheme which involves selecting a series of favorite target alleles after cross of base populations and pyramiding them into a single genotype. Inspired by the science of evolutionary computation, we used the metaphor of hill-climbing to model the dynamic behavior of gene pyramiding. In consideration of the traditional cross program of animals along with the features of animal segregating populations, four types of cross programs and two types of selection strategies for gene pyramiding are performed from a practical perspective. Two population cross for pyramiding two genes (denoted II), three population cascading cross for pyramiding three genes(denoted III), four population symmetry (denoted IIII-S) and cascading cross for pyramiding four genes (denoted IIII-C), and various schemes (denoted cross program-A-E) are designed for each cross program given different levels of initial favorite allele frequencies, base population sizes and trait heritabilities. The process of gene pyramiding breeding for various schemes are simulated and compared based on the population hamming distance, average superior genotype frequencies and average phenotypic values. By simulation, the results show that the larger base population size and the higher the initial favorite allele frequency the higher the efficiency of gene pyramiding. Parents cross order is shown to be the most important factor in a cascading cross, but has no significant influence on the symmetric cross. The results also show that genotypic selection strategy is superior to phenotypic selection in accelerating gene pyramiding. Moreover, the method and corresponding software was used to compare different cross schemes and selection strategies.