• 아시아태평양코퍼스연구
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• 제3권1호
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• pp.1-20
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• 2022

As a milestone progression in China's space exploration history, Chang'e Project has attracted a lot of media attention since its first launching. This study aims to examine and compare the similarities and differences between the Chinese media and the British media in using nouns, verbs, and adjectives to report the Chang'e Project. After categorising the documents based on specific project phases, we created two diachronic corpora to explore the linguistic shifts and similarities and differences of diction employed by the Chinese and British media on the Chang'e Project ideology. This longitudinal study was performed with Lancsbox and the CLAWS web tagger through critical discourse analysis as the theoretical framework. The findings of the current study showed that the Chang'e Project coverage in both media increased on an annual basis, especially after 2019. In contrast to the objectivity and positivity in the Chinese Media, the British Media seemed to be more subjective with more appraisal adjectives in the news reports. Nonetheless, both countries were trying to be objective and formal in choosing nouns and verbs. Ideology-wise, the Chinese news media reports portrayed more positivity on domestic circumstances while the British counterpart was typically more critical. Notably, the study outcomes could catalyse future research on the Chang'e Project and facilitate diplomatic policies.

• Nutrition Research and Practice
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• 제17권4호
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• pp.597-615
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• 2023

Healthy aging can be defined as an extended lifespan and health span. Nutrition has been regarded as an important factor in healthy aging, because nutrients, bioactive food components, and diets have demonstrated beneficial effects on aging hallmarks such as oxidative stress, mitochondrial function, apoptosis and autophagy, genomic stability, and immune function. Nutrition also plays a role in epigenetic regulation of gene expression, and DNA methylation is the most extensively investigated epigenetic phenomenon in aging. Interestingly, age-associated DNA methylation can be modulated by one-carbon metabolism or inhibition of DNA methyltransferases. One-carbon metabolism ultimately controls the balance between the universal methyl donor S-adenosylmethionine and the methyltransferase inhibitor S-adenosylhomocysteine. Water-soluble B-vitamins such as folate, vitamin B6, and vitamin B12 serve as coenzymes for multiple steps in one-carbon metabolism, whereas methionine, choline, betaine, and serine act as methyl donors. Thus, these one-carbon nutrients can modify age-associated DNA methylation and subsequently alter the age-associated physiologic and pathologic processes. We cannot elude aging per se but we may at least change age-associated DNA methylation, which could mitigate age-associated diseases and disorders.

• Asian-Australasian Journal of Animal Sciences
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• 제13권6호
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• pp.856-860
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• 2000

Cloning technology continues to capture widespread attention by the international news media and biomedical and agricultural industries. The future uses of this technology could potentially contribute to major advances in biomedical and agricultural sciences. Cloned transgenic dairy cattle possessing milk promoters directing transgenes will produce pharmaceutical proteins in their milk faster, more efficiently and less expensively than transgenic cattle created using microinjection techniques. Additionally, cloned transgenic fetuses and animals may become a source of cells, tissue and organs for xenotransplantation. Lastly, but maybe most importantly, enhanced production traits and disease resistance may be realized in animal agriculture by utilizing these new technologies. The recent advances in the cattle cloning technology are important but there are still major obstacles preventing widespread commercial use of this technology. The type of donor nucleus, recipient cytoplasm, and cloning procedures used will impact the potential number of clones produced and the uses of the technology. In addition, the new advances in cloning methodology have not improved the relatively low pregnancy rates or reduced the incidence of health problems observed in cloned offspring. These problems may require novel techniques to decipher their cause and new methods of preventing and/or diagnosing them in the preimplantation embryo. The commercial potential is enormous for cloning technology; however, little has been done to improve the efficiencies of the procedure. Improving procedural efficiencies is a critical developmental milestone especially for potential uses of cloning technology in animal agriculture.

• Parasites, Hosts and Diseases
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• 제52권2호
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• pp.143-149
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• 2014

To evaluate the seroprevalence against circumsporozoite protein (CSP) of Plasmodium vivax in sera of Korean patients, the central repeating domain (CRD) of CSP was cloned and analyzed. From the genomic DNA of patient's blood, 2 kinds of CSPs were identified to belong to a VK210 type, which is the dominant repeating of GDRA(D/A)GQPA, and named as PvCSPA and PvCSPB. Recombinantly expressed his-tagged PvCSPA or PvCSPB in Escherichia coli reacted well against sera of patients in western blot, with the detecting rate of 47.9% (58/121), which included 15 cases positive for PvCSPA, 6 cases positive for PvCSPB, and 37 cases for both. The mixture of PvCSPA and PvCSPB was loaded to a rapid diagnostic test kit (RDT) and applied with the same set of patient sera, which resulted in detection rates of 57.0% (69/121). When the protein sequences of PvCSPA were compared with those of P. vivax in endemic regions of India and Uganda, they were compatibly homologous to PvCSPA with minor mutations. These results suggested that the recombinant PvCSPA and PvCSPB loaded RDT may be a milestone in latent diagnosis which has been a hot issue of domestic malaria and important for radical therapy in overlapped infections with P. falciparum in tropical and subtropical areas. During the biological process of malarial infection, exposure of CSP to antigen-antibody reaction up to 57.0% is the first report in Korea.

• 디지털융복합연구
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• 제10권3호
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• pp.51-58
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• 2012

본 연구에서는 경영혁신전략의 하나로 구축 운용되어 왔던 공급사슬관리시스템(SCM)의 핵심적인 성공요인을 도출하였고, 이들 성공요인들 사이의 중요도를 기반으로 한 우선순위를 결정하기 위하여 계층적분석기법(AHP)을 실시하였다. 공급사슬관리시스템의 핵심성공요인의 도출을 위해서는 국내 상장기업 중 공급망관리시스템을 구축 운영하고 있는 기업을 대상으로 인터넷 설문조사를 실시하였고, 수집된 데이터로 실증분석을 하였다. 실증분석 결과 SCM의 주요성공요인은 경영조직요인, 정보기술요인, 외부환경요인 그리고 성과 및 변화관리요인으로 함축되었다. 이들 요인들을 AHP 기법을 통해 우선순위를 분석한 결과로 "IT기술인프라" 요인이 성공요인들 중 우선순위가 가장 높았다. 본 연구의 결과는 한국 제조업들의 공급사슬관리에 있어서 구축 및 관리 방향을 제시해 줄 것으로 판단된다.

• 한국디지털정책학회:학술대회논문집
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• 한국디지털정책학회 2004년도 International Conference on Digital Policy & Management
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• pp.39-53
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• 2004

Data production systems are generally very large, distributed and complex systems used for creating advanced (mainly statistical) reports. Typically, data is gathered periodically and then subsequently aggregated and separated during numerous production steps. These production steps are arranged in a specific sequence (workflow or production chain), and can be located worldwide. Today, a need for improving and automating methods of supervision for data production systems has been recognized. Supervision in this context entails planning, monitoring and controlling data production. Two significant approaches are introduced here for improving this supervision. The first is a 'closely-coupledd' approach (meaning direct communication between production jobs and supervisory tool, informing the supervisory tod immediately about delays in production) - based upon traditional production planning methods typically used for manufacturing (goods) and adopted for working with data production. The second is a 'loosely-coupled' approach (meaning no direct communication between supervisory tool and production jobs is used) - having its origins in proven traditional project management. The supervisory tool just enquires continuously the progress of production. In both cases, dates, costs, resources, and system health information is made available to management. production operators and administrators to support a timely and smooth production of periodic data. Both approaches are theoretically described and compared. The main finding is that, both are useful, but in different cases. The main advantages of the closely coupled approach are the large production optimisation potential and a production overview in form of a job execution plan, whereas the loosely coupled method mainly supports unhindered job execution and offers a sophisticated production overview in form of a milestone schedule. Ideas for further research include investigation of other potential approaches and theoretical and practical comparison.

• 보건교육건강증진학회지
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• 제18권2호
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• pp.97-113
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• 2001

At the opening of a new millennium and a new century, health promotion and education services in Korea are in the early developmental stage. The National Health Promotion Act legislated in 1995 was a milestone for initiating a national and local health promotion program in Korea. And since then local governments and health centers have been developing and providing health promotion program for the community populations. The short history of health promotion and education in Korea has meant that local governments and health centers have a limited experience and organizational capacity for health promotion and education planing and practice. This study was attempted to measure health education need of rural community and to analyze the factors for health education need assessment. Surveyors interviewed 1250 subjects randomly selected. Subjects were 2.17% of men and women in Changnyung county and older then 20 years old. Data were collected from April 17, 2000 through April 27, 2000. The questionnaire consisted of general characteristics, health educational experiences, health educational method, health educational content and health educational needs for rural community residents. The questions on the health educational needs of content consist of 36 questions in 8 fields. The statistical methods used for the analysis were $X^2$-test, t-test, F-ratio and ANOVA using SPSS program. In conclusion, despite more needs to the respondents who are in the low education level and socioeconomic state, in the old age, in the low health knowledge, they required less health education. To enjoy a more healthy life after more community residents actively understand and are interested in health education and health promotion, we certainly require a designed and systemic health education. The resources of health department in Korea are limited and the investment involved in health promotion and health education is severely reduced. Particularly this situation is more severe in the rural community. To select and perform an effective health education methods that the nature and reality of the rural community are considered, well use the resources to invest in health promotion affairs as effectively as possible and then they will take the responsibility of healthy community.

• 한국산학기술학회논문지
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• 제11권10호
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• pp.3733-3739
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• 2010

본 논문의 연구목적은 의료기관에서의 경영성과측정에 사용하는데 사용되는 성과 요인들의 우선순위를 연구하고자 하는데 있다. 이를 위하여 계층분석기법을 사용하였다. 또한 의료기관의 경영성과를 측정하는 성과측정요인과 그에 따른 핵심성과 요인(Key Performance Indicator : KPI)은 Kaplan과 Norton의 균형성과표(BSC) 측정방식을 응용하였다. 이를 위해서 연구자는 실험적이고 확정적인 요인 분석을 실시하여 성과측정요인을 생성하였고, 이들 측정요인들의 신뢰성과 타당성을 조사하였다. 92개 종합병원급 의료기관 중에서 56개의 병원으로부터 유효한 설문지에 대한 답을 얻었다. 요인분석으로 성과측정지표를 개발한 후에는 이들 요인들 사이의 우선순위를 결정하기 위하여 계층분석기법(AHP)을 사용하였다. AHP 분석의 결과로 우리는 성과측정요인과 그의 핵심성과지표들의 중요도에 따라 정렬된 리스트를 볼 수 있었다. 본 연구의 결과는 급변하는 의료환경에서 각 의료기관들이 경쟁력을 확보하기 위한 경영전략의 하나로 채택하고 있는 경영성과분석 전략의 방향과 기준을 제시할 수 있다.

• 한국항해항만학회지
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• 제28권7호
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• pp.619-627
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• 2004

Introduction of wave model, considered the effect of shoaling, refraction, diffraction, partial reflection, bottom friction, breaking at the coastal waters of complex bathymetry, is a very important factor for most coastal engineering design and disaster prevention problems. As waves move from deeper waters to shallow coastal waters, the fundamental wave parameters will change and the wave energy is redistributed along wave crests due to the depth variation, the presence of islands, coastal protection structures, irregularities of the enclosing shore boundaries, and other geological features. Moreover, waves undergo severe change inside the surf zone where wave breaking occurs and in the regions where reflected waves from coastline and structural boundaries interact with the incident waves. Therefore, the application of mild-slope equation model in this field would help for understanding of wave transformation mechanism where many other models could not deal with up to now. The purpose of this study is to form a extended mild-slope equation wave model and make comparison and analysis on variation of harbor responses in the vicinities of Ulsan Harbor and Ulsan New Port, etc. due to construction of New Port in Ulsan Bay. We also considered the increase of water depth at the entrance channel by dredging work up to 15 meters depth in order to see the dredging effect. Among several model analyses, the nonlinear and breaking wave conditions are showed the most applicable results. This type of trial might be a milestone for port development in macro scale, where the induced impact analysis in the existing port due to the development could be easily neglected.

• 보건교육건강증진학회지
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• 제15권2호
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• pp.43-53
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• 1998

The National Health Promotion Law passed in 1995 was a milestone for initiating a national health promotion program in Korea, and government officers and health professionals are working on how to approach health promotion issues. The purpose of this study was to analyse methods and use of constructivist paradigm in health promotion and education. The health promotion area needs community empowerment, building community partnerships, and community capacity. To meet these health promotion requirements health promotion workforce should be trained through professional preparation programs that contains communication skills, group process skills, and management of programs in advanced countries such as the United States and Australia. Skills and responsibilities of those who are in charge of providing health promotion services have not yet been clearly defined in Korea because the area of health promotion is a multi-academic field, and needs a different approach, constructivist approach. Constructivist paradigm requires relativism, reasoning skills, collaborating, and motivation. These components are needed for community empowerment. Constructivism also has been applied to the field of education. Problem-based education, outcome-based education, performance-based education came from the constructivism. These educational methods are student-centered method. As the modernizing society becomes more complicated, traditional or conventional teacher-centered education cannot meet the needs of students. Students need to learn skills necessary to make healthy decisions with individual value system. So these interactive, self-learning methods can serve much more to the learner. Constructivist educational methods can be applied to educational programs in computers, too. To expand and differentiate the area of health education and health promotion from other health related fields, it is crucial to devote efforts in application and development of constructivist methods.