• The Korean Journal of Applied Statistics
• /
• v.25 no.2
• /
• pp.279-291
• /
• 2012

When fitting a Cox proportional hazards model with missing covariates, it is inefficient to exclude observations with missing values in the analysis. Furthermore, if the missing-data mechanism is not Missing Completely At Random(MCAR), it may lead to biased parameter estimation. Many approaches have been suggested to handle the Cox proportional hazards model when covariates are sometimes missing, but they are based on the selection model. This paper suggest an approach to handle Cox proportional hazards model with missing covariates by using the pattern-mixture model (Little, 1993). The pattern-mixture model is expressed by the joint distribution of survival time and the missing-data mechanism. In the pattern-mixture model, many models can be considered by setting up various restrictions, and different results under various restrictions indicate the sensitivity of the model due to missing covariates. A simulation study was conducted to show the sensitivity of parameter estimation under different restrictions in a pattern-mixture model. The proposed approach was also applied to mouse leukemia data.

• Communications for Statistical Applications and Methods
• /
• v.22 no.6
• /
• pp.589-598
• /
• 2015

In longitudinal studies missing data are common and require a complicated analysis. There are two popular modeling frameworks, pattern mixture model (PMM) and selection models (SM) to analyze the missing data. We focus on the PMM and we also propose Bayesian pattern mixture models using generalized linear mixed models (GLMMs) for longitudinal binary data. Sensitivity analysis is used under the missing not at random assumption.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.23 no.6
• /
• pp.496-501
• /
• 2011

The missing data patterns of tidal elevation data in Korean coasts are analysed and provided. The missing interval of the data is displayed for all stations using the missing data indicator matrix in order to identify the overall missing pattern. The spatial and temporal missing rates are also estimated. The total missing rate of tidal elevation data is low. However, most of the missing is mainly derived from just 1 or 2 specific stations. The autocorrelation function of the consecutive missing interval data also shows that the missing interval occurs randomly.

• Ocean and Polar Research
• /
• v.44 no.2
• /
• pp.179-190
• /
• 2022

Data missing in optical satellite images caused by natural variations have been a crucial barrier in observing the status of marine surfaces. Although there have been many attempts to fill the gaps of non-observation, there is little research to analyze the ratio of missing grids to overall sea grids and their seasonal patterns. This report introduces the method of quantifying the distribution of missing points and then shows how the missing points have spatial correlation and seasonal trends. Both temporal and spatial integration methods are compared to assess the effectiveness of reducing missing data. The temporal integration shows more outstanding performance than the spatial integration. Moran's I and K-function with statistical hypothesis testing show that missing grids are clustered and there is a non-random distribution from daily integration. The result of the seasonality test for Moran's I through a periodogram shows dependency on full-year, half-year, and quarter-year periods respectively. These analysis results can be used to deduce appropriate integration periods with permissible estimation errors.

• Communications for Statistical Applications and Methods
• /
• v.12 no.2
• /
• pp.473-481
• /
• 2005

The testing problem for sphericity structure of the covariance matrix in a multivariate normal distribution is introduced when there is a sample with 2-step monotone missing data pattern. The maximum likelihood method is described to estimate the parameters on the basis of the sample. Using these estimates, the likelihood ratio criterion for testing sphericity is derived.

• The Korean Journal of Applied Statistics
• /
• v.33 no.3
• /
• pp.269-280
• /
• 2020

Time course gene expression data is a large amount of data observed over time in microarray experiments. This data can also simultaneously identify the level of gene expression. However, the experiment process is complex, resulting in frequent missing values due to various causes. In this paper, we propose a pattern consistency index adaptive nearest neighbors as a method of missing value imputation. This method combines the adaptive nearest neighbors (ANN) method that reflects local characteristics and the pattern consistency index that considers consistent degree for gene expression between observations over time points. We conducted a Monte Carlo simulation study to evaluate the usefulness of proposed the pattern consistency index adaptive nearest neighbors (PANN) method for two yeast time course data.

• The Korean Journal of Applied Statistics
• /
• v.16 no.2
• /
• pp.407-426
• /
• 2003

We consider the missing covariates problem in generalized estimating equations(GEE) model. If the covariate is partially missing, GEE can not be calculated. In this paper, we study the performance of 7 imputation methods to handle missing covariates in GEE models, and the properties of GEE estimators are investigated after missing covariates are imputed for ordinal data of repeated measurements. The 7 imputation methods include i) Naive Deletion ii) Sample Average Imputation iii) Row Average Imputation iv) Cross-wave Regression Imputation v) Carry-over Imputation vi) Bayesian Bootstrap vii) Approximate Bayesian Bootstrap. A Monte-Carlo simulation is used to compare the performance of these methods. For the missing mechanism generating the missing data, we assume ignorable nonresponse. Furthermore, we generate missing covariates with or without considering wave nonresp onse patterns.

• The Korean Journal of Applied Statistics
• /
• v.15 no.1
• /
• pp.33-43
• /
• 2002

Various kinds of estimation methods have been developed for imputation of categorical missing data. They include category method, logistic regression, and association rule. In this study, we propose two fusions algorithms based on both neural network and voting scheme that combine the results of individual imputation methods. A Mont-Carlo simulation is used to compare the performance of these methods. Five factors used to simulate the missing data pattern are (1) input-output function, (2) data size, (3) noise of input-output function (4) proportion of missing data, and (5) pattern of missing data. Experimental study results indicate the following: when the data size is small and missing data proportion is large, modal category method, association rule, and neural network based fusion have better performances than the other methods. However, when the data size is small and correlation between input and missing output is strong, logistic regression and neural network barred fusion algorithm appear better than the others. When data size is large with low missing data proportion, a large noise, and strong correlation between input and missing output, neural networks based fusion algorithm turns out to be the best choice.

• Journal of Preventive Medicine and Public Health
• /
• v.35 no.2
• /
• pp.136-140
• /
• 2002

Objectives : A common problem with analyzing survey data involves incomplete data with either a nonresponse or missing data. The mail questionnaire survey conducted for collecting lifestyle variables on the members of the Korean Elderly Phamacoepidemiologic Cohort(KEPEC) in 1996 contains some nonresponse or missing data. The proper statistical method was applied to evaluate the missing pattern of a specific KEPEC data, which had no missing data in the independent variable and missing data in the response variable, BMI. Methods : The number of study subjects was 8,689 elderly people. Initially, the BMI and significant variables that influenced the BMI were categorized. After fitting the log-linear model, the probabilities of the people on each category were estimated. The EM algorithm was implemented using a log-linear model to determine the missing mechanism causing the nonresponse. Results : Age, smoking status, and a preference of spicy hot food were chosen as variables that influenced the BMI. As a result of fitting the nonignorable and ignorable nonresponse log-linear model considering these variables, the difference in the deviance in these two models was 0.0034(df=1). Conclusion : There is a lot of risk if an inference regarding the variables and large samples is made without considering the pattern of missing data. On the basis of these results, the missing data occurring in the BMI is the ignorable nonresponse. Therefore, when analyzing the BMI in KEPEC data, the inference can be made about the data without considering the missing data.

• The Korean Journal of Applied Statistics
• /
• v.29 no.3
• /
• pp.539-547
• /
• 2016

We discussed how to handle missing binary data clinical trials. Patterns of occurring missing data are discussed and introduce missing binary data imputation methods that include the modified method. A simulation is performed by modifying actual data for each method. The condition of this simulation is controlled by a response rate and a missing value rate. We list the simulation results for each method and discussed them at the end of this paper.