• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1990년도 Proceedings of International Symposium on Korean Ginseng, 1990, Seoul, Korea
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• pp.20-24
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• 1990

The climacteric is that phase in the aging process during which a woman passes from the reproductive to the non-reproductive stage. The signals, such as hot flashes, vaso-motoric disturbances, perspiration, stiff shoulders, emotional symptoms, are refereed to as climacteric disturbances. Treatment of climacteric symptoms centers on estrogen replacement and transquilizers, but there are many problems to be solved to use these hormones/drugs as far as dosage, duration and complications are concerned. The care of women during the climacteric years should provide relief of distressing symptoms with as high a degree of safety as possible. From this viewpoint, we used red ginseng powder to those patients with high menopausal index successfully. We studied its mechanism of action and proved that red ginseng improved the micro-circulation system via improvement of erythrocyte deferability which enhanced sex steroidgenesis consequently

• Journal of Ginseng Research
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• 제14권2호
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• pp.162-166
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• 1990

The climacterium is that phase in the aging precess during which a woman passes from the reproductive to the non-reporductive stage. The signals, such as hot flashes, vaso-motoric disturbances, perspiration, stiff shoulders, emotinal symptoms, are refered to as climacteric disturbances. Treatment of climacteric symptoms centers around estrogen replacement and transfuilizers, but there are many problems to be solved to use these hormones/drugs as far as dossage, duration and complications are concerned. The care of women during the climacteric years should provide relief of distressing symptoms with as high a degree of safety as possible. From this view point, we used red ginseng powder to those patients with high menopausal index successfully. We studied its mechanism of action and proved that red ginseng improved the micro-circulation system via improvement of erythrocyte reformability which enhanced sex steroidgensis consequently.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.244-244
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• 2006

We developed novel polymer materials composed of thermoresponsive pNIPAAm main chain and photo-resnposive side chains of spirobenzopyran, and analyzed the photoresponsive characteristrics of the aqueous solutions of these copolymers. Further, we prepared various photoresponsive hydrogels composed of the copolymer, and investigated the effect of light irradiation on their properties. As a result, the copolymer exhibited quite unique response to light irradiation and the change in temperature and pH. Especially the drastic photo-induced dehydration was observed in low pH conditions, and photo-induced micro-relief formation was demonstrated using the hydrogel layer composed of the polymer.

• 산업기술연구
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• 제18권
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• pp.209-216
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• 1998

Some mechanical properties of the submerged arc-welded(SAW) zone between different kinds of metal (SS400+SB450) are investigated and compared with that between same kinds of metal (SS400+SS400 and SB450+SB450). The analysis of the chemical components and observation of the micro-structure by SEM of the weld zone are also carried out. And the effect of the stress relief annealing is examined by comparing tensile strength, elongation, toughness add hardness of SAW specimens before and after the heat treatment.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2009년도 춘계학술발표대회
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• pp.15.1-15.1
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• 2009

Nano transfer printing and micro contact printing is well known printing method based on soft lithography which uses conformal soft elastomer with designed surface relief structures. Here I introduce another class of novel 3D nanofabrication technique by using the same elastomer but in a different manner. The approach, which we refer to as proximity field nanopatterning, uses the surface-reliefed elastomers as phase masks to pattern thick layers of transparent, photosensitive materials. Aspects of the optics, the materials, and the physical chemistry associated with this method are outlined. A range of 3D structures illustrate its capabilities, and several application examples demonstrate possible areas of use in technologies ranging from microfluidics to photonic materials to density gradient structures for chemical release and high-energy density science.

• Radiation Oncology Journal
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• 제9권2호
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• pp.227-232
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• 1991

기관지 폐색으로 호흡곤란을 유발하는 기관지내 악성종양을 치료하기 위한 방사선 치료방법으로 고선량 기관지내 근접치료법이 본원에서 시행되었다. 기관지 내시경 시술을 이용하여 근접치료용 관을 기관지 내로 삽입하며 microSelectron HDR Ir-192를 이용하여 고선량 근접치료를 시행하였다. 이 논문에서 저자들의 경험을 소개하고 이 새로운 근접치료 시술이 효과적이면서도 외래 환자로 통근 치료도 가능할 정도로 용이하고 안전한 치료법으로 자세한 기술적 인 점을 설명하고자 한다.

• International Journal of Stem Cells
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• 제16권2호
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• pp.145-155
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• 2023

Background and Objectives: Embryologically, mesodermal development is closely related to the development of various organs such as muscles, blood vessels, and hearts, which are the main organs that make up the body. However, treatment for mesoderm developmental disorders caused by congenital or acquired factors has so far relied on surgery and drug treatment for symptom relief, and more fundamentally, treatment for mesoderm developmental disorders is needed. Methods and Results: In our study, microRNA (miRNA), which plays an important role in the mesoderm development process, was identified and the developmental function was evaluated. miRNAs consist of small nucleotides, which act as transcription factors that bind to the 3' untranslated region and suppressed target gene expression. We constructed the human embryonic stem cell (hESC) knockout cell line and analyzed the function and characteristics of miR-5739, which plays an important role in mesoderm lineage. miR-5739 acts as a transcription factor targeting SMA, Brachyury T, Hand1, which controls muscle proliferation and differentiation, and KDR gene, which regulates vessel formation in vitro. In vivo results suggest a role in regulating muscle proliferation and differentiation. Gene ontology analysis confirmed that the miR-5739 is closely related to genes that regulate muscle and vessel proliferation and differentiation. Importantly, abnormal expression of miR-5739 was detected in somatic cells derived from patients with congenital muscle disease. Conclusions: Our study demonstrate that miR-5739 gene function significantly affects transcriptional circuits that regulate muscle and vascular differentiation during embryonic development.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
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• pp.120.2-120.2
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• 2015

We propose a novel direct writing technique with a femtosecond laser enabling selective modification of not only the morphology of conducting polymer thin films but also the orientation and alignment of the polymer crystal. Surface relief gratings resulting from photoexpansion on P3HT:PCBM and PEDOT:PSS thin films were fabricated by femtosecond laser direct writing. The photoexpansion was induced at laser fluence below the ablation threshold of the thin film. The morphology (size and shape) of photoexpansion could be quantitatively controlled by laser writing parameters such as focused beam size, writing speed, and laser fluence. GIWAX results showed that face-on P3HT crystals were largely increased in the photoexpansion in comparison with pristine region of the thin film. In addition, the face-on P3HTs in the photoexpansion were aligned with their orientation along the polarization of the laser. The micro-RAMAN spectra confirmed that neither chemical composition change nor the polymer chain breaking was observable after femtosecond laser irradiation. We believe that this laser direct writing technique opens a new door to the fabrication of more efficient OPVs via non-contact, toxic-free approach.

• Asian Journal for Public Opinion Research
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• 제1권4호
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• pp.249-267
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• 2014

Social media is being increasingly utilized in disaster relief work to identify safety issues, locate displaced-victims, and seek or provide support for those who need help. The presence of social media in disaster management has changed significantly in recent years, as it was not prevalent in the 2008 Wenchuan earthquake, but had become a powerful force in the 2013 Ya'an earthquake. This paper discusses the development of social media in disaster management via making a comparison between how it functioned in the two earthquakes. It examines the following aspects: who are the stakeholders that use social media in the earthquake management; how do they adopt this means in response to the earthquakes; and what are the outcomes of adopting social media with regards to public engagement and collaboration in an emergency event. As Sina Weibo acts as the equivalent of China's Twitter, the methodology relies on an analysis of posts in Weibo. The outcomes primarily show that: (1) authorities, celebrities and the public actively adopted social media for the purpose of information dissemination and resource mobilization; and (2) social media users are both content consumers and content generators in the times of earthquakes. The study concludes that social media as a backchannel communication tool is helpful for government institutions, corporations, and nonprofit organizations to build relationships with their stakeholders in the disaster management cycle. The result will interest academics and emergency management practitioners who are concerned with improving disaster communication.

• Journal of Welding and Joining
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• 제2권2호
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• pp.54-61
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• 1984

Construction of welding structure is greatly dependent upon welding heat cycle. Fracture toughness is decreased remarkablely due to coarse grained HAZ and inequal residual stress of three dimensions to originate in welding. Post weld heat treatment(PWHT) is carried out to increase the fracture toughness of HAZ and to remove the residual stress. There occur some problem such as toughness decrement and stress relief cracking(SRC) in the coarse grained HAZ subject to the effect of tempering treatment. Therefore, in this paper, the effect of heat inputs affecting cooling rate and PWHT under the no stress on fracture toughness were evaluated by crack opening displacement (COD), SEM and micro-hardness test. Experimental results are as follows; 1. Fracture toughness of weld HAZ is dependent upon weld heat cycle and it is decreased with increment of heat input, but the degree of improvement of fracture toughness after PWHT was linearly increased with heat input. 2. Hardness of the parent metal is not changed, but the softening of coarse grained HAZ is remarkable due to PWHT. 3. Fracture surface of as-weld show the perfect brittle fracture with the cleavage fracture, but after PWHT they appear the ductile fracture surface with dimple.