• Journal of the Korean Association of Geographic Information Studies
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• v.16 no.3
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• pp.193-210
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• 2013

This study aims to assess the slope stability variation of Jeollabuk-do drainage areas by RCM model outputs based on A1B climate change scenario and infinite slope stability model based on the specific catchment area concept. For this objective, we downscaled RCM data in time and space: from watershed scale to rain gauge scale in space and from monthly data to daily data in time and also developed the GIS-based infinite slope stability model based on the concept of specific catchment area to calculate spatially-distributed wetness index. For model parameterization, topographic, geologic, forestry digital map were used and model parameters were set up in format of grid cells($90m{\times}90m$). Finally, we applied the future daily rainfall data to the infinite slope stability model and then assess slope stability variation under the climate change scenario. This research consists of two papers: the first paper focuses on the methodologies of climate change scenario preparation and infinite slope stability model development.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.14 no.3
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• pp.299-308
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• 2001

This paper presents the three-dimensional (3-D) study of the natural vibration of cantilevered laminated composite plates. The Ritz method is used to obtain stationary values of the associated Lagrangian functional with displacements approximated by mathematically complete polynomials satisfying the boundary conditions at the clamped edge exactly. The accuracy of the 3-D model is established through a convergence study of non-dimensional frequencies followed by a comparison of the converged 3-D solutions with analytical and experimental findings in the existing literature. A wide scope of 3-D frequency results explain the influence of a number of geometrical and material parameters for cantilevered laminated plates, namely aspect ratio (a/b), width-to-thickness ratio (a/h), orthotropy of material, number of plies (NP), fiber orientation angle(θ), and stacking sequence.

• Journal of Acupuncture Research
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• v.24 no.2
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• pp.1-14
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• 2007

목적 : 이 연구는 Vipera lebetina turanica의 사독약침파(蛇毒藥鍼波)(Snake venom toxin, SVT)이 in vitro에서 $NF-{\kappa}B$의 활성억제와 apoptosis 관련 단백질의 발현 조절을 통하여 세포자멸사(Apoptosis)를 유도하는지 in vivo에서 또한 전립선 암세포주인 PC-3 세포의 성장을 억제하는지 살펴보고자 하였다. 방법 : SVT를 처리한 후 PC-3의 성장억제를 관찰하기 위해 WST-1 assay, CCK-8 assay를 시행하였고，Apoptosis evaluation에는 DAPI, TUNEL staining assay를 시행하였으며，Apoptosis regulatory proteins의 변화 관찰에는 western blot analysis를 시행하였고，apoptosis와 연관된 $NF-{\kappa}B$의 활성 변화를 관찰하기 위해 EMSA시행하였으며，SVT의 핵내이동을 관찰하기 위해 Immunofluorescence Staining, Confocal immunocytochemistry를 시행하였으며，전립암세포의 종양형성에는 흉선을 제거한 쥐에 Tumorigenecity study를 시행하였다. 결과 : PC-3 세포에 SVT를 처리한 후，전립선 암세포의 성장，Apoptosis의 유발，Apoptosis관련 단백질의 발현，$NF-{\kappa}B$의 활성，SVT의 PC-3세포 핵내 이동여부 및 흉선제거 후 PC-3 세포를 이식한 쥐의 종양형성과정에 미치는 영향을 관찰하여 다음과 같은 결과를 얻었다. 1. PC-3 세포에서 SVT를 처리한 후 세포성장이 억제되고，세포자멸사가 유도되며，조절인자인 p53, caspase-3, -9는 증가되었고，Bcl-2는 감소되었다. 2. PC-3 세포에서 SVT를 처리한 후 $NF-{\kappa}B$의 활성이 유의하게 감소되었다. 3. DAPI로 염색된 상태에서 SVT가 PC-3 세포의 핵내로 이통되는 것이 관찰되었다. 4. 흉선제거 후 전립선 암세포주를 이식한 쥐에서 SVT를 피내로 주입한 결과 전립선암의 크기와 무게가 유의하게 감소하였다. 결론 : 이상의 결과는 SVT가 $NF-{\kappa}B$의 활성 억제를 통하여 인간 전립선암세포주인 PC-3의 세포자멸사를 유발함으로써 증식억제 효과가 있음을 입증한 것이며，이를 재확인한 생체 연구에서의 긍정적인 결과는 향후 SVT의 전립선암의 예방과 치료에 대한 효과적인 치료제 개발에 초석이 될 것으로 기대된다.

• Korean Journal of Agricultural Science
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• v.43 no.4
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• pp.623-633
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• 2016

A total of 6,973 steer growth records of Hanwoo breeding bull's progeny test data collected from 1989 to 2015 were analyzed to identify the most appropriate growth curve among three growth curve models (Gompertz, Logistic and von Bertalanffy). The Gompertz growth curve model equation was $W_t=990.5e^{{-2.7479e}^{-0.00241t}}$, the Logistic growth curve model equation was $W_t=772(1+8.3314e^{-0.00475t})^{-1}$, and the von Bertalanffy growth curve model equation was $W_t=1,196.4(1-0.646e^{-0.00162t})^3$. The Gompertz model parameters A, b, and k were estimated to be $990.5{\pm}10.27$, $2.7479{\pm}0.0068$, and $0.00241{\pm}0.000028$, respectively. The inflection point age was estimated to be 421 days and the weight of inflection point was 365.3 kg. The Logistic model parameters A, b, and k were estimated to be $772.0{\pm}4.12$, $8.3314{\pm}0.0453$, and $0.00475{\pm}0.000033$, respectively. The inflection point age was estimated to be 445 days and the weight of inflection point was 385.0 kg. The von Bertalanffy model parameters A, b, and k were estimated to be $1196.4{\pm}18.39$, $0.646{\pm}0.0010$, and $0.00162{\pm}0.000027$, respectively. The inflection point age was estimated to be 405 days and the weight of inflection point was 352.0 kg. Mature body weight of the von Bertalanffy model was 1196.4 kg, the Gompertz model was 990.5 kg, and the Logistic model was 772.0 kg. The difference between actual and estimated weights was similar in the Logistic model and the von Bertalanffy model. The difference between market weight and estimated market weight was the lowest in the Gompertz model. The growth curve using the von Bertalanffy model showed the lowest mean square error.

• Food Science of Animal Resources
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• v.30 no.3
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• pp.487-494
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• 2010

Cooked pork can be easily contaminated with Staphylococcus aureus during carriage and serving after cooking. This study was performed to develop growth prediction models of S. aureus to assure the safety of cooked pork. The Baranyi and Gompertz primary predictive models were compared. These growth models for S. aureus in cooked pork were developed at storage temperatures of 5, 15, and $25^{\circ}C$. The specific growth rate (SGR) and lag time (LT) values were calculated. The Baranyi model, which displayed a $R^2$ of 0.98 and root mean square error (RMSE) of 0.27, was more compatible than the Gompertz model, which displayed 0.84 in both $R^2$ and RMSE. The Baranyi model was used to develop a response surface secondary model to indicate changes of LT and SGR values according to storage temperature. The compatibility of the developed model was confirmed by calculating $R^2$, $B_f$, $A_f$, and RMSE values as statistic parameters. At 5, 15 and $25^{\circ}C$, $R^2$ was 0.88, 0.99 and 0.99; RMSE was 0.11, 0.24 and 0.10; $B_f$ was 1.12, 1.02 and 1.03; and $A_f$ was 1.17, 1.03 and 1.03, respectively. The developed predictive growth model is suitable to predict the growth of S. aureus in cooked pork, and so has potential in the microbial risk assessment as an input value or model.

• Journal of Photoscience
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• v.3 no.1
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• pp.23-28
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• 1996

To investigate the structure and function of photosystem I, cartridge mutagenesis technique was used to inactivate the psaB gene of photosystem I. From the screen, many strains which have potential defects in photosystem I were generated. Biochemical analysis revealed that B2, one of the mutant, had a reduced amount of chlorophyll. Electron transfer activitx from photosystem II to photosystem I as oxygen uptake was the rate of 64 % of wild type. Also B2 showed a decreased photosystem I activity when measured by 77 K fluorescence emission spectrum. Particularly, immunodetection analysis showed that the B2 had reduced amount of PsaA/PsaB, but a normal range of PsaC and PsaD. Here we present a photoheterotrophic mutant for psaB gene as a unique model strain for future study of structural/functional relationship and biogenesis of photosystem I.

• Structural Engineering and Mechanics
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• v.5 no.3
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• pp.221-237
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• 1997

This paper presents a new uniaxial material model for rate-sensitive analysis addressing both the transient and steady-state responses. The new model adopts visco-plastic theory for the rate-sensitive response, and employs a three-parameter representation of the overstress as a function of the strain-rate. The third parameter is introduced in the new model to control its transient response characteristics, and to provide flexibility in fitting test data on the variation of overstress with strain-rate. Since the governing visco-plastic differential equation cannot be integrated analytically due to its inherent nonlinearity, a new single-step numerical integration procedure is proposed, which leads to high levels of accuracy almost independent of the size of the integration time-step. The new model is implemented within the nonlinear analysis program ADAPTIC, which is used to provide several verification examples and comparison with other experimental and numerical results. The companion paper extends the three-parameter model to trilinear static stress-strain relationships for steel and concrete, and presents application examples of the proposed models.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2004.11a
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• pp.269-274
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• 2004

Recent adoption of the generalized sensor model to IKONOS and Quickbird satellite imagery have promoted various research activities concerning alternative sensor models which can replace conventional physical sensor models. For example, there are the Rational Function Model(RFM), the Direct Linear Transform(DLT) and the polynomial transform. In this paper, the DLT model which uses just a few number of GCPs was suggested. To evaluate the accuracy of the proposed DLT model, the RFM using 35 GCPs and the bias compensation method(Fraser et al., 2003) were compared with it. Quantitative evaluation of 3B positioning results were performed with independent check points and the digital elevation models(DEMs). In result, a 1.9- to 2.2-m positioning accuracy was achieved for modeling and DEM accuracy is similar to the accuracy of the other model methods.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6959-6968
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• 2015

This study aims to update the supply-demand model of wood products(FOSMO-2013) and to forecast mid and long run supply and demand for each products. The subjects of the study include sawnwood, plywood, particle board, fiberboard(MDF), and pulp. The updated partial equilibrium model is composed of supply function, import demand function, demand function, price relation function. The long run outlooks of world prices of wood and wood products are imported from the results of Buongiorno(2012). This study also adopt Buongiorno's scenarios, which includes three scenarios of IPCC(A1B, A2, B2) and the other one with assumption of increasing fuelwood consumption of A1B scenario. The result says that the domestic productions of wood products are expecting to decrease while the imports of them increase even there are some differences among the products as well as scenarios.

• Proceedings of the IEEK Conference
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• 2001.06d
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• pp.61-64
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• 2001

This paper proposes an automatic method for generating and 3D draping the skirt 3D models. The method constructs a 3D basic model of the skirts using elliptic cylinder and generates the various skirt 3D models by controlling the ellipses of the basic model. B-Spline approximates the wrinkles around the ellipse for the various 3D draping changing according to designs and textiles. We make some real skirts and investigate appearances for their drapes. This paper simulates their appearances and obtains good results. Furthermore, adaptation of the skirt 3D model to a personal character implements realistic coordination of the various skirts.