• Title/Summary/Keyword: micro-sphere

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An Experimental Study on the Property of the Concrete with Glass Hollow Micro Sphere (유리질중공미소구체를 사용한 콘크리트의 특성에 관한 실험적 연구)

  • Kim, Sang-Heon;Kim, Se-Hwan;Park, Young-Shin;Jeon, Hyun-Gyu;Seo, Chee-Ho
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.3
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    • pp.160-166
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    • 2014
  • In this research, as a measure of reducing energy lost through external wall, we used Glass Hollow Micro Sphere (HMS) to improve insulation performance to structural concrete. The following is a result of experimenting concrete using HMS. As usage of HMS, decrease in slump arose and it is judged as a need of using superplasticizer. Replacement ratio increasing more and more, amount of air showed tendency to decrease and compressive strength decreased for interfacial adhesion had not been formed. as replacement ratio and unit volume decreased. It appears that thermal conductivity decreased about 30.0~46.5 percent as compared with normal weight concrete.

The MicroRNA-551a/MEF2C Axis Regulates the Survival and Sphere Formation of Cancer Cells in Response to 5-Fluorouracil

  • Kang, Hoin;Kim, Chongtae;Ji, Eunbyul;Ahn, Sojin;Jung, Myeongwoo;Hong, Youlim;Kim, WooK;Lee, Eun Kyung
    • Molecules and Cells
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    • v.42 no.2
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    • pp.175-182
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    • 2019
  • microRNAs regulate a diverse spectrum of cancer biology, including tumorigenesis, metastasis, stemness, and drug resistance. To investigate miRNA-mediated regulation of drug resistance, we characterized the resistant cell lines to 5-fluorouracil by inducing stable expression of miRNAs using lenti-miRNA library. Here, we demonstrate miR-551a as a novel factor regulating cell survival after 5-FU treatment. miR-551a-expressing cells (Hep3B-lenti-miR-551a) were resistant to 5-FU-induced cell death, and after 5-FU treatment, and showed significant increases in cell viability, cell survival, and sphere formation. It was further shown that myocyte-specific factor 2C is the direct target of miR-551a. Our results suggest that miR-551a plays a novel function in regulating 5-FU-induced cell death, and targeting miR-551a might be helpful to sensitize cells to anti-cancer drugs.

Automatic Segmentation of Trabecular Bone Based on Sphere Fitting for Micro-CT Bone Analysis (마이크로-CT 뼈 영상 분석을 위한 구 정합 기반 해면뼈의 자동 분할)

  • Kang, Sun Kyung;Kim, Young Un;Jung, Sung Tae
    • KIPS Transactions on Software and Data Engineering
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    • v.3 no.8
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    • pp.329-334
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    • 2014
  • In this study, a new method that automatically segments trabecular bone for its morphological analysis using micro-computed tomography imaging was proposed. In the proposed method, the bone region was extracted using a threshold value, and the outer boundary of the bone was detected. The sphere of maximum size with the corresponding voxel as the center was obtained by applying the sphere-fitting method to each voxel of the bone region. If this sphere includes the outer boundary of the bone, the voxels included in the sphere are classified as cortical bone; otherwise, they are classified as trabecular bone. The proposed method was applied to images of the distal femurs of 15 mice, and comparative experiments, with results manually divided by a person, were performed. Four morphological parameters-BV/TV, Tb.Th, Tb.Sp, and Tb.N-for the segmented trabecular bone were measured. The results were compared by regression analysis and the Bland-Altman method; BV/TV, Tb.Th, Tb.Sp, and Tb.N were all in the credible range. In addition, not only can the sphere-fitting method be simply implemented, but trabecular bone can also be divided precisely by using the three-dimensional information.

An Experimental Study on the Carbonation Resistance of Light Weight Concrete Utilizing Hollow glass Micro Sphere (유리질중공미소구체를 혼입한 경량콘크리트의 중성화 저항성에 관한 실험적 연구)

  • Choi, Young-Chul;Park, Young-Shin;Kim, Sang-Heon;Jeon, Hyun-Kyu;Seo, Chee-ho
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2014.05a
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    • pp.258-259
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    • 2014
  • Modern concrete high safety, constructability and economy due to advantages such as buildings used for more than about 70%, but due to the low thermal performance is essential, such as installation of additional insulation is required, and therefore increase the cost of construction, as well as the construction period and condensation Symptoms such as a domestic environment, such as to inhibit the problem by generating such an improvement has been desired. In this study, we want to present the base line data for the development of improved insulation performance concrete with analyzing and evaluating the Durable Properties of the concrete combination of hollow glass microsphere and lightweight aggregate.

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Evanescent Wave Coupled Laser in High-Q Microspheres (High-Q 마이크로스피어에서의 표면감쇠파 결합 레이저)

  • 최용석;안경원;문희종
    • Proceedings of the Optical Society of Korea Conference
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    • 2000.08a
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    • pp.82-83
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    • 2000
  • 굴절율이 외부보다 큰 실린더 (cylinder)나 스피어 (sphere)는 경계면에서의 전반사에 의해 손실이 매우 적은 high-Q 공진기가 될 수 있음이 잘 알려져 있다. 크기가 수 십 $mu extrm{m}$ 되는 실린더나 스피어에서의 공명모드는 편광(TM, TE), 모드 수 (mode number) n, 모드 순서 (mode order) l에 의해 정의되고 WGM (whispering gallery mode)라고도 불리워진다$^{(1)}$ . 모드 수n 이 클수록 모드 순서 l이 작을수록 공명모드의 Q 값은 큰 경향을 가진다. 액체 방울이나 액체 제트와 같이 열적 섭동에 민감한 마이크로 공진기 (micro-cavity)의 경우 Q값이 $10^{7}$ 정도로 제약되나, 실리카 마이크로 스피어 (micro-sphere)와 같은 고체 구에서 측정된 Q값은 약 $101^{10}$ 정도로 손실이 매우 적은 공진기가 될 수 있다$^{(2)}$ . 이와 같은 마이크로 공진기 특성을 이용하여 다양한 형태의 마이크로 공진기 레이저 대한 연구가 진행되어 왔다. 색소가 첨가된 고체구, 액체 방울, 액체 제트 등에서 기본적인 실험이 이루어졌고 반도체마이크로 스피어 구조에서 WGM 레이저$^{(3)}$ , polymer disc laser$^{(4)}$ , 광양자테 (photonic quantum ring)$^{(5)}$ 특성 연구 등이 실용가능성을 목표로 진행되고 있다. (중략)

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Analysis of electrical, thermal characteristic of Nano/Micro Epoxy composite (나노/마이크로 에폭시 복합체의 전기적, 열적특성 분석)

  • Jung, Eui-Hwan;Yoon, Jae-Hun;Lim, Kee-Joe;Jeong, Su-Hyun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2010.06a
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    • pp.99-99
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    • 2010
  • Polymer nanocomposite has been attracting much attention as a new insulation material, since homogeneous dispersion of nm-sized inorganic fillers can improve various properties significantly. In this paper, various kinds of epoxy based nanocomposites were made and AC breakdown strength of Nano-TiO2 and micro-silica filler mixture of epoxy based composites were studied by sphere to sphere electrode. Moreover, nano- and micro-filler combinations were adopted as an approach toward practical application of nanocomposite insulation materials. Nano-TiO2 particle size is about 10nm and composites ratio was resin (100) : hardener (82) : accelerator (1.5). AC breakdown test was performed at room temperature (25 [$^{\circ}C$], 80 [$^{\circ}C$] and 100 [$^{\circ}C$] in the vicinity of Tg (90[$^{\circ}C$]). And thermal conductivity were measured by ASTM-D5470.

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Thermal Insulation Property of UV Cure Coatings Using Hollow Micro-Spheres (마이크로 중공구를 이용한 자외선 경화 코팅 박막의 단열 특성)

  • Kim, Nam Yi;Chang, Young-Wook;Kim, Seong Woo
    • Korean Chemical Engineering Research
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    • v.50 no.4
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    • pp.621-626
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    • 2012
  • In this study, the composite coating materials with improved thermal insulation property were prepared by incorporating the hollow micro-spheres with high heat transfer resistance. The UV curable resin system consisting of hexa aliphatic urethane acrylate (UP118), trimethylolpropane triacrylate (TMPTA), 1,6-hexanediol diacrylate (HDDA), and photoinitiator (Irgacure184) was employed as an organic binder. The glass substrates were coated by the prepared composites via bar coating method and cured under UV radiation. The optical transparency, thermal insulation property, adhesion, and surface hardness of the glass coated with composites containing different type of micro-spheres were investigated. The incorporation of micro-spheres with only 20 vol% of content resulted in remarkable improvement in the thermal insulation property of the coated glass. In addition, the transparent coated glass with light transmittance of about 80% could be obtained when silica micro-sphere (SP) was used as a thermal barrier.

A Experimental Study on the Property of Lightweight Aggregate Concrete Using Hollow Micro Sphere (유리질 중공 미소 구체를 사용한 경량골재콘크리트의 특성에 관한 실험적 연구)

  • Kim, Sang Heon;Kim, Se Hwan;Park, Young Shin;Jeon, Hyun Gyu;Seo, Chee Ho
    • Journal of the Korea Institute of Building Construction
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    • v.15 no.2
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    • pp.177-183
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    • 2015
  • In this study, the thermal conductivity, physical and mechanical properties of lightweight aggregate concretes with hollow micro sphere(HMS) are experimentally examined as a basic research for the development of structural insulation concrete. As the results of this experiment, in the case of concrete mixed with HMS, the value of slump has been reduced, so it is found that the dosage of superplasticizer should be increased. As the replacement ratio of HMS increases, it has shown that the compressive strength is somewhat decreased due to the low interfacial adhesion strength of HMS. But the thermal conductivity is found to be greatly improved with the replacement ratio of HMS increases, the thermal conductivity of HMS shows the lower value of 68% at lightweight aggregate concrete and 32% of normal concrete. Also it is found that the compressive strength is decreased and thermal conductivity is increased as the water-cement ratio increases. The most outstanding for insulation performance is observed when using 20% of HMS and 50% of water-cement ratio.

Electrical and Mechanical Properties of Epoxy/Micro-sized Alumina Composite and the Effect of Nano-sized Alumina on Those Properties

  • Park, Jae-Jun;Shin, Seong-Sik;Yoon, Chan-Young;Lee, Jae-Young;Park, Joo-Eon
    • Transactions on Electrical and Electronic Materials
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    • v.16 no.5
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    • pp.260-263
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    • 2015
  • Epoxy/micro-sized alumina composite was prepared and the effects of alumina content on the electrical and mechanical properties were investigated in order to develop an insulation material for gas insulated switchgear (GIS). Nano-sized alumina (average particle size: 30 μm) was also incorporated into the epoxy/micro-sized alumina composite. An electrical insulation breakdown strength test was carried out in sphere-sphere electrodes and the data were estimated by Weibull statistical analysis. Tensile strength was measured at a crosshead speed of 10 mm/min using a universal testing machine. Alumina content was varied from 0 wt% to 70 wt%.). As micro-sized alumina content increased, insulation breakdown strength increased until 40 wt% alumina content and decreased after that content. The tensile strength of a neat epoxy system was 82.2 MPa and that value for 60 wt% alumina content was 91.8 MPa, which was 111.7% higher than inthe neat epoxy system. The insulation breakdown strength of micro-sized alumina (60 wt%)/nano-sized alumina (1 phr) glycerol diglycidyl ether (GDE) (1 phr) composite was 54.2 MPa, which was 116% higher than the strength of the system without nano-sized alumina.