• Title/Summary/Keyword: miR34a

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A Convergence Study on the Relationships between Self-Efficacy and Health Behavior in eldery women with chronic low back pain (만성 요통을 가진 여성 노인의 자기 효능감과 건강행위간의 관계에 대한 융합연구)

  • Park, Jum-mi;Shin, Na-yeon
    • Journal of the Korea Convergence Society
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    • v.9 no.2
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    • pp.43-50
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    • 2018
  • Purpose: The purpose of this study is to examine the relationships between self efficacy and health behavior of elderly woman with chronic low back pain. Methods: A descriptive correlational design was used and the participants were 130 eldery women patients with chronic low back pain from one general hospital in 2012. The structured questionnaire included Perceived Self Efficacy Scale, Health Behavior Assessment tool of the Korean Elders. Data analysis included t-test, ANOVA and Pearson's correlation. Results: The mean scores were $67.34{\pm}18.32$ for self efficacy, $99.70{\pm}14.46$ for health behavior. There were significant correlations between self efficacy and health behavior(r=.80). Conclusion: The findings suggest that elderly woman with chronic low back pain need nursing interventions to improve health behaviors by promoting self efficacy.

Comparison of Left Ventricular Volume and Function between 46 Channel Multi-detector Computed Tomography (MDCT) and Echocardiography (16 채널 Multi-detector 컴퓨터 단층촬영과 심초음파를 이용한 좌심실 용적과 기능의 비교)

  • Park, Chan-Beom;Cho, Min-Seob;Moon, Mi-Hyoung;Cho, Eun-Ju;Lee, Bae-Young;Kim, Chi-Kyung;Jin, Ung
    • Journal of Chest Surgery
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    • v.40 no.1 s.270
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    • pp.45-51
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    • 2007
  • Background: Although echocardiography is usually used for quantitative assessment of left ventricular function, the recently developed 16-slice multidetector computed tomography (MDCT) is not only capable of evaluating the coronary arteries but also left ventricular function. Therefore, the objective of our study was to compare the values of left ventricular function quantified by MDCT to those by echocardiography for evaluation of its regards to clinical applications. Material and Method: From 49 patients who underwent MDCT in our hospital from November 1, 2003 to January 31, 2005, we enrolled 20 patients who underwent echocardiography during the same period for this study. Left ventricular end-diastolic volume index (LVEDVI), left ventricular end-systolic volume index (LVESVI), stroke volume index (SVI), left ventricular mass index (LVMI), and ejection fraction (EF) were analyzed. Result: Average LVEDVI ($80.86{\pm}34.69mL$ for MDCT vs $60.23{\pm}29.06mL$ for Echocardiography, p<0.01), average LVESVI ($37.96{\pm}24.52mL$ for MDCT vs $25.68{\pm}16.57mL$ for Echocardiography, p<0.01), average SVI ($42.90{\pm}15.86mL$ for MDCT vs $34.54{\pm}17.94mL$ for Echocardiography, p<0.01), average LVMI ($72.14{\pm}25.35mL$ for MDCT vs $130.35{\pm}53.10mL$ for Echocardiography, p<0.01), and average EF ($55.63{\pm}12.91mL$ for MOCT vs $59.95{\pm}12.75ml$ for Echocardiography, p<0.05) showed significant difference between both groups. Average LVEDVI, average LVESVI, and average SVI were higher in MDCT, and average LVMI and average EF were higher in echocardiogram. Comparing correlation for each parameters between both groups, LVEDVI $(r^2=0.74,\;p<0.0001)$, LVESVI $(r^2=0.69,\;p<0.0001)$ and SVI $(r^2=0.55,\;p<0.0001)$ showed high relevance, LVMI $(r^2=0.84,\;p<0.0001)$ showed very high relevance, and $EF (r^2=0.45,\;p=0.0002)$ showed relatively high relevance. Conclusion: Quantitative assessment of left ventricular volume and function using 16-slice MDCT showed high relevance compared with echocardiography, therefore may be a feasible assessment method. However, because the average of each parameters showed significant difference, the absolute values between both studies may not be appropriate for clinical applications. Furthermore, considering the future development of MDCT, we expect to be able to easily evaluate the assessment of coronary artery stenosis along with left ventricular function in coronary artery disease patients.

The Influence of Nursing Students' Character Strength on Perceived Stress (간호대학생의 성격강점이 지각된 스트레스에 미치는 영향)

  • Yu, Mi-Ok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.168-176
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    • 2017
  • This is a descriptive study to determine the influence of character strength of nursing students on perceived stress. Data were collected from 174 nursing students in the A- area and analyzed using SPSS WIN 21.0 program. The character strength of nursing studentswas $3.46{\pm}.34$(on a 5-point scale) and perceived stress was $2.84{\pm}.42$(on a 5-point scale). Among the subdomains of character strengths, humanity was the highest,with a score of $3.65{\pm}.49$. The perceived stress of nursing students showed a negative correlation with character strength(r=-.50, p<.001) and was negatively correlated with all subdomains of character strength. In addition, the factor that most affected the perceived stress of nursing students-among general characteristics-was very difficult family experience (${\beta}=.146$, p=.026), and the factors with the greatest effect among the subdomains of character strengths were courage(${\beta}=-.250$, p=.006) and transcendence(${\beta}=-.275$, p=.013). These three factors were found to explain 39.5% of variance in perceived stress. Therefore, these results demonstrate the need to explore interventions that enable nursing school faculty and counseling staff to help confirm character strengths and reduce stress in students with hard time getting adjusted to nursing school.

Properities of Plastic film house soils and Physiological Disorder of Eggplant (시설가지 연작재배토양 이화학성이 생리장해과 발생에 미치는 영향)

  • Uhm, Mi-Jeong;Han, Soo-Gon;Kim, Kab-Cheol;Moon, Young-Hoon;Choi, Jeong-Sik
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.3
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    • pp.192-198
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    • 2001
  • This study was carried out to investigate the change of chemical properities and, microorganism due to continual cropping and to find the influences to physiological disordered eggplant fruits. Accumulation of soil nutrients seemed to be increased with the plastic film house duration and decreased with soil depth. The longer the period of eggplant cultivation duration, the lower the ratio of bacteria to fungi(B/F) and actinomycetes to the fungi(A/F) in rhizosphere soils. The soil EC and available $P_2O_5$ were significally correlated with the population densities of fungi($r=0.423^{**}$) and actinomycetes($r=0.438^{**}$), respectively. The ratio of split or drupaceous fruit showed tendency to increase with low soil moisture, and that of hypertrophy fruit showed tendency to increase in fields with longer cultivation years and high soil EC. The soil EC significally correlated with the ratio of hypertrophy fruit ($r=0.719^{**}$, Y=0.210X+0.578)and total physiological disordered fruits ($r=0.656^{**}$, Y=0.769X+7.097). And value of soil (Ca+Mg)/K was correlated with the ratio of physiologically disordered fruits($R^2=0.356^{*}$, Y=-1.333Ln(X)+12.26).

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Determination of β-Carotene in Infant Formulas by High-Performance Liquid Chromatography (HPLC를 이용한 조제유류 중 베타카로틴 함량 분석 연구)

  • Hwang, Kyung Mi;Bae, Ji Won;Hu, Soo Jung;Oh, Keum Soon
    • Journal of Food Hygiene and Safety
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    • v.34 no.4
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    • pp.334-339
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    • 2019
  • A procedure based on high-performance liquid chromatography (HPLC) is described to determine ${\beta}-carotene$ in infant formulas. The method for ${\beta}-carotene$ analysis was performed on a C18 reversed-phase column using acetonitrile/methanol/dichloromethane (6:1:3, v/v/v) as a mobile phase. ${\beta}-Carotene$ was determined in HPLC with photo diode array (PDA) detector. The parameters of validation were specificity, linearity, LOD, LOQ, accuracy, precision and repeatability. The specificity was confirmed by the retention time and the linearity ($R^2$), which was over 0.999 in the range of 0.125~2 mg/L. The detection and quantification limits were 0.064 and 0.193 mg/L, respectively. The accuracy and precision of this method using an STD spiked sample were 80~119% and 1.02~2.05% respectively. The method was applied to the analysis of various infant formula and follow-up formulas products containing ${\beta}-carotene$, and all the products contained acceptable levels of ${\beta}-carotene$ for nutrition labeling.

The Inhibitory Effects of Acanthopanax sessiliflorum Seeman on Melanogenesis (오가피추출물의 멜라닌 생성 저해 효과)

  • Im, Kyung-Ran;Kim, Mi-Jin;Jung, Taek-Kyu;Yoon, Kyung-Sup
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.34 no.2
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    • pp.149-156
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    • 2008
  • To develop a new natural whitening agent for cosmetics, we investigated effects of Acanthopanax sessiliflorum Seeman on melanogenesis. We prepared phenolic acid-rich extract including two phenolic acids, chlorogenic acid and caffeic acid, as predominant constituents from Acanthopanax sessiliflorum Seeman. Phenolic acid-rich extract showed ROS scavenging activities in 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical and xanthine/xanthine oxidase system with the $IC_{50}$ values of $3.43{\pm}0.35{\mu}g/mL$ and $158.91{\pm}1.57{\mu}g/mL$, respectively. Phenolic acid-rich fraction reduced melanin contents of B16 melanoma cells dose-dependantly and the decrease was $27.27{\pm}2.66%$ at a concentration of $100{\mu}g/mL$. And the phenolic acid-rich fraction reduced intracellular tyrosinase activity about $53.67{\pm}8.55%$ at a concentration of $100{\mu}g/mL$. Phenolic acid-rich extract inhibited tyrosinase and TRP-2 expression at protein level. These results suggest that phenolic acid-rich fraction reduced melanin formation by the inhibitions of tyrosinase activity and expression in B16 melanoma cells. Therefore, we suggest that phenolic acid-rich extract could be used as a whitening ingredient in cosmetics.

A Study on the Sleep Activity Pattern of the Infant (대구 지역 영아의 수면/활동 양상에 관한 연구)

  • Kim, Mi-Ye;Koh, Hyo-Jung;Shin, Young-Hee;Kim, Young-Hee;Oh, Jin-A;Kim, Hye-Young;Lee, Eun-Ju;Kim, Yong-Sook
    • Korean Parent-Child Health Journal
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    • v.3 no.2
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    • pp.1-17
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    • 2000
  • The purpose of this study was to recognized the sleep activity patterns of the normal infants in Korea. The subject were 41 normal infants who were below 8 weeks old and were born in Taegu city and Kyungbuk province. The measuring instrument the sleep activity was NCASA translated by the Korean-parent-child Health Academic Association. The data that were collected from April, 18 1999 to January 1, 2000 were analysed by the SPSS 7.5 program. The results of the study was summarized as follow; 1) The mean amount of total sleeping hours per day was decreased from $16.27{\pm}1.96$ hr at the 1st week, to $15.19{\pm}2.39$ hr at the 2nd week, to $13.66{\pm}2.40$ hr at the 3 week but increased to $16.55{\pm}5.77$ hr at the 4-8 week after birth. 2) The mean frequency of feeding was increased to $9.43{\pm}2.79$ times at the 3rd week but decreased to $7.55{\pm}1.23$ times at the 4-8th week after birth. 3) The regularity of day time sleep was decreased from 50.00% to 19.79% and that of night time sleep was increased from 51.79% to 72.92%. 4) The regularity of feeding was increased from 30.42% at the 1st week to 50.07% at the 2nd week but decreased 26.34% at the 4-8th week after birth. 5) The longest period of day time sleep was decreased to $2.39{\pm}0.42$ hr at the 3rd week but increased $2.47{\pm}0.69$ hr at the 4-8th week after birth. The longest period of night time sleep was decreased to $2.58{\pm}0.67$ hr at the 2nd week but increased to $3.00{\pm}1.32$ at the 3rd week and $4.30{\pm}1.16$ hr at the 4-8th week after birth. 6) At the 1st week, the 2nd week, the 3rd week after birth, the frequency of day time feeding was positively correlated with the frequency of night time feeding($R_{1week}=0.948^{**}$, $R_{2week}=0.927^{**}$, $R_{3week}=0.779^{**})$. At the 4-8th week after birth, the frequency of night time feeding was negatively correlated with the amount of night time sleep ($R_{4week-8week}=0.875^{*}$). On the basis of above findings, the following is suggested; It is need a longitudinal and transcultural study which are designed for children's sleep and feeding.

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Quality Variation of Domestic Wheat Compared to Imported Wheat Depending on Harvest Year (수확 연도별 우리밀과 수입밀의 품질 변이 비교)

  • Kwak, Han Sub;Kim, Tae Jong;Joo, Eun Young;Cha, Jang Hun;Kim, Ah Jin;Kim, Mi Jeong;Kim, Sang Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.46 no.1
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    • pp.146-151
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    • 2017
  • Quality characteristics (moisture, protein, ash, bulk density, falling number, damaged kernel, and foreign material) of 443 domestic wheat samples harvested between 2011 and 2013 were compared with those of 160 imported wheat samples from the United States, Australia, and Canada. Moisture content of domestic wheat (10.9~13.9%) was generally higher than that of imported wheat (8.0~12.6%). Large variation in protein content was found in domestic wheat compared to imported wheat even though variation in protein content of domestic wheat tended to decrease every year, implying quality control efforts for domestic wheat. A similar trend was observed in ash content, which was approximately 0.1% higher in domestic wheat kernels over 3 years. Imported wheat samples had a falling number of 300 or above. On the other hand, some domestic wheat samples had a falling number of 300, which meant low quality of wheat kernels. Generally, quality variations in domestic wheat kernels decreased over the years; however, it is necessary to maintain minimum requirements of moisture content and falling number for high and consistent quality domestic wheat.

Evaluation of Nursing Educational Objectives Achievement & Related Factors in Nurses Within Five Years After Graduation: Focusing on Critical Thinking Disposition and Clinical Competence (일개대학 간호학과 졸업 후 5년 이내 간호사의 교육목표 달성도와 영향요인 -비판적 사고 성향과 임상수행능력을 중심으로)

  • Han, Mi-Hyun;Jeong, Seung-Eun;Kim, Jee-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.836-846
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    • 2018
  • The purpose of this study was to evaluate nursing educational objectives achievement, critical thinking disposition, and clinical competence and their relationships in nurses within five years after graduation. Subjects were 82 nurses who graduated one nursing college within five years and 68 managers in nursing unit of hospital. Questions were given to nurses. They reported their achievement of educational objectives of the nursing college, critical thinking disposition and clinical competence. Nursing unit managers received the same questions to evaluate nurses working at their unit. Data were collected from January to march 2014 and analyzed by descriptive statistics, t-test, ANOVA, Pearson correlation and multiple regression with SPSS/WIN 23.0 program. Mean scores for achievement of educational objectives, critical thinking disposition, and clinical competence were $3.60{\pm}0.60$, $3.46{\pm}0.28$, and $4.17{\pm}0.56$, respectively. Educational objectives achievement showed significant correlations with critical thinking disposition (r = 0.52, p <. 001) and clinical competence (r = 0.52, p < .001). Regression analysis showed that critical thinking disposition (${\beta}=.30$, p = .018) and clinical competence (${\beta}=.26$, p = .029) were significant factors for predicting educational objectives achievement. Manager's evaluation score for educational objectives achievement and clinical competence was higher than graduated nurses' report (p < .001). This could be used as a feed- back to reset educational objectives and upgrade the curriculum. These study results could be used to, establish strategies to improve educational objectives achievement.

A study of the development of macrovascular complications and factors related to these complications in young adults with childhood/adolescence-onset type 1 diabetes mellitus (소아청소년기에 1형 당뇨병으로 진단된 젊은 성인에서 대혈관 합병증의 발생과 이에 연관된 인자에 대한 연구)

  • Kang, Min Jae;Kim, Joo Hwa;Chung, Hye Rim;Lee, Young Ah;Shin, Choong Ho;Yang, Sei Won;Kim, You Yeh;Jin, Seon Mi;Noh, Chung Il
    • Clinical and Experimental Pediatrics
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    • v.52 no.2
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    • pp.220-226
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    • 2009
  • Purpose : Macrovascular complications are the main cause of mortality in type 1 diabetes mellitus (T1DM). The purpose of this study was to clarify the presence of early vascular changes and to assess the risk factors of macrovascular complications in young adults with T1DM diagnosed in childhood and adolescence. Methods : Seventy-two patients ($23.9{\pm}2.4$ years) with T1DM diagnosed before 18 years of age and twenty normal controls were included. The incidence of hypertension, dyslipidemia, and other risk factors of macrovascular complication were reviewed. Flow-mediated vasodilation (FMD) and mean intima-media thickness (IMT) measured by ultrasound were compared between patients and control subjects, and their correlations with macrovascular risk factors were analyzed. Results : Of the 72 patients, 32 (44.4%) had hypertension. The proportions of maleness (P=0.03) and mean body mass index (P=0.04) were higher in the hypertensive patients than in normotensive patients. Thirty-one (N=69, 44.9%) patients had dyslipidemia and LDL-cholesterol was positively correlated with mean HbA1c (r=0.32, P=0.008) and total daily insulin dose (r=0.27, P=0.02). The mean IMT was significantly higher in patients than in control subjects ($0.43{\pm}0.06$ mm vs $0.39{\pm}0.06$ mm, P=0.03). There was no difference in the value of FMD between patients and controls, but the duration of the disease after pubertal onset was negatively correlated with FMD (r=-0.34, P=0.01). Conclusion : Hypertension, dyslipidemia and atherosclerotic vascular change were observed in young adults with T1DM diagnosed during childhood and adolescence; this strongly suggests that meticulous screening of macrovascular complications and control of their risk factors should be conducted.