• Mass Spectrometry Letters
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• 제8권3호
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• pp.59-64
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• 2017

In clinical diagnosis, it's well known that the abnormal level of uric acid (UA) in human body is implicated in diverse human diseases, for instance, chronic heart failure, gouty arthritis, diabetes, and so on. As a primary method, an isotope dilution mass spectrometry (IDMS) has been used to obtain the accurate quantity of UA in blood or serum and also develop the certificated reference material (CRM) so as to provide a SI-traceability to clinical laboratories. Due to the low solubility of UA in water, an ammonium hydroxide ($NH_4OH$) has been considered as a promising solvent to increase the solubility of UA that enables the preparation of both UA and its isotope standard solution for next IDMS-based absolute quantification. But, because of using this $NH_4OH$ solvent, it gives rise to the unwanted degradation of UA. In this study, we sought to optimize condition for the stability of UA in $NH_4OH$ solution by varying the mole ratios of UA to $NH_4OH$, followed by ID-LC-MRM analysis. In addition, we also inspected minutely the effect of the storage temperatures. Additionally, we also performed the quantitative analysis of UA in the KRISS serum certificated reference material (CRM, 111-01-02A) with diverse mixing ratios of UA to $NH_4OH$ and then compared those values to its certification value. Based on our experiments, adjusting the mole ratio of 1/2 ($UA/NH_4OH$) with the storage temperature of $-20^{\circ}C$ is an effective way to secure both the solubility and stability of UA in $NH_4OH$ solution for next IDMS-based quantification of UA in serum.

• 한국구조물진단유지관리공학회 논문집
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• 제15권3호
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• pp.178-185
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• 2011

본 연구는 강모래와 부순 모래를 일반적인 혼합방법과 아스팔트 골재 혼합에 사용되는 Driscoll 방법으로 각각 혼합하여 그 특성을 알아보고, Driscoll 방법의 콘크리트용 골재에 대한 적용성을 판단하고자 하였다. 이에 따라 일반혼합과 Driscoll 방법으로 혼합한 골재의 조립율 및 입도곡선, 굳지 않은 콘크리트의 특성 중 슬럼프와 공기량 및 굳은 콘크리트의 특성 중 28일 압축강도 시험을 통해 혼합방법의 따른 특성을 알아보고자 하였다. 아스팔트 골재의 혼합에 사용되는 Driscoll 방법을 사용하여 콘크리트 골재를 혼합하였을 때 일반적인 혼합방법과 비교하여 슬럼프, 공기량, 28일 압축강도가 오차수준 정도의 미미한의 차이를 나타내었다. 따라서 아스팔트 골재 혼합에 사용되는 Driscoll 방법은 콘크리트용 잔골재의 혼합에도 적용 가능할 것으로 판단된다.

• 자원환경지질
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• 제18권3호
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• pp.247-251
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• 1985

The sulfide and carbonate mineral samples for sulfur and carbon isotope studies were collected from Sangdong, Geodo, Yeonhwa, Shinyemi and Janggun mines which are distributed in the Metallogenetic Province of the Taebaeg Mt. Region. The ${\delta}S^{34}$ values of molybdenite, pyrite, arsenopyrite, pyrrhotite, chalcopyrite, sphalerite and galena from the above mines are similar and within the range of +1.66 to +6.77‰ with the exception of chalcopyrite from Geodo mine ranging from -1.58 to 1.96‰, while the sulfide minerals are dominated by positive values between +3.05 and +5.08‰. It is suggested that the major sulfur source is genetically related to the Cretaceous granitic activity. The average ${\delta}C^{13}$ values of calcite from limestone, calcite from calcite vein in ore bodies and granite, and rhodochrosite from ore bodies are -0.60‰, -2.69‰ and -6.00‰, respectively. The data on carbon isotope compositions indicate that the calcite from limestone originated in marine environment, the rhodochrosite in hydrothermal solution, and calcite from calcite vein and granite in the mixing condition of marine and hydrothermal waters. The temperatures of mineralization by the sulfur isotopic composition coexisting pyrite-pyrrhotite from Yeonhwa No.1, sphalerite-galena from Weolam and Dong-jeom of Yeonhwa No.1 mine, sphalerite-galena and pyrite-galena from Janggun mine were $273^{\circ}C$, $460{\sim}511^{\circ}C$, $561{\sim}690^{\circ}C$, $341^{\circ}C$ and $375^{\circ}C$, respectively.

• 한국식품영양학회지
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• 제27권3호
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• pp.435-446
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• 2014

This study was conducted to develop an optimal composite recipe of nutritional cookies containing Chinese artichoke (Stachy sieboldii Miq) powder. Rice powder was partially substituted with Chinese artichoke (Stachy sieboldii Miq) powder to reduce its content. The optimal sensory composite recipe was determined by 3 concentrations of Chinese artichoke (Stachy sieboldii Miq) powder, butter, and sugar, using the central composite design. In addition, the mixing condition of Chinese artichoke (Stachy sieboldii Miq) powder rice cookies was optimized by subjecting the cookies to a sensory evaluation and instrumental analysis using the response surface methodology (RSM). The effects of the addition of the three variables on the quality of Chinese artichoke (Stachy sieboldii Miq) rice powder cookies were assessed in terms of color, hardness, sweetness and sensory evaluation. The results of the sensory evaluation produced values very significant for flavor, texture, sweetness, appearance, and overall quality (p<0.05). The results of instrumental analysis showed significant values in moisture content, spreadability, sweetness (p<0.01), lightness, redness, and hardness (p<0.001). As a results, the optimal sensory ratio of Chinese artichoke (Stachy sieboldii Miq) rice cookies was determined to be Chinese artichoke (Stachy sieboldii Miq) powder 4.22 g, butter 120.00 g, and sugar 130.00 g.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2001년도 학술대회지
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• pp.222-227
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• 2001

고층 건축물에 사용할 CFT 기둥에 적합한 고유동 콘크리트를 개발하고, 이를 적용하여 실물대의 Mockup 실험을 진행하여 시공시 문제점 및 관리기술을 확보하고자 하였다. 사전에 재료선정실험을 진행하여 CFT 기둥에 가장 적합한 재료를 선정하고, 시공성을 향상시키기 위하여 2단계에 걸쳐 실험을 진행하였다. 1차 실험에서는 타설방법, 유도관의 유무, 타선속도, 낙하높이 등을 변수로 실험을 진행하여 그중 시공성이 우수하면서 품질관리에 문제가 없는 변수를 대상으로 2차 실험을 진행하였다 2차 실험에서는 $9.6{\cal}m$ 높이의 강관에 타설방법을 달리하여 콘크리트 충전실험을 진행하였다. 실험결과 시공성 향상을 위하여 기존의 시공지침과 차이를 가진 변수에서도 우수한 충전성능을 보임을 확인하였다.

• 대한치과기공학회지
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• 제35권2호
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• pp.127-136
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• 2013

Purpose: In order to find out the impact of changes in polymerization conditions of orthodontic acrylic resin on maximum load. Methods: While maintaining mixing ratio 3:1 of polymer and monomer in spray-on way in the production condition of polymerization temperature $25^{\circ}C$ or $37^{\circ}C$ for 10 minutes or 30 minutes of polymerization time by pressure $3kfg/cm^2$ or $6kfg/cm^2$ in the lab maintaining $25^{\circ}C$ of room temperature, the change in maximum load rise rate was tested by producing 5 acrylic resin specimens for orthodontics per group to meet the standards of $25mm{\times}2mm{\times}2mm$ and using INSTRON with the 3rd bar 2mm in diameter and parallel support bending device of $15{\pm}0.1mm$ as test equipment showing 30.00mm/min of crosshead speed, $50{\pm}16$ N/min of load ratio in the laboratory of $24^{\circ}C$ room temperature and as a result, the following results were obtained. Results: 1. When increasing pressure from $3kfg/cm^2$ to $6kfg/cm^2$, maximum load was lowered by -4.285%. 2. When increasing polymerization time from 10 minutes to 30 minutes, maximum load rose by 3.848%. 3. When increasing polymerization temperature from $27^{\circ}C$ to $37^{\circ}C$, maximum load rose by 5.854%. Conclusion: Considering the above test results that polymerization time and polymerization temperature when polymerizing acrylic resin for orthodontics according to changes in working conditions had an impact on the rate of rise of maximum load values but the rate of rise was lowered when increasing pressure from $3kfg/cm^2$ to $6kfg/cm^2$, we came to a conclusion that high pressure more than necessary does not affect the rate of rise of maximum load.

• 한국추진공학회지
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• 제22권3호
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• pp.53-64
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• 2018

본 논문에서는 초음속 유동장 내 연료 수직 분사 조건에서 분사구의 형상에 따른 연료/공기 혼합 특성을 분석하고자 하였다. 이를 위해 동일한 분사구 출구 면적과 유량 조건에 대해 수소와 공기에 대한 비반응 유동장 전산 해석을 수행하였다. 해석 결과의 검증을 위하여 자유류 마하수 3.38, 제트-자유류 운동량 플럭스비 1.4 인 평판 분사 시험을 모의하였다. 5개의 서로 다른 형상을 갖는 분사구를 이용하여 형태에 따른 박리 구간, 분사 제트의 구조의 차이를 살펴보고 분사구 후류에서 수소의 침투 높이와 수소-공기의 혼합에 따른 가연 면적에 변화를 확인함으로써 분사구 형상에 따른 연료/공기 혼합 특성을 정량적으로 비교하였다.

• Bulletin of the Korean Chemical Society
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• 제29권5호
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• pp.974-978
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• 2008

Removal of heavy metal ions ($Cd^{2+}$ and $Zn^{2+}$) by electrocoagulation (ECG) was investigated in an acidic condition, which is necessary for re-using or discharging the mediated electrochemical oxidation (MEO) media. Effects of various parameters such as electrolytes, current densities, and electrode materials were examined for a metal-contaminated MEO system using $Fe^{2+}/Fe^{3+}$ pairs as a mediator. It was found that ECG with Al electrodes is greatly affected by the presence of $Fe^{2+}$. [$Cd^{2+}$] and [$Zn^{2+}$] remain constant until [$Fe^{2+}$] reaches a certain concentration level (ca. 10 mM). This preferential removal of $Fe^{2+}$ during ECG with Al electrodes is not alleviated by controlling current densities, potential programs, and solution mixing. ECG with Fe electrodes, on the other hand, resulted in relatively fast removal of $Cd^{2+}$ and $Zn^{2+}$ under coexistence of $Fe^{2+}$, indicative of the different role between $Fe^{n+}$ generated from an electrode and $Fe^{2+}$ initially present in a solution. When ECG was performed with Fe electrodes until [$Fe^{n+}$] became the same as the concentration of initially present $Fe^{2+}$, [$Cd^{2+}$] and [$Zn^{2+}$] were reduced to one-tenth of the initial concentrations, suggesting the possibility of a continuous use of the medium for a subsequent MEO process.

• 대한영양사협회학술지
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• 제19권1호
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• pp.1-13
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• 2013

The purpose of this study was to determine the optimal mixing condition of tomato powder and sugar for producing chiffon cake. The experiment was designed according to the central composite design of response surface, which yielded ten experimental points, including two replicates. Physiochemical and sensory properties were measured, and theses values applied to mechanical models. A canonical form and perturbation plot showed the influence of each ingredient on the final product mixture. The results of the physiochemical analysis of each sample showed significant differences in sweetness (P<0.01), color L (P<0.001), color a (P<0.001), color b (P<0.05), hardness (P<0.05), and cohesiveness (P<0.01). The sensory measurements were significantly different in color (P<0.05), appearance (P<0.05), flavor (P<0.05), sweetness (P<0.01), moistness (P<0.05), and overall acceptability (P<0.05). The optimal formulation, calculated using the numerical and graphical method, was determined to be 59.27 g tomato powder and 285.66 g sugar. The sensory evaluation showed significantly higher preferences in the color, flavor, appearance, texture, sweetness, tenderness, moistness and overall quality of the optimized chiffon cake compared to the controlled chiffon cake. The optimized chiffon cake also showed a high antioxidative activity compared to the controlled chiffon cake. Our results show that chiffon cake prepared with tomato powder enhances sensory characteristics and antioxidative activity.

• 한국재료학회지
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• 제24권8호
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• pp.407-412
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• 2014

Currently, diopside ($MgCaSi_2O_6$) crystal glaze is used frequently for pottery works or in earthen wares, though the process is not straightforward. However, to create and control the positions and sizes of the crystals in desired amounts when making pottery is difficult. To solve this problem, a diopside crystal seed was created at a temperature of $1450^{\circ}C$. After planting this seed in the glaze, a glaze combination and firing process which allows a user to create crystals with the desired position and at the desired size were established. In addition, in order to investigate the creation process of the crystals, the growth patterns of the crystals were observed and examined using Raman spectrography and XRD and SEM analyses. As a result, the optimum synthesis condition of the diopside seed was created by mixing 1 mole of $CaCo_3$, 0.2 mole of $(MgCo_3)_4(MgCoH)_2{\cdot}5H_2O$ and 2 moles of $SiO_2$ and then applying a firing process to the mixture at $1,450^{\circ}C$ for 30 minutes. The optimum glaze content of the seed was 70 % feldspar, 20 % limestone and 10 % $MgCo_3$. For the firing process, it was confirmed that the size of crystal is larger with a longer firing time at $1100^{\circ}C$ by completing a two-hour process at $1280^{\circ}C$. In addition, the diopside crystal has columnar structure and is less than $1{\mu}m$ in size.