• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.5707-5713
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• 2013

The purpose of this study was to identify the effect of organizational culture types of hospital and nursing experience on organizational citizenship behaviors of nurses that examined the fitness of a path model. The subject of this study were 368 nurses who were working at 3 hospitals. The data were collected by structured questionnaire from May 1 to June 28 of 2013. Data were analyzed using on SPSS Win 20.0 and AMOS 18.0 program. The results of this study organizational culture types of hospital and nursing experience explained 32% of the variance for organizational citizenship behaviors of nurses. Innovative-oriented organizational culture types of hospital were important factors for affecting organizational citizenship behaviors of nurses. Therefore the nurse manager must establish the strategies to improve who nurses' creative and innovative ideas accepted by the culture to change.

• Journal of Photoscience
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• v.4 no.2
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• pp.41-48
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• 1997

The plasma membrane and microsomes, isolated from the cells treated with hematoporphyrm derivative (HpD) for 1 and 24 h, accumulated the aggregated porphyrin. The quantity of aggregated porphyrin was same in the plasma membrane and microsomes after isolating them from cells treated with HpD for 1 h whereas the microsomes accumulated higher quantity of aggregated porphyrin when cells were treated with HpD for 24 h. Photodynamic action of aggregated porphyrin on plasma membrane and microsomes was investigated using lipid specific fluorescent probes: 1,6-diphenyl-1,3,5-hexatrine (DPH) and 1-(4-trimethylammonium), 6-diphenyl-1,3,5-hexatrine(TMA-DPH). The time dependent anisotropy of these probes in the membranes was measured and the decay of anisotropy was analyzed using wobbling in cone model. Upon irradiation both the plasma membrane and the microsomes showed an increase in the limiting anis~)tropy and order parameter and a decrease in the cone angle of the lipid probes. The increase in the limiting anisotropy was pronounced in membranes isolated from the cells treated with HpD for 24 h. Photoinduced change in the limiting anisotropy was dependent on the duration of incubation of cells with HpD before isolating the membranes. In both the membranes. the membrane core was affected more as compared to the outer leaflet. In addition to the structural changes, a decrease in Na$^+$-K$^+$-ATPase and NADPH cyt c reductase activity was also observed upon irradiation of HpD treated cells. Inhibition in NADPH cyt c reductase was more when cells were treated with HpD for 24 h, however, Na$^+$-K$^+$-ATPase activity did not depend on the duration of the treatment of cells with HpD before irradiation. Our results suggest that the extent of photoinduced perturbations in the membranes varies as a function of duration of the treatment of cells with HpD and the membrane core is more susceptible to the photodynamic action of aggregated porphyrin.

• Restorative Dentistry and Endodontics
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• v.22 no.1
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• pp.170-180
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• 1997

Cariogenicity of the bacteria is attributed to their binding capacity to the teeth. Bacterial attachment to oral surfaces is an essential step for colonization and subsequently infection. Therefore, it is conceivable that caries prevention can be achieved fundamentally by inhibition of bacterial attachment. The rationale for caries prevention through the use of sugar substitutes or limited use of sugar has been revealed. Among many sugar substitutes, xylitol has been shown to exhibit the most profound cariostatic effect, inhibiting glucose metabolism and possibly binding of mutans streptococci. The purpose of this study was to examine the effect of xylitol on binding of different species of oral bacteria. The effect of xylitol on binding of [$^3H$]-labeled oral bacteria to hydroxyapatite coated with human saliva(SHA) as a model for the pellicle-coated tooth surfaces was investigated. The strains of oral bacteria used in this study were A. viscosus T14V, A. viscosus WVU627, P. gingivaiis 2561, P. gingivalis A7Al-28, S. gordonii G9B, S. gordonii Challis, S. sobrinus 6715, S. mutans UA101, S. mutans KPSK -2, S. mutans T8, and S. mutans UA130. The obtained results were as follows: 1. P. gingivalis A7 Al-28, S. mutans UA130, S. mutans T8 grown with xylitol showed greater binding to SHA than the organism grown without xylitol. Among these, S. mutans T8 showed the greatest rate of increase in its binding to SHA ; 8-fold increase in its binding with xylitol. 2. S. mutans KPSK -2 grown with xylitol showed 2 times lesser binding to SHA than the organism grown without xylitol. 3. Binding ability of the remaining strains grown with xylitol to SHA was almost same as that of the organisms grown without xylitol. The overall results suggest that use of xylitol in the oral cavity may affect the complex oral bacterial ecosystem.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.1
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• pp.13-29
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• 2020

Objectives This study was performed to decide the bone union effect of Hwaweo-jeon on tibia fractured mice. Methods In this study, laboratory experiments were implemented by the stage of in vitro and in vivo. In in vitro, MC3T3-E1 cells were treated with various concentration of Hwaweo-jeon extract (HWJ). To investigate effect of HWJ for osteoblast, relative mRNA expression of 5 substances (alkaline phosphatase [ALP], runt-related transcription factor 2 [Runx2], osteocalcin [OCN], osterix [OSX] and collagen type II alpha 1 chain [Col2a1]) was used as a marker of osteogenesis. In order to determine HWJ's effect for fracture healing, relative gene expression level of ALP, Runx2, OCN, OSX and Col2a1 were used to find out the influence to osteoblast. Furthermore, receptor activator of nuclear factor kappa-B ligand and osteoprotegerin relative mRNA expression were used to estimate the impact to osteoclast. Also, X-ray was used for the purpose of identifying bone union in tibia-fracture mouse model. Results In in vitro experiment, most part of relative mRNA expression were increased compared to control group. In in vivo and in vitro experiment, HWJ induced osteoblast activitation by verifying relative mRNA expression of 5 substances. And in vivo experiment, we can also identify that HWJ triggered osteoclast activation during early stage of tibia fracture. Furthermore, X-ray pictures show noticeable recovery of tibia fracture. Conclusions HWJ extract promotes bone union by facilitating the osteoblast. But, HWJ may occur liver & kidney toxicity over specific concentration. Therefore, when HWJ is applied to human body, doctors have to follow up the liver function test & renal function test of patient.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.10B
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• pp.911-918
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• 2008

In this paper, we propose new cell structures using multi-hop Relay Station(RS) based on IEEE802.16j in Narrow-Beam Trisector Cell (NBTC) and Wide-Beam Trisector Cell (WBTC), which are two methods for cell sectorization using 3-sector directional antennas. Then, we analyze our proposed structures compared with the existing system which does not use any RS about the numbers of optimized Base Station (BS) and multi-hop relay, the extended BS coverage, and the deployment cost according to the traffic density using optimization model. According to the results, we know the reduction of total deployment cost of the proposed systems and that WBTC is suitable when the traffic density is high and NBTC is suitable when the traffic density is low in our proposed multi-hop based NBTC and WBTC structures.

• Structural Engineering and Mechanics
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• v.59 no.3
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• pp.503-526
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• 2016

In-plane and out-of-plane free vibration analysis of Timoshenko curved beams is addressed based on the isogeometric method, and an effective scheme to avoid numerical locking in both of the two patterns is proposed in this paper. The isogeometric computational model takes into account the effects of shear deformation, rotary inertia and axis extensibility of curved beams, and is applicable for uniform circular beams, and more complicated variable curvature and cross-section beams as illustrated by numerical examples. Meanwhile, it is shown that, the $C^{p-1}$-continuous NURBS elements remarkably have higher accuracy than the finite elements with the same number of degrees of freedom. Nevertheless, for in-plane or out-of-plane vibration analysis of Timoshenko curved beams, the NURBS-based isogeometric method also exhibits locking effect to some extent. To eliminate numerical locking, the selective reduced one-point integration and $\bar{B}$ projection element based on stiffness ratio is devised to achieve locking free analysis for in-plane and out-of-plane models, respectively. The suggested integral schemes for moderately slender models obtain accurate results in both dominated and non-dominated regions of locking effect. Moreover, this strategy is effective for beam structures with different slenderness. Finally, the influence factors of structural parameters of curved beams on their natural frequency are scrutinized.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1704-1710
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• 2010

The structure of a 2D grid-like copper(II) complex [Cu$(NCO)_2$(pyz)](pyz=pyrazine) (1) consists of 1D chains of Cu-pyz units connected by double end-on (EO) cyanato bridges. Each Cu(II) ion has a distorted octahedral coordination, completed by the four EO cyanato and two pyrazine ligands. Magnetic interactions through EO cyanato and pyrazine bridges in 1 are discussed on the basis of DFT broken-symmetry calculations at the B3LYP level. For model dicopper(II) complexes I (bridged by cyanato) and II (bridged by pyrazine), electronic structure calculations reproduce very well the experimental couplings for the S = 1/2 ferromagnetic and antiferromagnetic exchange-coupled 2D system: the calculated exchange parameters J are +1.25 $cm^{-1}$ and -3.07 $cm^{-1}$ for I and II, respectively. The $\sigma$ orbital interactions between the Cu $x^2-y^2$ magnetic orbitals and the nitrogen lone-pair orbitals of pyrazine are analyzed from the viewpoint of through-bond interaction. The energy splitting of 0.106 eV between two SOMOs indicates that the superexchange interaction should be antiferromagnetic in II. On the other hand, there are no bridging orbitals that efficiently connect the two copper(II) magnetic orbitals in I because the HOMOs of the basal-apical NCO bridge do not play a role in the formation of overlap interaction pathway. The energy separation in the pair of SOMOs of I is calculated to be very small (0.054 eV). This result is consistent with the occurrence of weakly ferromagnetic properties in I.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.21 no.9
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• pp.1674-1680
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• 2017

In this paper, an embedded system for face authentication, which exploits high-dimensional local binary pattern (LBP) descriptor and joint Bayesian algorithm, is proposed. We also present a feasible embedded system for the proposed algorithm implemented with a Raspberry Pi 3 model B. Computer simulation for performance evaluation of the presented face authentication algorithm is carried out using a face database of 500 persons. The face data of a person consist of 2 images, one for training and the other for test. As performance measures, we exploit score distribution and face authentication time with respect to the dimensions of principal component analysis (PCA). As a result, it is confirmed that an embedded system having a good face authentication performance can be implemented with a relatively low cost under an optimized embedded environment.

• Bulletin of the Korean Chemical Society
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• v.25 no.10
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• pp.1477-1483
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• 2004

We present the tandem mass spectrometry applications carried out to elucidate the coordination structure of Zn(II) bound lysine ternary complexes, $(Zn+Lys+Lys-H)^+$, which is a good model system to represent a simple (metallo)enzyme-substrate complex (ES). In particular, experimental efforts were focused on revealing the involvement of a lysine side chain ${\varepsilon}$-amino group in the coordination of $Zn^{2+}$ divalent ions. MS/MS fragmentation pattern showed that all the oxygen species within a complex fell off in the form of $H_2O$ in contrast to those of other ternary complexes containing amino acids with simple side chains (4-coordinate geometries, Figure 1a), suggesting that the lysine complexes have different coordination structures from the others. The participation of a lysine basic side chain in the coordination of Zn(II) was experimentally evidenced in MS/MS for $N{\varepsilon}$-Acetyl-L-Lys Zn(II) complexes with acetyl protection groups as well as in MS/MS for the ternary complexes with one $NH_3$ loss, $(Zn+Lys+Lys-NH_3-H)^+$. Detailed structures were predicted using ab initio calculations on $(Zn+Lys+Lys-H)^+$ isomers with 4-, 5-, and 6-coordinate structures. A zwitterionic 4-coordinate complex (Figure 7d) and a 5-coordinate structure with distorted bipyramidal geometry (Figure 7b) are found to be most plausible in terms of energy stability and compatibility with the experimental observations, respectively.

• Journal of Korean Tunnelling and Underground Space Association
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• v.19 no.5
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• pp.717-732
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• 2017

Recently, the construction of underground structure such as a double-deck tunnel is increasing to manage rapid growth of roadway traffic volume. Double-deck tunnel includes middle slab to separate upper and lower road inside, and various sources affect the dynamic behaviour of middle slab due to dynamic loading of vehicle. Therefore, it is important to investigate the dynamic response of middle slab precisely to apply it to design and analysis of double-deck tunnel. In this study, dynamic analysis model of middle slab considering structural type, design velocity, vehicle load, and surface roughness, etc. is built. 3-dimensional dynamic analysis is performed to assess dynamic response of middle slab. Consequently, Dynamic Magnification Factor which represents dynamic response of middle slab shows maximum in case of elastomeric bearings (EB) and average roughness (Grade C). It is also expected that dynamic response can be reduced under the condition of good roughness (Grade B) and fixed bearings (FB).