• Title/Summary/Keyword: mitigate

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Effects of Omahwan(OMH) on CD4+, CD8+ T cell and Immune Organ Index in Rat (오마환(烏麻丸)이 백서(白鼠)의 혈액내(血液內) CD4+, CD8+ T cell 및 면역기관(免疫器官) 장기지수(臟器指數)에 미치는 영향(影響))

  • Lee Song-Shil;Lee Sang-Jae;Kim Kwang-Ho
    • Journal of Society of Preventive Korean Medicine
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    • v.5 no.1
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    • pp.76-89
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    • 2001
  • OMH which is known for its properties of recruiting vitality, is composed of Polygonum multiflorum Thunb. and Sesamum indicum DC.. This formula is known to possess the properties of recruiting vitality, blackening white hair and expanding life span. 16-week-old SD-Rats were treated with OMH for 16 days. After 24 hours, the rats were treated with MTX(Mthotrexate is oral administrated for 4 days(1mg/kg/day), in order to lower immunity. Then, These rats were classified in to groups, the N-16 group(not specially tested), the Control group(MTX), the OMH-L group(2.5% OMH+MTX)&the OMH-H group(10% OMH+MTX) and 6 rats were assigned to each group. After 18 hours from MTX treatment the organ index of the rats from each group Thymus and Spleen were measured. The percentage of CD+4, CD8+ T cell were measured and compared by flow cytometer. 1) Rats from the OHM-L&OMH-H group showed higher organ indexes of the Thymus and Spleen compared to the rats from the Control Group. This proves that OMH possesses the properties to mitigate degenerations of immunity($F_{thymus}=20.162,\;F_{spleen}=5.882$, ANDVA, p<0.05). 2) The rats from the two OMH groups showed higher rates of CD4+ T cell counts compared to the control group(F=26.906, ANOVA, p<0.05). CD8+ T cell showed lower rates compared to the Control group, but showed no differences within the two OMH groups(F=1.254, ANOYA, p>0.05). CD4+/CD8+ showed higher rates in the two OMH groups compared to the control group which can be thought as a proof that OMH prevents depression of immune response(F=10.554, ANOVA, p<0.05). In this test 16 week-old rats were used, which can be considered as the middle and prime age of the human being. These rats were treated with OMH which ended up showing properties of mitigating degeneration of immune responses and maintaining T-cell rates within the blood. It was possible to study that OMH possesses the properties to increase immune responses.

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Pulling Force and Manure Spreading Characteristic of Tractor-drawn Animal Slurry Manure Sub-soil Injector (가축분뇨액비 지중살포기의 견인력 및 살포 특성)

  • Choe K. J;Lee S. H.;Ryu B. K.;Oh K. Y.;Park H. J.;Lee S. T.
    • Journal of Animal Environmental Science
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    • v.11 no.1
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    • pp.25-34
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    • 2005
  • The study aimed to develop a tractor drawn animal slurry manure sub-soil injector for arable land and thus, can reduce the waste management cost through effective treatment and utilization of animal slurry manure. The application of animal slurry manure to agricultural land will probably be one of the most effective ways to enrich the soil with vital nutrients. However, some existing slurry manure spenders are not suitable in the field because of their adverse effects to the environment. Based on this premise, a prototype was designed and assembled using 5 sub-soiling standards attached to the sin injector device. The traction force of the Prototype measured in the depth of 10 cm and 15 cm from the ground surface of a paddy field was 1,062 kgf and 1,214 kgf, respectively. A unique feature of the machine was that there was an equal volume of slurry manure flowing from each delivery pipe and regulated by a pressurized container that was likewise synchronized with the speed of the tractor The sub-soiling manure injection system can mitigate or reduce the harmful emission of obnoxious gases and malodor during the injection operation.

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A Study on the Perceptions of University Researchers on Data Management and Sharing (데이터 관리와 공유에 대한 대학 연구자들의 인식에 관한 연구)

  • Kim, Jihyun
    • Journal of the Korean Society for Library and Information Science
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    • v.49 no.3
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    • pp.413-436
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    • 2015
  • This study aimed to investigate data management practices of university researchers in Korea, as well as their experiences and perceptions of data sharing and reuse. For this purpose, it performed semi-structured interviews of 13 researchers who agreed to participate in interviews followed by a survey conducted prior to this study. The interview participants created or collected research data with various types and formats, and only a few conducted data documentation while they recognized its significance. The majority of participants perceived the period that data would be useful as the period that data can be employed for publications. However, most participants wanted to preserve data beyond the period that data would be considered useful and it indicates they have no small need for data storage and preservation. Participants usually shared data with those whom they have known, such as a personal research group or a research team. While some completely agree with the principle that publicly-funded data should be open to the public, others partially agreed or disagreed with it. Most participants were concerned about being scooped, plagiarism, and maintaining the first right to publish and incentives to mitigate the concerns would be necessary.

Pedestrian Dead Reckoning based Position Estimation Scheme considering Pedestrian's Various Movement Type under Combat Environments (전장환경 하에서 보행자의 다양한 이동유형을 고려한 관성항법 기반의 위치인식 기법)

  • Park, SangHoon;Chae, Jongmok;Lee, Jang-Myung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.10
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    • pp.609-617
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    • 2016
  • In general, Personal Navigation Systems (PNSs) can be defined systems to acquire pedestrian positional information. GPS is an example of PNS. However, GPS can only be used where the GPS signal can be received. Pedestrian Dead Reckoning (PDR) can estimate the positional information of pedestrians using Inertial Measurement Unit (IMU). Therefore, PDR can be used for GPS-disabled areas. This paper proposes a PDR scheme considering various movement types over GPS-disabled areas as combat environments. We propose a movement distance estimation scheme and movement direction estimation scheme as pedestrian's various movement types such as walking, running and crawling using IMU. Also, we propose a fusion algorithm between GPS and PDR to mitigate the lack of accuracy of positional information at the entrance to the building. The proposed algorithm has been tested in a real test bed. In the experimental results, the proposed algorithms exhibited an average position error distance of 5.64m and position error rate in goal point of 3.41% as a pedestrian traveled 0.6km.

Analysis of Risk Classification on the Urban Flood Damage in Changwon city (창원시 용도지역별 침수 피해에 따른 위험등급화 분석)

  • Park, Ki-Yong;Jeong, Jin-Ho;Jeon, Won-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.685-693
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    • 2017
  • This study aims to effectively respond to urban local rainstorms by classifying the risk against flood damage for each use district. The risk classification is based on sensitivity analysis of the socio-economic damage caused by local rainstorms in Changwon city, Korea by a Fuzzy model using data, such as the districts that provide institutional bases for land use, land prices, which estimate the property values, and floor area ratios, which measures the density and areas of flood damage. The analysis result indicated that flood damage in five districts of Changwon (Masan happo-gu, Masan Hoewon-gu, Sungsan-gu, Euichang-gu, and Jinhae-gu) is highest in the order of commercial areas, residential areas, industrial areas, and forests, which was attributed to high land price and floor area ratio of commercial areas. On the other hand, specific analysis in Masan Hoewon-gu and Sungsan-gu was different from the previous result, indicating that the risk against flood damage may vary according to the districts depending on their local conditions. The analysis from this study can be applied to future urban planning and be used as a guideline to estimate the potential flood damage. Overall, this study is meaningful in that it proposes an effective management of land use as a new resolution to mitigate of urban flood damage within a broader perspective of climate change and urbanization.

Bone-Preserving Decompression Procedures Have a Minor Effect on the Flexibility of the Lumbar Spine

  • Costa, Francesco;Ottardi, Claudia;Volkheimer, David;Ortolina, Alessandro;Bassani, Tito;Wilke, Hans-Joachim;Galbusera, Fabio
    • Journal of Korean Neurosurgical Society
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    • v.61 no.6
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    • pp.680-688
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    • 2018
  • Objective : To mitigate the risk of iatrogenic instability, new posterior decompression techniques able to preserve musculoskeletal structures have been introduced but never extensively investigated from a biomechanical point of view. This study was aimed to investigate the impact on spinal flexibility caused by a unilateral laminotomy for bilateral decompression, in comparison to the intact condition and a laminectomy with preservation of a bony bridge at the vertebral arch. Secondary aims were to investigate the biomechanical effects of two-level decompression and the quantification of the restoration of stability after posterior fixation. Methods : A universal spine tester was used to measure the flexibility of six L2-L5 human spine specimens in intact conditions and after decompression and fixation surgeries. An incremental damage protocol was applied : 1) unilateral laminotomy for bilateral decompression at L3-L4; 2) on three specimens, the unilateral laminotomy was extended to L4-L5; 3) laminectomy with preservation of a bony bridge at the vertebral arch (at L3-L4 in the first three specimens and at L4-L5 in the rest); and 4) pedicle screw fixation at the involved levels. Results : Unilateral laminotomy for bilateral decompression had a minor influence on the lumbar flexibility. In flexion-extension, the median range of motion increased by 8%. The bone-preserving laminectomy did not cause major changes in spinal flexibility. Two-level decompression approximately induced a twofold destabilization compared to the single-level treatment, with greater effect on the lower level. Posterior fixation reduced the flexibility to values lower than in the intact conditions in all cases. Conclusion : In vitro testing of human lumbar specimens revealed that unilateral laminotomy for bilateral decompression and bone-preserving laminectomy induced a minor destabilization at the operated level. In absence of other pathological factors (e.g., clinical instability, spondylolisthesis), both techniques appear to be safe from a biomechanical point of view.

Donation Expenses and Corporate Value: A Focus on the Corporate Governance Structure (기부금 지출과 기업 가치: 기업지배구조를 중심으로)

  • Kim, Soo-Jung;Kang, Shin-Ae
    • Journal of Distribution Science
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    • v.12 no.8
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    • pp.113-121
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    • 2014
  • Purpose - Recently, the number of corporations that practice environmental and social responsibility, besides engaging in traditional profit-seeking activities, has been growing steadily, as interest in Corporate Social Responsibility (CSR) is increasing. Recent research on CSR practices has identified the relationship between CSR activities and corporate value as one of the main issues in this respect. Considering that donations constitute a large proportion of a company's charitable activities, we considered the extent of donation expenses as a charitable activity in order to mitigate sample selection bias. Specifically, we analyzed the impact of donation expenses on firm value, while investigating if this impact varied in response to the level of corporate governance of firms. Research design, data, and methodology - We used non-financial firms listed on the Korean Stock Exchange, having their fiscal year end in December, and the sample period was 2006-2013. For the dependent variable, Tobin's q was used as the corporate value, and for the independent variable, donations were measured as the donation-expense-to-sales ratio. Corporate governance scores, as rated by the Korea Corporate Governance Service, were used to measure corporate governance levels because they consider the overall aspects of governance, including ownership structure, the board of directors, and the audit mechanism of individual companies. To examine the impact of donations on a company in relation to the level of corporate governance, we estimated regression models using the interaction terms of the governance dummy and donation variables. Then, we further estimated the regression models of two sub-samples that were classified according to the level of corporate governance. Similar to previous studies, the study uses variables that affect firm value, such as R&D expenditure, advertising expenses, EBITDA, debt-to-equity ratio, sales growth, company age, and company size as control variables. Results - The empirical results show that firm value significantly increased in response to an increase in donation expenses. Upon including the interaction terms of governance level dummy variables and donations, the coefficients of the interaction terms show significant positive values, while those of donation variables show significant negative values. In the strong governance sub-sample, the relationship between the donation expenses and corporate value was statistically positive (+) and significant. However, in the weak governance sub-sample, the relationship between the donation expenses and corporate value was statistically insignificant and negative (-). Conclusions - The empirical results suggest that donation expenses are significantly linked to an enhanced corporate value if firms have a good corporate governance structure. However, if the corporate governance structure is weak, the same relationship is not necessarily observed. The results of this study show that if a firm has high corporate governance, CSR practices enhance the company's reputation such that it has a positive (+) relationship with corporate value. If a firm has weak corporate governance, on the other hand, CSR practices are recognized as an agency cost and do not increase corporate value.

Incident Detection for Urban Arterial Road by Adopting Car Navigation Data (차량 궤적 데이터를 활용한 도심부 간선도로의 돌발상황 검지)

  • Kim, Tae-Uk;Bae, Sang-Hoon;Jung, Heejin
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.13 no.4
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    • pp.1-11
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    • 2014
  • Traffic congestion cost is more likely to occur in the inner city than interregional road, and it accounts for about 63.39% of the whole. Therefore, it is important to mitigate traffic congestion of the inner city. Traffic congestion in the urban could be divided into Recurrent congestion and Non-recurrent congestion. Quick and accurate detection of Non-recurrent congestion is also important in order to relieve traffic congestion. The existing studies about incident detection have been variously conducted, however it was limited to Uninterrupted Traffic Flow Facilities such as freeway. Moreover study of incident detection on the interrupted Traffic Flow Facilities is still inadequate due to complex geometric structure such as traffic signals and intersections. Therefore, in this study, incident detection model was constructed using by Artificial Neural Network to aim at urban arterial road that is interrupted traffic flow facility. In the result of the reliability assessment, the detection rate were 46.15% and false alarm rate were 25.00%. These results have a meaning as a result of the initial study aimed at interrupted traffic flow. Furthermore, it demonstrates the possibility that Non-recurrent congestion can be detected by using car navigation data such as car navigator system device.

SINR Maximizing Collaborative Beamforming with Enhanced Robustness Against Antenna Correlation (안테나 간 상관도에 강건한 SINR 최대화 협력적 빔포밍 기법)

  • Kim, Jae-Won;Sung, Won-Jin
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.46 no.4
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    • pp.95-103
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    • 2009
  • In this paper, a generation method of transmit and receive beamforming vectors based on base station cooperation is proposed which maximizes the user SINR in mobile cellular multi-user MIMO systems. There are two main sources of interference which deteriorate the performance of the system, i.e. the inter-user interference caused by the usage of the same radio resource for multiple users in the system, and the inter-cluster interference from neighboring base stations which are not participating in cooperative transmission. The proposed scheme cancels out the inter-user interference by using the block diagonalization(BD) method, and mitigate the inter-cluster interference by using optimal transmit and receive beamforming vectors based on optimal combining(OC) with the statistic information of inter-cluster interference. We perform computer simulations to verify the performance of the proposed scheme, and compare the result to the conventional performance obtained from utilizing the receiver side information only or utilizing the information from neither sides. The performance evaluations are conducted not only over the independent MIMO channels, but over correlated MIMO channels to demonstrate the robustness of the proposed scheme over the channels with correlation among antennas.

NRZ versus RZ Modulation Format in Lumped Dispersion Managed Systems (집중형 분산 제어 시스템에서 NRZ 변조 형식 대 RZ 변조 형식)

  • Lee, Seong-Real;Cho, Sung-Eon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.2
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    • pp.328-335
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    • 2008
  • The system performance of NRZ format in WDM transmission system with lumped dispersion management(DM) and optical phase conjugator(OPC) is compared with that of RZ format. It is confirmed that eye opening penalty(EOP) of both NRZ and RZ format in WDM transmission system having lumped DM combined with OPC are greatly improved than those in WDM system with only OPC. The optimal net residual dispersion(NRD) in the case of RZ format is decided to so small value that path-averaged dispersion coefficient become almost zero, while that in the case of NRZ format is decided to larger value, for the best improvement of overall WDM channels. It is also confirmed that EOP in the case of RZ format is more improved than that in the case of NRZ format in lumped DM with optimal NRD. This is resulted from that lumped DM combined with OPC suppress the signal distortion due to intrachannel four-wave mixing(IFWM) and intrachannel cross phase modulation(IXPM). Consequently, lumped DM combined with OPC proposed in this paper is effective technique to mitigate intrachannel nonlinearities in WDM transmitting RZ format.