• Title/Summary/Keyword: mixing efficiency

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Particle Size Control of Poly(Lactide-co-Glycolide) Microspheres for Oral Antigen Delivery Systems (경구용 항원 수송체 모델로서 폴리락티드-글리콜리드 마이크로스피어의 입자도 조절)

  • Song, Il-Yong;Song, Seo-Hyun;Song, Woo-Heon;Cho, Seong-Wan;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.29 no.4
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    • pp.315-321
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    • 1999
  • Poly (lactide-co-glycolide) (PLGA) microspheres containing ovalbumin (OVA) as a model protein drug were prepared by double emulsification method, and various conditions such as mixing rate, volume of outer phase and isopropyl alcohol concentration in outer phase during secondary emulsification were observed to control the size of microspheres. In addition, entrapment efficiency of OVA and protein denaturation were also evaluated. As the rate of stirring was increased, the size of particles was decreased. But excessive stirring increased the particle size of microspheres. In a preparation condition of small volume of outer phase, the particle size was decreased but the entrapment efficiency was increased. Adding isopropyl alcohol to outer phase decreased the size of particles, but increased the entrapment efficiency. Microparticles should have smaller size than $10\;{\mu}m$ to be uptaked by Peyer's patch in small intestine. High speed of mixing and relatively small volume of outer phase are needed to reduce the size. In addition, appropriate amount of isopropyl alcohol in outer phase also plays an important role in size reduction of PLGA microspheres.

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A Study on the 0-Dimensional Simulation of He+Ne+Xe Gas and the Discharge Characteristics in Plasma Display Panel (플라즈마 디스플레이 패널용 He+Ne+Xe 혼합가스에서 소량 Xe 함유에 대한 영 차원 수치해석과 방전특성연구)

  • Jeong, Hae-Yeong;Choe, Hun-Yeong;Kim, Geun-Su;Kim, Seong-Ik;Song, Bong-Sik;Park, Heon-Geon;Lee, Seok-Hyeon
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.9
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    • pp.436-442
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    • 2002
  • Recently color AC PDP(plasma display panel) technology is rapidly improved. However, the luminous efficiency improvement is a key issue for making plasma display into a large-area flat display. In this paper, we suggest a new concentration of Xe in He-Ne-Xe gas mixture in order to achieve a high luminous efficiency of color AC PDPs. We calculated the densities of 25 species as a function of the time zero dimensional simulation using CVODE solver and we compared the results of zero dimensional simulation with a measurement of photo wave brightness and luminous efficiency, in order to find the optimum mixing condition of He-Ne-Xe gas in color plasma display panel. We obtained a high discharge speed under Xe mixing ratio of 1% by simulation and confirmed that through measuring photo wave.

Accuracy and applicable range of a reconstruction technique for hybrid rockets

  • Nagata, Harunori;Nakayama, Hisahiro;Watanabe, Mikio;Wakita, Masashi;Totani, Tsuyoshi
    • Advances in aircraft and spacecraft science
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    • v.1 no.3
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    • pp.273-289
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    • 2014
  • Accuracy of a reconstruction technique assuming a constant characteristic exhaust velocity ($c^*$) efficiency for reducing hybrid rocket firing test data was examined experimentally. To avoid the difficulty arising from a number of complex chemical equilibrium calculations, a simple approximate expression of theoretical $c^*$ as a function of the oxidizer to fuel ratio (${\xi}$) and the chamber pressure was developed. A series of static firing tests with the same test conditions except burning duration revealed that the error in the calculated fuel consumption decreases with increasing firing duration, showing that the error mainly comes from the ignition and shutdown transients. The present reconstruction technique obtains ${\xi}$ by solving an equation between theoretical and experimental $c^*$ values. A difficulty arises when multiple solutions of ${\xi}$ exists. In the PMMA-LOX combination, a ${\xi}$ range of 0.6 to 1.0 corresponds to this case. The definition of $c^*$ efficiency necessary to be used in this reconstruction technique is different from a $c^*$ efficiency obtained by a general method. Because the $c^*$ efficiency obtained by average chamber pressure and ${\xi}$ includes the $c^*$ loss due to the ${\xi}$ shift, it can be below unity even when the combustion gas keeps complete mixing and chemical equilibrium during the entire period of a firing. Therefore, the $c^*$ efficiency obtained in the present reconstruction technique is superior to the $c^*$ efficiency obtained by the general method to evaluate the degree of completion of the mixing and chemical reaction in the combustion chamber.

Thermal environment evaluation of KBS open hall with mixing ventilation and downward displacement ventilation systems (혼합환기와 하향 압출환기시스템이 동반된 KBS공개홀의 온열환경 평가)

  • 권용일;권순석
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.10 no.2
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    • pp.147-154
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    • 1998
  • This study was carried out for evaluating the interior thermal environment in KBS Open hall with large ceiling height and large space. Ventilation systems of KBS Open hall have combined mixing ventilation and downward displacement ventilation system. Temperature and velocity was measured 130 locations with low level(0.1m), mid level(0.6m) and high level(1.1m). But relative humidity was measured at 15 locations. The subjective thermal sensation was made an inquiry of occupancy at the location measured physical elements.

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A Study on the One-way Optical Image Transmission Through Optical Fiber by Degenerate Four Wave Mixing (축퇴 4 광파 혼합에 의한 광섬유에서의 광영상 직접전송에 관한 연구)

  • 안병구;이우상;김은수;양인응
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.25 no.4
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    • pp.460-466
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    • 1988
  • In this paper, the theory and experiments on the one-way optical image transmission through optical fiber by using degenerate four wave mixing in BSO single crystal are demonstrated. From the theoretical analysis, the diffraction efficiency of phase conjugate wave in BSO single crystal is greatly dependent on applied electric field intensity, diffraction grating period formed in the crystal and incident beam ratio, those are also in good agreement with the experimental results. Based on the experimental results, we have arranged the typical degenerate four wave mixing system in the optimal conditions (applied electric field, E. = 5kV/cm` diffraction grating period, 3\ulcorner` beam ratio of backward pump wave versus signal wave, 2.7) and realized one-way optical image transmission system through optical fiber using BSO single crystal.

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Electro-Optical Characteristics of External Electrode Fluorescent Lamp depending on Gas pressure and mixing ratio

  • Kim, Hyung-Dong;Jeon, Hyun-Woo;Lee, Chang-Ho;Yoon, Jung-Hyun;Kim, Jae-Bum;Lim, Jong-Ho;Shin, Jong-Keun;Chung, In-Jae
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.792-794
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    • 2008
  • We investigated influence of gas pressure and mixing ratio on the electro-optical properties of External Electrode Fluorescent Lamp (EEFL). The experimental results indicated that luminance and efficiency became the maximum at lower gas pressure and Ar mixing ratio.

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Removal Characteristics of Cyclic Ethers in Biological Wastewater Treatment System (고리형 에테르의 생물학적 처리 특성)

  • Lee, Sung-Ryul;Jeong, Yeon-Koo
    • Journal of Environmental Science International
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    • v.17 no.3
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    • pp.343-350
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    • 2008
  • The fate of two cyclic ethers, THF(Tetrahydrofuran) and 1,4-Dioxane, in conventional biological wastewater treatment plants was investigated using sequential activated sludge process. Removal efficiency of THF were about 86% in average, which was greater than that of 1,4-Dioxane, 30%. However, it was not clear whether the removal of cyclic ethers in biological system was caused by microbial activity or not. Thus treatability tests were conducted by batch experiments. The effects of mixing, aeration and the addition of activated sludge on the removal of cyclic ethers were investigated in batch experiments. THF was totally removed by mixing and aeration in 24 hours while removal ratio of 1,4-Dioxane was at most 30% for the same period. This results could be ascribed to the differences in Henry's law constants between the two chemicals. In addition, biological degradation including biosorption was not obviously observed in these batch tests.

An Experimental Investigation on Flow Field in a Pipe with Sinusoidally Wavy Surface by PIV (PIV를 이용한 3차원 파형관 내부 유동장의 실험적 연구)

  • 김성균
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.16 no.4
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    • pp.368-373
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    • 2004
  • A flow field in a passage with periodically converging-diverging cross-section is investigated experimentally by PIV measurement. A tube with a sinusoidally wavy cross section is one of several devices employed for enhancing the heat and mass transfer efficiency due to turbulence promotion and unsteady vortical motion. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and transient flow regime by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. At Re=2000, evidences of the global mixing are captured at 2.5 wavy module through the variation of RMS values and instantaneous velocity plot.

A Study on CFD Simulation of Rotational Flow in Stirred Tanks (교반 탱크 내 회전 유동의 CFD 해석 연구)

  • Cho, Chan-Young;Nam, Jin-Hyun;Shin, Dong-Hoon;Chung, Tae-Yong
    • Proceedings of the SAREK Conference
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    • 2009.06a
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    • pp.1406-1411
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    • 2009
  • Stirred tanks are widely used in various industries for mixing operations and chemical reactions for single- or multi-phase fluid systems. In this study, a numerical study was conducted to predict the mixing characteristics in a simple stirred tank. The flow in the model stirred tank was calculated utilizing the multiple reference frame (MRF) and the sliding mesh (SM) capabilities of a commercial CFD code (Fluent 6.2). The results of the flow simulation were analyzed in terms of the mixing efficiency, and the applicability of MRF and SM methods was also discussed.

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Characterization of Mixing in Reaction Modules for the Production of Chemical Materials (화학소재 생산용 반응 모듈의 혼합 성능 해석)

  • Seo J.H.;Kim Y.S.;Choe J.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2006.05a
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    • pp.537-538
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    • 2006
  • Split and recombine type reaction module was made by electrical discharge machining. The reaction module has special features to well mix the two reactants which have high flow ratio or high concentrations difference. It could be achieved by deviding one flow equally by two and inserting second flow in between. The mixing performance was measured by a parallel competing reaction with iodide-iodate system. The result shows that the developed three inlets micromixer has better mixing efficiency than comercialized Y type micromixer.

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