• Title/Summary/Keyword: microdosimetry

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Development and Characterization of Multi-Segmented Tissue Equivalent Proportional Counter for Microdosimetry (마이크로 도시메트리용 다분할 조직등가비례계수기의 개발과 특성 평가)

  • Nam, Uk-Won;Park, Won-Kee;Lee, Jaejin;Pyo, Jeonghyun;Moon, Bong-Kon;Moon, Myung Kook;Lim, Chang Hwy;Lee, Suhyun;Kim, Sunghwan
    • Journal of Sensor Science and Technology
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    • v.24 no.2
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    • pp.101-106
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    • 2015
  • We designed, developed and characterized a multi-segmented tissue equivalent proportional (TEPC) counter for microdosimetry. The energy resolution of the multi-segmented TEPC was about 12% for $^{241}Am$ 5.45 MeV alpha particles. The resolution was better than 33% for a single un-segmented TEPC. A compact and low power consumption TEPC could be made by using digital pulse processor (DPP). We also successfully calibrated the TEPC by using $^{252}Cf$ standard neutron source in Korea Research Institute of Standards and Science (KRISS). According to the results, the TEPC is useful for several application of radiation monitoring such as a neutron monitor, air crew monitor and space dosimeter.

Estimation of Relative Biological Effectiveness for Carbon Beam

  • Onizuka, Y.;Endo, S.;Takada, M.;Ishikawa, M.;Hoshi, M.;Uehara, S.;Hayabuchi, N.;Maeda, N.;Shizuma, K.
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.219-221
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    • 2002
  • In this work, single event spectra were measured in order to gain the microdosimetric parameters of some heavy ion radiotherapy fields at HIMAC. Microdosimetry is now a well-established technique for the investigation of complex mixed radiation field. Changes in frequency mean lineal energy y$\_$F/ as a function of thickness of A150 phantom were obtained. The absorbed dose was obtained by using y$\_$F/. A direct relation between this single event probability distribution and relative biological effectiveness (RBE) was assumed in order to estimate RBE using the response function.

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BETTER UNDERSTANDING OF THE BIOLOGICAL EFFECTS OF RADIATION BY MICROSCOPIC APPROACHES

  • Kim, Eun-Hee
    • Nuclear Engineering and Technology
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    • v.40 no.7
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    • pp.551-560
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    • 2008
  • Radiation has stochastic aspects in its generation, its choice of interaction mode during traveling in media, and its impact on living bodies. In certain circumstances, like in high dose environments resulting from low-LET radiation, the variance in its impact on a target volume is negligible. On the contrary, in low dose environments, especially when they are attributed to high-LET radiation, the impact on the target carries with it a large variance. This variation is more significant for smaller target volumes. Microdosimetric techniques, which have been developed to estimate the distribution of radiation energy deposited to cellular and subcellular-sized targets, contrast with macrodosimetric techniques which count only the average value. Since cells and DNA compounds are the critical targets in human bodies, microdosimetry, or dose estimation by microscopic approach, helps one better analyze the biological effects of radiation on the human body. By utilizing microbeam systems designed for individual cell irradiation, scientists have discovered that human cells exhibit radiosensitive reactions without being hit themselves (bystander effect). During the past 10 or more years, a new therapeutic protocol using discontinuous multiple micro-slit beams has been investigated for its clinical application. It has been suggested that the beneficial bystander effect is the essence of this protocol.

OVERVIEW OF HEALTH PHYSICS STUDIES ON TRITIUM BETA RADIATION (삼중수소 베타방사선에 관한 보건물리 연구의 적용)

  • Hwang, Sun-Tae;Hah, Suk-Ho
    • Progress in Medical Physics
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    • v.5 no.1
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    • pp.75-85
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    • 1994
  • As we enter the 2000s, there are four nuclear power units of the pressurized heavy water reactor-type in the commercial operation at the Wolsung Nuclear Power Plant(NPP) site where a larger amount of tritium ($\^$3/H) is released inevitably to the site environment. This radioctive nuclide is easily distributed throghout our environment because of its ubiquitous form as tritiated water (HTO) and its persistence in the environment. Tritum has certain characterisitics that present unique challenges for beta radiation dosimety and health risk assesment. In this paper, therefore, a variety of matters on tritium are considered and reviewed in terms of its characteristics and sources, metabolism and dosimetry, microdosimetry, radiobiology, risk assessment, and transport and cycling in the environment, etc.

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