• 제목/요약/키워드: miR-23a

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간호사의 AIDS에 대한 지식, 태도 및 예방적 행위 (The Relationships between Knowledge, Attitude and Prevention Behaviors to AIDS in Nurses)

  • 성미혜
    • 한국직업건강간호학회지
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    • 제17권1호
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    • pp.14-22
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    • 2008
  • Purpose: The purpose of this descriptive study was to examine the knowledge, attitudes and prevention behavior to AIDS of nurses. Method: The subject of this study were 217 nurses in Busan. Data was analyzed by using descriptive statistics, t-test, ANOVA, Pearson's correlation, and Scheffe's test. Results: Total knowledge of AIDS(mean score was 6.71 out of 12) was average. Total attitudes of AIDS(mean score was 13.16 out of 25)was average. Prevention behaviors were above average(mean score was 57.63 out of 75). According to the results of analyzing the difference between general characteristics of the subject and AIDS related knowledge, attitudes and prevention behaviors, a significant difference was present with religion(p<.05) in attitudes score; with age(p<.001), marital status(p<.001), education level(p<.05), position(p<.05) and clinical experience(p<.05) in prevention behaviors. According to the results of analyzing the difference between AIDS related characteristics of the subject and AIDS related knowledge, attitudes and perceived behaviors, a significant difference was present with experience in taking care of HIV/AIDS patients(t=2.19, p<.05) in attitudes score; and experience in HIV positive after care(t=-2.64, p<.01) and general nursing training about AIDS(t=2.23, p<.01). There was a positive correlation among knowledge score and attitudes score(r=.170, p<.05). Conclusion: These findings suggested that AIDS education and training programs should be developed and run for nurses. Expecially, health education related with AIDS is needed in young and less experienced nurses. In following such a program, there will be greater compliance with prevention behaviors. Furthermore, it is necessary to provide work-related guidelines regarding AIDS for nurses.

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Marker compounds contents of Salvia miltiorrhiza Radix depending on the cultivation regions

  • Seong, Gi-Un;Kim, Mi-Yeon;Chung, Shin-Kyo
    • Journal of Applied Biological Chemistry
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    • 제62권2호
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    • pp.129-135
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    • 2019
  • Salvia miltiorrhiza Radix is cultivated in Korea and China and is traditionally used to treat cardiovascular diseases. In this study, we developed and validated a quantitative analysis method for S. miltiorrhiza Radix using high-performance liquid chromatography (HPLC). Identification was performed using ultra performance liquid chromatography-tandem mass spectrometry. For quantitative analysis, we used seven marker compounds. Separation conditions for HPLC were optimized using an ODS column with gradient conditions of 1% formic acid in distilled water and 1% formic acid in acetonitrile, with a flow rate of 0.8 mL/min and a detection wavelength of 280 nm. This method showed good linearity ($R^2=0.9998$), precision (relative standard deviation ${\leq}3.3%$), accuracy (recovery of 94.16-102.89%), limit of detection ($7.53{\mu}g/mL$), and limit of quantification ($23.71{\mu}g/mL$). This approach successfully quantified marker compounds in S. miltiorrhiza Radix. The individual marker compounds were identified by comparing the molecular masses and retention times with does standard compounds. Marker compound contents of S. miltiorrhiza Radix were investigated with different cultivation regions. Seven marker compounds were detected and quantified in all samples. Among them, salvianolic acid B showed the highest contents and it ranged from 4.13 to 7.15%. The salvianolic acid B content (7.15%) of marker compound was the highest in Bonghwa, and the tanshinone IIA content (1.90%) was the highest in Pohang. The results of marker compounds and developed method were intended to provide a favorable reference for the study of S. miltiorrhiza Radix from different regions of Korea.

성인 혈우병 환자와 운동: 체계적 문헌고찰과 메타분석 (Exercise and adults with hemophilia: a systematic review and meta-analysis)

  • 김두영;전미양;은영;정다인
    • Journal of Korean Biological Nursing Science
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    • 제26권1호
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    • pp.1-15
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    • 2024
  • Purpose: This study aimed to evaluate the effectiveness of exercise in patients with hemophilia. Methods: We carried out a systematic review and meta-analysis in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines. A literature search was conducted of published randomized controlled trials for exercise interventions from January 1, 2014 to March 15, 2023. To estimate the size of the effects of exercise, a meta-analysis was performed using the R package "meta." Results: Five databases were searched to obtain articles published in Korean or English. Of 1,150 articles reviewed, 13 were included in the systematic review and 9 in the meta-analysis. The risk of bias was assessed using RoB 2.0. The overall effect sizes of exercise interventions, calculated as the standardized mean difference, were -0.11 (95% confidence interval [CI] = -1.41 to -1.20) for pain, -2.13 (95% CI = -3.33 to -0.93) for joint health, 9.96 (95% CI = 7.51 to 12.28) for physical activity, and 0.59 (95% CI = -0.39 to -1.56) for quality of life. Conclusion: These findings suggest that exercise is useful for improving the joint health and physical activity of patients with hemophilia. Thus, it is necessary to develop and apply exercise interventions for patients with hemophilia to reduce their pain and improve their quality of life.

델파이 기법을 이용한 대표적인 한국의 맛과 음식에 관한 연구 (Exploring Korean Typical Tastes, Flavors and Foods Using Delphi Technique)

  • 차성미;정라나;정서진;김광옥;한귀정;이새롬
    • 한국식품조리과학회지
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    • 제26권2호
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    • pp.155-164
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    • 2010
  • The present study attempted to conceptualize Korean typical tastes, flavors and foods and to gather professionals' opinions about the globalization of Korean foods. A total of 23 experts participated in a three round survey using the Delphi technique, which was used to integrate and share the professional ideas of each expert. The survey was categorized into two parts: 1. Korean typical tastes and flavors, 2. Korean typical foods. According to the results, 'hot chili pepper', 'Kimchi', 'soy sauce', and 'garlic' were represented as Korean typical tastes and flavors. Also 'harmonized' was determined to be a type of food that should be introduced to foreigners and, 'sweet' and 'tart' were shown to also be liked by foreigners. In addition, 'neobiani', 'kalbi', 'bibimbap', 'kimchi', 'japchae', and 'neobiani' were categorized as typical Korean foods, foods that should be introduced to foreigners, and foods that would be liked by foreigners. These results showed that appropriate foods should be globalized and R&D should be expanded to determine the preferences of foreigners in terms of tastes and flavors.

제주 감귤식초 발효균주 선발 (Sensory Characteristics of Citrus Vinegar fermented by Gluconacetobacter hansenii CV1)

  • 김미림;최경호
    • 한국식품조리과학회지
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    • 제21권2호
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    • pp.243-249
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    • 2005
  • 제주산 감귤과즙을 이용하여 감귤식초를 제조할 목적으로 식초산 발효균 CV1과 CV2를 분리하고 식초산 생성능력을 산업적으로 이용되고 있는 균주와 비교 검정하고 165 rDNA 염기서열을 분석하고 동정하였다. 분리균은 8일간의 발효에 의하여 산도 $5.5\%$ 이상의 식초산을 생성하였으며, 감귤식초 발효에는 사과식초나 감식초 발효에 이용되고 있는 균주 보다 더욱 적합한 것으로 판정되었다. 분리한 균주는 Gluconacetobacter hanenii(CV2) 및 G. hanenii의 변이주(CV1)로 동정되었다.

Prediction of Solar Photovoltaic Power Generation by Weather Using LSTM

  • Lee, Saem-Mi;Cho, Kyu-Cheol
    • 한국컴퓨터정보학회논문지
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    • 제27권8호
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    • pp.23-30
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    • 2022
  • 딥러닝은 주가 및 농산물 가격 예측과 같이 데이터를 분석해 일련의 규칙을 발견하고 미래를 예상해 우리의 삶에서 다양한 도움을 주고 있다. 본 연구는 태양광 에너지 사용의 중요성이 늘어나는 상황에서 기상에 따른 태양광 발전 실적을 딥러닝을 통해 분석하고 발전량을 예측한다. 본 연구에서는 시계열 데이터 예측에서 두각을 나타내고 있는 LSTM(Long Short Term Memory network)을 사용한 모델을 제안하며 이미지를 비롯한 다양한 차원의 데이터를 분석할 때 사용되는 CNN(Convolutional Neural Network)과 두 모델을 결합한 CNN-LSTM과의 성능을 비교한다. 세 가지 모델의 성능은 태양광 발전 실적의 실제값과 딥러닝을 통해 예측한 값으로 MSE, RMSE, 결정계수를 계산하여 비교하였고 그 결과 LSTM 모델의 성능이 가장 우수한 것으로 나타났다. 따라서 본 연구는 LSTM을 사용한 태양광 발전량 예측을 제안한다.

월경전증후군에 대한 침 치료의 효과 : 체계적 문헌고찰과 메타분석 (Acupuncture for Premenstrual Syndrome: A Systematic Review and Meta-analysis)

  • 김안나;김영은;이은희;손미주
    • 대한한방부인과학회지
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    • 제36권3호
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    • pp.154-172
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    • 2023
  • Objectives: This study aimed to assess the clinical evidence supporting the use of acupuncture (AC) for premenstrual syndrome (PMS). Methods: We searched randomized controlled trials (RCTs) that used AC for PMS in 9 databases (PubMed, EMBASE, Cochrane Library, CINAHL, CNKI, CiNii, SCIENCE ON, KoreaMed, OASIS) from their inception to July 2022. Results: We identified 1,168 studies, of which 15 RCTs met the inclusion criteria. The risk of bias in the included studies was relatively unclear or high. Meta-analysis of 3 RCTs showed that the AC group had a significantly higher effective rate than the Medroxyprogesterone group (RR 1.48, 95% CI (1.23, 1.78), p<0.0001). Meta-analysis of 2 RCTs showed that there was no statistically significant difference between the AC group and the Sham AC group in the effective rate (RR 4.72, 95% CI (0.88, 25.36), p=0.07). In a review of individual studies, the AC group was more effective than the control group in terms of the effective rate, symptom scale, quality of life, adverse events, and recurrence rate. Conclusions: The AC group was more effective than general treatments groups such as sham AC, western medicine, and dietary supplements, and there were no serious adverse events. However, the evidence on the effectiveness and safety of acupuncture for PMS was inconclusive due to the small number of included studies and low quality. Therefore, systematic reviews based on more rigorously designed randomized clinical trials are needed in the future to properly evaluate the effect of AC on PMS.

Molecular detection and genotype analysis of Kudoa septempunctata from food poisoning outbreaks in Korea

  • Gyung-Hye Sung;In-Ji Park;Hee-Soo Koo;Eun-Hee Park;Mi-Ok Lee
    • Parasites, Hosts and Diseases
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    • 제61권1호
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    • pp.15-23
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    • 2023
  • Concerns about foodborne illnesses caused by Kudoa septempunctata are steadily growing, but reports of K. septempunctata in clinical and food specimens related to food poisoning in Korea are limited. This study aimed to genetically identify K. septempunctata in patients with acute diarrhea and in clinical and food samples related to food poisoning caused by sashimi consumption. Both real-time and nested polymerase chain reaction assays were performed to detect K. septempunctata 18S and 28S rDNA genes in the stools of 348 patients with acute diarrhea, 11 samples (6 stool and 5 rectal swab samples) from patients with food poisoning, and 2 raw Paralichthys olivaceus samples collected from a restaurant where a food poisoning incident occurred. K. septempunctata was identified in 5 clinical specimens (4 stools and 1 rectal swab) and 1 P. olivaceus sashimi sample. All detected K. septempunctata were of genotype ST3. This is the first study to identify K. septempunctata in both patients and food samples with epidemiological relevance in Korea, providing evidence that it is a pathogen that causes food poisoning. Also, this is the first study to confirm the presence of K. septempunctata genes in rectal swabs. Despite continuing suspected occurrences of Kudoa foodborne outbreaks, the rate of identification of K. septempunctata is very low. One reason for this is the limitation in obtaining stool and vomit samples for the diagnosis of Kudoa infection. We strongly suggest the inclusion of rectal swabs among the diagnostic specimens for Kudoa food poisoning.

${\beta}$-Glucanase를 이용한 국내산 찰보리 전분 추출공정의 최적화 및 추출 전분의 주요 이화학적 특성에 관한 연구 (Optimization of ${\beta}$-Glucanase-assisted Extraction of Starch from Domestic Waxy Barley and Its Physicochemical Properties)

  • 정용선;배재석;김정원;이의석;이기택;이미자;홍순택
    • 동아시아식생활학회지
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    • 제23권6호
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    • pp.789-798
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    • 2013
  • In the present study, optimization on ${\beta}$-glucanase-assisted extraction was made in order to isolate waxy barley starch from domestic cultivar using the D-optimal design suitable for response surface methodology (RSM). The results demonstrated that the amount of enzyme was found to be a major influencing factor on the extraction yield, which was substantially increased by increasing the amount of enzyme. It was also influenced by the reaction time and amount of water addition; however, the two factors were less influential than the amount of enzyme. The optimized condition by RSM for the reaction time was found to be 2.63 hours and amount of enzyme 1.7%, and amount of water addition 4.38 times the weight of raw material. With the enzyme treatment, the starch content in residues (R), particularly in R1 and R5, was reduced considerably, resulting in an increase in the extraction yield and therefore primarily and effectively releasing B-type starch small granule confirmed by scanning electronic microscopy. In addition, the study determined the physicochemical properties of isolated waxy starch (i.e., purity, water adsorption capacity, thermal properties, rheology and starch morphology) and compared them with those from the enzyme-not treated sample. It was found that they were almost similar to each other, except for the purity of starch, which was lower in the enzyme-treated sample than in the enzyme-not treated one.

한국 담배규제 정책의 평가: 담배규제정책 전문가 의견 조사를 토대로 (Evaluation of Tobacco Control Policy in Korea: Development and Application of the Korean Tobacco Index for Policy Monitoring and Evaluation)

  • 황지은;오유미
    • 보건행정학회지
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    • 제24권4호
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    • pp.342-348
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    • 2014
  • Background: Due to lack of regular and systematic evaluation tool, Korea's tobacco control policy has not been examined its overall process of implementation including efficiency and adequacy of the policies. This study developed policy monitoring and evaluation model to assess policy implementation and effectiveness of tobacco control in Korea. Methods: Based on World Health Organization operational manual for assessment, MPOWER (monitor tobacco use and prevention policies, protect from tobacco smoke, offer help to quit tobacco use, warn about the dangers of tobacco, enforce bans on tobacco advertising promotion and sponsorship, and raise taxes on tobacco) related policies were reviewed by rating policy efforts, programme management, people (human resources and their development), provision of organization, provision of fund and partnerships (range, 0 to 5). Results: As a result of the experts' assessment, overall Korean tobacco control policies scored 2.61 points, which is poor. In relation to each 'MPOWER' policies, 'W' scored the highest points (2.93), followed by 'O' (2.91), 'M' (2.87), 'P' (2.86), and 'E' (2.23). 'R' scored the lowest points of 1.87, meaning government efforts in tobacco price policy is insufficient. Conclusion: This study concludes that Korean tobacco control policy should strengthen tax and price measures, while programme infrastructure, people, and funds for policy enforcement should be secured. Furthermore, rather than focusing on one specific measure, a balanced approach reflecting various aspects of tobacco controls should be considered in order to decrease smoking rates and prevent smoking initiation.