• Journal of Korea Multimedia Society
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• v.10 no.12
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• pp.1566-1576
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• 2007

Camera pose information from 2D face image is very important for making virtual 3D face model synchronize with the real face. It is also very important for any other uses such as: human computer interface, 3D object estimation, automatic camera control etc. In this paper, we have presented a camera position determination algorithm from a single 2D face image using the relationship between mouth position information and face region boundary information. Our algorithm first corrects the color bias by a lighting compensation algorithm, then we nonlinearly transformed the image into $YC_bC_r$ color space and use the visible chrominance feature of face in this color space to detect human face region. And then for face candidate, use the nearly reversed relationship information between $C_b\;and\;C_r$ cluster of face feature to detect mouth position. And then we use the geometrical relationship between mouth position information and face region boundary information to determine rotation angles in both x-axis and y-axis of camera position and use the relationship between face region size information and Camera-Face distance information to determine the camera-face distance. Experimental results demonstrate the validity of our algorithm and the correct determination rate is accredited for applying it into practice.

• Journal of KIISE
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• v.41 no.11
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• pp.992-1005
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• 2014

Coreference resolution finds all expressions that refer to the same entity in a document. Coreference resolution is important for information extraction, document classification, document summary, and question answering system. In this paper, we adapt Stanford's Multi-pass sieve system, the one of the best model of rule based coreference resolution to Korean. In this paper, all noun phrases are considered to mentions. Also, unlike Stanford's Multi-pass sieve system, the dependency parse tree is used for mention extraction, a Korean acronym list is built 'dynamically'. In addition, we propose a method that calculates weights by applying transitive properties of centers of the centering theory when refer Korean pronoun. The experiments show that our system obtains MUC 59.0%, $B_3$ 59.5%, Ceafe 63.5%, and CoNLL(Mean) 60.7%.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.7
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• pp.926-935
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• 2015

The efficiency of genome-wide association analysis (GWAS) depends on power of detection for quantitative trait loci (QTL) and precision for QTL mapping. In this study, three different strategies for GWAS were applied to detect QTL for carcass quality traits in the Korean cattle, Hanwoo; a linkage disequilibrium single locus regression method (LDRM), a combined linkage and linkage disequilibrium analysis (LDLA) and a $BayesC{\pi}$ approach. The phenotypes of 486 steers were collected for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area, and marbling score (Marb). Also the genotype data for the steers and their sires were scored with the Illumina bovine 50K single nucleotide polymorphism (SNP) chips. For the two former GWAS methods, threshold values were set at false discovery rate <0.01 on a chromosome-wide level, while a cut-off threshold value was set in the latter model, such that the top five windows, each of which comprised 10 adjacent SNPs, were chosen with significant variation for the phenotype. Four major additive QTL from these three methods had high concordance found in 64.1 to 64.9Mb for Bos taurus autosome (BTA) 7 for WWT, 24.3 to 25.4Mb for BTA14 for CWT, 0.5 to 1.5Mb for BTA6 for BFT and 26.3 to 33.4Mb for BTA29 for BFT. Several candidate genes (i.e. glutamate receptor, ionotropic, ampa 1 [GRIA1], family with sequence similarity 110, member B [FAM110B], and thymocyte selection-associated high mobility group box [TOX]) may be identified close to these QTL. Our result suggests that the use of different linkage disequilibrium mapping approaches can provide more reliable chromosome regions to further pinpoint DNA makers or causative genes in these regions.

• The Korean Journal of Pain
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• v.28 no.4
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• pp.244-253
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• 2015

Background: Although circumcision for phimosis in children is a minor surgical procedure, it is followed by pain and carries the risk of increased postoperative anxiety. This study examined predictive factors of postoperative pain and anxiety in children undergoing circumcision. Methods: We conducted a prospective cohort study of children scheduled for elective circumcision. Circumcision was performed applying one of the following surgical techniques: sutureless prepuceplasty (SP), preputial plasty technique (PP), and conventional circumcision (CC). Demographics and base-line clinical characteristics were collected, and assessment of the level of preoperative anxiety was performed. Subsequently, a statistical model was designed in order to examine predictive factors of postoperative pain and postoperative anxiety. Assessment of postoperative pain was performed using the Faces Pain Scale (FPS). The Post Hospitalization Behavior Questionnaire study was used to assess negative behavioral manifestations. Results: A total of 301 children with a mean age of $7.56{\pm}2.61$ years were included in the study. Predictive factors of postoperative pain measured with the FPS included a) the type of surgical technique, b) the absence of siblings, and c) the presence of postoperative complications. Predictive factors of postoperative anxiety included a) the type of surgical technique, b) the level of education of mothers, c) the presence of preoperative anxiety, and d) a history of previous surgery. Conclusions: Although our study was not without its limitations, it expands current knowledge by adding new predictive factors of postoperative pain and postoperative anxiety. Clearly, further randomized controlled studies are needed to confirm its results.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.191-200
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• 2014

We investigated the anxiolytic-like activity of ${\alpha}$-asarone (AAS) from Acorus gramineus in an experimental rat model of anxiety induced by repeated administration of the exogenous stress hormone corticosterone (CORT). The putative anxiolytic effect of AAS was studied in behavioral tests of anxiety, such as the elevated plus maze (EPM) test and the hole-board test (HBT) in rats. For 21 consecutive days, male rats received 50, 100, or 200 mg/kg AAS (i.p.) 30 min prior to a daily injection of CORT. Dysregulation of the HPA axis in response to the repeated CORT injections was confirmed by measuring serum levels of CORT and the expression of corticotrophin-releasing factor (CRF) in the hypothalamus. Daily AAS (200 mg/kg) administration increased open-arm exploration significantly in the EPM test, and it increased the duration of head dipping activity in the HBT. It also blocked the increase in tyrosine hydroxylase (TH) expression in the locus coeruleus (LC) and decreased mRNA expression of brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, in the hippocampus. These results indicated that the administration of AAS prior to high-dose exogenous CORT significantly improved anxiety-like behaviors, which are associated with modification of the central noradrenergic system and with BDNF function in rats. The current finding may improve understanding of the neurobiological mechanisms responsible for changes in emotions induced by repeated administration of high doses of CORT or by elevated levels of hormones associated with chronic stress. Thus, AAS did exhibit an anxiolytic-like effects in animal models of anxiety.

• Journal of Astronomy and Space Sciences
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• v.23 no.3
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• pp.177-188
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• 2006

A total of 920 observations (230 in ${\Delta}B$, 230 in ${\Delta}V$, 230 in ${\Delta}R$, 230 in ${\Delta}I$) for V523 Cas were made on 5 nights from January 6 to 24 in 2003 using the 61cm telescope with 2K CCD camera of the Sobaeksan Optical Astronomy Observatory of KASI. From our observations 9 times of minimum light were newly determined. Combined analysis of our new BVRI light curves with the double-lined radial velocity curves of the Rucinski et al.'s (2003) were made with the 2004 Wilson-Devinney (WD) binary model to yield new physical parameters of the V523 system. Small asymmetries in light curves were explained with the adoption of a cool spot on the hot primary and a hot spot on the cool secondary.

• Journal of Korea Multimedia Society
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• v.9 no.4
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• pp.434-442
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• 2006

This paper proposes a color-matching 3D look-up table that simplifies the complex color-matching procedure between a monitor and a mobile display device, where the image colors are processed in a device-independent color space, such as CIEXYZ or CIELAB, and gamut mapping performed to compensate the gamut difference. The transform from a device-dependent RGB color space to a device-independent color space is implemented by performing display characterization. The mobile LCD characterization error using the S-curve model is larger than the tolerance error since the mobile LCD has the channel-chromaticity-inconstancy and channel-dependence characteristics. In this paper we reduced the characterization error using the electro-optical transfer functions of X, Y, and Z value for R, G, B, C, M, Y, K components. Experimental results demonstrated that 64 ($4{\times}4{\times}4$) was the smallest size of color-matching look-up table that could produce an image with an acceptable reproduction error, based on a comparison of color-matched images resulting from the proposed color-matching look-up table and complex step-by-step color-matching procedures.

• Journal of Korean Neurosurgical Society
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• v.37 no.4
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• pp.287-292
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• 2005

Objective: Recent clinical studies have demonstrated that intracisternal administration of recombinant tissue plasminogen activator(rt-PA) can facilitate the normal clearing of blood from the subarachnoid space. Urokinase, a first generation fibrinolytic agent, has been used to liquify such clots with some success. Therefore, recombinant tissue plasminogen activator, a second generation fibrinolytic drug that may be safer and more effective, is studied to evaluate its dosage to lyse clots in vitro and reactivity in the brain parenchyme. Methods: Intracerebral hematomas were created by stereotactically injecting 2ml of clotted autogenous blood into the brain parenchyme of total 28 anesthetized adult cats (weighting 3.8 to 4.1 kg). The control animals (group A) received 1 ml of normal saline injected into the clots and the experimental animals received each 0.1 mg of rt-PA (group B), 0.5mg of rt-PA (group C) and 1 mg of rt-PA (group D) at 6 hours after the clot injection. Results: 1. The amount of remained clots after lysing the hematomas were as follows: $1.80{\pm}0.17ml$ in group A, $1.65{\pm}0.23ml$ in group B, $0.61{\pm}0.37ml$ in group C and $0.52{\pm}0.34$ in group D. The result indicated that hematomas in rt-PA treated groups (C & D) were lysed better than the control group. 2. At least 0.5mg of rt-PA should be required for the lysis of 2ml of hematomas. 3. Light microscopic examination revealed no histological evidence of hemorrhage in tissue sections from each brain. Conclusion: Recombinant tissue plasminogen activator may be safely and effectively employed for the lysis of intracerebral hematomas in animal model.

• The Journal of the Acoustical Society of Korea
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• v.39 no.2
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• pp.87-97
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• 2020

In this paper, the design of piezoelectric Micro-machined Ultrasonic Transducer (pMUT) for wideband ultrasonic radiation in air was investigated. One of the methods to achieve wide frequency bandwidth in single device is modeling the transducer to multi-resonance system. The new pMUT was designed as a multi-resonance system with the addition of a suitable acoustic structure to the front and back of a thin film structure. A new pMUT consisting of thin film parts, radiation parts, and packaging parts is designed with a Lumped Parameter Model (L.P.M). Finally, it was validated as a Finite Element Method (FEM) simulation. The final designed pMUT achieved a frequency band of 102 kHz ~ 132 kHz (-3 dB).

• IMMUNE NETWORK
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• v.13 no.3
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• pp.86-93
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• 2013

In the present study, we investigated if priming of autoreactive $CD8^+T$ cells would be inhibited by competitive peptides for major histocompatibility complex (MHC) class I binding. We used a mouse model of vitiligo which is induced by immunization of $K^b$-binding tyrosinase-related protein 2 (TRP2)-180 peptide. Competitive peptides for $K^b$ binding inhibited IFN-${\gamma}$production and proliferation of TRP2-180-specific $CD8^+T$ cells upon ex vivo peptide restimulation, while other MHC class I-binding peptides did not. In mice, the capability of inhibition was influenced by T-cell immunogenicity of the competitive peptides. The competitive peptide with a high T-cell immunogenicity efficiently inhibited priming of TRP2-180-specific $CD8^+T$ cells in vivo, whereas the competitive peptide with a low T-cell immunogenicity did not. Taken together, the inhibition of priming of autoreactive $CD8^+T$ cells depends on not only competition of peptides for MHC class I binding but also competitive peptide-specific $CD8^+T$ cells, suggesting that clonal expansion of autoreactive T cells would be affected by expansion of competitive peptide-specific T cells. This result provides new insights into the development of competitive peptides-based therapy for the treatment of autoimmune diseases.