• Title/Summary/Keyword: model B3

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Experimental Studies on the Hair Growth Activity of Fractions and Extract of Arisaematis Rhizoma in C57B/6N Mice (C57BL/6N 생쥐에서 천남성 추출물과 분획물의 발모효과에 대한 실험적 연구)

  • Kwon, Kyung-Suk;Lee, Moon-Won;Jeong, Il-Kook;Jeong, Han-So;Song, Beom-Yong;Song, Jeong-Mo;Lee, Chang-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.3
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    • pp.619-630
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    • 2009
  • To investigate the hair growth activity of fractions and extract of Arisaematis Rhizoma in the hair removed skin of normal and spontaneous alopecia areata model in C57B/6N mice. These experiments were performed with the macroscopic, microscopic, immunohistochemical(VEGF, c-kit, PKC-${\alpha}$, TGF and FGF) and RT-PCR(TGF-${\beta}$, IGF, prolactin and placenta lactogen) methods. The results were as follows: Macroscopic observation after topical application of vehicle, 50% EtOH as control and extract of Arisaematis Rhizoma to the hair removed skin of C57BL/6N mice on the 9th, 11th and 15th day. Extensive hair growth activity was observed in treated group with extract of Arisaematis Rhizoma on the 9th, 11th and 15th day. In Arisaematis Rhizoma extracts treated group, hair follicles of middle stage of anagen was observed and it were grown down to subcutaneous tissue of skin in all the normal mice on 15th day. But in control group, most of hair follicles of telogen phase was observed in skin. The treatment of extract of Arisaematis Rhizoma increased expression of IGF(145%) and placenta lactogen(108%) in the skin of normal C57BL/6N mice on the 11th day compared to control group(100%). But expression of TGF-${\beta}$(90%) and prolactin(91%) decreased in the skin of normal C57B/6N mice on the 11th day compared to control group(100%). After application of fractions(chloroform, ethyl acetate and water fractions) of Arisaematis Rhizoma extract for 9th day, hair growth effect was observed in whole skin area in 50% of normal mice. But in control group, hair growth effect was not observed in whole skin area of normal mice. Immunoreactive density of VEGF, c-kit, PKC-${\alpha$ and FGF in skin of fractions of Arisaematis Rhizoma extracts was strongly stained in epidermis, bulge, secondary hair germ cells, cutaneous trunci m., subcutaneous tissue, root sheath compare to control group on the 9th day. In spontaneous alopecia areata model, The hair growth activity of Arisaematis Rhizoma extrat treated group(75%) was observed to be strong compared to control group(O%) on 7th day. These experiments suggest that fractions and extracts of Arisaematis Rhizoma may stimulate the topical hair growth activity. Thus it can be useful for treatment of alopecia areata.

A Study on the Design and Fabrication of GHz Magnetic Thin Film Inductor Utilizing Co90Fe10/SiO2 Multilayer (Co90Fe10/SiO2 Multilayer를 이용한 GHz 자성박막 인덕터 설계 및 제작에 관한 연구)

  • 공기준;윤의중;진현준;박노경;문대철
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.5B
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    • pp.985-991
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    • 2000
  • In this paper, the optimum structure of 2GHz magnetic thin film planar inductor were designed and fabricated to reduce the inductor area and to maximize the inductance L and quality factor Q of the inductor. The optimum design was performed utilizing Co90Fe10 layer multilayered with SiO2 layers to avoid the eddy-current skin effect and considering new lumped element model. New magnetic thin film inductors operating at 2GHz were fabricated on a Si substrate utilizing photo-lithography and lift-off techniques. The frequency characteristics of L, Q, and impedance in more than fifty identical inductors were measured using an RF Impedance Analyzer(HP4291B with HP16193A test fixture). The self-resonant frequencies(SRF) of the inductors were measured by a Vector Network Analyzer(HP8510). The developed inductors have SRF of 1.8 to 2.3GHz, L of 47 to 68nH, and Q of 70 to 80 near 1GHz. Finally, high frequency, high performance, planar micro-inductor(area=30.8 x 30.8il$^2$) with maximized L and Q were fabricated succefully.

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Series-Type Hybrid Electric Bus Fuel Economy Increase with Optimal Component Sizing and Real-Time Control Strategy (최적용량매칭 및 실시간 제어전략에 의한 직렬형 하이브리드 버스의 연비향상)

  • Kim, Minjae;Jung, Daebong;Kang, Hyungmook;Min, Kyoungdoug
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.3
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    • pp.307-312
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    • 2013
  • The interest in reducing the emissions and increasing the fuel economy of ICE vehicles has prompted research on hybrid vehicles, which come in the series, parallel, and power-split types. This study focuses on the series-type hybrid electric vehicle, which has a simple structure. Because each component of a series hybrid vehicle is larger than the corresponding component of the parallel type, the sizing of the vehicle is very important. This is because the performance may be greater or less than what is required. Thus, in this research, the optimal fuel economy was determined and simulated in a real-world system. The optimal sizing was achieved based on the motor, engine/generator, and battery for 13 cycles, where DP was used. The model was developed using ASCET or a Simulink-Amisim Co-simulation platform on the rapid controller prototype, ES-1000.

Steady-State Performance Analysis of Air Conditioner with Multi-Indoor Units (복수 실내기를 가지는 에어컨의 정상상태 성능해석)

  • Hur, Hyun;Lee, Jin Wook;Jung, Eui Guk;Kim, Byung Soon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.11
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    • pp.705-715
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    • 2016
  • In this study, the cycle performance of an air conditioner with multi-indoor units is analyzed and simulated. The cycle performance could be predicted through the integration of mathematical formulation for these devices. The condenser pressure is obtained by an iteration process to match the mass flow rates of the compressor and the expansion valve and the evaporator pressure is determined by an iteration process, in which the suction super heat is tracing the targeted super heat. The required software was developed by system programming. the software algorithm is extended to predict the cycle performance of an air conditioner system with multi-indoor units, and then the numerical results are compared with experimental results. This mathematical model is validated from the result of experiments conducted on 8.3kW air conditioner. The errors in capacity, electronic power, and COP are found to be within 10% in general.

Enhanced Wireless Network Security in Military Environments (군사 환경에서의 향상된 무선 네트워크 보안)

  • Kim, Jin Woo;Shin, Soo Young
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.11
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    • pp.1341-1348
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    • 2016
  • In this paper, we propose method to enhance security performance using HT-STBC with artificial noise under Wier-Tap channel model that exist with legitimate receiver and illegal eavesdropper. Conventional STBC with artificial noise scheme has a weakness that a limited increase in the BER of the difference between the receiver and an eavesdropper, when used over QPSK modulation. To solve this problem, we suggest HT-STBC combining hadamard transform and STBC with artificial noise for reduce BER of receiver than the conventional scheme and demonstrated through simulation that also increased BER difference between the receiver and an eavesdropper. By the simulation results, when used proposed scheme, showed approximately 3dB improvement in performance compared to the conventional scheme.

Effect of n-Butanol on the Mixed Micellar Properties of Sodium Dodecylsulfate(SDS) with Sodium Dodecylbenzenesulfonate(DBS) (Sodium Dodecylsulfate(SDS)와 Sodium Dodecylbenzenesulfonate(DBS)의 혼합미셀화에 미치는 n-Butanol의 효과)

  • 이병환
    • Journal of the Korean Chemical Society
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    • v.41 no.1
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    • pp.12-17
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    • 1997
  • The critical micelle concentrations(CMC*) and the counterion binding constants(B) in a micellar state of the mixed surfactant systems of sodium dodecylsulfate(SDS) with sodium dodecylbenzenesulfonate(DBS) at 25℃ in pure water and in aqueous solutions of n-butanol were determined as a function of α1 (the overall mole fraction of SDS) by the use of electric conductivity method. Various thermodynamic parameters(Xi, γi, Ci, aiM, β, ΔHmix and ΔGm0 for the micellization of SDS/DBS mixtures were calculated and analyzed by means of the equations derived from the nonideal mixed micelle model. The effect of n-butanol on the mixed micellization of SDS/DBS mixtures have been measured and analyzed by comparing the values of the thermodynamic parameters in pure water with those in aqueous solutions of n-butanol(0.1 M, 0.2 M, and 0.3 M).

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Synthetic Conditions and Rheological Characteristics of Barium Sulfate (황산바륨의 합성조건과 유동학적 특성)

  • Shin, Wha-Woo;Kim, Jun-Hea;Choi, Kwang-Sik;Chang, Young-Soo;Lee, Kwang-Pyo
    • YAKHAK HOEJI
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    • v.36 no.6
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    • pp.538-547
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    • 1992
  • Optimal synthetic condition of barium sulfate were investigated from the viewpoint of yield and bulkiness according to a randomized complete block design proposed by G.E.P. Box and K.B. Wilson. Barium chloride and magnesium sulfate were utilized as reactants in order to prepare barium sulfate in this study. It was found that optimum temperature range of reactant solutions was $60{\sim}100^{\circ}C$ and the optimum concentration range of the reactant solutions was $10{\sim}17.3%$ and $10{\sim}20%$ respectively, on the viewpoint of yield and bulkiness. The optimum mole ratio of $BaCI_2$ to $BaSO_4$ was in the range of $1.50{\sim}2.0$ and the optimum mole ratio of $BaCI_2$ to $BaSO_4$ was in the range of $1.50{\sim}2.0$ and the optimum reacting time range was $15{\sim}20$ minutes. The optimum drying temperature range was $110{\sim}130^{\circ}C$ from the viewpoint of yield, but it was $90{\sim}110^{\circ}C$ on the basis of bulkiness. Apparent viscosity of barium sulfate suspensions dispersed in various concentrations of Na. CMC was measured by using Brookfield synchrolectric viscometer model LVT, the relative equation, log ${\eta}_{sp}=A+B.{\phi}$ was examined and the equation was found to agree fairly well. 1 w/v% Na. CMC aqueous solution and 0.1 volume fraction of $BaSO_4$ powder were optimum in the preparation of $BaSO_4$ suspension showing highest viscosity at infinite shearing.

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The GRS80 Gravimetric Geoid from GEM9 Potential Coefficients and Terrestrial Gravity Anomalies in the South Korea Region (GEM9 위성자료와 지상자료의 조합에 의한 남한지역의 GRS80 중력지오이드)

  • Cho, Kyu Jon;Lee, Young Jin;Cho, Bong Whan
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.13 no.1
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    • pp.141-149
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    • 1993
  • The gravimetric geoid of the South Korea Region was computed on Geodetic Reference System 1980(GRS80) using a combination of satellite-derived potential coefficients and terrestrial gravaty data. $10^{\prime}{\times}10^{\prime}$ mean gravity anomalies were obtained from surface gravity data for the outer zones, $1^{\circ}{\times}1^{\circ}$ equal area mean anomalies were used for the inner zones, and point gravity anomalies were used for the innermost zones in the Stokes integration. The GRS80 potential coefficients were obtained from modification of GEM9 data and Integration was extended over a spherical cap of $30^{\circ}$ from the integration area. The results of a free-air geoid show that the systematic mean difference of approximately 2~3m in comparison of OSU89B model.

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Modeling of Flame Acceleration Considering Complex Confinement Effects in Combustible Gas Mixture (가연성 기체 혼합물에서 복잡한 구조에 따른 화염 가속 모델링)

  • Gwak, Min-Cheol;Yoh, Jai-Ick
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.3
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    • pp.315-324
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    • 2012
  • This paper presents a numerical investigation of the deflagration-to-detonation transition (DDT) of flame acceleration by a shock wave filled with an ethylene/air mixture as the combustible gas, considering geometrical changes by using obstacles and bent tubes. The model used consists of the reactive compressible Navier-Stokes equations and the ghost fluid method (GFM) for complex boundary treatment. Simulations with a variety of bent tubes with obstacles show the generation of hot spots through flame and strong shock-wave interactions, and restrained or accelerated flame propagation due to geometrical effects. In addition, the simulation results show that the DDT occurs with a nearly constant chemical heat-release rate of 20 MJ/($g{\bullet}s$) in our numerical setup. Furthermore, the DDT triggering time can be delayed by the absence of unreacted material together with insufficient pressures and temperatures induced by different flame shapes, although hot spots are formed in the same positions.

Performance Assessment of Turbulence Models for the Prediction of Moderator Thermal Flow Inside CANDU Calandria (칼란드리아 내부의 감속재 열유동 해석을 위한 난류모델 성능 평가)

  • Lee, Gong-Hee;Bang, Young-Seok;Woo, Sweng-Woong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.3
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    • pp.363-369
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    • 2012
  • The moderator thermal flow in the CANDU calandria is generally complex and highly turbulent because of the interaction of the buoyancy force with the inlet jet inertia. In this study, the prediction performance of turbulence models for the accurate analysis of the moderator thermal flow are assessed by comparing the results calculated with various types of turbulence models in the commercial flow solver FLUENT with experimental data for the test vessel at Sheridan Park Engineering Laboratory (SPEL).Through this comparative study of turbulence models, it is concluded that turbulence models that include the source term to consider the effects of buoyancy on the turbulent flow should be used for the reliable prediction of the moderator thermal flow inside the CANDU calandria.