• Journal of the Korean GEO-environmental Society
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• v.2 no.1
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• pp.37-56
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• 2001

As a preliminary study to establish fracture network model in crystalline rocks, detail investigation on fracture characteristics were performed. Five fracture sets were determined on the basis of regional survey of geological structures and fractures on outcrops. Among the fracture sets, S1 set has the highest density and longest trace length of fractures which was identified on surface in the study area. S4 and S5 sets are composed of foliations and foliation parallel shear joints of gneisses, which are very important sets at the aspect of weighting of fracture length. For characterization of subsurface fractures, detail core logging was performed to identify fractures and fracture zones from five boreholes. Acoustic televiewer logging and borehole geophysical loggings produced images, orientations and geophysical properties of fractures which intersect with boreholes. According to the result of the investigations, subsurface fractures can be grouped as three preferred orientations(B1, B2 and B3), which correspond to S1, S2 and S4/S5 of surface fracture sets, respectively. Actually, B1 set is expected to be intensely developed at subsurface. However, it has low frequency of intersection with boreholes due to its parallel or sub-parallel direction to boreholes. According to the inference of conductive fractures, B1 and B3 sets have possibilities of water flow and their intersection lines are also thought to consist of important conduits of groundwater flow. In particular, faults which are parallel to foliations control major groundwater flow in the study area.

• Applied Chemistry for Engineering
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• v.30 no.4
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• pp.421-428
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• 2019

This paper describes a methode to extract yellow pigment from curcuma and turmeric containing natural color curcumin whose target color indexes of L, a, and b were 87.0 7.43, and 88.2, respectively. The pH range and extraction temperature used for the reaction surface analysis method were from pH 3 to pH 7 and between 40 and $70^{\circ}C$, respectively for both natural products. A central synthesis planning model combined with the method was used to obtain optimal extraction conditions to produce the color close to target. Results and regression equations show that the color space and difference of curcuma and turmeric have the greatest influence on the value. In the case of curcuma, the optimum conditions to satisfy all of the response theoretical values of color coordinates of L (74.67), a (5.69), and b (70.08) were at the pH and temperature of 3.43 and $54.8^{\circ}C$, respectively. The experimentally obtained L, a, and b, values under optimal conditions were 72.92, 5.32, and 72.17, respectively. For the case of turmeric, theoretical numerical color coordinates of L, a, and b, under the pH of 5.22 and temperature of $50.4^{\circ}C$ were 82.02, 7.43, and 72.86 respectively. Whereas, the experiment results were L (81.85), a (5.39), and b (71.58). Both cases showed an error range within 1%. Therefore, it is possible to obtain a low error rate when applying the central synthesis planning model to the reaction surface analysis method as an optimization process of the dye extraction of natural raw materials.

• BMB Reports
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• v.45 no.3
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• pp.141-146
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• 2012

Protein tyrosine phosphatase 1B (PTP1B) is important in the regulation of metabolic diseases and has emerged as a promising signaling target. Previously, we reported the PTP1B inhibitory activity of Rheum undulatum (RU). In the present study, we investigated the metabolic regulatory effects of RU in a high-fat diet (HFD) model. RU treatment significantly blocked body weight gain, which was accompanied by a reduction of feed efficiency. In addition, it led to a reduction of liver weight mediated by overexpression of PPAR${\alpha}$ and CPT1 in the liver, and an increase in the expression of adiponectin, aP2, and UCP3 in adipose tissue responsible for the reduction of total and LDL-cholesterol levels. Chrysophanol and physcion from RU significantly inhibited PTP1B activity and strongly enhanced insulin sensitivity. Altogether, our findings strongly suggest that 2 compounds are novel PTP1B inhibitors and might be considered as anti-obesity agents that are effective for suppressing body weight gain and improving lipid homeostasis.

• Proceedings of the KSR Conference
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• 2010.06a
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• pp.110-115
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• 2010

Recently the deeply underground tunnels have been increased along the subway railroads of urban area compared to the past subway railroads. The Shin-Gum-Ho subway station (the Fifth lines, the depth : 46m) which is the third among the deep subway stations in the Korea was chosen as the model of deeply underground stations, and attempted to do simulation of fire. This station consists of three entrance, the basement first floor (B1), the basement second floor (B2), the basement eighth floor or platform (B8) and escalators and stairs from B2 to B8. The total number of grid was about 9,000,000 to make simulation of fire and smoke from the platform to entrance in this research, and the grid system was divided into 19 blocks to increase the efficiency of this simulation. The FDS (Fire Dynamics Simulation) was chosen to make the simulation of fire, and the model of turbulent flow was LES (Large Eddy Simulation). Each block is processed in a CPU using parallel processing of MPI (Message Passing Interface). The resource of CPU for this simulation is a ten of Intel 3.0 GHz Dual CPU (20 CPU).

• Journal of the Korean Society of Industry Convergence
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• v.7 no.3
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• pp.281-288
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• 2004

The objective of this study is to propose a methodology of the flood runoff analysis in steep mountainous basins and the analysis basin is the Jasa valley basin in Chungju city Analyzing the spatial pattern of the rainfall in 1994. 6 30~7.1, the seasonal rainy front was tied up in the whole central district, and the rainfall center was moving from the northern Chungbuk province to the northern Kyongbuk province and caused heavy storm. Analyzing the temporal pattern with the Huff method, the 52.5% of the rainfall was concentrated on the 3rd quartile. Rainfall frequency analysis is accomplished by five distribution types; 2-parameter Lognomal, 3-parameter Lognomal, Pearson Type III, Log-Pearson Type III and Extremal Type I distribution Rainfall-runoff analysis in Jasa valley basin was made using HEC-HMS model. Jasa valley basin was divided into 3 sub-basins and the analysis point was 3 points{A, B and C point) With the rainfall data measured by the 10 minutes, the flood runoff also was calculated by as many minutes. SCS CN model, Clark UH model and Muskingum routing model in HEC-HMS model were used to simulate the runoff volume using selected rainfall event.

• Journal of the Society of Naval Architects of Korea
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• v.35 no.4
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• pp.98-108
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• 1998

Hull design data is currently prepared by a 2D CAD system and re-input to 3D CAD systems specialized for detail design or to a structural analysis system. In this paper, sharing design data among different CAD systems has been studied. Based on STEP methodology, a neutral model is generated from 2D AutoCAD drawings. To handle a geometric data of this model, the non-manifold model of ACIS is used because it can support various CAD data representation such as 2D graphic entities, 3D wireframe, 3D surface model, and solid B-Rep/CSG model. It is observed that a mon-manifold model can easily be transformed to a 3-D wireframe model for the hull detail design system AutoDef or a FE model for the structural analysis system Nastran.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.8
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• pp.1046-1055
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• 2000

The flow and thermal phenomena in flat tubes of radiator are analyzed numerically. To predict the characteristics of heat transfer and pressure drop, the flow analysis program for three-dimensional complex geometry is developed, which adopted an non-staggered grid system and Cartesian velocities as dependent variables of the momentum equations. Using the developed program, the effect of tube specifications on the heat transfer characteristics is investigated for various flat tubes. From this study, the following results are obtained; (1) For the same hydraulic diameter($D_h{\doteq}5.2$mm), the Nusselt numbers of three basic modeis(D, J, and H-model) are 8.71, 8.92, and 10.58, respectively, and the pressure drops of D-, J-, and H-model are predicted as $-3.08{\times}10^{-2}\;Pa,\;-3.12{\times}10^{-2}\;Pa,\;and\; -3.98{\times}10^{-2}$ Pa, (2) In case of the same flat tube specification, the fins must be brazed at upper tube surface because the heat is more vividly transferred. Therefore, it is found that the H- model is the most effective tube as a heat exchanger and these results are used as a fundamental data for the design of tube.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.339-339
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• 1994

It has been reported that Indole-3-carbinol (I3C), a naturally occurring compound In cruclferous vegetables, exerts anticarcinogenic activity In several organs In rodents. The modifying effects of I3C were therefore assessed uging a rat multi-organ carcinogenesis model. A total of 100 male Sprague-Dawley rats were divided Into 3 groups. Animals of groups 1 and 2 were sequentially treated with diethylnitrosamine (DEN; 100 mg/kg b.w., i.p.), N-methylnitrosourea (NNU; 20 mg/kg b.w., 4 times for 2 weeks, i.p), and dihydroxy-di-N-propylnitrosauine (DHPN; 0.1% In d.w. for 2 weeks) for 4 weeks (DMD treatment). Animals of groups 1 and 3 were given the diet of 0.25% I3C for 20 weeks after DMD initiation and then were given basal diet for 28 weeks. All animals were sacrificed at week 24 and 52, respectively. I3C has been clearly demonstrated promoting effects on the development of glutathione S-transferase placental form (GST-P) positive hepatic foci at 24 weeks of the experiment. And I3C also exerted promoting potential In the hepatocellular adenoma (4/14; 29%) and the adenoma (7/14; 50%) of the thyroid gland at 52 weeks of the experiment. Therefore, I3C may promote hepatocarcinogenesis and thyroid tumorigenesis in the rat multi-organ carcinogenesis model.

• Transactions of Materials Processing
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• v.23 no.3
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• pp.145-150
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• 2014

Precision control of the slab is crucial for product quality and production economy in hot strip mills. The current study presents a new model for predicting width spread of a slab with a rectangular cross section during roughing. The model is developed on the basis of the extremum principle for a rigid plastic material and a three dimensional admissible velocity field. This model incorporates the effect of process variables such as the shape factor and the ratio of width to thickness. We compare the results of this model to 3-D finite element (FE) process simulations and also to results from a previous study.

• Food Science of Animal Resources
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• v.33 no.2
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• pp.155-161
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• 2013

This study developed predictive models to evaluate the kinetic behaviors of Bacillus cereus and Staphylococcus aureus in milk during storage at various temperatures. B. cereus and S. aureus (3 Log CFU/mL) were inoculated into milk and stored at $10^{\circ}C$, $15^{\circ}C$, $20^{\circ}C$, and $30^{\circ}C$, as well as $5^{\circ}C$, $15^{\circ}C$, $25^{\circ}C$, and $35^{\circ}C$, respectively, while bacterial populations were enumerated. The growth data were fitted to the modified Gompertz model to estimate kinetic parameters, including the maximum specific growth rate (${\mu}_{max}$; Log CFU/[$mL{\cdot}h$]), lag phase duration (LPD; h), lower asymptote ($N_0$; Log CFU/mL), and upper asymptote ($N_{max}$; Log CFU/mL). To describe the kinetic behavior of B. cereus and S. aureus, the parameters were fitted to the square root model as a function of storage temperature. Finally, the developed models were validated with the observed data, and Bias (B) and Accuracy (A) factors were calculated. Cell counts of both bacteria increased with storage time. Primary modeling yielded the following parameters; ${\mu}_{max}$: 0.14-0.75 and 0.06-0.51 Log CFU/mL/h; LPD: 1.78-14.03 and 0.00-1.44 h, $N_0$: 3.10-3.37 and 2.09-3.07 Log CFU/mL, and $N_{max}$: 7.59-8.87 and 8.60-9.32 Log CFU/mL for B. cereus and S. aureus, respectively. Secondary modeling yielded a determination of coefficient ($R^2$) of 0.926.0.996. B factors were 1.20 and 0.94, and A factors were 1.16 and 1.08 for B. cereus and S. aureus, respectively. Thus, the mathematical models developed here should be useful in describing the kinetic behaviors of B. cereus and S. aureus in milk during storage.