• 한국응용곤충학회지
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• 제16권1호
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• pp.41-45
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• 1977

침투성살충제 Curaterr(Carbofuran), Cytrolane(Mephosfolan), Disyston(Disulfoton) 립제의 대두 파종용 처리효과를 검토하여 다음과 같은 결과를 얻었다. 1. 공시약제 모두 대두의 입묘에 영향을 주었는데 Carbofuran 4.6mg, 9.2mg(유효성분량) 처리를 제외하고는 Carbofuran 13.8mg 처리를 포함한 Mephosfolan, Disulfoton 처리에서 비교적 낮은 입묘유를 보였다. 2. Carbofuran과 Mephosfolan은 초기의 콩잎에 약해가 비교적 심하였으나 Disulfoton은 약해가 거의 나타나지 않았다. Carbofuran과 Mephosfolan 처리에서는 자엽과 제일본엽에 갈색내지 흑갈색 반점 또는 엽록을 따라 갈색엽소징색이 나타났으며 Disulfoton은 엽선에 약간의 위축징상이 보였다. 그리고 약량의 증가에 따라 약해가 증대하였다. 3. 공시약제 모두 어느 약량에서나 약 3개월에 걸쳐 콩진딧물의 방제효과가 좋았으며 약량이 높아짐에 따라 방제효과가 더욱 좋은 경향을 보였다. 4. 약제처리구에서 두점박이응애의 밀도가 낮어 방제효과를 인정할 수 있었다. 특히 Mephosfolan과 Disulfoton은 처리약량의 증가에 따라 방제효과가 증대하였으며 Disulfoton의 용당 13.8mg(a.i) 처리는 약제처리 82일까지 계속 응애의 밀도가 가장 낮었다. 5. 콩나바아에 의한 콩의 초해율은 처리, 무처리 또는 약량간에 차이가 없었으며 수량에 있어서도 그들 사이에 차이가 없었다. 6. 이상의 결과로 보아 공시약제의 대두 파종용 일회처리로서는 콩진딧물과 두점박이응애의 방제는 가능하나 콩나방의 방제는 어려운 것으로 나타났다.

• Journal of Microbiology and Biotechnology
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• 제17권8호
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• pp.1394-1398
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• 2007

Acaricidal activity of the active constituent derived from Pyrus ussuriensis fruits against Dermatophagoides farinae and D. pteronyssinus was examined and compared with that of the commercial benzyl benzoate. The $LD_{50}$ value of the ethyl acetate fraction obtained from the aqueous extract of P. ussuriensis fruits was 9.51 and $8.59{\mu}g/cm^3$ against D. farinae and D. pteronyssinus, respectively. The active constituent was identified as quinone by spectroscopic analyses. On the basis of $LD_{50}$ values with quinone and its congeners, the compound most toxic against D. farinae was quinone ($1.19{\mu}g/cm^3$), followed by quinaldine (1.46), benzyl benzoate (9.32), 4-quinolinol (86.55), quinine (89.16), and 2-quinolinol (91.13). Against D. pteronyssinus, these were quinone ($1.02{\mu}g/cm^3$), followed by quinaldine (1.29), benzyl benzoate (8.54), 4-quinolinol (78.63), quinine (82.33), and 2-quinolinol (86.24). These results indicate that the acaricidal activity of the aqueous extracts can be mostly attributed to quinone. Quinone was about 7.8 and 8.4 times more toxic than benzyl benzoate against D. farinae and D. pteronyssinus. Additionally, quinaldine was about 6.4 and 6.6 times more toxic than benzyl benzoate against D. farinae and D. pteronyssinus, respectively. Furthermore, the skin color of the dust mites was changed from colorless-transparent to dark brown-black by the treatment of quinone. These results indicate that quinone can be very useful as potential control agents, lead compounds, or the indicator of house dust mites.

• 한국응용곤충학회지
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• 제43권3호
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• pp.257-262
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• 2004

병해충 방제약제로 등록된 51종의 농약(살충제 25종, 살비제 11종, 살균제 11종 그리고 농약보조제 4종)에 대한 으뜸애꽃노린재 약충과 성충의 독성을 조사하였다. 살충제 중에서는 flpronil, lufenuron, acetamiprid+fipronil, $\alpha$-cypermethrin+flufenoxuron, buprofezin+amitraz of 독성이 낮았고, 살비제 중에서는 acequinocyl, bifenazate, chlorfenapyr, etoxazole, fenpyroximate, flufenoxuron, milbemectin, spirodiclofen, tebufenpyrad가 독성이 낮거나 없었다. 살균제와 농약보조제는 모두 낮은 독성을 보였다. 이상의 결과로 보아 시설 병해충의 종합관리체계 에서 으뜸애꽃노린재에 독성이 적은 약제와 으뜸애꽃노린재를 함께 이용할 수 있을 것이다.

• 한국응용곤충학회지
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• 제34권1호
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• pp.40-45
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• 1995

전국 8개 지역별 각 사과원에서 채집된 점박이응애(Tetranychus urticae Koch)에 대한 저항성 정도를 일본 감수성 계통과 비교한 결과 지역별 현저한 감수성 차이를 보였다. Azocyclotin, fenpropathrin, propargite 및 abamectin에 대해서는 낮거나 중간 정도의 저항성을, dicofol, fenpyroximate 및 pyridaben에 대해서는 높은 저항성을 나타내었다. 이들 계통은 한종 또는 두종 이상의 약제에 대해 감수성을 보여 특정 지역에 대해서는 적당한 살비제의 선택적 이용으로 점박이응애를 효과적으로 방제할 수 있을 것으로 사료된다.

• 대한본초학회지
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• 제30권1호
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• pp.95-101
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• 2015

Objectives : The aim of this study was to confirm whether or not coral has a preventive effect on development of atopic dermatitis induced by house mite(dermatophagoides pteronyssinus) in NC/Nga mice. Methods : This study was undertaken by using a reliable Atopic dermatitis mouse model demonstrating similar immune response. Lobophytum crassum was administered orally to NC/Nga mouse for 3 weeks. In order to verify the effectiveness of Lobophytum crassum in atopic dermatitis treatment, its role in immune factors were observed in NC/Nga mice. Results : ALT, AST, BUN and creatine levels were all within in the normal ranges in MC-1 200 and 400 (mg/kg) treated groups, indicating no induced toxicity. MC-1 200 and 400 (mg/kg) groups decreased of atopic dermatitis skin manifestation in NC/Nga mouse of MC-1 200 and 400 (mg/kg) groups compared to that of the control group and decreased the ratio of WBC and lymphocyte in blood. Also, MC-1 200 and 400 (mg/kg) groups significant decreased the ratio of CD4+, CD8+, CD11b+/Gr1+, B220/CD23 and CD4/CD25 immune cell ratio in ALN. Finally MC-1 200 and 400 (mg/kg) groups significantly increased the ratio of CD4+, CD8+, B220/CD23 and CD4/CD25 immune cells in DLN. Conclusions : Theses results suggested that Lobophytum crassum has suppressive effects on aberrant and overactive immunological activities in dermatophagoides pteronyssinus-induced dermatitis mice of NC/Nga.

• International Journal of Industrial Entomology and Biomaterials
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• 제22권1호
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• pp.25-28
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• 2011

The virulence against the two-spotted spider mite, Tetranychus urticae Koch, was evaluated with entomopathogenic fungus Paecilomyces lilacinus (Thom) Samson HY-4 which is isolated from coleopteran insect and registered to Korean and US patents. Virulence tests were conducted with conidial suspensions ($1.5{\times}10^6conidia/ml$) of P. lilacinus HY-4 against T. urticae adults and positive results were recorded in laboratory conditions. The spraying device was also developed for the efficient and exact evaluation of treatment. The developed spraying device was named as SD-tower sprayer and its efficacy of spraying conidia was evaluated. The accumulated mortality caused by P. lilacinus HY-4 using SD-tower spray was about 73% at 6 days after inoculation. This suggest that the isolate P. lilacinus HY-4 may be considered as promising for a new approach to prevent adult infestations by T. urticae.

• Journal of Applied Biological Chemistry
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• 제59권2호
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• pp.125-128
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• 2016

The chemical compositions of the essential oil extracted from Albizziae julibrissin barks were analyzed by Gas chromatography-Mass spectrometry spectrometry. Fourteen components were identified, representing 89.23 % of the total oil composition. The analysis of the essential oil revealed that the essential oil contains 14 compounds, accounting for 89.23 % of the total oil. Hexanoic acid was the principal component (41.43 %) of the essential oil, followed by 4,4,6-trimethyl-cyclohex-2-en-1-ol (11.16 %), palmitic acid (9.00 %), 2-pentylfuran (5.66 %), 2-butyl-2-octenal (4.12 %), linoleic acid (3.10%), amyl hexanoate (3.01%), (E,E)-2,4-decadienal (2.49 %), 2-hexylthiophene (2.47 %), caprylic acid (2.13 %), ${\delta}-undecalactone$ (1.52 %), heptanoic acid (1.27 %), 3,5-octadien-2-ol (0.99 %), and 2-octenal (0.88 %). The acaricidal activity of the A. julibrissin oil was tested against Dermatophagoides farina, D. pteronyssinus and Tyrophagus putrescentiae by the fumigant bioassay. Based on the $LD_{50}$ values, the essential oil exhibited strong acaricidal activities against D. farinae ($LD_{50}$, $4.88{\mu}g/cm^3$), D. pteronyssinus ($2.44{\mu}g/cm^3$), and T. putrescentiae ($1.22{\mu}g/cm^3$). These results indicate that A. julibrissin oil could be a source of acaricidal agents for mite control.

• Allergy, Asthma & Immunology Research
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• 제10권6호
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• pp.686-697
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• 2018

Purpose: Several markers for eosinophilic inflammation have been proposed to predict response to asthma treatment. However, definitive criteria for treatment decisions have not yet been established. We investigate a potentially useful relatively non-invasive biomarker, eosinophil-derived neurotoxin (EDN), to predict favorable responses to budesonide or montelukast, common treatment for children with asthma. Methods: Young children (1 to 6 years old) were enrolled in this randomized, parallel, 2-group, open-label trial. Criteria for eligibility included: 1) being symptomatic during the run-in period; and 2) having a serum EDN (sEDN) level ${\geq}53ng/mL$, with positive specific immunoglobulin E to house dust mite. Eligible patients were randomly placed into 2 groups: the BIS group received budesonide inhalation suspension (BIS) 0.5 mg once daily; the MONT group received montelukast 4 mg once daily. Ineligible patients were invited to receive montelukast 4 mg once daily (OBS group). Treatment period was 12 weeks. Results: Asthma control days increased significantly in the BIS and MONT groups (P < 0.000) over the 12-week study period. There was no significant change in sEDN in the BIS group but there was a significant decrease in the MONT group (P < 0.000). Patients in the OBS group with high EDN levels (> 53 ng/mL) showed a significant decrease due to MONT treatment (P = 0.023). Rescue medication usage significantly decreased in the BIS and MONT groups (P < 0.000). Conclusions: EDN is a useful relatively non-invasive biomarker for predicting responses to montelukast and budesonide treatment of preschool children with beta2-agonist responsive recurrent wheeze and multiple-trigger wheeze (Trial registry at UMIN Clinical Trials Registry, UMIN000008335).

• 한국잠사곤충학회지
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• 제50권2호
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• pp.109-111
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• 2012

성공적인 생물학적 방제를 위해서는 적용천적의 사육기준과 규격이 설정되어 있어야 한다. 8, $12^{\circ}C$, 습도 $70{\pm}5%$, 24시간 암조건에서 총채가시응애와 그 먹이응애인 긴털가루응애의 저온 저장 실험을 수행하였다. 긴털가루응애는 소맥피(50%)와 쌀겨(50%)로 조성된 먹이사료에 접종하여 $12^{\circ}C$에서 저온저장이 가능하였다. 긴털가루응애와 총채가시응애의 생존율이 70%되는 조건은 $12^{\circ}C$에서 28일, 70일 저장후이다. 총채가시응애를 $12^{\circ}C$에서 28, 56, 84일 저온 저장후 증식율을 확인한 결과 저온기간에 상관없이 유사한 결과를 나타내었다.

• 대한임상검사과학회지
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• 제52권4호
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• pp.364-371
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• 2020

질병관리본부에서는 매개체로 인한 전파 확산에 대처하고자 전국 권역별 기후변화 매개체 감시사업을 실시하고 있으며 일환으로 전북 진안지역의 쯔쯔가무시 매개체인 털진드기 분포 조사와 병원체 검사를 위해 채집기와 야생설치류 포획을 실시하였다. 털진드기 종 분류를 위해 9~12월 둘째주까지 매주 1회씩, 총 20개의 채집기를 이용하여 채집한 결과 총 개체수는 8종 611마리가 채집되었다. 종 분류 결과는 둥근혀털진드기(N. tamiyai) 434마리(71.0%)로 가장 많이 분리되었다. 야생설치류 포획으로 털진드기 채집은 66마리의 설치류를 포획해서 털진드기 총 3,050마리 채집되어 chigger index는 46.2로 나타났다. 월별 chigger index는 11월 206.1로 가장 높았다. 병원체 보유여부 검사결과 총 85개의 pools중 5월과 9월에 각각 1개의 pools에서 양성을 확인하였다. 이러한 결과는 쯔쯔가무시증 환자가 빈번히 발생하는 봄과 가을철의 시기와도 일치하였다.