• Title/Summary/Keyword: migration process

Search Result 543, Processing Time 0.032 seconds

Ventral Fixation of Atlantoaxial Joint under Fluoroscopic Guidance Using Screws in a Chihuahua Dog (환축추 아탈구 견에서 투시기 유도를 통한 복측 나사 고정술)

  • Lee, Jae-Hoon;Yang, Hee-Taek;Yang, Wo-Jong;Chung, Dai-Jung;Kang, Eun-Hee;Eom, Ki-Dong;Choi, Chi-Bong;Chang, Hwa-Seok;Kim, Hwi-Yool
    • Journal of Veterinary Clinics
    • /
    • v.25 no.2
    • /
    • pp.131-135
    • /
    • 2008
  • A 5-year-old Chihuahua dog was evaluated for a tetraparesis. The dog was presented with a non-ambulatory tetraparesis and neck pain. Radiography demonstrated an atlantoaxial (AA) subluxation and increased distance between the dorsal arch of the C1 and the dorsal spinous process of the C2. The AA joint was fixed with ventral transarticular fixation using two screws under fluoroscopic guidance. Neck brace was applied during 3 weeks post-operation. After 4 weeks, the dog was fully ambulatory with improved neurological function. Postoperative radiographs confirmed reduction of the luxation and no migration of screws. The dog showed complete resolution of clinical signs without signs of recurrence till 4 months after operation. Proper angulations of screws provided under fluoroscopic guidance, enabled adequate stabilization of the AA joints using ventral transarticular screw fixation which improved neurologic outcome of the patient.

Crystal growth studies of $SF_6$ clathrate hydrate ($SF_6$ 하이드레이트 결정의 성장 특성에 대한 연구)

  • Lee, Yoon-Seok;Lee, Ju-Dong;Lee, Bo-Ram;Lee, Hyun-Ju;Lee, Eun-Kyung;Kim, Soo-Min;Kim, Young-Seok;Yoon, Seog-Young;Kim, Yang-Do
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.19 no.5
    • /
    • pp.228-236
    • /
    • 2009
  • In this study, we investigated morphological characteristics of $SF_6$ clathrate hydrate crystals to understand its formation and growth mechanism. $SF_6$ clathrate hydrate crystals were formed in high-pressure reaction cell charged with pure water and $SF_6$ gas at constant pressure and temperature. Two-phase ($SF_6$ gas/aqueous solution) and three-phase ($SF_6$ gas/aqueous solution/$SF_6$ liquid) conditions were investigated, In both conditions, dendritic shape hydrate crystals were grown as like fibriform crystals along upward growth direction at the gas/aqueous solution interface. In the case of the reaction process of three-phase condition, when the $SF_6$ gas bubbles which were generated in $SF_6$ liquid phase due to the reduction of reaction cell pressure stuck to the gas/aqueous interfaces, the hydrate phase were appeared at the surface of the bubbles. This paper presents the detail growth characteristics of $SF_6$ hydrate crystals including crystal nucleation, migration, growth and interference.

Periodontal Wound Healing of the Experimental Subepithelial Connective Tissue Graft in Dogs (성견의 실험적 상피하 결합조직 이식시의 치주조직의 치유)

  • Jung, Hyun-Chul;Choi, Seong-Ho;Cho, Kyoo-Sung;Chai, Jung-Kyi;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
    • /
    • v.27 no.2
    • /
    • pp.379-394
    • /
    • 1997
  • Several methods have been used for regeneration of tissue lost by periodontal disease. Subepithelial connective tissue graft technique, one of the technniques of mucogingival surgery, is used for the regeneration in esthetic problems such as recession, and denuded root coverage. This study is performed to evaluate the healing process and the regeneration and reattachment of periodontal tissue, including the reconstruction of junctional epithelium, and connective tissue. Alveolar defects in five adult dogs were treated with periodontal surgery and were attained by removing the marginal alveolar bone by $4{\time}3mm$ from CEJ in the labial side of incisors, and root surfaces were planed. The experimental sites were divided into two groups as follows. 1. root planing alone(control group) 2. with connective tissue graft (Experimental Group) In the two groups flaps were positioned and sutured tightly, the healing processes were observed and were histologically compared with each other after 2days, 4days, 1week, 2weeks, 4weeks. The results were obtained as follows : 1. In the two groups blood clots were observed as early as 2 and 4 days, and were resorbed at 1 week. 2. In the two groups moderate inflammation was observed as early as 2 and 4 days, decreased at 1 and 2 weeks, and disappeared at 4 weeks. 3. Junctional Epithelium migration was more significant in the control group, and was restrained by graft materials in the experimental group. 4. Features of connective tissue fiber attachment partially showed the parallel pattern in the two groups from 2 weeks, and entirely from 4weeks. 5. Anastomosis, between graft and connective tissue, appeared from 4 days in the experimental group and the border between them was not discriminated at 4weeks.

  • PDF

Tumor-Derived Transforming Growth Factor-β is Critical for Tumor Progression and Evasion from Immune Surveillance

  • Li, Zheng;Zhang, Li-Juan;Zhang, Hong-Ru;Tian, Gao-Fei;Tian, Jun;Mao, Xiao-Li;Jia, Zheng-Hu;Meng, Zi-Yu;Zhao, Li-Qing;Yin, Zhi-Nan;Wu, Zhen-Zhou
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.13
    • /
    • pp.5181-5186
    • /
    • 2014
  • Tumors have evolved numerous mechanisms by which they can escape from immune surveillance. One of these is to produce immunosuppressive cytokines. Transforming growth factor-${\beta}$(TGF-${\beta}$) is a pleiotropic cytokine with a crucial function in mediating immune suppression, especially in the tumor microenvironment. TGF-${\beta}$ produced by T cells has been demonstrated as an important factor for suppressing antitumor immune responses, but the role of tumor-derived TGF-${\beta}$ in this process is poorly understood. In this study, we demonstrated that knockdown of tumor-derived TGF-${\beta}$ using shRNA resulted in dramatically reduced tumor size, slowing tumor formation, prolonging survival rate of tumor-bearing mice and inhibiting metastasis. We revealed possible underlying mechanisms as reducing the number of myeloid-derived suppressor cells (MDSC) and $CD4^+Foxp3^+$ Treg cells, and consequently enhanced IFN-${\gamma}$ production by CTLs. Knockdown of tumor-derived TGF-${\beta}$ also significantly reduced the conversion of na$\ddot{i}$ve $CD4^+$ T cells into Treg cells in vitro. Finally, we found that knockdown of TGF-${\beta}$ suppressed cell migration, but did not change the proliferation and apoptosis of tumor cells in vitro. In summary, our study provided evidence that tumor-derived TGF-${\beta}$ is a critical factor for tumor progression and evasion of immune surveillance, and blocking tumor-derived TGF-${\beta}$ may serve as a potential therapeutic approach for cancer.

An Empirical Study of SNS Users' Switching Intention Toward Closed SNS (SNS 이용자의 폐쇄형 SNS로의 전환의도에 영향을 미치는 요인에 관한 연구)

  • Park, Hyunsun;Kim, Sanghyun
    • Information Systems Review
    • /
    • v.16 no.3
    • /
    • pp.135-160
    • /
    • 2014
  • Most Social Network Service (SNS) provide online chat, video and file sharing, blogging and others. Because of this advantage, people depend on SNS to communicate with others. However, recently SNS encourage people to reveal too much information broadly so SNS users are concerned about privacy invasion and data spill. They also feel fatigue in process of touching people they don't know while using SNSs. That is the reason why they attempt to switch from opened SNS to Closed SNS. Therefore, the purpose of this study is to empirically investigate and analyze the effect of the factors on the SNS users' switching behavior when using SNS. To accomplish this purpose, this research adopted "Push-Pull-Mooring (PPM)" framework. The PPM is proposed by population geologist, who used it to explain the incentives of demographic migration. Following PPM model, this research empirically examines the three categories of antecedents for SNS switching intention toward closed SNS: push (i.e., weak connection, privacy concern, relative complexity), pull (i.e., enjoyment, belongingness, peer influence), mooring (i.e., SNS fatigue, user resistance) factors. The survey was conducted for 285 users on SNS communities in Korea. The results of this study are as follows; First, wear connection and privacy concern are significantly related to SNS switching intention. Second, enjoyment and belongingness are significantly related to SNS switching intention. Finally, the results show that SNS fatigue has a moderating effect on the links between push factors and SNS switching Intention. Also, user resistance has a moderating effect on the links between pull factors and SNS switching Intention. These findings contribute to the SNS literature both theoretically and practically.

Effects of Bird Ingestion on Seed Dispersal and Germination of the Elaeagnus macrophylla (보리밥나무(Elaeagnus macrophylla)의 종자 산포와 발아율에 미치는 조류의 영향)

  • Choi, Chang-Yong;Chae, Hee-Young
    • Journal of Korean Society of Forest Science
    • /
    • v.96 no.6
    • /
    • pp.633-638
    • /
    • 2007
  • The Elaeagnus macrophylla is a stenoecious evergreen plant with nitrogen-fixing symbionts and its timing of fruit-ripening coincides with spring migration of many birds in southwestern Korea. To recognize bird species which eat fleshy fruits of the Elaeagnus macrophylla and to evaluate the effects of bird ingestion on seed germination and dispersal, we monitored birds and carried out germination experiments using its fruits and seeds from March to April 2007 at Hongdo Island, Jeonnam Province, Korea. As a result, eight species of birds including the Gray Starling (Sturnus cineraceus), the Brown-eared Bulbul (Hypsipetes amaurotis) and the Dusky Thrush (Turdus naumanni) ingested the fruits. Germination rate was enhanced but length of seed dormancy was instead shortened in ingested (collected from the feces of birds) and manually extracted seeds (obtained directly from the fruits) than in intact fruits collected directly from the plant. Moreover, the possible scale of seed dispersal by the frugivorous birds ranged up to 6.9 ha based on home ranges of starlings. Consequently, the Elaeagnus macrophylla supplies food resources for migratory birds, and the birds give the plant opportunities of new colonization. We suggest that this kind of interaction between the nitrogen-fixing plant and avian seed dispersers is applicable as a process of natural restoration in degraded coastal evergreen forests.

Are Neutrophil/Lymphocyte and Platelet/Lymphocyte Rates in Patients with Non-Small Cell Lung Cancer Associated with Treatment Response and Prognosis?

  • Unal, Dilek;Eroglu, Celalettin;Kurtul, Neslihan;Oguz, Arzu;Tasdemir, Arzu
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.9
    • /
    • pp.5237-5242
    • /
    • 2013
  • Background: Inflammation is a critical component of tumor progression. Many cancers arise from sites of infection, chronic irritation, and inflammation. It is now becoming clear that the tumour microenvironment, which is largely orchestrated by inflammatory cells, is an essential participant in the neoplastic process, promoting proliferation, survival and migration. Platelets can release some growth factors such as platelet-derived growth factor, platelet factor 4, and thrombospondin. Such factors have been shown to promote hematogenous tumour spread, tumor cell adhesion and invasion, and angiogenesis and to play an important role in tumor progression. In this study, we aimed to investigate effects of the pretreatment neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) on survival and response to chemoradiotherapy in patients with non-small-cell lung cancer (NSCLC). Materials and Methods: Ninety-four patients with non-metastatic NSCLC were included and separated into two groups according to median valuse of NLR and PLR (low:<3.44 or high:${\geq}3.44$ and low:<194 or high${\geq}194$, respectively). Results: Pretreatment high NLR and PLR were associated with significantly shorter disease-free and overall survival rates. Multivariate analysis revealed that the overall survival rates were significantly linked with PLR (OR: 1.87, CI: 1.20-2.91, p: 0.006) and response to chemoradiotherapy (OR: 1.80, CI: 1.14-2.81, p: 0.012) and the disease-free survival rates were significantly associated with NLR (OR: 1.81, CI: 1.16-2.82, p: 0.009) and response to chemoradiotherapy (OR: 2.30, CI: 1.45-3.66, p: 0.001). There was no significant difference between patients with high and low NLR in terms of response to chemoradiotherapy. Similarly, there was no significant influence of the PLR. Conclusions: Pretreatment NLR and PLR measurements can provide important prognostic results in patients with NSCLC and assessment of the two parameters together appears to better predict the prognosis in patients with NSCLC. The effect of inflammation, indicators of NLR and PLR, on survival seems independent of the response to chemoradiotherapy.

Overcoming the Discourse of Foreignness: A Study on Class Positionality and Dual Identity of Korean Housemaids and Korean-Chinese Domestic Workers (외국인 담론 극복하기: 식모와 조선족 입주 가사노동자의 계급적 위치성과 이중적 정체성에 관한 연구)

  • Park, Soyoung
    • Journal of the Korean Geographical Society
    • /
    • v.50 no.2
    • /
    • pp.185-201
    • /
    • 2015
  • This paper suggests how Korean housemaids, called Sikmo, and Korean-Chinese migrant domestic workers have similar class positions and therefore form a dual identity in their interactions with female employers. rough spoken stories of the experiences of 27 females from Seoul, including Korean-Chinese domestic workers, Korean housemaids, and their employers, this research effectively overcomes the dichotomous discourse of natives versus foreigners. Instead it suggests the new interpretation that it is not foreignness but class inferiority of the domestic workers that plays a key role in establishing relationships with employers. Korean housemaids and Korean-Chinese domestic workers, both groups of whom are migrant workers, have developed coping strategies to enhance their labor value by spatially relocating themselves from their home society to a new society. They possess a similar labor status in women's history, being of low income, low education, and rural births. Consequently, these women experience 'translocal anchoring,' meaning their identities are intertwined with that of their home societies, and employers perceive them based on the characteristics of these places. The Korean employers perceive that the domestic workers' morality and intellectuality are inferior based on their class differences. This stigmatizing process leads employers to regard domestic workers as ambivalent people, not only threatening outsiders but also objects of pity, needing love and protection of their employers. The employers educate them culturally, teaching them skills to survive in the urban environment. These skills include cooking and language, in addition to advice on long-term plans to blend into society.

  • PDF

Characteristics of the Eggs and Larval Distribution and Transport Process in the Early Life Stage of the Chub Mackerel Scomber japonicus Near Korean Waters (한국 연근해에 분포하는 고등어(Scomber japonicus) 난·자치어의 분포특성 및 초기 수송과정 연구)

  • Kim, So Ra;Kim, Jung Jin;Stockhausen, William T.;Kim, Chang-Sin;Kang, Sukyung;Cha, Hyung Kee;Ji, Hwan-Sung;Jang, Seo-Ha;Baek, Hea Ja
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.52 no.6
    • /
    • pp.666-684
    • /
    • 2019
  • The horizontal distributions of eggs and larvae of chub mackerel Scomber japonicus were extensively surveyed in the vicinity of Korean waters between 31°75'N and 36°50'N during May and June in 2016 and 2017 (total of four surveys). We used a coupled bio-physical model (DisMELS) that combines an individual-based model (IBM) incorporating vertical migration of larvae and temperature-dependent survival to understand transport processes in the early life stage. Using the distributions of eggs and larvae from surveys, the potential spawning grounds were estimated at the northwest and southeast of Jeju Island and the central East China Sea in May, and at the southwestern East Sea and southern West Sea in June by running the model backward in time. In forward experiments within 30 days from the backward results, most larvae were transported to both the Korean and Japanese sides of the East Sea through the Korea Strait. However, the larvae released in the central East China Sea were transported to the Japanese side only, while those released in the southern West Sea were retained within that region. The survival rates at 30 days after release based on the simulation incorporating temperature-dependent survival throughout May and June were 29.7% in 2016 and 28.8% in 2017.

Print Mottle : Causes and Solutions from Paper Coating Industry Perspective

  • Lee, Hak-Lae
    • Journal of Korea Technical Association of The Pulp and Paper Industry
    • /
    • v.40 no.5
    • /
    • pp.60-69
    • /
    • 2008
  • The principal reasons for applying a pigment coating to paper are to improve appearance and printability. The pigment coating provides a surface that is more uniform and more receptive to printing ink than are the uncoated fibers and, in turn, both facilitates the printing process and enhances the graphic reproduction. The improvement in print quality is readily apparent, especially in image areas or when multiple colors are involved. Although pigment coating of paper is to improve the printability, coated paper is not completely free from printing defects. Actually there are a number printing defects that are observed only with the coated papers. Among the printing defects that are commonly observed for coated papers, print mottle during multi-color offset printing is one of the most concerned defects, and it appears not only on solid tone area but also half dot print area. There are four main causes of print mottle ranging from printing inks, dampening solution, paper, and printing press or its operation. These indicates that almost every factors associated with lithographic printing can cause print mottle. Among these variation of paper quality influences most significantly on print mottle problems in multicolor offset printing, and this indicates that paper is most often to be blamed for its product deficiency as far as print mottle problems are concerned. Furthermore, most of the print mottle problems associated with paper is observed when coated papers are printed. Uncoated papers rarely show mottling problems. This indicates that print mottle is the most serious quality problems of coated paper products. Overcoming the print mottle is becoming more difficult because the operating speeds of coating and printing machines are increasing, coating weights are decreasing, and the demands on high-quality printing are increasing. Print mottle in offset printing is caused by (a) nonuniform back trap of ink caused by a nonuniform rate of ink drying, referred as "back trap mottle, and (b) nonuniform absorption of the dampening solution. Furthermore, both forms of print mottle have some relationship to the structure of the coated layer. The surest way of eliminating ink mottling is to eliminate unevenness in the base paper. Coating solutions, often easier to put into practice, should, however, be considered. In this paper the principal factors influencing print mottle of coated papers will be discussed. Especially the importance of base paper roughness, binder migration, even consolidation of coating layers, control of the drying rate, types of binders, etc. will be described.